المؤلفون: Giuseppe Campiani (1714282), Caterina Cavella (7852640), Jeremy D. Osko (5262062), Margherita Brindisi (1714312), Nicola Relitti (5143451), Simone Brogi (715714), A. Prasanth Saraswati (9460123), Stefano Federico (9460126), Giulia Chemi (4887832), Samuele Maramai (1871650), Gabriele Carullo (6384479), Benedikt Jaeger (11113215), Alfonso Carleo (11113218), Rosaria Benedetti (1859671), Federica Sarno (3232011), Stefania Lamponi (140398), Paola Rottoli (8467725), Elena Bargagli (8467728), Carlo Bertucci (1703254), Daniele Tedesco (1703248), Daniel Herp (3930101), Johanna Senger (1463518), Giovina Ruberti (687850), Fulvio Saccoccia (2400835), Simona Saponara (1714297), Beatrice Gorelli (1714279), Massimo Valoti (1960363), Breándan Kennedy (11113221), Husvinee Sundaramurthi (9302249), Stefania Butini (1714288), Manfred Jung (26925), Katy M. Roach (7630040), Lucia Altucci (96038), Peter Bradding (60398), David W. Christianson (1294293), Sandra Gemma (1714309), Antje Prasse (354621)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, HDAC 6, IPF lung tissues, lung model, HDAC 6 overexpression, Biological Evaluation, first-in-class molecules, HDAC activities, vivo toxicity, Structural analysis, fibrotic sphere formation, novel h HDAC 6 inhibitors, binding mode, immunohistochemistry studies, Idiopathic Pulmonary Fibrosis, IPF phenotype, analogue 6 h, Potent Inhibitors Idiopathic, lung disease, h HDAC 1, TGF -β1-dependent fibrogenesis, cell viability

Relation: https://figshare.com/articles/journal_contribution/Harnessing_the_Role_of_HDAC6_in_Idiopathic_Pulmonary_Fibrosis_Design_Synthesis_Structural_Analysis_and_Biological_Evaluation_of_Potent_Inhibitors/14959785

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00184.s001

المؤلفون: Giuseppe Campiani (1714282), Caterina Cavella (7852640), Jeremy D. Osko (5262062), Margherita Brindisi (1714312), Nicola Relitti (5143451), Simone Brogi (715714), A. Prasanth Saraswati (9460123), Stefano Federico (9460126), Giulia Chemi (4887832), Samuele Maramai (1871650), Gabriele Carullo (6384479), Benedikt Jaeger (11113215), Alfonso Carleo (11113218), Rosaria Benedetti (1859671), Federica Sarno (3232011), Stefania Lamponi (140398), Paola Rottoli (8467725), Elena Bargagli (8467728), Carlo Bertucci (1703254), Daniele Tedesco (1703248), Daniel Herp (3930101), Johanna Senger (1463518), Giovina Ruberti (687850), Fulvio Saccoccia (2400835), Simona Saponara (1714297), Beatrice Gorelli (1714279), Massimo Valoti (1960363), Breándan Kennedy (11113221), Husvinee Sundaramurthi (9302249), Stefania Butini (1714288), Manfred Jung (26925), Katy M. Roach (7630040), Lucia Altucci (96038), Peter Bradding (60398), David W. Christianson (1294293), Sandra Gemma (1714309), Antje Prasse (354621)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, HDAC 6, IPF lung tissues, lung model, HDAC 6 overexpression, Biological Evaluation, first-in-class molecules, HDAC activities, vivo toxicity, Structural analysis, fibrotic sphere formation, novel h HDAC 6 inhibitors, binding mode, immunohistochemistry studies, Idiopathic Pulmonary Fibrosis, IPF phenotype, analogue 6 h, Potent Inhibitors Idiopathic, lung disease, h HDAC 1, TGF -β1-dependent fibrogenesis, cell viability

Relation: https://figshare.com/articles/dataset/Harnessing_the_Role_of_HDAC6_in_Idiopathic_Pulmonary_Fibrosis_Design_Synthesis_Structural_Analysis_and_Biological_Evaluation_of_Potent_Inhibitors/14959788

