المؤلفون: Dimitri Krainc, Aaron M. Earley, Rajeshwar Awatramani, Lena F. Burbulla

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific reports 11(1), 22257 (2021). doi:10.1038/s41598-021-01366-4

مصطلحات موضوعية: Neurogenesis, Cellular differentiation, Science, Induced Pluripotent Stem Cells, Stem-cell differentiation, genetics [Basic Helix-Loop-Helix Transcription Factors], Developmental neurogenesis, Biology, Article, ASCL1 protein, human, Basic Helix-Loop-Helix Transcription Factors, Humans, Gene Regulatory Networks, Induced pluripotent stem cell, Transcription factor, methods [Computational Biology], cytology [Dopaminergic Neurons], Regulation of gene expression, Multidisciplinary, genetics [Cell Differentiation], Dopaminergic Neurons, Gene Expression Profiling, metabolism [Dopaminergic Neurons], Computational Biology, Gene Expression Regulation, Developmental, High-Throughput Nucleotide Sequencing, Cell Differentiation, cytology [Induced Pluripotent Stem Cells], Cell biology, metabolism [Induced Pluripotent Stem Cells], ASCL1, NEUROD1, Neuronal development, Medicine, Stem cell, ddc:600, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8456125706a31a7ab6245db54f126b4
https://doaj.org/article/c21875a492da40c9b0c929e0d4c3f82a

المؤلفون: Eldem Sadikoglou, Joachim Täger, Manmeet-Sakshi Bedi, Noemia Fernandes, Stefanie Bröer, Peter Heutink, Salvador Rodriguez-Nieto, Ashutosh Dhingra, Patrizia Rizzu, Elisangela Bressan, Melissa Castillo-Lizardo

المصدر: JoVE journal Biology(162), 61525 (2020). doi:10.3791/61525

مصطلحات موضوعية: Cell type, Neurite, Cell Survival, General Chemical Engineering, Induced Pluripotent Stem Cells, Neuronal Outgrowth, Cell, Cell Culture Techniques, Cell Count, Biology, General Biochemistry, Genetics and Molecular Biology, cytology [Cerebral Cortex], Automation, User-Computer Interface, Neural Stem Cells, Mesencephalon, ddc:570, Precursor cell, methods [Cell Culture Techniques], Image Processing, Computer-Assisted, medicine, Humans, CRISPR, cytology [Neural Stem Cells], Induced pluripotent stem cell, Cells, Cultured, cytology [Dopaminergic Neurons], cytology [Mesencephalon], Cerebral Cortex, General Immunology and Microbiology, Dopaminergic Neurons, General Neuroscience, Dopaminergic, Cell Differentiation, cytology [Induced Pluripotent Stem Cells], Carbon Dioxide, medicine.anatomical_structure, Cell culture, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522281cdee11ab0c7713c21844c76581
https://doi.org/10.3791/61525

المؤلفون: Cathleen Hagemann, Ankita Ravi Vaswani, Hans-Ulrich Fried, Beatrice Weykopf, Oliver Brüstle, Sandra Blaess

المصدر: eLife 8, e41623 (2019). doi:10.7554/eLife.41623
eLife, Vol 8 (2019)
eLife

مصطلحات موضوعية: Mouse, cytology [Ventral Tegmental Area], time-lapse imaging, Cell morphology, Mice, 0302 clinical medicine, Mesencephalon, Cell Movement, Reelin, Biology (General), Phosphorylation, skin and connective tissue diseases, cell morphology, 0303 health sciences, Extracellular Matrix Proteins, biology, Chemistry, General Neuroscience, Dopaminergic, Serine Endopeptidases, metabolism [Dopaminergic Neurons], metabolism [Extracellular Matrix Proteins], General Medicine, DAB1, Ventral tegmental area, Substantia Nigra, medicine.anatomical_structure, cell tracking, Medicine, Research Article, Signal Transduction, QH301-705.5, Cell Adhesion Molecules, Neuronal, Science, Dab1, Substantia nigra, Nerve Tissue Proteins, cytology [Substantia Nigra], General Biochemistry, Genetics and Molecular Biology, Midbrain, 03 medical and health sciences, metabolism [Cell Adhesion Molecules, Neuronal], metabolism [Serine Endopeptidases], medicine, Animals, Cell Shape, 030304 developmental biology, cytology [Dopaminergic Neurons], cytology [Mesencephalon], organotypic slice cultures, metabolism [Nerve Tissue Proteins], General Immunology and Microbiology, Pars compacta, Dopaminergic Neurons, Ventral Tegmental Area, Reelin Protein, dopaminergic system, nervous system, biology.protein, Neuroscience, ddc:600, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16e9515bb9ac1da90dcaee268fb3cd2
https://pub.dzne.de/record/140450

