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1Academic Journal
المؤلفون: Yntema, Tess, Eijgenraam, Tim R., Kloosterhuis, Niels J., Havinga, Rick, Koster, Mirjam H., Hovingh, Milaine V., de Boer, Jan Freark, Koonen, Debby P. Y., Kuipers, Folkert
المساهمون: This work was funded by the Netherlands Heart Foundation to F. Kuipers and D. Koonen
المصدر: Scientific Reports ; volume 15, issue 1 ; ISSN 2045-2322
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2Academic Journal
المؤلفون: Hof, Willemien F J, de Boer, Jan Freark, Verkade, Henkjan J
المصدر: Hof , W F J , de Boer , J F & Verkade , H J 2024 , ' Emerging drugs for the treatment of progressive familial intrahepatic cholestasis : a focus on phase II and III trials ' , Expert Opinion on Emerging Drugs , vol. 29 , no. 3 , pp. 305-320 . https://doi.org/10.1080/14728214.2024.2336986
مصطلحات موضوعية: Bile acids, bile salt export pump, enterohepatic circulation, ileal bile acid transporter, PFIC
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/c0a10b91-390e-4a25-97c5-1265fa6ceb2e
https://research.rug.nl/en/publications/c0a10b91-390e-4a25-97c5-1265fa6ceb2e
https://doi.org/10.1080/14728214.2024.2336986
https://pure.rug.nl/ws/files/1173441763/Emerging_drugs_for_the_treatment_of_progressive_familial_intrahepatic_cholestasis_a_focus_on_phase_II_and_III_trials.pdf
http://www.scopus.com/inward/record.url?scp=85197505999&partnerID=8YFLogxK -
3Academic Journal
المؤلفون: Sinha, Trishla, Prins, Jelmer R., Fernandez-Pato, Asier, Kruk, Marloes, Dierikx, Thomas, de Meij, Tim, de Boer, Marjon, de Boer, Jan Freark, Scherjon, Sicco, Kurilshikov, Alexander, Zhernakova, Alexandra
المصدر: Sinha , T , Prins , J R , Fernandez-Pato , A , Kruk , M , Dierikx , T , de Meij , T , de Boer , M , de Boer , J F , Scherjon , S , Kurilshikov , A & Zhernakova , A 2024 , ' Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome ' , Cell Host Microbe , vol. 32 , no. 8 , pp. 1444-1454.e6 . https://doi.org/10.1016/j.chom.2024.07.010
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4Academic Journal
المؤلفون: Gregersen, Ida, Kong, Xiang Y., Kooijman, Sander, Foyn, Håvard, Grannes, Helene, Olsen, Maria B., Lone, Anna M., Yang, Kuan, Quiles-Jiménez, Ana, Tran, Marianne, Øgaard, Jonas, Segers, Filip M., Rashidi, Azita, Sagen, Ellen Lund, Lauritzen, Knut H., Pronk, Amanda C.M., de Boer, Jan Freark, Holven, Kirsten B., Melum, Espen, Aukrust, Pål, Taskén, Kjetil, Holm, Sverre, Rensen, Patrick C.N., Dahl, Tuva B., Halvorsen, Bente
المصدر: Gregersen , I , Kong , X Y , Kooijman , S , Foyn , H , Grannes , H , Olsen , M B , Lone , A M , Yang , K , Quiles-Jiménez , A , Tran , M , Øgaard , J , Segers , F M , Rashidi , A , Sagen , E L , Lauritzen , K H , Pronk , A C M , de Boer , J F , Holven , K B , Melum , E , Aukrust , P , Taskén , K , Holm , S , ....
