نتائج البحث - "db/db mouse model"

1

Academic Journal

The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice

المؤلفون: Yue Gu, Elisa Avolio, Valeria V Alvino, Anita C Thomas, Andrew Herman, Poppy J Miller, Niall Sullivan, Ashton Faulkner, Paolo Madeddu

المصدر: Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-16 (2023)

مصطلحات موضوعية: Bone marrow, Cardiac function, Dasatinib, db/db mouse model, Diabetic cardiomyopathy, Bone marrow-mesenchymal stem cells, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-2840

URL الوصول: https://doaj.org/article/182661119df04ef1b680839919bcac56

View record in DOAJ

Full Text Finder

2

Academic Journal

The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice

المؤلفون: Gu, Yue, Avolio, Elisa, Alvino, Valeria V, Thomas, Anita C, Herman, Andrew, Miller, Poppy J, Sullivan, Niall, Faulkner, Ashton R M, Madeddu, Paolo R

المصدر: Gu , Y , Avolio , E , Alvino , V V , Thomas , A C , Herman , A , Miller , P J , Sullivan , N , Faulkner , A R M & Madeddu , P R 2023 , ' The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice ' , Cardiovascular Diabetology , vol. 22 , no. 1 , 214 . https://doi.org/10.21203/rs.3.rs-3024470/v1 , https://doi.org/10.1186/s12933-023-01955-9

مصطلحات موضوعية: diabetes mellitus, Diabetic Cardiomyopathy, Dasatinib, cardiac steatosis, senolytic agent, db/db mouse model

Relation: https://research-information.bris.ac.uk/en/publications/42539718-4fd9-44af-83b0-4727effafed0

الاتاحة: https://hdl.handle.net/1983/42539718-4fd9-44af-83b0-4727effafed0
https://research-information.bris.ac.uk/en/publications/42539718-4fd9-44af-83b0-4727effafed0
https://doi.org/10.21203/rs.3.rs-3024470/v1

View record in BASE

3

Academic Journal

Influence of carnosine and carnosinase-1 on diabetes-induced afferent arteriole vasodilation:implications for glomerular hemodynamics

المؤلفون: Rodriguez-Nino, Angelica, Pastene, Diego O., Hettler, Steffen A., Qiu, Jiedong, Albrecht, Thomas, Vajpayee, Srishti, Perciaccante, Rossana, Gretz, Norbert, Bakker, Stephan J. L., Kraemer, Bernhard K., Yard, Benito A., van den Born, Jacob

المصدر: Rodriguez-Nino , A , Pastene , D O , Hettler , S A , Qiu , J , Albrecht , T , Vajpayee , S , Perciaccante , R , Gretz , N , Bakker , S J L , Kraemer , B K , Yard , B A & van den Born , J 2022 , ' Influence of carnosine and carnosinase-1 on diabetes-induced afferent arteriole vasodilation : implications for glomerular hemodynamics ' , American journal of physiology-Renal physiology , vol. 323 , no. 1 , pp. F69-F80 . https://doi.org/10.1152/ajprenal.00232.2021

مصطلحات موضوعية: carnosine, carnosinase-1, diabetic kidney disease, glomerular hemodynamics, glomerular hyper fi ltration, SINGLE-NEPHRON GFR, DB/DB MOUSE MODEL, RENAL-FUNCTION, CLINICAL-SIGNIFICANCE, GLUCOSE-INFUSION, LEUCINE REPEAT, KIDNEY-DISEASE, HYPERFILTRATION, CNDP1, MECHANISMS

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/2618c096-2d99-4f00-87ab-4140ad4c849a
https://research.rug.nl/en/publications/2618c096-2d99-4f00-87ab-4140ad4c849a
https://doi.org/10.1152/ajprenal.00232.2021
https://pure.rug.nl/ws/files/228552213/Influence_of_carnosine_and_carnosinase_1_on_diabetes_induced_afferent_arteriole_vasodilation_implications_for_glomerular_hemodynamics.pdf

View record in BASE

4

Academic Journal

Neuromodulation Induced by Sitagliptin : A New Strategy for Treating Diabetic Retinopathy

