المؤلفون: Curtis, Brian, Ashbrook, Liza, Young, Terry, Finn, Laurel, Ptáček, Louis, Jones, Christopher, Fu, Ying-hui

المصدر: Sleep. 42(10)

مصطلحات موضوعية: advanced sleep phase, advanced sleep-wake phase disorder, circadian, familial advanced sleep phase, prevalence, Adult, Circadian Rhythm, Female, Humans, Male, Middle Aged, Pedigree, Prevalence, Prospective Studies, Sleep, Sleep Disorders, Circadian Rhythm, Surveys and Questionnaires, Wakefulness

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9c859127

المؤلفون: Kurien, Philip, Hsu, Pei-Ken, Leon, Jacy, Wu, David, McMahon, Thomas, Shi, Guangsen, Xu, Ying, Lipzen, Anna, Pennacchio, Len A, Jones, Christopher R, Fu, Ying-Hui, Ptáček, Louis J

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(24)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Genetics, Sleep Research, Basic Behavioral and Social Science, Neurosciences, Behavioral and Social Science, 2.1 Biological and endogenous factors, Generic health relevance, Good Health and Well Being, Animals, Cell Cycle Proteins, Cell Line, Circadian Clocks, Circadian Rhythm, Fibroblasts, HEK293 Cells, Humans, Intracellular Signaling Peptides and Proteins, Light, Male, Mice, Mice, Inbred C57BL, Mutation, Sleep, TIMELESS, human genetics, mammalian circadian clock regulation, familial advanced sleep phase

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7z4576c9
https://escholarship.org/content/qt7z4576c9/qt7z4576c9.pdf

المؤلفون: Hirano, Arisa, Shi, Guangsen, Jones, Christopher R, Lipzen, Anna, Pennacchio, Len A, Xu, Ying, Hallows, William C, McMahon, Thomas, Yamazaki, Maya, Ptáček, Louis J, Fu, Ying-Hui

المصدر: eLife. 5(AUGUST)

مصطلحات موضوعية: Animals, Humans, Mice, Sleep Disorders, Circadian Rhythm, Alanine, Threonine, F-Box Proteins, Amino Acid Substitution, Protein Conformation, Mutation, Missense, Mutant Proteins, Ubiquitination, Cryptochromes, Proteolysis, FBXL3, Familial Advanced Sleep Phase, circadian clock, circadian rhythm, cryptochrome2, human, human biology, medicine, mouse, neuroscience, Sleep Disorders, Circadian Rhythm, Mutation, Missense, Genetics, Clinical Research, Sleep Research, Neurosciences, Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9p81w5sk

المؤلفون: Zhang, Luoying, Hirano, Arisa, Hsu, Pei-Ken, Jones, Christopher, Sakai, Noriaki, Okuro, Masashi, McMahon, Thomas, Yamazaki, Maya, Xu, Ying, Saigoh, Noriko, Saigoh, Kazumasa, Lin, Shu-Ting, Nishino, Seiji, Ptáček, Louis, Fu, Ying-hui, Kaasik, Krista

المصدر: Proceedings of the National Academy of Sciences of USA. 113(11)

مصطلحات موضوعية: PER3, circadian clock, circadian rhythms, familial advanced sleep phase, seasonal affective disorder, Affect, Aged, Amino Acid Sequence, Animals, Circadian Clocks, Female, Humans, Male, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Middle Aged, Molecular Sequence Data, Period Circadian Proteins, Photoperiod, Protein Stability, Seasonal Affective Disorder, Sleep Disorders, Circadian Rhythm

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0pq2q375

المؤلفون: Hsu, Pei-Ken, Ptáček, Louis J, Fu, Ying-Hui

مصطلحات موضوعية: Biological Sciences, Genetics, Behavioral and Social Science, Clinical Research, Human Genome, Basic Behavioral and Social Science, Sleep Research, 2.1 Biological and endogenous factors, Aetiology, Animals, Behavior, Humans, Models, Animal, Phenotype, Sleep, Active phase, Circadian period, Circadian rhythms, Copy-number variation, Electroencephalography, Familial advanced sleep phase, Familial natural short sleep, Linkage analysis, Mouse models, Rebound sleep, Rest phase, Sequencing, Single nucleotide polymorphism, Sleep deprivation, Sleep homeostasis, δ Power, Biochemistry and Cell Biology, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2f21d6wb

