المؤلفون: Beata Bugara, Małgorzata Durbas, Maja Kudrycka, Agata Malinowska, Irena Horwacik, Hanna Rokita

المصدر: Frontiers in Pharmacology, Vol 15 (2024)

مصطلحات موضوعية: GD2 ganglioside-binding antibody, human neuroblastoma cells, PHLDA1 silencing, mass spectrometry, AUTS2, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1351536/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/4f50ebe42f5d426ead4004b9221299a9

المؤلفون: Kyle S. Gregory, K. Ravi Acharya

المصدر: Toxins; Volume 15; Issue 2; Pages: 92

مصطلحات موضوعية: botulinum neurotoxin, cell-binding domain, ganglioside binding, synaptic vesicle glycoprotein 2, structural analysis

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Bacterial Toxins; https://dx.doi.org/10.3390/toxins15020092

الاتاحة: https://doi.org/10.3390/toxins15020092

المؤلفون: Kyle S. Gregory, Sai Man Liu, K. Ravi Acharya

المصدر: FEBS Open Bio, Vol 10, Iss 3, Pp 298-305 (2020)

مصطلحات موضوعية: botulinum neurotoxin, cell binding domain, crystallography, ganglioside binding, protein structure, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2211-5463

URL الوصول: https://doaj.org/article/1cdef2f317864057b51401ece16369a1

المؤلفون: Gregory, Kyle, Newell, Anna, Mojanaga, Otsile, Liu, Sai Man, Acharya, R

المصدر: Gregory , K , Newell , A , Mojanaga , O , Liu , S M & Acharya , R 2022 , ' Crystal Structures of the Clostridium botulinum Neurotoxin A6 Cell Binding Domain Alone and in Complex with GD1a Reveal Significant Conformational Flexibility ' , International Journal of Molecular Sciences , vol. 23 , no. 17 , 9620 . https://doi.org/10.3390/ijms23179620

مصطلحات موضوعية: botulinum neurotoxin, cell-binding domain, conformational flexibility, crystal structure, ganglioside binding, redox switch, subtype A6, /dk/atira/pure/subjectarea/asjc/1500/1503, name=Catalysis, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1600/1607, name=Spectroscopy, /dk/atira/pure/subjectarea/asjc/1700/1706, name=Computer Science Applications, /dk/atira/pure/subjectarea/asjc/1600/1606, name=Physical and Theoretical Chemistry, /dk/atira/pure/subjectarea/asjc/1600/1605, name=Organic Chemistry, /dk/atira/pure/subjectarea/asjc/1600/1604, name=Inorganic Chemistry

Relation: https://researchportal.bath.ac.uk/en/publications/dcbadedd-941d-4e5a-97bd-4b0e02ad3d4d

الاتاحة: https://researchportal.bath.ac.uk/en/publications/dcbadedd-941d-4e5a-97bd-4b0e02ad3d4d
https://doi.org/10.3390/ijms23179620
http://www.scopus.com/inward/record.url?scp=85137563721&partnerID=8YFLogxK

المؤلفون: Gregory, Kyle, Mahadeva, Tejaswini, Liu, Sai Man, Acharya, R

المصدر: Gregory , K , Mahadeva , T , Liu , S M & Acharya , R 2022 , ' Structural features of Clostridium botulinum neurotoxin subtype A2 cell binding domain ' , Toxins , vol. 14 , no. 5 , 356 . https://doi.org/10.3390/toxins14050356

مصطلحات موضوعية: botulinum neurotoxin, cell‐binding domain, crystal structure, ganglioside binding, redox switch, subtype A2, /dk/atira/pure/subjectarea/asjc/3000/3005, name=Toxicology, /dk/atira/pure/subjectarea/asjc/2300/2307, name=Health, Toxicology and Mutagenesis

Relation: https://researchportal.bath.ac.uk/en/publications/df3968c3-c6e3-49e3-95a8-65fb3d55ca73

الاتاحة: https://researchportal.bath.ac.uk/en/publications/df3968c3-c6e3-49e3-95a8-65fb3d55ca73
https://doi.org/10.3390/toxins14050356
http://www.scopus.com/inward/record.url?scp=85130928565&partnerID=8YFLogxK

المؤلفون: Gregory, Kyle, Mojanaga, Otsile, Man Liu, Sai, Acharya, R

المصدر: Gregory , K , Mojanaga , O , Man Liu , S & Acharya , R 2022 , ' Crystal structures of botulinum neurotoxin subtypes A4 and A5 cell binding domains in complex with receptor ganglioside ' , Toxins , vol. 14 , no. 2 , 129 . https://doi.org/10.3390/toxins14020129

