المؤلفون: Evangelos Miliordos, Jamonica L. Moore, Segun V. Obisesan, Julian Oppelt, Ivana Ivanović-Burmazović, Christian R. Goldsmith

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Neuroscience, Cancer, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, three oxidation states, pyridinylmethyl )- 1, base reactions involving, distal hydroxyl group, coordinating hydroxyl group, primarily use calculations, active transition metal, 2 , functional group, calculations support, para <, n <, active ligand, sphere decomposition, quinoxyl radical, proton transfer, present work, many roles, hydroxybenzyl )-<, functional mimic, dihydroxybenzyl )-<, computational analysis

Relation: https://figshare.com/articles/journal_contribution/Computational_Analysis_of_the_Superoxide_Dismutase_Mimicry_Exhibited_by_a_Zinc_II_Complex_with_a_Redox-Active_Organic_Ligand/25222329

الاتاحة: https://doi.org/10.1021/acs.jpca.3c07403.s001
https://figshare.com/articles/journal_contribution/Computational_Analysis_of_the_Superoxide_Dismutase_Mimicry_Exhibited_by_a_Zinc_II_Complex_with_a_Redox-Active_Organic_Ligand/25222329

المؤلفون: Dong S., Chen Z., Wang L., Liu Y., Stagos D., Lin X., Liu M.

المصدر: Marine Drugs ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119590942&doi=10.3390%2fmd19110641&partnerID=40&md5=b25c8d9f43dc76aa778775b51c71b267

مصطلحات موضوعية: bis(2,3,6 tribromo 4,5 dihydroxybenzyl)ether, gelatinase B, phenol, unclassified drug, angiogenesis inhibitor, phenol derivative, A-549 cell line, angiogenesis, animal experiment, antiangiogenic activity, Article, cell invasion, cell migration, cell plasticity, controlled study, drug structure, embryo, human, human cell, in vitro study, in vivo study, nonhuman, tubulogenesis, umbilical vein endothelial cell, vasculogenic mimicry, zebra fish, animal, aquatic species, cell proliferation, chemistry

Relation: http://hdl.handle.net/11615/73417

الاتاحة: http://hdl.handle.net/11615/73417
https://doi.org/10.3390/md19110641

المؤلفون: Qizhi Yao, Jian-Ming Lü, Xinwen Wang, Peter H. Lin, Sarah M. Weakley, Changyi Chen, Jun Jiang

المصدر: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

مصطلحات موضوعية: antioxidant, Antioxidant, Nitric Oxide Synthase Type III, Endothelium, medicine.medical_treatment, Sus scrofa, Down-Regulation, In Vitro Techniques, Pulmonary Artery, 030204 cardiovascular system & hematology, Pharmacology, Biology, medicine.disease_cause, endothelial dysfunction, Antioxidants, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Superoxides, Enos, medicine, Animals, Humans, 030212 general & internal medicine, Endothelial dysfunction, Benzyl Alcohols, chemistry.chemical_classification, endothelial nitric oxide synthase, Reactive oxygen species, Ritonavir, Cell-Free System, Superoxide, dihydroxybenzyl alcohol, Endothelial Cells, Free Radical Scavengers, General Medicine, Glutathione, medicine.disease, biology.organism_classification, 3. Good health, Oxidative Stress, Basic Research, medicine.anatomical_structure, chemistry, Endothelium, Vascular, Oxidative stress, pulmonary artery hypertension

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a4968b5b2ec674b1c4a623cde8d6b0
https://doi.org/10.12659/msm.881926

المؤلفون: Halis Türker Balaydın, Süleyman Göksu, Abdullah Menzek, Şükrü Beydemir, Ertan Şahin, Deniz Ekinci, Hakan Söyüt

