المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/Frequency_of_LANA_ring-like_structures_in_cells_expressing_lytic_proteins_K8_and_ORF45_/13618702

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s003

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/Dose_titration_and_time_course_for_treatment_and_recovery_with_1_6-Hexanediol_/13618696

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s001

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/PML-NBs_are_resistant_to_LLPS_disruptors_/13618699

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s002

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/Rare_colocalization_of_K8_with_LANA_rings_/13618705

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s004

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/media/Untreated_iSLK_DNA_green_LANA_red_63X6Xpos01_3Drotation_Cell_/13618708

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s005

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/media/Untreated_iSLK_DNA_green_LANA_red_63X6Xpos01_3Drotation_Crop_/13618711

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s006

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/media/DOXY_DNA_green_DAXX_red_63X6Xpos03_3Drotation_Cell_/13618726

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s011

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/media/Untreated_iSLK_DNA_green_DAXX_red_Ctr_D515_Pos04_3Drotation_Cell_/13618714

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s007

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/LLPS_disrupting_agent_effects_on_KSHV_chromosome_conformation_/13618741

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g004

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/media/Untreated_iSLK_DNA_green_DAXX_red_Ctr_D515_Pos04_3Drotation_Crop_/13618717

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s008

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/media/DOXY_DNA_green_Lana_red_63X6Xpos06_3Drotation_Cell_/13618720

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s009

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/media/DOXY_DNA_green_Lana_red_63X6Xpos06_3Drotation_Crop_/13618723

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s010

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/media/DOXY_DNA_green_DAXX_red_63X6Xpos03_3Drotation_Crop_/13618729

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.s012

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/LLPS_disrupting_agent_effects_on_KSHV_transcription_and_LANA_binding_/13618738

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g003

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/LLPS_disrupting_agent_effects_on_DAXX_and_ATRX_foci_/13618735

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g002

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/Dynamic_changes_in_LANA-NB_morphology_after_lytic_induction_/13618744

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g005

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/Redistribution_of_DAXX_from_LANA-NB_during_lytic_induction_/13618747

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g006

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/Model_of_LLPS-driven_LANA-NB_formation_/13618756

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g009

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/Effects_of_shDAXX_depletion_on_KSHV_transcripts_epigenetics_and_LANA-NBs_/13618753

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g008

المؤلفون: Olga Vladimirova (6265013), Alessandra De Leo (3685876), Zhong Deng (56110), Andreas Wiedmer (56111), James Hayden (222052), Paul M. Lieberman (9167583)

مصطلحات موضوعية: Biochemistry, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, KSHV genome dynamics, reactivation Liquid-liquid phase se., KSHV DNA, Phase separation, PML foci, LLPS disruption, DAXX colocalizes, DAXX redistribution, LANA-dependent KSHV chromosome conf., form LANA-associated replication co., Latency-Associated Nuclear Antigen, LANA-NB formation, lytic reactivation, KSHV genome conformation, KSHV lytic reactivation, LANA-associated lytic replication c.

Relation: https://figshare.com/articles/figure/Sensitivity_of_lytic_induced_LANA_ring-like_structures_to_LLPS_/13618750

الاتاحة: https://doi.org/10.1371/journal.ppat.1009231.g007