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00184.s002

المؤلفون: Giuseppe Campiani (1714282), Caterina Cavella (7852640), Jeremy D. Osko (5262062), Margherita Brindisi (1714312), Nicola Relitti (5143451), Simone Brogi (715714), A. Prasanth Saraswati (9460123), Stefano Federico (9460126), Giulia Chemi (4887832), Samuele Maramai (1871650), Gabriele Carullo (6384479), Benedikt Jaeger (11113215), Alfonso Carleo (11113218), Rosaria Benedetti (1859671), Federica Sarno (3232011), Stefania Lamponi (140398), Paola Rottoli (8467725), Elena Bargagli (8467728), Carlo Bertucci (1703254), Daniele Tedesco (1703248), Daniel Herp (3930101), Johanna Senger (1463518), Giovina Ruberti (687850), Fulvio Saccoccia (2400835), Simona Saponara (1714297), Beatrice Gorelli (1714279), Massimo Valoti (1960363), Breándan Kennedy (11113221), Husvinee Sundaramurthi (9302249), Stefania Butini (1714288), Manfred Jung (26925), Katy M. Roach (7630040), Lucia Altucci (96038), Peter Bradding (60398), David W. Christianson (1294293), Sandra Gemma (1714309), Antje Prasse (354621)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, HDAC 6, IPF lung tissues, lung model, HDAC 6 overexpression, Biological Evaluation, first-in-class molecules, HDAC activities, vivo toxicity, Structural analysis, fibrotic sphere formation, novel h HDAC 6 inhibitors, binding mode, immunohistochemistry studies, Idiopathic Pulmonary Fibrosis, IPF phenotype, analogue 6 h, Potent Inhibitors Idiopathic, lung disease, h HDAC 1, TGF -β1-dependent fibrogenesis, cell viability

Relation: https://figshare.com/articles/dataset/Harnessing_the_Role_of_HDAC6_in_Idiopathic_Pulmonary_Fibrosis_Design_Synthesis_Structural_Analysis_and_Biological_Evaluation_of_Potent_Inhibitors/14959794

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00184.s004

المؤلفون: Giuseppe Campiani (1714282), Caterina Cavella (7852640), Jeremy D. Osko (5262062), Margherita Brindisi (1714312), Nicola Relitti (5143451), Simone Brogi (715714), A. Prasanth Saraswati (9460123), Stefano Federico (9460126), Giulia Chemi (4887832), Samuele Maramai (1871650), Gabriele Carullo (6384479), Benedikt Jaeger (11113215), Alfonso Carleo (11113218), Rosaria Benedetti (1859671), Federica Sarno (3232011), Stefania Lamponi (140398), Paola Rottoli (8467725), Elena Bargagli (8467728), Carlo Bertucci (1703254), Daniele Tedesco (1703248), Daniel Herp (3930101), Johanna Senger (1463518), Giovina Ruberti (687850), Fulvio Saccoccia (2400835), Simona Saponara (1714297), Beatrice Gorelli (1714279), Massimo Valoti (1960363), Breándan Kennedy (11113221), Husvinee Sundaramurthi (9302249), Stefania Butini (1714288), Manfred Jung (26925), Katy M. Roach (7630040), Lucia Altucci (96038), Peter Bradding (60398), David W. Christianson (1294293), Sandra Gemma (1714309), Antje Prasse (354621)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, HDAC 6, IPF lung tissues, lung model, HDAC 6 overexpression, Biological Evaluation, first-in-class molecules, HDAC activities, vivo toxicity, Structural analysis, fibrotic sphere formation, novel h HDAC 6 inhibitors, binding mode, immunohistochemistry studies, Idiopathic Pulmonary Fibrosis, IPF phenotype, analogue 6 h, Potent Inhibitors Idiopathic, lung disease, h HDAC 1, TGF -β1-dependent fibrogenesis, cell viability

Relation: https://figshare.com/articles/dataset/Harnessing_the_Role_of_HDAC6_in_Idiopathic_Pulmonary_Fibrosis_Design_Synthesis_Structural_Analysis_and_Biological_Evaluation_of_Potent_Inhibitors/14959791

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00184.s003