المؤلفون: He, AWJ, Ngai, SPC, Cheung, KK, Lau, BWM, Sánchez-Vidaña, DI, Pang, MYC

المساهمون: Department of Rehabilitation Sciences

مصطلحات موضوعية: Chronic obstructive pulmonary disease (COPD), Cigarette smoke (CS), Cross-sectional area, Fiber type composition, Muscle derangement, Rodents

Relation: http://hdl.handle.net/10397/99973; 10; 2-s2.0-85130873858; 262; OA_Scopus/WOS

الاتاحة: http://hdl.handle.net/10397/99973
https://doi.org/10.3390/toxics10050262

المؤلفون: Marko Manevski, Dinesh Devadoss, Christopher Long, Shashi P. Singh, Mohd Wasim Nasser, Glen M. Borchert, Madhavan N. Nair, Irfan Rahman, Mohan Sopori, Hitendra S. Chand

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: bronchial epithelial cells, cigarette smoke (CS), chronic obstructive pulmonary disease (COPD), long noncoding RNA (lncRNA), mucus hyperexpression, lncRNA antisense to ICAM-1 (LASI), Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.988069/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/dcd36f61998d47209fdff4db8935eb12

المؤلفون: Marko Manevski, Dinesh Devadoss, Christopher Long, Shashi P. Singh, Mohd Wasim Nasser, Glen M. Borchert, Madhavan N. Nair, Irfan Rahman, Mohan Sopori, Hitendra S. Chand

المصدر: Frontiers in Immunology, Vol 13 (2022)

مصطلحات موضوعية: bronchial epithelial cells, cigarette smoke (CS), chronic obstructive pulmonary disease (COPD), long noncoding RNA (lncRNA), mucus hyperexpression, lncRNA antisense to ICAM-1 (LASI), Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.803362/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/db0d9c3561534968a4300602e1f7a12b

المؤلفون: Steven P. Cass, Olivia Mekhael, Danya Thayaparan, Joshua J. C. McGrath, Spencer D. Revill, Matthew F. Fantauzzi, Peiyao Wang, Amir Reihani, Aaron I. Hayat, Christopher S. Stevenson, Anna Dvorkin-Gheva, Fernando M. Botelho, Martin R. Stämpfli, Kjetil Ask

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: macrophage, cigarette smoke (CS), immunopathology, tissue remodelling, fibrogenesis, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.740330/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/42863354dc984044af4890b5d31645bc

المؤلفون: Francesca Polverino, Farrah Kheradmand

المصدر: Frontiers in Medicine, Vol 7 (2021)

مصطلحات موضوعية: COPD, COVID-19, SARS-CoV-2, cigarette smoke (CS), therapy, endothelium, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2020.627278/full; https://doaj.org/toc/2296-858X

URL الوصول: https://doaj.org/article/52724827b3054e4fa0878e38ef50b712

المؤلفون: Shahdat Hossain, Marzan Sarkar, Sujan Bhowmick, Jakir Hussain, Mahmudul Hasan, Borhan Uddin, Md. Asaduzzaman Khan, Taslima Nahar

المصدر: African Journal of Biological Sciences, Vol 3, Iss 1, Pp 120-128 (2021)

مصطلحات موضوعية: cigarette smoke (cs), lung, erythrocyte, lipid peroxidation (lpo), tumor necrosis factor-α (tnf-α), Microbiology, QR1-502, Aquaculture. Fisheries. Angling, SH1-691

Relation: https://www.afjbs.com/files/1609745375_(11)_AFJBS20210109_(p_120-128).pdf; https://doaj.org/toc/2663-2187; https://doaj.org/article/6373986e32f245309066f137f346f62e

الاتاحة: https://doi.org/10.33472/AFJBS.3.1.2021.120-128
https://doaj.org/article/6373986e32f245309066f137f346f62e

المؤلفون: Santanu Banerjee

مصطلحات موضوعية: Chronic Obstructive Pulmonary Diseases (Copd) Cigarette Smoke (Cs) Lung Oxidative Stress Inflammation Airway-Remodeling

Relation: https://doi.org/10.5281/zenodo.3663534; https://doi.org/10.5281/zenodo.3663535; oai:zenodo.org:3663535

الاتاحة: https://doi.org/10.5281/zenodo.3663535

المؤلفون: Bartosz Pilecki, Helle Wulf-Johansson, Christian Støttrup, Patricia Troest Jørgensen, Pascal Djiadeu, Anders Bathum Nexøe, Anders Schlosser, Søren Werner Karlskov Hansen, Jens Madsen, Howard William Clark, Claus Henrik Nielsen, Jørgen Vestbo, Nades Palaniyar, Uffe Holmskov, Grith Lykke Sorensen

المصدر: Frontiers in Immunology, Vol 9 (2018)

مصطلحات موضوعية: surfactant protein D (SP-D), cigarette smoke (CS), mouse models, ceramide, ceramide synthase, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.03013/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/8c41a14a56ed416b9f9e365b528dec9c

المؤلفون: Liu, Gang, Haw, Tatt Jhong, Starkey, Malcolm R, Philp, Ashleigh M, Pavlidis, Stelios, Nalkurthi, Christina, Nair, Prema M, Gomez, Henry M, Hanish, Irwan, Hsu, Alan Cy, Hortle, Elinor, Pickles, Sophie, Rojas-Quintero, Joselyn, Estepar, Raul San Jose, Marshall, Jacqueline E, Kim, Richard Y, Collison, Adam M, Mattes, Joerg, Idrees, Sobia, Faiz, Alen, Hansbro, Nicole G, Fukui, Ryutaro, Murakami, Yusuke, Cheng, Hong Sheng, Tan, Nguan Soon, Chotirmall, Sanjay H, Horvat, Jay C, Foster, Paul S, Oliver, Brian Gg, Polverino, Francesca, Ieni, Antonio, Monaco, Francesco, Caramori, Gaetano, Sohal, Sukhwinder S, Bracke, Ken R, Wark, Peter A, Adcock, Ian M, Miyake, Kensuke, Sin, Don D, Hansbro, Philip M

