المؤلفون: Wei Shi (68167), Jianxin Zhang (303858), Liya Liu (6158897), Wanzhen Li (2256664), Zhi Liu (165121), Anni Ren (1528642), Jie Wang (16762), Caihong Tang (14049126), Yang Yang (45629), Dandan Xu (149923), Qianqian Huang (1409008), Yongqin Wang (515167), Caili Luo (14312769), Wei Huang (36889), Feng Tang (136667)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Space Science, Chemical Sciences not elsewhere classified, showed excellent hydrophilicity, ones conjugated onto, immunoglobulin class g, extra hydrophilic linkers, terminal sialic acid, drug complexes onto, hiding payload inside, terminal galactose, vivo <, therapeutic index, significantly enhance, optimal druggability, intact glycan, inadequate understanding, fc cavity, drug combinations, achieve better

Relation: https://figshare.com/articles/journal_contribution/Hiding_Payload_Inside_the_IgG_Fc_Cavity_Significantly_Enhances_the_Therapeutic_Index_of_Antibody_Drug_Conjugates/21799041

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01812.s001

المؤلفون: Wei Shi (68167), Jianxin Zhang (303858), Liya Liu (6158897), Wanzhen Li (2256664), Zhi Liu (165121), Anni Ren (1528642), Jie Wang (16762), Caihong Tang (14049126), Yang Yang (45629), Dandan Xu (149923), Qianqian Huang (1409008), Yongqin Wang (515167), Caili Luo (14312769), Wei Huang (36889), Feng Tang (136667)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Space Science, Chemical Sciences not elsewhere classified, showed excellent hydrophilicity, ones conjugated onto, immunoglobulin class g, extra hydrophilic linkers, terminal sialic acid, drug complexes onto, hiding payload inside, terminal galactose, vivo <, therapeutic index, significantly enhance, optimal druggability, intact glycan, inadequate understanding, fc cavity, drug combinations, achieve better

Relation: https://figshare.com/articles/dataset/Hiding_Payload_Inside_the_IgG_Fc_Cavity_Significantly_Enhances_the_Therapeutic_Index_of_Antibody_Drug_Conjugates/21799044

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01812.s002

المؤلفون: Wei Shi (68167), Jianxin Zhang (303858), Liya Liu (6158897), Wanzhen Li (2256664), Zhi Liu (165121), Anni Ren (1528642), Jie Wang (16762), Caihong Tang (14049126), Yang Yang (45629), Dandan Xu (149923), Qianqian Huang (1409008), Yongqin Wang (515167), Caili Luo (14312769), Wei Huang (36889), Feng Tang (136667)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Space Science, Chemical Sciences not elsewhere classified, showed excellent hydrophilicity, ones conjugated onto, immunoglobulin class g, extra hydrophilic linkers, terminal sialic acid, drug complexes onto, hiding payload inside, terminal galactose, vivo <, therapeutic index, significantly enhance, optimal druggability, intact glycan, inadequate understanding, fc cavity, drug combinations, achieve better

Relation: https://figshare.com/articles/dataset/Hiding_Payload_Inside_the_IgG_Fc_Cavity_Significantly_Enhances_the_Therapeutic_Index_of_Antibody_Drug_Conjugates/21799047

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01812.s003