مصطلحات موضوعية: Immunology, Nutrition
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/a6ee9bf6-fd48-40ce-9492-1aa1676a4376
https://research.rug.nl/en/publications/a6ee9bf6-fd48-40ce-9492-1aa1676a4376
https://doi.org/10.1016/j.isci.2024.109471
https://pure.rug.nl/ws/files/1081702832/PIIS2589004224006928.pdf
http://www.scopus.com/inward/record.url?scp=85188553973&partnerID=8YFLogxK -
5Academic Journal
المؤلفون: Heida, Andries, van Dijk, Theo, Smit, Marieke, Koehorst, Martijn, Koster, Mirjam, Kloosterhuis, Niels, Havinga, Rick, Bloks, Vincent W, Wolters, Justina C, de Bruin, Alain, Kuivenhoven, Jan Albert, de Boer, Jan Freark, Kuipers, Folkert, van de Sluis, Bart
المساهمون: Pathobiologie, Biomolecular Health Sciences
مصطلحات موضوعية: Bile acids, Cholesterol, Endosome, Ezetimibe, Intestine
وصف الملف: application/pdf
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6Academic Journal
المؤلفون: Palmiotti, Anna, Berk, Kirsten A., Koehorst, Martijn, Hovingh, Milaine V., Pranger, Alle T., van Faassen, Martijn, de Boer, Jan Freark, van der Valk, Eline S., van Rossum, Elisabeth F.C., Mulder, Monique T., Kuipers, Folkert
المصدر: Palmiotti , A , Berk , K A , Koehorst , M , Hovingh , M V , Pranger , A T , van Faassen , M , de Boer , J F , van der Valk , E S , van Rossum , E F C , Mulder , M T & Kuipers , F 2024 , ' Reversal of insulin resistance in people with obesity by lifestyle-induced weight loss does not impact the proportion of circulating 12α-hydroxylated bile acids ' , Diabetes, Obesity and Metabolism , vol. 26 , no. 9 , pp. 4019-4029 . https://doi.org/10.1111/dom.15754
مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being
وصف الملف: application/pdf
الاتاحة: https://pure.eur.nl/en/publications/c0fb2275-58e1-410f-a8ad-46e62d537595
https://doi.org/10.1111/dom.15754
https://pure.eur.nl/ws/files/161544776/Reversal_of_insulin_resistance_in_people_with_obesity_by_lifestyle-induced_weight_loss_does_not_impact_the_proportion_of_circulating_12_-hydroxylated_bile_acids.pdf
http://www.scopus.com/inward/record.url?scp=85197305267&partnerID=8YFLogxK -
7Academic Journal
المؤلفون: Ying, Zhixiong, van Eenige, Robin, Ge, Xiaoke, van Marwijk, Christy, Lambooij, Joost M, Guigas, Bruno, Giera, Martin, de Boer, Jan Freark, Coskun, Tamer, Qu, Hongchang, Wang, Yanan, Boon, Mariëtte R, Rensen, Patrick C N, Kooijman, Sander
المصدر: Ying , Z , van Eenige , R , Ge , X , van Marwijk , C , Lambooij , J M , Guigas , B , Giera , M , de Boer , J F , Coskun , T , Qu , H , Wang , Y , Boon , M R , Rensen , P C N & Kooijman , S 2023 , ' Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗3-Leiden.CETP mice ' , EBioMedicine , vol. 93 , 104684 . https://doi.org/10.1016/j.ebiom.2023.104684
مصطلحات موضوعية: Humans, Mice, Male, Animals, Non-alcoholic Fatty Liver Disease/drug therapy, Diabetes Mellitus, Type 2, Apolipoprotein E3/metabolism, Obesity/complications, Glucose, Triglycerides/metabolism, Cholesterol, Inflammation, Cholesterol Ester Transfer Proteins
وصف الملف: application/pdf
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8Academic Journal
المؤلفون: Zhou, Enchen, Ge, Xiaoke, Nakashima, Hiroyuki, Li, Rumei, van der Zande, Hendrik J. P., Liu, Cong, Li, Zhuang, Müller, Christoph, Bracher, Franz, Mohammed, Yassene, de Boer, Jan Freark, Kuipers, Folkert, Guigas, Bruno, Glass, Christopher K, Rensen, Patrick C N, Giera, Martin, Wang, Yanan
المصدر: Zhou , E , Ge , X , Nakashima , H , Li , R , van der Zande , H J P , Liu , C , Li , Z , Müller , C , Bracher , F , Mohammed , Y , de Boer , J F , Kuipers , F , Guigas , B , Glass , C K , Rensen , P C N , Giera , M & Wang , Y 2023 , ' Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation ' , EMBO Molecular Medicine , vol. 15 , ....