مصطلحات موضوعية: Botulinum neurotoxin, Cell binding domain, Crystal structure, Ganglioside binding, Subtypes A4 and A5, /dk/atira/pure/subjectarea/asjc/3000/3005, name=Toxicology, /dk/atira/pure/subjectarea/asjc/2300/2307, name=Health, Toxicology and Mutagenesis

Relation: https://researchportal.bath.ac.uk/en/publications/0d63b38b-f5f2-4134-9ff6-a1f700a25886

الاتاحة: https://researchportal.bath.ac.uk/en/publications/0d63b38b-f5f2-4134-9ff6-a1f700a25886
https://doi.org/10.3390/toxins14020129
http://www.scopus.com/inward/record.url?scp=85124551747&partnerID=8YFLogxK

المؤلفون: Katja Venko, Marjana Novič, Veronika Stoka, Eva Žerovnik

المصدر: Frontiers in Molecular Neuroscience, Vol 14 (2021)

مصطلحات موضوعية: amyloid-forming proteins, amyloidogenic regions, transmembrane regions, amino-acid sequence predictors, cholesterol and ganglioside binding motifs, amyloid pore, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2021.619496/full; https://doaj.org/toc/1662-5099

URL الوصول: https://doaj.org/article/503d9970a8db4682825636f85eb5c465

المؤلفون: Beata Bugara, Małgorzata Durbas, Maja Kudrycka, Agata Malinowska, Irena Horwacik, Hanna Rokita

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, GD2 ganglioside-binding antibody, human neuroblastoma cells, PHLDA1 silencing, mass spectrometry, AUTS2

Relation: https://figshare.com/articles/dataset/DataSheet2_Silencing_of_the_PHLDA1_leads_to_global_proteome_changes_and_differentiation_pathways_of_human_neuroblastoma_cells_zip/25325410

الاتاحة: https://doi.org/10.3389/fphar.2024.1351536.s002
https://figshare.com/articles/dataset/DataSheet2_Silencing_of_the_PHLDA1_leads_to_global_proteome_changes_and_differentiation_pathways_of_human_neuroblastoma_cells_zip/25325410

المؤلفون: Beata Bugara, Małgorzata Durbas, Maja Kudrycka, Agata Malinowska, Irena Horwacik, Hanna Rokita

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, GD2 ganglioside-binding antibody, human neuroblastoma cells, PHLDA1 silencing, mass spectrometry, AUTS2

Relation: https://figshare.com/articles/dataset/Table3_Silencing_of_the_PHLDA1_leads_to_global_proteome_changes_and_differentiation_pathways_of_human_neuroblastoma_cells_XLSX/25325419

الاتاحة: https://doi.org/10.3389/fphar.2024.1351536.s005
https://figshare.com/articles/dataset/Table3_Silencing_of_the_PHLDA1_leads_to_global_proteome_changes_and_differentiation_pathways_of_human_neuroblastoma_cells_XLSX/25325419

المؤلفون: Fantini, Jacques, Scala, Coralie, Chahinian, Henri, Yahi, Nouara

المساهمون: Unité de Neurobiologie des canaux Ioniques et de la Synapse (UNIS - Inserm U1072), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0924-8579 ; International Journal of Antimicrobial Agents ; https://amu.hal.science/hal-03139161 ; International Journal of Antimicrobial Agents, 2020, 56 (2), pp.106020. ⟨10.1016/j.ijantimicag.2020.106020⟩.

مصطلحات موضوعية: coronavirus, pandemic, SARS-CoV-2, ganglioside, spike, chloroquine ACE-2, angiotensin converting enzyme-2, CLQ, chloroquine, CLQ-OH, hydroxychloroquine, COVID-19, coronavirus disease 19, GBD, ganglioside binding domain, NTD, N-terminal domain, RBD, receptor binding domain, SARS-CoV, severe acute respiratory syndrome coronavirus, SARS-coronavirus-2, [SDV]Life Sciences [q-bio]

Relation: hal-03139161; https://amu.hal.science/hal-03139161; https://amu.hal.science/hal-03139161/document; https://amu.hal.science/hal-03139161/file/Int%20J%20Antimicrob%20Agents%202020%20May%2055%285%29%20105960.pdf

الاتاحة: https://amu.hal.science/hal-03139161
https://amu.hal.science/hal-03139161/document
https://amu.hal.science/hal-03139161/file/Int%20J%20Antimicrob%20Agents%202020%20May%2055%285%29%20105960.pdf
https://doi.org/10.1016/j.ijantimicag.2020.106020

المؤلفون: Ron S. Broide, Birgitte S. Jacky, Amy Brideau-Andersen, Catherine Rheaume, David M. Jameson, Nicholas G. James, Bethany J. Sanstrum, Shiazah Z. Malik