المؤلفون: Benedict Rauser, Jingzhong Zhang, Nilima Prakash, Marina Theodorou, Wolfgang Wurst, Joel A. Schick

المصدر: Human gene therapy / Methods 26(4), 107-122 (2015). doi:10.1089/hgtb.2014.152

مصطلحات موضوعية: Ascl1 protein, mouse, Male, Somatic cell, Gene Expression, Applied Microbiology and Biotechnology, Lmx1a protein, mouse, Mice, Transduction, Genetic, Gene Order, Nuclear Receptor Subfamily 4, Group A, Member 2, Basic Helix-Loop-Helix Transcription Factors, Transgenes, Homologous Recombination, Genetics (clinical), Genetics, metabolism [Astrocytes], Cell Death, metabolism [Dopaminergic Neurons], Dopaminergic, genetics [Transcription Factors], Cellular Reprogramming, Cell biology, genetics [Cellular Reprogramming], genetics [Cell Death], Molecular Medicine, Female, Nr4a2 protein, mouse, Reprogramming, Programmed cell death, genetics [LIM-Homeodomain Proteins], Genetic Vectors, LIM-Homeodomain Proteins, genetics [Basic Helix-Loop-Helix Transcription Factors], Mice, Transgenic, Substantia nigra, Biology, genetics [Unfolded Protein Response], Cell Line, In vivo, Animals, ddc:610, Transcription factor, Embryonic Stem Cells, genetics [Lentivirus], cytology [Dopaminergic Neurons], Pharmacology, genetics [Nuclear Receptor Subfamily 4, Group A, Member 2], genetics [Genetic Vectors], Dopaminergic Neurons, Lentivirus, Fibroblasts, Embryonic stem cell, nervous system, Astrocytes, Unfolded Protein Response, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710c6b6b8dc78d56ee894acb76f9a916
https://doi.org/10.1089/hgtb.2014.152

المؤلفون: Marius Ader, M Ehrhart-Bornstein, Graeme Eisenhofer, Sven Lange, Kuei-Fang Chung, Vladimir Vukicevic, Linda Gebauer, Stefan R. Bornstein, Ursula Ravens, Nan Qin, Janine Schmid, Andreas Hermann, Alexander Storch

المصدر: Cell transplantation 21(11), 2471-2486 (2012). doi:10.3727/096368912X638874
Cell Transplantation, Vol 21 (2012)

مصطلحات موضوعية: endocrine system, Parkinson's disease, Chromaffin Cells, metabolism [Stem Cells], Biomedical Engineering, Retinoic acid, lcsh:Medicine, Tretinoin, metabolism [Tretinoin], Biology, cytology [Stem Cells], chemistry.chemical_compound, medicine, Animals, ddc:610, Progenitor cell, Cells, Cultured, Cell Proliferation, cytology [Dopaminergic Neurons], Transplantation, Dopaminergic Neurons, Stem Cells, lcsh:R, metabolism [Dopaminergic Neurons], Dopaminergic, Cell Differentiation, metabolism [Chromaffin Cells], Cell Biology, medicine.disease, Ascorbic acid, physiology [Cell Differentiation], chemistry, cytology [Chromaffin Cells], Cattle, Neural differentiation, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111ebbf0abb0920530ed6d11ea0b3634
https://doi.org/10.3727/096368912x638874

