المؤلفون: Rebecca M. Twidale (11553350), Philip Hinchliffe (1483897), James Spencer (554121), Adrian J. Mulholland (600107)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Ecology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, stable complex formation, significantly less stable, providing mechanistic insights, one zinc ion, enamine tautomer complexes, c6 group rotation, assist inhibitor design, >)- imine tautomer, different binding modes, hydrolyzed antibiotic complexes, model alternative tautomeric, l1 active site, identify interactions important, different hydrolyzed, tautomeric states, alternative protonation, hydrolyzed ertapenem, strong interactions, stenotrophomonas maltophilia, relative stability, quantum mechanics, protonation states

Relation: https://figshare.com/articles/journal_contribution/Crystallography_and_QM_MM_Simulations_Identify_Preferential_Binding_of_Hydrolyzed_Carbapenem_and_Penem_Antibiotics_to_the_L1_Metallo-_-Lactamase_in_the_Imine_Form/16799513

الاتاحة: https://doi.org/10.1021/acs.jcim.1c00663.s001