المؤلفون: Hsu, Pei-Ken, Ptáček, Louis J, Fu, Ying-Hui

مصطلحات موضوعية: Animals, Humans, Models, Animal, Behavior, Sleep, Phenotype, Active phase, Circadian period, Circadian rhythms, Copy-number variation, Electroencephalography, Familial advanced sleep phase, Familial natural short sleep, Linkage analysis, Mouse models, Rebound sleep, Rest phase, Sequencing, Single nucleotide polymorphism, Sleep deprivation, Sleep homeostasis, δ Power, Models, Animal, Basic Behavioral and Social Science, Sleep Research, Human Genome, Behavioral and Social Science, Clinical Research, Genetics, 2.1 Biological and endogenous factors, Biochemistry & Molecular Biology, Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2f21d6wb

المؤلفون: Chong, SY Christin, Ptáček, Louis J, Fu, Ying-Hui

المصدر: Trends in Genetics. 28(12)

مصطلحات موضوعية: Biological Sciences, Genetics, Sleep Research, Behavioral and Social Science, Basic Behavioral and Social Science, Neurosciences, Animals, Cell Nucleus, Cytoplasm, Drosophila Proteins, Epigenesis, Genetic, Gene Expression Regulation, Humans, Mutation, Period Circadian Proteins, Phosphorylation, Protein Processing, Post-Translational, Protein Transport, Sleep Disorders, Circadian Rhythm, Wakefulness, circadian rhythm, post-translational regulation, familial advanced sleep phase disorder, phosphorylation, period homolog 2, casein kinase 1 delta, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/34f8999z

المؤلفون: Jakob Halekotte, Lydia Witt, Chiara Ianes, Marc Krüger, Mike Bührmann, Daniel Rauh, Christian Pichlo, Elena Brunstein, Andreas Luxenburger, Ulrich Baumann, Uwe Knippschild, Joachim Bischof, Christian Peifer

المصدر: Molecules; Volume 22; Issue 4; Pages: 522

مصطلحات موضوعية: protein kinase CK1, formerly known as casein kinase 1, p38 MAPK, kinase inhibitors, 4,5-diaryl-imidazoles, Alzheimer’s disease, amyotrophic lateral sclerosis, familial advanced sleep phase syndrome, cancer

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules22040522

الاتاحة: https://doi.org/10.3390/molecules22040522

المؤلفون: Arisa Hirano, Guangsen Shi, Christopher R Jones, Anna Lipzen, Len A Pennacchio, Ying Xu, William C Hallows, Thomas McMahon, Maya Yamazaki, Louis J Ptáček, Ying-Hui Fu

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: circadian clock, cryptochrome2, circadian rhythm, FBXL3, Familial Advanced Sleep Phase, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/16695; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/136bb08d5052403ab88a6847a7402a92

المؤلفون: Brian J. Curtis, Christopher R. Jones, Terry Young, Louis J. Ptáček, Ying-Hui Fu, Liza H. Ashbrook, Laurel Finn

المصدر: Sleep, vol 42, iss 10
Sleep

مصطلحات موضوعية: Adult, Male, Pediatrics, medicine.medical_specialty, Evening, prevalence, Population, Medical and Health Sciences, 03 medical and health sciences, 0302 clinical medicine, Clinical Research, Sleep Disorders, Circadian Rhythm, advanced sleep-wake phase disorder, Surveys and Questionnaires, Physiology (medical), Behavioral and Social Science, Prevalence, medicine, Humans, Prospective Studies, Circadian rhythm, Wakefulness, Family history, education, familial advanced sleep phase, 030304 developmental biology, Morning, 0303 health sciences, education.field_of_study, Neurology & Neurosurgery, Circadian Rhythms and Circadian Disorders, Psychology and Cognitive Sciences, Neurosciences, Advanced sleep phase disorder, Chronotype, Middle Aged, Biological Sciences, medicine.disease, Sleep in non-human animals, Circadian Rhythm, Pedigree, circadian, Female, Neurology (clinical), Sleep Research, Sleep Disorders, Sleep, advanced sleep phase, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0185d8c857ac54aa43ef3f10bf97971
https://doi.org/10.1093/sleep/zsz148