المؤلفون: Andreas Hermann, Katja Schurig, Alexander Storch, Carsten Werner, Milauscha Grimmer, Uwe Freudenberg, Sabine Heidel, Andrea Zieris

المصدر: Biomaterials 67, 205-213 (2015). doi:10.1016/j.biomaterials.2015.07.029

مصطلحات موضوعية: pharmacology [Glial Cell Line-Derived Neurotrophic Factor], drug effects [Neural Stem Cells], pharmacology [Fibroblast Growth Factor 2], drug effects [Dopaminergic Neurons], Fibroblast growth factor, Polyethylene Glycols, Neural Stem Cells, Mesencephalon, Neurotrophic factors, Glial cell line-derived neurotrophic factor, chemistry [Heparin], cytology [Neural Stem Cells], Cells, Cultured, Glycosaminoglycans, biology, cytology [Neuroglia], drug effects [Cell Differentiation], Dopaminergic, Cell Differentiation, metabolism [Neurites], Hydrogels, cytology [Fetus], Neural stem cell, Cell biology, methods [Tissue Engineering], Biochemistry, Mechanics of Materials, Female, Fibroblast Growth Factor 2, Neuroglia, pharmacology [Nerve Growth Factors], Materials science, Neurite, Cell Survival, drug effects [Cell Survival], Biophysics, drug effects [Neurites], Bioengineering, chemical synthesis [Hydrogels], chemical synthesis [Polyethylene Glycols], Biomaterials, drug effects [Neuroglia], Fetus, ddc:570, Neurites, Animals, Glial Cell Line-Derived Neurotrophic Factor, Nerve Growth Factors, cytology [Dopaminergic Neurons], cytology [Mesencephalon], Tissue Engineering, Heparin, Dopaminergic Neurons, Regeneration (biology), Mice, Inbred C57BL, Drug Liberation, Ceramics and Composites, biology.protein, pharmacology [Glycosaminoglycans], GDNF family of ligands

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca4ab595d68dffc47a9d4d8da320f8e
https://pub.dzne.de/record/138111

المؤلفون: Nilima Prakash, Ralf Kuehn, Martin Irmler, Wolfgang Wurst, Anna Pertek, Max Endele, Johannes Beckers, Stavroula Skylaki, Florian Meier

المصدر: Molecular biotechnology 56(8), 697-713 (2014). doi:10.1007/s12033-014-9748-y

مصطلحات موضوعية: Male, Transgene, Genetic Vectors, Green Fluorescent Proteins, Induced Pluripotent Stem Cells, Cre recombinase, Bioengineering, Mice, Transgenic, Biology, genetics [Integrases], Applied Microbiology and Biotechnology, Biochemistry, Regenerative medicine, Mice, Genes, Reporter, ddc:570, Recombinase, genetics [Green Fluorescent Proteins], Animals, Induced pluripotent stem cell, Molecular Biology, Cells, Cultured, Genetics, cytology [Dopaminergic Neurons], Mice, Inbred BALB C, transplantation [Induced Pluripotent Stem Cells], Integrases, Dopaminergic Neurons, metabolism [Dopaminergic Neurons], Cell Differentiation, cytology [Induced Pluripotent Stem Cells], Cellular Reprogramming, Embryonic stem cell, Integrase, Cell biology, metabolism [Induced Pluripotent Stem Cells], genetics [Cellular Reprogramming], biology.protein, Female, Transcriptome, Reprogramming, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344d85738787445353001d037b6b7d88
https://pubmed.ncbi.nlm.nih.gov/24677035

المؤلفون: Carsten Culmsee, Bastian Hengerer, Anderson de Andrade, Matthias Höllerhage, Tobias Hildebrandt, Günter U. Höglinger, Wolfgang H. Oertel, Joachim N. Goebel, Amalia M. Dolga

المصدر: Neurobiology of aging 35(7), 1700-1711 (2014). doi:10.1016/j.neurobiolaging.2014.01.027