المؤلفون: Ramos, Hugo, Bogdanov, Patricia, Sabater, David, Huerta, Jordi, Valeri, Marta, HernÃ¡ndez, Cristina, SimÃ³ Canonge, Rafael, Universitat AutÃ²noma de Barcelona

مصطلحات موضوعية: Db/db mouse model, Diabetic retinopathy, Dipeptidyl peptidase 4 inhibitors, Presynaptic proteins, Retinal neurodegeneration, Sitagliptin

وصف الملف: application/pdf

Relation: Agencia Estatal de InvestigaciÃ³n PID2019-104225RB-I00; Instituto de Salud Carlos III PI19/01215; Instituto de Salud Carlos III ICI20/00129; Biomedicines; Vol. 9 (november 2021); https://ddd.uab.cat/record/292295; urn:10.3390/biomedicines9121772; urn:oai:ddd.uab.cat:292295; urn:pmcid:PMC8698405; urn:pmc-uid:8698405; urn:pmid:34944588; urn:oai:pubmedcentral.nih.gov:8698405; urn:oai:egreta.uab.cat:publications/7ce8ad5b-4b5e-454a-8544-64870b4d804b

الاتاحة: https://ddd.uab.cat/record/292295

View record in BASE

5

Academic Journal

Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy

المؤلفون: Hugo Ramos, Patricia Bogdanov, David Sabater, Jordi Huerta, Marta Valeri, Cristina Hernández, Rafael Simó

المصدر: Biomedicines; Volume 9; Issue 12; Pages: 1772

مصطلحات موضوعية: diabetic retinopathy, retinal neurodegeneration, dipeptidyl peptidase 4 inhibitors, sitagliptin, presynaptic proteins, db/db mouse model

وصف الملف: application/pdf

Relation: Neurobiology and Neurologic Disease; https://dx.doi.org/10.3390/biomedicines9121772

الاتاحة: https://doi.org/10.3390/biomedicines9121772

View record in BASE

6

Academic Journal

Gut Microbial Changes in Diabetic db/db Mice and Recovery of Microbial Diversity upon Pirfenidone Treatment

المؤلفون: Harinder Singh, Satoshi Miyamoto, Manjula Darshi, Manolito G. Torralba, Keehwan Kwon, Kumar Sharma, Rembert Pieper

المصدر: Microorganisms; Volume 8; Issue 9; Pages: 1347

مصطلحات موضوعية: gut microbiome, db/db mouse model, pirfenidone, cholecystokinin, type 2 diabetes, diabetic nephropathy, diabetic complications, kidney metabolism, metagenomics

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Gut Microbiota; https://dx.doi.org/10.3390/microorganisms8091347

الاتاحة: https://doi.org/10.3390/microorganisms8091347

View record in BASE

7

Academic Journal

Ultrastructural Remodeling of the Neurovascular Unit in the Female Diabetic db/db Model—Part III: Oligodendrocyte and Myelin

المؤلفون: Melvin Hayden, Deana Grant, Aranyra Aroor, Vincent DeMarco

المصدر: Neuroglia; Volume 1; Issue 2; Pages: 351-364

مصطلحات موضوعية: db/db mouse model, myelin, neurovascular unit, oligodendrocyte, subcortical white matter, type 2 diabetes

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/neuroglia1020024

الاتاحة: https://doi.org/10.3390/neuroglia1020024

View record in BASE

8

Academic Journal

Ultrastructural Remodeling of the Neurovascular Unit in the Female Diabetic db/db Model–Part II: Microglia and Mitochondria

المؤلفون: Melvin Hayden, DeAna Grant, Annayya Aroor, Vincent DeMarco

المصدر: Neuroglia; Volume 1; Issue 2; Pages: 311-326

مصطلحات موضوعية: astrocyte, db/db mouse model, microglia, mitochondria, neuroglia, neurovascular unit, type 2 diabetes

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/neuroglia1020021

الاتاحة: https://doi.org/10.3390/neuroglia1020021

View record in BASE

9

Academic Journal

Ultrastructural Remodeling of the Neurovascular Unit in the Female Diabetic db/db Model—Part I: Astrocyte