المؤلفون: Christopher R. Jones, Ying Xu, Philip A. Kurien, Ying-Hui Fu, Anna Lipzen, Thomas A. McMahon, Len A. Pennacchio, Pei Ken Hsu, Jacy Leon, Louis J. Ptáček, Guangsen Shi, David Wu

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 24

مصطلحات موضوعية: 0301 basic medicine, Male, Light, Timeless, Circadian clock, Mutant, human genetics, Cell Cycle Proteins, Biology, Inbred C57BL, Basic Behavioral and Social Science, Cell Line, 03 medical and health sciences, Mice, 0302 clinical medicine, Circadian Clocks, Behavioral and Social Science, MD Multidisciplinary, medicine, CRISPR, Animals, Humans, Circadian rhythm, Gene, familial advanced sleep phase, TIMELESS, Multidisciplinary, Advanced sleep phase disorder, Intracellular Signaling Peptides and Proteins, Neurosciences, Fibroblasts, medicine.disease, Cell biology, Circadian Rhythm, Mice, Inbred C57BL, Good Health and Well Being, 030104 developmental biology, medicine.anatomical_structure, HEK293 Cells, PNAS Plus, Mutation, mammalian circadian clock regulation, Sleep, Sleep Research, Nucleus, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b1a61b17ac091ca167c12bd772abf8
https://escholarship.org/uc/item/7z4576c9

المؤلفون: Daniela Pietrobon, Kevin C. Brennan

المصدر: The Journal of Headache and Pain
The Journal of Headache and Pain, Vol 20, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: medicine.medical_specialty, Neurology, Familial advanced sleep phase syndrome, Migraine Disorders, lcsh:Medicine, Review Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Genetic model, medicine, Animals, Humans, Genetic mouse model, 030212 general & internal medicine, Synaptic transmission, Familial hemiplegic migraine, Migraine, Cerebral Cortex, Neurons, business.industry, lcsh:R, Glutamate receptor, General Medicine, medicine.disease, Disease Models, Animal, Anesthesiology and Pain Medicine, medicine.anatomical_structure, Trigeminovascular pain pathway, Cerebral cortex, Cortical spreading depression, Glutamate, Neurology (clinical), business, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da2243389fe15d5e05357366c09bd69
http://hdl.handle.net/11577/3310169

المؤلفون: John Y.L. Chiang, Jessica M. Ferrell

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 2, Pp 113-122 (2015)

مصطلحات موضوعية: CRY, cryptochrome, FEO, food entrainable oscillator, TGR5, G protein-coupled bile acid receptor, Disease, Type 2 diabetes, Review, Shift work, SHP, small heterodimer partner, NAD+, nicotinamide adenine dinucleotide, LDL, low-density lipoprotein, CYPs, cytochrome P450 enzymes, HLF, hepatic leukemia factor, BMAL1, brain and muscle ARNT-like 1, HIP, hypoxia inducing protein, General Pharmacology, Toxicology and Pharmaceutics, RORα, retinoid-related orphan receptor α, FOXO3, forkhead box O3, RHT, retinohypothalamic tract, Circadian rhythm, CLOCK, circadian locomotor output cycles kaput, GLUT2, glucose transporter 2, Sleep in non-human animals, Metabolic syndrome, RORE, ROR-response element, Liver, CAR, constitutive androstane receptor, E-box, enhance box, medicine.medical_specialty, SIRT1, sirtuin 1, DBP, D-site binding protein, PER, period, TEF, thyrotroph embryonic factor, ARC, arcuate nucleus, Internal medicine, LRH1, liver receptor homolog 1, medicine, FXR, farnesoid-X receptor, SCN, suprachiasmatic nucleus, business.industry, lcsh:RM1-950, HDAC3, histone deacetylase 3, EMT, emergency medical technician, FASPS, familial advanced sleep-phase syndrome, medicine.disease, CYP7A1, cholesterol 7α-hydroxylase, Obesity, lcsh:Therapeutics. Pharmacology, Endocrinology, TTFL, transcriptional translational feedback loop, FAA, food anticipatory activity, business, Dyslipidemia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8694c3a420c6177ab77df19b950020b0
http://europepmc.org/articles/PMC4629216