مصطلحات موضوعية: Aging, Programmed cell death, pathology [Dopaminergic Neurons], drug effects [Autophagy], pharmacology [Trifluoperazine], pharmacology [Antipsychotic Agents], drug effects [Dopaminergic Neurons], Trifluoperazine, Pharmacology, Biology, toxicity [alpha-Synuclein], Neuroprotection, chemistry.chemical_compound, genetics [Parkinson Disease], Dopaminergic Cell, medicine, Autophagy, Humans, ddc:610, Molecular Targeted Therapy, metabolism [alpha-Synuclein], Cells, Cultured, Alpha-synuclein, cytology [Dopaminergic Neurons], General Neuroscience, Dopaminergic Neurons, Neurodegeneration, Neurotoxicity, Parkinson Disease, medicine.disease, metabolism [Lewy Bodies], drug therapy [Parkinson Disease], Cell biology, pathology [Parkinson Disease], nervous system, chemistry, therapeutic use [Antipsychotic Agents], alpha-Synuclein, Lewy Bodies, Neurology (clinical), Geriatrics and Gerontology, therapeutic use [Trifluoperazine], Developmental Biology, medicine.drug, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccc30d9961bcc0365778dcb18dba8c5

المؤلفون: Nilima Prakash, Wolfgang Wurst

المصدر: Journal of Molecular Cell Biology; Vol 6
Journal of molecular cell biology 6(1), 34-41 (2013). doi:10.1093/jmcb/mjt046
J. Mol. Cell Biol. 6, 34-41 (2014)

مصطلحات موضوعية: medicine.medical_specialty, Population, physiology [Wnt Signaling Pathway], Wnt1 Protein, Biology, Models, Biological, Midbrain, chemistry.chemical_compound, Mice, Dopamine, Mesencephalon, ddc:570, Dopaminergic Cell, Internal medicine, metabolism [Wnt1 Protein], Genetics, medicine, Animals, Gene Regulatory Networks, WNT1, physiology [Dopaminergic Neurons], education, Neurotransmitter, Molecular Biology, Wnt Signaling Pathway, Wnt1, Neuron, Ventral Midbrain, Mouse, cytology [Dopaminergic Neurons], cytology [Mesencephalon], education.field_of_study, Dopaminergic Neurons, metabolism [Dopaminergic Neurons], genetics [Wnt1 Protein], physiology [Wnt1 Protein], Cell Biology, General Medicine, Embryonic stem cell, ddc, medicine.anatomical_structure, Endocrinology, nervous system, chemistry, Neuroscience, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87beca8014d0d9f0948b4ec1894eab8e
https://pubmed.ncbi.nlm.nih.gov/24326514

المؤلفون: Höglinger, Günter U, Arias-Carrión, Oscar, Ipach, Bastian, Oertel, Wolfgang H

المصدر: The journal of comparative neurology 522(10), 2336-2348 (2014). doi:10.1002/cne.23537

مصطلحات موضوعية: cytology [Dopaminergic Neurons], Male, anatomy & histology [Lateral Ventricles], anatomy & histology [Ventral Tegmental Area], anatomy & histology [Hippocampus], Dopaminergic Neurons, Neurogenesis, Green Fluorescent Proteins, Ventral Tegmental Area, Fluorescent Antibody Technique, Mice, Transgenic, Hippocampus, anatomy & histology [Pars Compacta], Neuroanatomical Tract-Tracing Techniques, Bromodeoxyuridine, Neural Stem Cells, Lateral Ventricles, Neural Pathways, genetics [Green Fluorescent Proteins], Animals, ddc:610, cytology [Neural Stem Cells], Rats, Wistar, Pars Compacta, anatomy & histology [Neural Pathways]

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fb8bb5fa38d118ed3ded73f70a6e8161
https://pubmed.ncbi.nlm.nih.gov/24424877

المؤلفون: H-G. Knaus, Hans Zischka, Nikolaus Plesnila, Matthias Höllerhage, Carsten Culmsee, Günter U. Höglinger, A de Andrade, Lilja Meissner, Amalia M. Dolga, P Christophersen

