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1Academic Journal
المؤلفون: Weiwei Ma, Honggu Chen, Zhiwen Zhang, Yong Xiong
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Virology, sup >&# 8722, prevalent musculoskeletal disorder, precise mechanisms underlying, observed significant associations, ldl cholesterol levels, gwas summary data, genetic variants associated, 180 × 10, potential causal relationship, particularly lipid metabolism, genetically proxied lipid, genetically predicted lipid, commonly targeted lipid, potential therapeutic use,
+osteoarthritis%22">xlink "> osteoarthritis, knee osteoarthritis specifically, lowering drug targets, %22">xlink ">, osteoarthritis outcomes, knee osteoarthritis, lowering drugs, lowering agents -
2Academic Journal
المؤلفون: Weiwei Ma, Honggu Chen, Zhiwen Zhang, Yong Xiong
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Virology, sup >&# 8722, prevalent musculoskeletal disorder, precise mechanisms underlying, observed significant associations, ldl cholesterol levels, gwas summary data, genetic variants associated, 180 × 10, potential causal relationship, particularly lipid metabolism, genetically proxied lipid, genetically predicted lipid, commonly targeted lipid, potential therapeutic use,
+osteoarthritis%22">xlink "> osteoarthritis, knee osteoarthritis specifically, lowering drug targets, %22">xlink ">, osteoarthritis outcomes, knee osteoarthritis, lowering drugs, lowering agents -
3Academic Journal
المؤلفون: Weiwei Ma, Honggu Chen, Zhiwen Zhang, Yong Xiong
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Virology, sup >&# 8722, prevalent musculoskeletal disorder, precise mechanisms underlying, observed significant associations, ldl cholesterol levels, gwas summary data, genetic variants associated, 180 × 10, potential causal relationship, particularly lipid metabolism, genetically proxied lipid, genetically predicted lipid, commonly targeted lipid, potential therapeutic use,
+osteoarthritis%22">xlink "> osteoarthritis, knee osteoarthritis specifically, lowering drug targets, %22">xlink ">, osteoarthritis outcomes, knee osteoarthritis, lowering drugs, lowering agents -
4Academic Journal
المؤلفون: Weiwei Ma, Honggu Chen, Zhiwen Zhang, Yong Xiong
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Virology, sup >&# 8722, prevalent musculoskeletal disorder, precise mechanisms underlying, observed significant associations, ldl cholesterol levels, gwas summary data, genetic variants associated, 180 × 10, potential causal relationship, particularly lipid metabolism, genetically proxied lipid, genetically predicted lipid, commonly targeted lipid, potential therapeutic use,
+osteoarthritis%22">xlink "> osteoarthritis, knee osteoarthritis specifically, lowering drug targets, %22">xlink ">, osteoarthritis outcomes, knee osteoarthritis, lowering drugs, lowering agents -
5
المؤلفون: Weiwei Ma, Honggu Chen, Zhiwen Zhang, Yong Xiong
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Virology, sup >&# 8722, prevalent musculoskeletal disorder, precise mechanisms underlying, observed significant associations, ldl cholesterol levels, gwas summary data, genetic variants associated, 180 × 10, potential causal relationship, particularly lipid metabolism, genetically proxied lipid, genetically predicted lipid, commonly targeted lipid, potential therapeutic use,
+osteoarthritis%22">xlink "> osteoarthritis, knee osteoarthritis specifically, lowering drug targets, %22">xlink ">, osteoarthritis outcomes, knee osteoarthritis, lowering drugs, lowering agents -
6Image
المؤلفون: Weiwei Ma, Honggu Chen, Zhiwen Zhang, Yong Xiong
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Virology, sup >&# 8722, prevalent musculoskeletal disorder, precise mechanisms underlying, observed significant associations, ldl cholesterol levels, gwas summary data, genetic variants associated, 180 × 10, potential causal relationship, particularly lipid metabolism, genetically proxied lipid, genetically predicted lipid, commonly targeted lipid, potential therapeutic use,
+osteoarthritis%22">xlink "> osteoarthritis, knee osteoarthritis specifically, lowering drug targets, %22">xlink ">, osteoarthritis outcomes, knee osteoarthritis, lowering drugs, lowering agents -
7Image
المؤلفون: Weiwei Ma, Honggu Chen, Zhiwen Zhang, Yong Xiong
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Virology, sup >&# 8722, prevalent musculoskeletal disorder, precise mechanisms underlying, observed significant associations, ldl cholesterol levels, gwas summary data, genetic variants associated, 180 × 10, potential causal relationship, particularly lipid metabolism, genetically proxied lipid, genetically predicted lipid, commonly targeted lipid, potential therapeutic use,
+osteoarthritis%22">xlink "> osteoarthritis, knee osteoarthritis specifically, lowering drug targets, %22">xlink ">, osteoarthritis outcomes, knee osteoarthritis, lowering drugs, lowering agents الاتاحة: https://doi.org/10.1371/journal.pone.0293960.g002
https://figshare.com/articles/figure/Inverse-variance_weighted_Mendelian_randomization_IVW-MR_association_between_low-_density_lipoprotein_LDL_cholesterol_mediated_by_gene_3-hydroxy-3-methylglutaryl-coenzyme_A_reductase_HMGCR_Niemann-Pick_C1-Like_1_NPC1L1_proprotein_convertase/25307139 -
8
المؤلفون: Weiwei Ma, Honggu Chen, Zhiwen Zhang, Yong Xiong
مصطلحات موضوعية: Biochemistry, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Virology, sup >&# 8722, prevalent musculoskeletal disorder, precise mechanisms underlying, observed significant associations, ldl cholesterol levels, gwas summary data, genetic variants associated, 180 × 10, potential causal relationship, particularly lipid metabolism, genetically proxied lipid, genetically predicted lipid, commonly targeted lipid, potential therapeutic use,
+osteoarthritis%22">xlink "> osteoarthritis, knee osteoarthritis specifically, lowering drug targets, %22">xlink ">, osteoarthritis outcomes, knee osteoarthritis, lowering drugs, lowering agents -
9
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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10Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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11Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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12Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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13Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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14Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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15Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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16Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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17Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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18Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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19Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
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20Image
المؤلفون: Zhican Huang, Ting Cui, Jin Yao, Yutong Wu, Jun Zhu, Xin Yang, Li Cui, Haiyan Zhou
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Virology, two comprehensive meta, sup >&# 8722, nightingale health 2020, based mendelian randomization, 81 × 10, 66 × 10, 50 × 10, 43 × 10, obtained genetic variation, modified drug targets, drug targets related, observed significant associations, genetically predicted lipid, genetically predicted 3, significant causal relationship, modifying drug targets, target mr analyses, causal relationship, modifying medications, modifying drugs, causal connection
Relation: https://figshare.com/articles/figure/Results_of_SMR_analysis_of_drug_targets_and_RA_/25307441