المساهمون: Bayburt University, Balaydin, Halis Türker, OMÜ

مصطلحات موضوعية: carbonic anhydrase, (2 bromo 4,5 dihydroxyphenyl)(2,5 dibromo 3,4 dihydroxyphenyl)methanone, Catechols, carbonate dehydratase II, (2 bromo 4,5 dimethoxyphenyl)(2,6 dibromo 3,4 dimethoxyphenyl)methanone, Cytosol, (2 bromo 3,4 dihydroxyphenyl)(2,3 dibromo 4,5 dihydroxyphenyl)methanone, Drug Discovery, Carbonic anhydrase inhibitor, carbonate dehydratase inhibitor, Carbonic Anhydrase Inhibitors, enzyme inhibition, Biological Agents, Carbonic anhydrase, 3,4,6 tribromo 5 (2,5 dibromo 3,4 dihydroxybenzyl)benzene 1,2 diol, biology, 5,5' methylene bis(3,4,6 tribromo benzene 1,2 diol), Molecular Structure, Chemistry, article, Stereoisomerism, General Medicine, bromination, (2 bromo 3,4 dimethoxyphenyl)(2,3 dibromo 4,5 dimethoxyphenyl)methanone, unclassified drug, Isoenzymes, Biochemistry, priority journal, bromophenol blue, (2 bromo 4,5 dihydroxyphenyl)(2,6 dibromo 3,4 dimethoxyphenyl)methanone, medicine.drug_class, Stereochemistry, Carbonic anhydrase II, (2 bromo 3,4 dimethoxyphenyl)(2 bromo 4,5 dimethoxyphenyl)methanone, Isozyme, Carbonic Anhydrase II, (2 bromo 4,5 dimethoxyphenyl)(2,5 dibromo 3,4 dimethoxyphenyl)methanone, Benzophenones, Structure-Activity Relationship, (2 bromo 3,4 dihydroxyphenyl)(2 bromo 4,5 dihydroxyphenyl)methanone, medicine, Structure–activity relationship, Humans, human, bromine derivative, Demethylation, Pharmacology, Biological Products, (2 bromo 3,4 dimethoxyphenyl)(3,4 dimethoxyphenyl)methanone, Dose-Response Relationship, Drug, Diphenylmethane, demethylation, Glaucoma, IC 50, glaucoma, Bromophenols, biology.protein, drug synthesis, diphenylmethane, Bromobenzenes

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21e243dbc8de26b380f407ccec5e054
https://aperta.ulakbim.gov.tr/record/87759

المؤلفون: Kwong, Theresa Fuk Ning, Miao, Li, Li, Xiancui, Qian, Peiyuan

مصطلحات موضوعية: Ampelomyces, Antifouling agent, Antimicrobial agent, 3-chloro-2,5-dihydroxybenzyl alcohol, 3-chloro-2,5- dihydroxybenzyl alcohol

Relation: http://repository.ust.hk/ir/Record/1783.1-46445; Marine biotechnology, v. 8, (6), November 2006, p. 634-640; https://doi.org/10.1007/s10126-005-6146-2; http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=1436-2228&rft.volume=8&rft.issue=6&rft.date=2006&rft.spage=634&rft.epage=640&rft.aulast=Kwong&rft.aufirst=Theresa+Fuk+Ning&rft.atitle=Novel+antifouling+and+antimicrobial+compound+from+a+marine-derived+fungus+Ampelomyces+sp.; http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000243193200007; http://www.scopus.com/record/display.url?eid=2-s2.0-33846224344&origin=inward

الاتاحة: http://repository.ust.hk/ir/Record/1783.1-46445
https://doi.org/10.1007/s10126-005-6146-2
http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=1436-2228&rft.volume=8&rft.issue=6&rft.date=2006&rft.spage=634&rft.epage=640&rft.aulast=Kwong&rft.aufirst=Theresa+Fuk+Ning&rft.atitle=Novel+antifouling+and+antimicrobial+compound+from+a+marine-derived+fungus+Ampelomyces+sp.
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000243193200007
http://www.scopus.com/record/display.url?eid=2-s2.0-33846224344&origin=inward

المؤلفون: Balaydiin H.T., Soyut H., Ekinci D., Göksu S., Beydemir S., Menzek A., Şahin E.