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Cell biology, Molecular biology, media_common.quotation_subject, Science, Neurotoxins, Nerve Tissue Proteins, Receptors, Cell Surface, medicine.disease_cause, Serogroup, Transfection, PC12 Cells, Article, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Cell surface receptor, Ganglioside binding, Gangliosides, medicine, Clostridium botulinum, Neurotoxin, Animals, Botulinum Toxins, Type A, Internalization, Receptor, media_common, Neurons, Multidisciplinary, Binding Sites, Membrane Glycoproteins, Chemistry, Cell Membrane, Receptors, Fibroblast Growth Factor, Rats, ErbB Receptors, 030104 developmental biology, Fibroblast growth factor receptor, Medicine, Dimerization, 030217 neurology & neurosurgery, Binding domain, Protein Binding, Signal Transduction, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d4a9eb2a4748f04d9486588f007e80
https://doaj.org/article/b42c13adfc0c41cca508116cf7c6999f

المؤلفون: K. Ravi Acharya, Kyle S. Gregory, Sai Man Liu

المصدر: FEBS Open Bio
FEBS Open Bio, Vol 10, Iss 3, Pp 298-305 (2020)

مصطلحات موضوعية: 0301 basic medicine, Co-receptor, Botulinum Toxins, ganglioside binding, cell binding domain, Immunoglobulin light chain, medicine.disease_cause, Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Protein Domains, Ganglioside binding, Gangliosides, medicine, Humans, protein structure, Botulinum Toxins, Type A, Receptor, crystallography, lcsh:QH301-705.5, Research Articles, Neurons, Ganglioside, Binding Sites, Chemistry, Hydrogen bond, Toxin, Cell Membrane, botulinum neurotoxin, 030104 developmental biology, lcsh:Biology (General), 030220 oncology & carcinogenesis, Biophysics, Carrier Proteins, Research Article, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2cc402b96998c7bbc0608ec0135316f
http://europepmc.org/articles/PMC7050238

المؤلفون: P. M. Mitrasinovic

المصدر: Revue Roumaine de Chimie. 65:1099-1109

مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, Biochemistry, Chemistry, Ganglioside binding, In silico, General Chemistry, Protein engineering, Glycoprotein, Lipid raft, Transmembrane protein, Sialic acid, Amino acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::64cb3c91ad1bce2e1ae8622c8b3e3fc0
https://doi.org/10.33224/rrch.2020.65.12.05

المؤلفون: Kyle S. Gregory, Otsile O. Mojanaga, Sai Man Liu, K. Ravi Acharya

المصدر: Toxins; Volume 14; Issue 2; Pages: 129

مصطلحات موضوعية: Neurons, Molecular Structure, Health, Toxicology and Mutagenesis, Gangliosides, Neuromuscular Junction, Humans, Botulism, botulinum neurotoxin, crystal structure, cell binding domain, subtypes A4 and A5, ganglioside binding, Botulinum Toxins, Type A, Toxicology, Carrier Proteins, Crystallography, X-Ray

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6842506673f314c704dd74a0d2e5d436
https://pubmed.ncbi.nlm.nih.gov/35202156

المؤلفون: Jonathan R. Davies, Geoffrey Masuyer, Pål Stenmark

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 8315, p 8315 (2021)
International journal of molecular sciences 22(15), 8315 (1-12) (2021). doi:10.3390/ijms22158315

مصطلحات موضوعية: Botulinum Toxins, Protein Conformation, QH301-705.5, receptor binding, Receptors, Cell Surface, BoNT/E, medicine.disease_cause, Crystallography, X-Ray, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, 0302 clinical medicine, Ganglioside binding, medicine, Clostridium botulinum, Humans, Botulism, Amino Acid Sequence, Physical and Theoretical Chemistry, Biology (General), Receptor, Molecular Biology, QD1-999, Spectroscopy, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, glycan binding, Ganglioside, Binding Sites, Sequence Homology, Amino Acid, Chemistry, Organic Chemistry, botulinum neurotoxin, General Medicine, Oligosaccharide, medicine.disease, gangliosides, Computer Science Applications, Biochemistry, ddc:540, Cholinergic, 030217 neurology & neurosurgery, Binding domain, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdde7eb54e54a3c2f4b7c1d2229d948

المؤلفون: Hiraiwa, Masao, Soeda, Shinji, Kishimoto, Yasuo, O'Brien, John S.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1992 Dec 01. 89(23), 11254-11258.