المصدر: Cell Death & Disease
Cell death & disease 5(1), e999-e999 (2014). doi:10.1038/cddis.2013.530

مصطلحات موضوعية: Cancer Research, Small-Conductance Calcium-Activated Potassium Channels, KCNN3 protein, human, Parkinson's disease, Immunology, Excitotoxicity, metabolism [Parkinson Disease], KCNN2 protein, human, Pharmacology, Biology, medicine.disease_cause, Neuroprotection, SK channel, Cellular and Molecular Neuroscience, SK3, genetics [Parkinson Disease], Dopaminergic Cell, ddc:570, metabolism [Mitochondrial Membranes], medicine, Humans, metabolism [Calcium], metabolism [Small-Conductance Calcium-Activated Potassium Channels], KCNN1 protein, human, Membrane potential, cytology [Dopaminergic Neurons], Membrane Potential, Mitochondrial, Dopaminergic Neurons, Dopaminergic, metabolism [Dopaminergic Neurons], Cell Differentiation, Parkinson Disease, Cell Biology, pre-conditioning, Potassium channel, mitochondria, Protein Transport, NS309, Neuroprotective Agents, genetics [Small-Conductance Calcium-Activated Potassium Channels], Mitochondrial Membranes, Calcium, Original Article, physiopathology [Parkinson Disease], SK channels, metabolism [Neuroprotective Agents]

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf9e3f82cac3b3215981b433de92087
https://pubmed.ncbi.nlm.nih.gov/24434522

المؤلفون: Jan C. Koch, Elisabeth Barski, Mathias Bähr, Murielle Salomé, Paul Lingor, Tanja Dučić

المصدر: Journal of neurochemistry 124, 250 (2013). doi:10.1111/jnc.12073
Journal of Neurochemistry

مصطلحات موضوعية: Parkinson's disease, Manganese, medicine.disease_cause, Biochemistry, X-ray fluorescence microscopy, Mice, 0302 clinical medicine, metabolism [Iron], 0303 health sciences, education.field_of_study, Dopaminergic, Parkinson Disease, 3. Good health, iron, manganese, oxidative state, Parkinson’s disease, primary dopaminergic neurons, medicine.drug, endocrine system, Iron, Population, Primary Cell Culture, Green Fluorescent Proteins, metabolism [Parkinson Disease], chemistry.chemical_element, Substantia nigra, Mice, Transgenic, Ferrous, 03 medical and health sciences, Cellular and Molecular Neuroscience, Dopamine, methods [Spectrometry, X-Ray Emission], medicine, Animals, genetics [Green Fluorescent Proteins], ddc:610, education, physiology [Dopaminergic Neurons], 030304 developmental biology, cytology [Dopaminergic Neurons], Pars compacta, Dopaminergic Neurons, Spectrometry, X-Ray Emission, Original Articles, metabolism [Manganese], pathology [Parkinson Disease], chemistry, Biophysics, 030217 neurology & neurosurgery, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6660abeda4930231c1d569c4bb5f24b
https://bib-pubdb1.desy.de/record/139494

المؤلفون: Kai F. Loewenbrück, Änne Boldt, Georg Breier, Joanna Kalucka, Johannes Schwarz, Martina Maisel, Christiane Fiedler, Alexander Storch, Andreas Hermann

المصدر: Neuroscience letters 553, 142-147 (2013). doi:10.1016/j.neulet.2013.08.031
Hermann, A, Loewenbrück, K F, Boldt, Ä, Fiedler, C, Maisel, M, Kalucka, J, Schwarz, J, Breier, G & Storch, A 2013, ' Lack of vascular endothelial growth factor receptor-2/Flk1 signaling does not affect substantia nigra development ', Neuroscience Letters, vol. 553, pp. 142-7 . https://doi.org/10.1016/j.neulet.2013.08.031