مصطلحات موضوعية: Mice, Humans, Animals, Non-alcoholic Fatty Liver Disease/drug therapy, Desmosterol/pharmacology, Liver, Inflammation/drug therapy, Oxidoreductases, Inbred C57BL, Nerve Tissue Proteins, Oxidoreductases Acting on CH-CH Group Donors/pharmacology
وصف الملف: application/pdf
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9Academic Journal
المؤلفون: Sjöland, Wilhelm, Wahlström, Annika, Makki, Kassem, Schöler, Marc, Molinaro, Antonio, Olsson, Lisa, Greiner, Thomas Uwe, Caesar, Robert, de Boer, Jan Freark, Kuipers, Folkert, Bäckhed, Fredrik, Marschall, Hanns-Ulrich
المصدر: Sjöland , W , Wahlström , A , Makki , K , Schöler , M , Molinaro , A , Olsson , L , Greiner , T U , Caesar , R , de Boer , J F , Kuipers , F , Bäckhed , F & Marschall , H-U 2023 , ' Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in Cyp2c70-deficient mice with a human-like bile acid composition ' , Clinical Science , vol. 137 , no. 13 , pp. 995-1011 . https://doi.org/10.1042/CS20230413
مصطلحات موضوعية: Humans, Animals, Mice, Bile Acids and Salts, Gastrointestinal Microbiome/genetics, Liver, Liver Diseases/genetics, Ursodeoxycholic Acid, Digestive System Diseases, Liver Cirrhosis
وصف الملف: application/pdf
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10Academic Journal
المؤلفون: Felzen, Antonia, Hovingh, Milaine, Havinga, Rick, Mulder, Niels, Koehorst, Martijn, van de Sluis, Bart, de Boer, Jan Freark, Kuipers, Folkert, Verkade, Henkjan
المصدر: Felzen , A , Hovingh , M , Havinga , R , Mulder , N , Koehorst , M , van de Sluis , B , de Boer , J F , Kuipers , F & Verkade , H 2023 , Characterization of a novel bile salt export pump deficiency mouse model with the p.E297g mutation . in ESPGHAN 55th Annual Meeting Abstracts . vol. 76 , Wolters Kluwer , pp. 671-672 , ESPGHAN 2023 , Vienna , Austria , 17/05/2023 . https://doi.org/10.1097/MPG.0000000000003823
وصف الملف: application/pdf
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11Academic Journal
المؤلفون: van Eenige, Robin, Ying, Zhixiong, Tramper, Naomi, Wiebing, Vera, Siraj, Zohor, de Boer, Jan Freark, Lambooij, Joost M., Guigas, Bruno, Qu, Hongchang, Coskun, Tamer, Boon, Mariëtte R., Rensen, Patrick C.N., Kooijman, Sander
المصدر: van Eenige , R , Ying , Z , Tramper , N , Wiebing , V , Siraj , Z , de Boer , J F , Lambooij , J M , Guigas , B , Qu , H , Coskun , T , Boon , M R , Rensen , P C N & Kooijman , S 2023 , ' Combined glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonism attenuates atherosclerosis severity in APOE*3-Leiden.CETP mice ' , Atherosclerosis , vol. 372 , pp. 19-31 . https://doi.org/10.1016/j.atherosclerosis.2023.03.016
مصطلحات موضوعية: Adipose tissue, Atherosclerosis, Cardiovascular disease, Glucagon-like peptide-1, Glucose-dependent insulinotropic polypeptide, Lipoprotein metabolism
وصف الملف: application/pdf
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12Academic Journal
المؤلفون: Yang, Jiufang, van Dijk, Theo H., Koehorst, Martijn, Havinga, Rick, de Boer, Jan Freark, Kuipers, Folkert, van Zutphen, Tim
المصدر: Yang , J , van Dijk , T H , Koehorst , M , Havinga , R , de Boer , J F , Kuipers , F & van Zutphen , T 2023 , ' Intestinal Farnesoid X Receptor Modulates Duodenal Surface Area but Does Not Control Glucose Absorption in Mice ' , International Journal of Molecular Sciences , vol. 24 , no. 4 , 4132 . https://doi.org/10.3390/ijms24044132
مصطلحات موضوعية: duodenum, glucose absorption, GS3972, intestinal FXR
وصف الملف: application/pdf
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13Academic Journal
المؤلفون: de Vries, Hilde D, Palmiotti, Anna, Li, Rumei, Hovingh, Milaine V, Mulder, Niels L, Koehorst, Martijn, Bloks, Vincent W, van Zutphen, Tim, Kuipers, Folkert, de Boer, Jan Freark
المصدر: de Vries , H D , Palmiotti , A , Li , R , Hovingh , M V , Mulder , N L , Koehorst , M , Bloks , V W , van Zutphen , T , Kuipers , F & de Boer , J F 2023 , ' Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acids ' , Pediatric Research , vol. 93 , no. 6 , pp. 1582–1590 . https://doi.org/10.1038/s41390-022-02303-5
وصف الملف: application/pdf
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14Academic Journal
المؤلفون: Verkade, Esther, Shen, Wenqiang, Hovingh, Milaine V, Mulder, Niels L, de Bruyn, Krisztina, Koehorst, Martijn, de Vries, Hilde D, Bloks, Vincent W, Kuipers, Folkert, de Boer, Jan Freark
المصدر: Verkade , E , Shen , W , Hovingh , M V , Mulder , N L , de Bruyn , K , Koehorst , M , de Vries , H D , Bloks , V W , Kuipers , F & de Boer , J F 2023 , ' Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition ' , Clinical Science , vol. 137 , no. 21 , pp. 1637–1650 . https://doi.org/10.1042/CS20230812
وصف الملف: application/pdf
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15Academic Journal
المؤلفون: Palmiotti, Anna, de Vries, Hilde D, Hovingh, Milaine V, Koehorst, Martijn, Mulder, Niels L, Verkade, Esther, Veentjer, Melany K, van Dijk, Theo H, Bloks, Vincent W, Havinga, Rick, Verkade, Henkjan J, de Boer, Jan Freark, Kuipers, Folkert
المصدر: Palmiotti , A , de Vries , H D , Hovingh , M V , Koehorst , M , Mulder , N L , Verkade , E , Veentjer , M K , van Dijk , T H , Bloks , V W , Havinga , R , Verkade , H J , de Boer , J F & Kuipers , F 2023 , ' Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-like Bile Acid Composition ' , Biomedicines , vol. 11 , no. 9 , 2495 . ....