URL الوصول: https://www.jstor.org/stable/2360685

المؤلفون: Jacques Fantini, Nouara Yahi, Henri Chahinian

المساهمون: Unité de Neurobiologie des canaux Ioniques et de la Synapse (UNIS - Inserm U1072), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Debanne, Dominique

المصدر: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, 2020, 538, pp.132-136. ⟨10.1016/j.bbrc.2020.10.015⟩
Biochemical and Biophysical Research Communications, Elsevier, 2020, 538, pp.132-136. ⟨10.1016/j.bbrc.2020.10.015⟩

مصطلحات موضوعية: 0301 basic medicine, [SDV]Life Sciences [q-bio], Plasma protein binding, Azithromycin, medicine.disease_cause, Coronavirus Vaccine SARS-CoV-2 Ganglioside Azithromycin Hydroxychloroquine Lipid raft ACE-2, Biochemistry, Epitope, RBD, 0302 clinical medicine, Gangliosides, Neutralizing antibody, Lipid raft, Coronavirus, receptor binding domain, biology, Chemistry, SARS-CoV, 3. Good health, [SDV] Life Sciences [q-bio], NTD, 030220 oncology & carcinogenesis, Spike Glycoprotein, Coronavirus, SARS-coronavirus-2, ACE-2, angiotensin converting enzyme-2, Angiotensin-Converting Enzyme 2, COVID-19, coronavirus disease 19, Hydroxychloroquine, COVID-19 Vaccines, N-terminal domain, SARS-CoV, severe acute respiratory syndrome coronavirus, Biophysics, SARS-CoV-2, SARS-coronavirus-2, Article, 03 medical and health sciences, RBD, receptor binding domain, Protein Domains, Ganglioside binding, medicine, Humans, NTD, N-terminal domain, Binding site, coronavirus disease 19, Molecular Biology, severe acute respiratory syndrome coronavirus, Ganglioside, Binding Sites, SARS-CoV-2, COVID-19, Cell Biology, Virology, Antibodies, Neutralizing, angiotensin converting enzyme-2, 030104 developmental biology, biology.protein, Vaccine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25615fc971e306afee38dbce726634e6
http://europepmc.org/articles/PMC7547605

المؤلفون: Mitrasinovic Petar M

مصطلحات موضوعية: chemistry.chemical_classification, Mutation, Chemistry, Protein engineering, medicine.disease_cause, Transmembrane protein, Sialic acid, chemistry.chemical_compound, Biochemistry, Ganglioside binding, medicine, Glycoprotein, Lipid raft, Coronavirus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c39963abba26d182cc9cb1074eb53de
https://doi.org/10.26434/chemrxiv.12765953.v1

المؤلفون: Luciano Pirone, Annarita Del Gatto, Sonia Di Gaetano, Michele Saviano, Domenica Capasso, Laura Zaccaro, Emilia Pedone

المصدر: Frontiers in Molecular Biosciences 7 (2020). doi:10.3389/fmolb.2020.00186
info:cnr-pdr/source/autori:Pirone L.; Del Gatto A.; Di Gaetano S.; Saviano M.; Capasso D.; Zaccaro L.; Pedone E./titolo:A multi-targeting approach to fight sars-cov-2 attachment/doi:10.3389%2Ffmolb.2020.00186/rivista:Frontiers in Molecular Biosciences/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:7
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 7 (2020)

مصطلحات موضوعية: 0301 basic medicine, integrin, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Integrin, ACE2, Computational biology, spike protein, medicine.disease_cause, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Ganglioside binding, Pandemic, medicine, Molecular Biosciences, lcsh:QH301-705.5, Molecular Biology, Integrin binding, Galectin, Coronavirus, Multi targeting, galectin, ganglioside, biology, multi targets against SARS-Cov2, 030104 developmental biology, lcsh:Biology (General), 030220 oncology & carcinogenesis, Perspective, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b3acf2a943ea993e3d5062a538ef0
https://doi.org/10.3389/fmolb.2020.00186

المؤلفون: Katja Venko (10122650), Marjana Novič (158377), Veronika Stoka (5523410), Eva Žerovnik (602005)

مصطلحات موضوعية: Molecular Biology, Neuroscience, Structural Biology, Central Nervous System, Molecular Evolution, Molecular Medicine, amyloid-forming proteins, amyloidogenic regions, transmembrane regions, amino-acid sequence predictors, cholesterol and ganglioside binding motifs, amyloid pore

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Prediction_of_Transmembrane_Regions_Cholesterol_and_Ganglioside_Binding_Sites_in_Amyloid-Forming_Proteins_Indicate_Potential_for_Amyloid_Pore_Formation_pdf/13844972

الاتاحة: https://doi.org/10.3389/fnmol.2021.619496.s001