المؤلفون: Daniel Rauh, Christian Peifer, Joachim Bischof, Mike Bührmann, Christian Pichlo, Andreas Luxenburger, Marc Krüger, Ulrich Baumann, Chiara Ianes, Jakob Halekotte, Lydia Witt, Uwe Knippschild, Elena Brunstein

المصدر: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 4; Pages: 522

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, amyotrophic lateral sclerosis, Pharmaceutical Science, Crystallography, X-Ray, Analytical Chemistry, Pathogenesis, Mitogen-Activated Protein Kinase 14, 0302 clinical medicine, Adenosine Triphosphate, 4,5-diaryl-imidazoles, Drug Discovery, kinase inhibitors, Phylogeny, Kinase, Imidazoles, Alzheimer's disease, Small molecule, Biochemistry, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Casein Kinase Idelta, Molecular Medicine, Casein kinase 1, Alzheimer’s disease, Gene isoform, familial advanced sleep phase syndrome, Biology, p38 MAPK, Article, 03 medical and health sciences, Inhibitory Concentration 50, Cell Line, Tumor, medicine, Humans, cancer, Physical and Theoretical Chemistry, Protein kinase A, IC50, Protein Kinase Inhibitors, protein kinase CK1, formerly known as casein kinase 1, Organic Chemistry, Cancer, medicine.disease, 030104 developmental biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8a11cd817793c3b2a0a29e7eed04c9
https://pubmed.ncbi.nlm.nih.gov/28338621

المؤلفون: Angshuman Bagchi, Ananya Ali

المصدر: Advances in Intelligent Systems and Computing ISBN: 9789811020346

مصطلحات موضوعية: Genetics, CLOCK, Circadian rhythm sleep disorder, Familial advanced sleep phase syndrome, Casein Kinase I, Mutant, medicine, Wild type, Advanced sleep phase disorder, Circadian rhythm, Biology, medicine.disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf54b8dd19bfe5906c790f197a1b225f
https://doi.org/10.1007/978-981-10-2035-3_1

المؤلفون: Hiroyuki Tamiya, Masahiro Akishita, Yasuyoshi Ouchi, Sumito Ogawa

المصدر: Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, endocrine system, Familial advanced sleep phase syndrome, Photoperiod, Period (gene), Circadian clock, Cell Culture Techniques, Biology, Models, Biological, Article, Gene Knockout Techniques, Mice, 03 medical and health sciences, 0302 clinical medicine, Sleep Disorders, Circadian Rhythm, Animals, Circadian rhythm, Cells, Cultured, Genetics, Multidisciplinary, Mouse Embryonic Stem Cells, Period Circadian Proteins, Circadian Rhythm, Cell biology, PER2, Light intensity, 030104 developmental biology, Mutation, NIH 3T3 Cells, Female, Locomotion, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, PER1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434f6e78d2a4e79bfb53d3f9583670e1
https://doi.org/10.1038/srep32769

المؤلفون: Maya Yamazaki, Guangsen Shi, Arisa Hirano, William C. Hallows, Louis J. Ptáček, Thomas A. McMahon, Len A. Pennacchio, Anna Lipzen, Christopher R. Jones, Ying-Hui Fu, Ying Xu

المصدر: eLife, vol 5, iss AUGUST
eLife
Hirano, A; Shi, G; Jones, CR; Lipzen, A; Pennacchio, LA; Xu, Y; et al.(2016). A cryptochrome 2 mutation yields advanced sleep phase in humans. eLife, 5(AUGUST). doi: 10.7554/eLife.16695. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9p81w5sk
eLife, Vol 5 (2016)