مصطلحات موضوعية: medicine.medical_specialty, Cell Survival, Neurogenesis, Cre recombinase, Substantia nigra, Mice, Transgenic, Biology, chemistry.chemical_compound, Mice, Internal medicine, embryology [Substantia Nigra], medicine, metabolism [Substantia Nigra], Animals, ddc:610, Dopaminergic Neurons/cytology, Vascular Endothelial Growth Factor Receptor-2/genetics, cytology [Dopaminergic Neurons], Dopaminergic Neurons, General Neuroscience, Substantia Nigra/embryology, Dopaminergic, Kinase insert domain receptor, Vascular Endothelial Growth Factor Receptor-2, Oxygen tension, Cell biology, Substantia Nigra, Vascular endothelial growth factor, metabolism [Vascular Endothelial Growth Factor Receptor-2], Endocrinology, growth & development [Substantia Nigra], nervous system, chemistry, genetics [Vascular Endothelial Growth Factor Receptor-2], Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40991bd0195e38affd48a6ddbcecfaea
https://pub.dzne.de/record/137087

المؤلفون: Ina Nuesslein, Stefan Kißenkötter, Alexander Jarosch, Alexander Storch, Anne K. Meyer, Katja Schurig

المصدر: Brain research 1474, 8-18 (2012). doi:10.1016/j.brainres.2012.07.034

مصطلحات موضوعية: Cell Culture Techniques, Biology, Mice, Fetus, Neuroblast, Neural Stem Cells, Dopamine, Mesencephalon, Neurosphere, otorhinolaryngologic diseases, medicine, methods [Cell Culture Techniques], Animals, ddc:610, cytology [Neural Stem Cells], Molecular Biology, Cells, Cultured, cytology [Dopaminergic Neurons], cytology [Mesencephalon], General Neuroscience, Dopaminergic Neurons, Dopaminergic, Cell Differentiation, Embryonic stem cell, Neural stem cell, Transplantation, stomatognathic diseases, physiology [Cell Differentiation], Neurology (clinical), Stem cell, Neuroscience, Developmental Biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15a612660b3bf4dc60f4037d70f8ea5
https://pubmed.ncbi.nlm.nih.gov/22842082

المؤلفون: Ruth Klafke, A. Alwin Prem Anand, Andrea Wizenmann, Wolfgang Wurst, Nilima Prakash

المصدر: Europe PubMed Central
Development 143, 691-702 (2016)
Development 143(4), 691-702 (2016). doi:10.1242/dev.126748

مصطلحات موضوعية: 0301 basic medicine, metabolism [Neural Stem Cells], Chick Embryo, Mice, Diencephalon, Neural Stem Cells, Mesencephalon, metabolism [Homeodomain Proteins], metabolism [Transcription Factors], cytology [Neural Stem Cells], Zebrafish, Genetics, metabolism [Mesencephalon], Dopamine Precursors, Chicken, Mouse, Pitx3, Wnt9a, Shh, genetics [Wnt Proteins], metabolism [Dopaminergic Neurons], Dopaminergic, Gene Expression Regulation, Developmental, genetics [Transcription Factors], Neural stem cell, metabolism [Diencephalon], Cell biology, cytology [Diencephalon], medicine.anatomical_structure, embryonic structures, metabolism [Hedgehog Proteins], Signal transduction, homeobox protein PITX3, metabolism [Biomarkers], Signal Transduction, animal structures, genetics [Homeodomain Proteins], Mitosis, genetics [Chickens], Biology, genetics [Signal Transduction], Models, Biological, Midbrain, 03 medical and health sciences, metabolism [Wnt Proteins], Spatio-Temporal Analysis, ddc:570, medicine, Animals, Humans, Hedgehog Proteins, Molecular Biology, Transcription factor, Cell Proliferation, cytology [Dopaminergic Neurons], cytology [Mesencephalon], Homeodomain Proteins, Dopaminergic Neurons, Epistasis, Genetic, biology.organism_classification, Wnt Proteins, 030104 developmental biology, nervous system, Neuron, Chickens, Biomarkers, Transcription Factors, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583e3ddbc34d25dcc518b748ee6ec0a1
http://europepmc.org/abstract/med/26755703