المؤلفون: Paweł Zajdel (2606617), Katarzyna Grychowska (2658958), Szczepan Mogilski (4490899), Rafał Kurczab (1312479), Grzegorz Satała (805228), Ryszard Bugno (5727881), Tomasz Kos (420162), Joanna Gołębiowska (10291051), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Séverine Chaumont-Dubel (10291045), Xavier Bantreil (1887601), Maciej Pawłowski (1792099), Jean Martinez (150107), Gilles Subra (1494619), Frédéric Lamaty (1498096), Philippe Marin (460346), Andrzej J. Bojarski (499184), Piotr Popik (292215)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://figshare.com/articles/journal_contribution/Structure-Based_Design_and_Optimization_of_FPPQ_a_Dual-Acting_5_HT_sub_3_sub_and_5_HT_sub_6_sub_Receptor_Antagonist_with_Antipsychotic_and_Procognitive_Properties/16553317

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s001

المؤلفون: Paweł Zajdel, Katarzyna Grychowska, Szczepan Mogilski, Rafał Kurczab, Grzegorz Satała, Ryszard Bugno, Tomasz Kos, Joanna Gołębiowska, Natalia Malikowska-Racia, Agnieszka Nikiforuk, Séverine Chaumont-Dubel, Xavier Bantreil, Maciej Pawłowski, Jean Martinez, Gilles Subra, Frédéric Lamaty, Philippe Marin, Andrzej J. Bojarski, Piotr Popik

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://doi.org/10.1021/acs.jmedchem.1c00224.s001

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s001

المؤلفون: Paweł Zajdel (2606617), Katarzyna Grychowska (2658958), Szczepan Mogilski (4490899), Rafał Kurczab (1312479), Grzegorz Satała (805228), Ryszard Bugno (5727881), Tomasz Kos (420162), Joanna Gołębiowska (10291051), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Séverine Chaumont-Dubel (10291045), Xavier Bantreil (1887601), Maciej Pawłowski (1792099), Jean Martinez (150107), Gilles Subra (1494619), Frédéric Lamaty (1498096), Philippe Marin (460346), Andrzej J. Bojarski (499184), Piotr Popik (292215)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://figshare.com/articles/dataset/Structure-Based_Design_and_Optimization_of_FPPQ_a_Dual-Acting_5_HT_sub_3_sub_and_5_HT_sub_6_sub_Receptor_Antagonist_with_Antipsychotic_and_Procognitive_Properties/16553323

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s003

المؤلفون: Paweł Zajdel (2606617), Katarzyna Grychowska (2658958), Szczepan Mogilski (4490899), Rafał Kurczab (1312479), Grzegorz Satała (805228), Ryszard Bugno (5727881), Tomasz Kos (420162), Joanna Gołębiowska (10291051), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Séverine Chaumont-Dubel (10291045), Xavier Bantreil (1887601), Maciej Pawłowski (1792099), Jean Martinez (150107), Gilles Subra (1494619), Frédéric Lamaty (1498096), Philippe Marin (460346), Andrzej J. Bojarski (499184), Piotr Popik (292215)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://figshare.com/articles/dataset/Structure-Based_Design_and_Optimization_of_FPPQ_a_Dual-Acting_5_HT_sub_3_sub_and_5_HT_sub_6_sub_Receptor_Antagonist_with_Antipsychotic_and_Procognitive_Properties/16553320

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s002

المؤلفون: Paweł Zajdel (2606617), Katarzyna Grychowska (2658958), Szczepan Mogilski (4490899), Rafał Kurczab (1312479), Grzegorz Satała (805228), Ryszard Bugno (5727881), Tomasz Kos (420162), Joanna Gołębiowska (10291051), Natalia Malikowska-Racia (10875226), Agnieszka Nikiforuk (420161), Séverine Chaumont-Dubel (10291045), Xavier Bantreil (1887601), Maciej Pawłowski (1792099), Jean Martinez (150107), Gilles Subra (1494619), Frédéric Lamaty (1498096), Philippe Marin (460346), Andrzej J. Bojarski (499184), Piotr Popik (292215)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Physiology, Pharmacology, Cancer, Mental Health, Infectious Diseases, Chemical Sciences not elsewhere classified, rational polypharmacological approach, decent brain penetration, ameliorates cognitive deficits, known procognitive effects, 6 , 3 , displays procognitive properties, 5 ‑ ht, fppq , neutral antagonist 5, procognitive properties, neutral 5, target 5, acting 5, shows selectivity, psychiatric disorders, like symptoms, inhibits phencyclidine, hybridization strategy, gs pathway

Relation: https://figshare.com/articles/dataset/Structure-Based_Design_and_Optimization_of_FPPQ_a_Dual-Acting_5_HT_sub_3_sub_and_5_HT_sub_6_sub_Receptor_Antagonist_with_Antipsychotic_and_Procognitive_Properties/16553326

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00224.s004