وصف الملف: application/pdf
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16Academic Journal
المصدر: Expert Opinion on Emerging Drugs; Sep2024, Vol. 29 Issue 3, p305-320, 16p
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17Electronic Resource
المؤلفون: Pathobiologie, Biomolecular Health Sciences, Cell Biology, Metabolism & Cancer - Cancer, Heida, Andries, van Dijk, Theo, Smit, Marieke, Koehorst, Martijn, Koster, Mirjam, Kloosterhuis, Niels, Havinga, Rick, Bloks, Vincent W, Wolters, Justina C, de Bruin, Alain, Kuivenhoven, Jan Albert, de Boer, Jan Freark, Kuipers, Folkert, van de Sluis, Bart
URL:
https://doi.org/10.1016/j.bbalip.2023.159445 http://hdl.handle.net/1874/435006 https://dspace.library.uu.nl/handle/1874/435006 http://www.scopus.com/inward/record.url?scp=85179922796&partnerID=8YFLogxK
1388-1981
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
1869
2
1
11
159445 -
18Academic Journal
المؤلفون: Paalvast, Yared, Zhou, Enchen, Rozendaal, Yvonne J.W., Wang, Yanan, Gerding, Albert, van Dijk, Theo H., de Boer, Jan Freark, Rensen, Patrick C.N., van Dijk, Ko Willems, Kuivenhoven, Jan A., Bakker, Barbara M., van Riel, Natal A.W., Groen, Albert K.
المصدر: Paalvast , Y , Zhou , E , Rozendaal , Y J W , Wang , Y , Gerding , A , van Dijk , T H , de Boer , J F , Rensen , P C N , van Dijk , K W , Kuivenhoven , J A , Bakker , B M , van Riel , N A W & Groen , A K 2022 , ' A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding ' , Nutrients , vol. 14 , no. 22 , 4936 . https://doi.org/10.3390/nu14224936
مصطلحات موضوعية: APOE3, bile acid, CETP, cholesterol, computational modeling, energy expenditure, metabolic syndrome, triglycerides
وصف الملف: application/pdf
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19Academic Journal
المصدر: Zhang , B , Kuipers , F , de Boer , J F & Kuivenhoven , J A 2022 , ' Modulation of Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles ' , Journal of Clinical Medicine , vol. 11 , no. 1 , 4 . https://doi.org/10.3390/jcm11010004
وصف الملف: application/pdf
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20Academic Journal
المؤلفون: Li, Rumei, Hovingh, Milaine V, Koehorst, Martijn, de Blaauw, Pim, Verkade, Henkjan J, de Boer, Jan Freark, Kuipers, Folkert
المصدر: Li , R , Hovingh , M V , Koehorst , M , de Blaauw , P , Verkade , H J , de Boer , J F & Kuipers , F 2022 , ' Short-term obeticholic acid treatment does not impact cholangiopathy in Cyp2c70-deficient mice with a human-like bile acid composition ' , Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol. 1867 , no. 8 , 159163 . https://doi.org/10.1016/j.bbalip.2022.159163
مصطلحات موضوعية: FXR agonist, Liver, Hydrophobicity, Cyp8b1, Inflammation, Humanized mouse model, PRIMARY BILIARY-CIRRHOSIS, X RECEPTOR ACTIVATION, CHOLESTEROL, FXR, MULTICENTER, CELLS
وصف الملف: application/pdf