المؤلفون: Melvin Hayden, DeAna Grant, Annayya Aroor, Vincent DeMarco

المصدر: Neuroglia; Volume 1; Issue 1; Pages: 220-244

مصطلحات موضوعية: astrocyte, db/db mouse model, microglia, neuroglia, neurovascular unit, type 2 diabetes

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/neuroglia1010015

الاتاحة: https://doi.org/10.3390/neuroglia1010015

View record in BASE

10

Influence of carnosine and carnosinase-1 on diabetes-induced afferent arteriole vasodilation: implications for glomerular hemodynamics

المؤلفون: Angelica Rodriguez-Niño, Diego O. Pastene, Steffen A. Hettler, Jiedong Qiu, Thomas Albrecht, Srishti Vajpayee, Rossana Perciaccante, Norbert Gretz, Stephan J. L. Bakker, Bernhard K. Krämer, Benito A. Yard, Jacob van den Born

المساهمون: Groningen Institute for Organ Transplantation (GIOT), Groningen Kidney Center (GKC)

المصدر: American journal of physiology-Renal physiology, 323(1), F69-F80. AMER PHYSIOLOGICAL SOC

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b43ca785eec50d33a57e96878f342d4
https://pubmed.ncbi.nlm.nih.gov/35635322

View record in OpenAIRE

11

Academic Journal

HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice

المؤلفون: Jingya Li, Tao Wang, Luyong Zhang, Chao Guo, Bo Jiang, Shuju Guo, Dayong Shi

المصدر: Marine Drugs, Vol 11, Iss 2, Pp 350-362 (2013)

مصطلحات موضوعية: bromophenol, protein tyrosine phosphatase 1B inhibitor, db/db mouse model, anti-diabetes properties, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1660-3397/11/2/350; https://doaj.org/toc/1660-3397

URL الوصول: https://doaj.org/article/dca79c8e146c441abbdb8118ef055082

View record in DOAJ

Full Text Finder

12

Neuromodulation Induced by Sitagliptin: A New Strategy for Treating Diabetic Retinopathy

المؤلفون: Cristina Hernández, David Sabater, Jordi Huerta, Patricia Bogdanov, Hugo Ramos, Marta Valeri, Rafael Simó

المساهمون: Institut Català de la Salut, [Ramos H, Bogdanov P, Hernández C, Simó R] Unitat de Recerca en Diabetis i Metabolisme, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ICSIII), Madrid, Spain. [Sabater D, Huerta J] Unitat de Recerca en Diabetis i Metabolisme, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Valeri M] Unitat d'Alta Tecnologia, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Biomedicines
Biomedicines; Volume 9; Issue 12; Pages: 1772
Scientia
Biomedicines, Vol 9, Iss 1772, p 1772 (2021)

مصطلحات موضوعية: enfermedades del sistema endocrino::diabetes mellitus::complicaciones de la diabetes::angiopatías diabéticas::retinopatía diabética [ENFERMEDADES], Synapsin I, Endocrine System Diseases::Diabetes Mellitus::Diabetes Complications::Diabetic Angiopathies::Diabetic Retinopathy [DISEASES], QH301-705.5, Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Protease Inhibitors::Dipeptidyl-Peptidase IV Inhibitors [CHEMICALS AND DRUGS], diabetic retinopathy, retinal neurodegeneration, dipeptidyl peptidase 4 inhibitors, sitagliptin, presynaptic proteins, db/db mouse model, Otros calificadores::Otros calificadores::/farmacoterapia [Otros calificadores], Medicine (miscellaneous), Pharmacology, Other subheadings::Other subheadings::/drug therapy [Other subheadings], Peptidases - Inhibidors, General Biochemistry, Genetics and Molecular Biology, Article, Downregulation and upregulation, acciones y usos químicos::acciones farmacológicas::mecanismos moleculares de acción farmacológica::inhibidores enzimáticos::inhibidores de proteasas::inhibidores de la dipeptidil-peptidasa IV [COMPUESTOS QUÍMICOS Y DROGAS], Medicine, Other subheadings::/therapeutic use [Other subheadings], Biology (General), biology, VAMP2, Otros calificadores::/uso terapéutico [Otros calificadores], STX1A, business.industry, SNAP25, Retinopatia diabètica - Tractament, Membrane protein, Sitagliptin, Synaptophysin, biology.protein, business, medicine.drug