يعرض 1 - 20 نتائج من 40 نتيجة بحث عن '"greater proportion"', وقت الاستعلام: 0.45s تنقيح النتائج
  1. 1
  2. 2
    Academic Journal
  3. 3
  4. 4
    Academic Journal
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9
  10. 10
  11. 11
  12. 12
  13. 13
  14. 14
  15. 15
    Academic Journal

    المساهمون: Benson, J. C., Nardi, V., Madhavan, A. A., Bois, M. C., Saba, L., Savastano, L., Lerman, A., Lanzino, G.

    مصطلحات موضوعية: BACKGROUND AND PURPOSE: The CTA “rim sign” has been proposed as an imaging marker of intraplaque hemorrhage in carotid plaques. This study sought to investigate such findings using histopathologic confirmation. MATERIALS AND METHODS: Included patients had CTA neck imaging ,1 year before carotid endarterectomy. On imaging, luminal stenosis and the presence of adventitial (,2-mm peripheral) and “bulky” ($2-mm) calcifications, total plaque thickness, soft-tissue plaque thickness, calcification thickness, and the presence of ulcerations were assessed. The rim sign was defined as the presence of adventitial calcifications with internal soft-tissue plaque of $2 mm in maximum thickness. Carotid endarterectomy specimens were assessed for both the presence and the proportional makeup of lipid material, intraplaque hemorrhage, and calcification. RESULTS: Sixty-seven patients were included. Twenty-three (34.3%) were women, the average age was 70.4 years. Thirty-eight (57.7%) plaques had a rim sign on imaging, with strong interobserver agreement (k = 0.85). A lipid core was present in 64 (95.5%) plaques (average, 22.2% proportion of plaque composition), intraplaque hemorrhage was present in 52 (77.6%), making up, on average, 13.7% of the plaque composition. The rim sign was not associated with the presence of intraplaque hemorrhage (P = .11), however, it was associated with a greater proportion of intraplaque hemorrhage in a plaque (P = .049). The sensitivity and specificity of the rim sign for intraplaque hemorrhage were 61.5% and 60.0%, respectively. CONCLUSIONS: The rim sign is not associated with the presence of intraplaque hemorrhage on histology. However, it is associated with a higher proportion of hemorrhage within a plaque and therefore may be a biomarker of more severe intraplaque hemorrhage, if present.

    Relation: info:eu-repo/semantics/altIdentifier/pmid/35210276; info:eu-repo/semantics/altIdentifier/wos/WOS:000763601400001; volume:43; issue:3; firstpage:429; lastpage:434; numberofpages:6; journal:AJNR, AMERICAN JOURNAL OF NEURORADIOLOGY; https://hdl.handle.net/11584/347282; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85126388695; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910788/

  16. 16
  17. 17
    Image
  18. 18
    Image
  19. 19
    Image
  20. 20
    Image