المساهمون: Bayburt University, 54882270000, 23502381000, 23027537500, 6701789599, 6603903192, 6603339039, 14009507000

مصطلحات موضوعية: Bromophenols, Carbonic anhydrase, Diphenylmethane, Enzyme inhibition, Glaucoma, (2 bromo 3,4 dihydroxyphenyl)(2 bromo 4,5 dihydroxyphenyl)methanone, (2 bromo 3,4 dihydroxyphenyl)(2,3 dibromo 4,5 dihydroxyphenyl)methanone, (2 bromo 3,4 dimethoxyphenyl)(2 bromo 4,5 dimethoxyphenyl)methanone, (2 bromo 3,4 dimethoxyphenyl)(2,3 dibromo 4,5 dimethoxyphenyl)methanone, (2 bromo 3,4 dimethoxyphenyl)(3,4 dimethoxyphenyl)methanone, (2 bromo 4,5 dihydroxyphenyl)(2,5 dibromo 3,4 dihydroxyphenyl)methanone, (2 bromo 4,5 dihydroxyphenyl)(2,6 dibromo 3,4 dimethoxyphenyl)methanone, (2 bromo 4,5 dimethoxyphenyl)(2,5 dibromo 3,4 dimethoxyphenyl)methanone, (2 bromo 4,5 dimethoxyphenyl)(2,6 dibromo 3,4 dimethoxyphenyl)methanone, 3,4,6 tribromo 5 (2,5 dibromo 3,4 dihydroxybenzyl)benzene 1,2 diol, 5,5' methylene bis(3,4,6 tribromo benzene 1,2 diol), bromine derivative, bromophenol blue, carbonate dehydratase II, carbonate dehydratase inhibitor, unclassified drug, article, bromination, cytosol, demethylation, drug synthesis, human, IC 50, priority journal, Benzophenones

Relation: Journal of Enzyme Inhibition and Medicinal Chemistry; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://dx.doi.org/10.3109/14756366.2011.574131; https://hdl.handle.net/20.500.12403/909; 27; 43; 50

الاتاحة: https://hdl.handle.net/20.500.12403/909
https://doi.org/10.3109/14756366.2011.574131

المؤلفون: 史大永, 郭书举, 范晓

المساهمون: 中国科学院海洋研究所.

مصطلحات موضوعية: Ptp1b抑制剂, 其特征在于：其以下述六种化合物中的一种或一种以上为活性成份, 六种化合物结构式如下：化学名称中文分别为：3, 6?三溴?5?[(2′?溴?3′, 4′?二羟基?6′?正丙氧基甲基?苯基)?甲基]?1, 2?苯二酚(1), 4′?二羟基?6′?异丙氧基甲基?苯基)?甲基]?1, 2?苯二酚(2), 4′?二羟基?6′?正丁氧基甲基?苯基)?甲基]?1, 2?苯二酚(3), 4′?二羟基?6′?异丁氧基甲基?苯基)?甲基]?1, 2?苯二酚(4), 4?二溴?5?[(2′?溴?6′?仲丁氧基甲基?3′, 4′?二羟基?苯基)?甲基]?1, 2?苯二酚(5), 4′?二羟基?6′?甲基?苯基)?甲基]?1, 2?苯二酚(6)。英文名称分别为：3, 6?tribromo?5?(2?bromo?3, 4?dihydroxy?6?(Propoxymethyl)Benzyl)benzene?1, 2?diol(1), 4?dihydroxy?6?(Isopropoxymethyl)Benzyl)benzene?1, 2?diol(2), 6?tribromo?5?(2?bromo?6?(Butoxymethyl)?3, 4?dihydroxybenzyl)benzene?1, 2?diol(3), 4?dihydroxy?6?(Isobutoxymethyl)Benzyl)benzene?1, 2?diol(4)

Time: 4, 3

Relation: 史大永;郭书举;范晓,PTP1B抑制剂及合成和在制备治疗2型糖尿病药物中应用,CN201010248815.3,2011; http://ir.qdio.ac.cn/handle/337002/17128

الاتاحة: http://ir.qdio.ac.cn/handle/337002/17128