مصطلحات موضوعية: 0301 basic medicine, Threonine, medicine, Mouse, Protein Conformation, Circadian clock, Familial Advanced Sleep Phase, neuroscience, chemistry.chemical_compound, Mice, circadian clock, Missense mutation, Biology (General), 2. Zero hunger, Genetics, Flavin adenine dinucleotide, Alanine, General Neuroscience, Advanced sleep phase disorder, human biology, General Medicine, 3. Good health, Ubiquitin ligase, cryptochrome2, Mutation (genetic algorithm), Medicine, Sleep Research, Research Article, Human, circadian rhythm, animal structures, QH301-705.5, Science, Period (gene), Mutation, Missense, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Sleep Disorders, Circadian Rhythm, Clinical Research, Free-running sleep, Animals, Humans, human, Human Biology and Medicine, mouse, General Immunology and Microbiology, F-Box Proteins, Ubiquitination, Neurosciences, medicine.disease, Cryptochromes, 030104 developmental biology, chemistry, Amino Acid Substitution, Mutation, Proteolysis, biology.protein, Mutant Proteins, sense organs, Biochemistry and Cell Biology, Missense, Sleep Disorders, FBXL3, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d582b511663f726456ae4f64a051659f
https://escholarship.org/uc/item/9p81w5sk

المؤلفون: Narasimamurthy, R, Virshup, D.M

المساهمون: DUKE-NUS MEDICAL SCHOOL

المصدر: Unpaywall 20201031

مصطلحات موضوعية: casein kinase I, casein kinase II, PER2 protein, circadian rhythm, DNA replication, Drosophila, enzyme activity, enzyme regulation, familial advanced sleep phase, feedback system, feeding behavior, gene frequency, hormone release, mathematical model, missense mutation, Neurospora, nonhuman, oscillator, protein degradation, protein function, protein phosphorylation, protein processing, Short Survey, sleep parameters, sleep waking cycle, temperature compensation, thermoregulation

Relation: Narasimamurthy, R, Virshup, D.M (2017). Molecular mechanisms regulating temperature compensation of the circadian clock. Frontiers in Neurology 8 (APR) : 161. ScholarBank@NUS Repository. https://doi.org/10.3389/fneur.2017.00161; https://scholarbank.nus.edu.sg/handle/10635/179509

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/179509

المؤلفون: Albert Goldbeter, Jean-Christophe Leloup

المصدر: BioEssays. 30:590-600

مصطلحات موضوعية: medicine.medical_specialty, Familial advanced sleep phase syndrome, Photoperiod, Circadian clock, Cell Cycle Proteins, Biology, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Sleep Disorders, Circadian Rhythm, Internal medicine, medicine, Animals, Humans, RNA, Messenger, Circadian rhythm, Phase response curve, Jet Lag Syndrome, Mammals, Flavoproteins, Period Circadian Proteins, Bacterial circadian rhythms, Circadian Rhythm, Cryptochromes, Endocrinology, Light effects on circadian rhythm, Mutation, Entrainment (chronobiology), Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc9e460bcee27399bb3bbd2059962bb
https://doi.org/10.1002/bies.20762

المؤلفون: Louis J. Ptáček, Shu Ting Lin, Ying Xu, Luoying Zhang, Seiji Nishino, Ying-Hui Fu, Masashi Okuro, Noriko Saigoh, Noriaki Sakai, Krista Kaasik, Maya Yamazaki, Pei Ken Hsu, Kazumasa Saigoh, Thomas A. McMahon, Arisa Hirano, Christopher R. Jones

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 11

مصطلحات موضوعية: 0301 basic medicine, Male, Circadian clock, Inbred C57BL, Transgenic, Mice, 0302 clinical medicine, circadian clock, Mice, Knockout, Multidisciplinary, Depression, Protein Stability, Advanced sleep phase disorder, PER3, Seasonal Affective Disorder, Period Circadian Proteins, Middle Aged, Sleep in non-human animals, Circadian Rhythm, Mental Health, PNAS Plus, Female, Sleep Research, Psychology, medicine.medical_specialty, Period (gene), Knockout, Photoperiod, Molecular Sequence Data, Mice, Transgenic, 03 medical and health sciences, Sleep Disorders, Circadian Rhythm, Internal medicine, Circadian Clocks, Behavioral and Social Science, Genetics, medicine, Animals, Humans, Circadian rhythm, Amino Acid Sequence, familial advanced sleep phase, Aged, Neurosciences, medicine.disease, Brain Disorders, Mice, Inbred C57BL, Affect, 030104 developmental biology, Endocrinology, Mood, circadian rhythms, Sleep Disorders, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbee51bbcf83f6c6e02d48e9ef8dd5d
https://europepmc.org/articles/PMC4801303/