المساهمون: Liu, Gang, Haw, Tatt Jhong, Starkey, Malcolm R, Philp, Ashleigh M, Pavlidis, Stelio, Nalkurthi, Christina, Nair, Prema M, Gomez, Henry M, Hanish, Irwan, Hsu, Alan Cy, Hortle, Elinor, Pickles, Sophie, Rojas-Quintero, Joselyn, Estepar, Raul San Jose, Marshall, Jacqueline E, Kim, Richard Y, Collison, Adam M, Mattes, Joerg, Idrees, Sobia, Faiz, Alen, Hansbro, Nicole G, Fukui, Ryutaro, Murakami, Yusuke, Cheng, Hong Sheng, Tan, Nguan Soon, Chotirmall, Sanjay H, Horvat, Jay C, Foster, Paul S, Oliver, Brian Gg, Polverino, Francesca, Ieni, Antonio, Monaco, Francesco, Caramori, Gaetano, Sohal, Sukhwinder S, Bracke, Ken R, Wark, Peter A, Adcock, Ian M, Miyake, Kensuke, Sin, Don D, Hansbro, Philip M

مصطلحات موضوعية: Toll-like receptor 7 (TLR7) is known for eliciting immunity against single-stranded RNA viruses, and is increased in both human and cigarette smoke (CS)-induced, experimental chronic obstructive pulmonary disease (COPD). Here we show that the severity of CS-induced emphysema and COPD is reduced in TLR7-deficient mice, while inhalation of imiquimod, a TLR7-agonist, induces emphysema without CS exposure. This imiquimod-induced emphysema is reduced in mice deficient in mast cell protease-6, or when wild-type mice are treated with the mast cell stabilizer, cromolyn. Furthermore, therapeutic treatment with anti-TLR7 monoclonal antibody suppresses CS-induced emphysema, experimental COPD and accumulation of pulmonary mast cells in mice. Lastly, TLR7 mRNA is increased in pre-existing datasets from patients with COPD, while TLR7+ mast cells are increased in COPD lungs and associated with severity of COPD. Our results thus support roles for TLR7 in mediating emphysema and COPD through mast cell activity, and may implicate TLR7 as a potential therapeutic target

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001104729800026; volume:14; issue:1; firstpage:7349; journal:NATURE COMMUNICATIONS; https://hdl.handle.net/11381/2964952; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85176384352

الاتاحة: https://hdl.handle.net/11381/2964952
https://doi.org/10.1038/s41467-023-42913-z

المؤلفون: Rui Xiong, Levan Muskhelishvili, Tao Chen, Yue Wu, Qiangen Wu, Xuefei Cao, Priya Tripathi, Hans Rosenfeldt, Kelly Davis, Matthew Bryant, Sheila M Healy, Ying Chen

المصدر: Archives of Toxicology

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Health, Toxicology and Mutagenesis, Chronic obstructive pulmonary disease (COPD), Bronchi, Toxicology, medicine.disease_cause, Organ Toxicity and Mechanisms, Pathogenesis, Transcriptome, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, 0302 clinical medicine, Smoke, Tobacco, Toxicity Tests, Animals, Humans, Medicine, Respiratory system, Lung cancer, Lung, Cells, Cultured, Transcriptomic profiling, COPD, business.industry, Gene Expression Profiling, Smoking, Mucin, Air–liquid-interface (ALI) airway tissue model, Epithelial Cells, Pathophysiologically relevant endpoints, General Medicine, medicine.disease, Oxidative Stress, 030104 developmental biology, 030228 respiratory system, Toxicity, Immunology, Cytokines, Tobacco Smoke Pollution, business, Oxidative stress, Cigarette smoke (CS)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb66957f0da802fc8331573af7bb510
https://doi.org/10.1007/s00204-021-03008-0

المؤلفون: Marko Manevski, Dinesh Devadoss, Christopher Long, Shashi P. Singh, Mohd Wasim Nasser, Glen M. Borchert, Madhavan N. Nair, Irfan Rahman, Mohan Sopori, Hitendra S. Chand

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, bronchial epithelial cells, cigarette smoke (CS), chronic obstructive pulmonary disease (COPD), long noncoding RNA (lncRNA), mucus hyperexpression, lncRNA antisense to ICAM-1 (LASI)

Relation: https://figshare.com/articles/dataset/DataSheet_1_Increased_Expression_of_LASI_lncRNA_Regulates_the_Cigarette_Smoke_and_COPD_Associated_Airway_Inflammation_and_Mucous_Cell_Hyperplasia_docx/20448519

الاتاحة: https://doi.org/10.3389/fimmu.2022.803362.s001
https://figshare.com/articles/dataset/DataSheet_1_Increased_Expression_of_LASI_lncRNA_Regulates_the_Cigarette_Smoke_and_COPD_Associated_Airway_Inflammation_and_Mucous_Cell_Hyperplasia_docx/20448519

المؤلفون: Wande Li, Jing Zhou, Lijun Chen, Zhijun Luo, Yinzhi Zhao

المصدر: International Journal of Environmental Research and Public Health; Volume 8; Issue 1; Pages: 161-184

مصطلحات موضوعية: cigarette smoke (CS), CS condensate (CSC), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), cadmium (Cd), lysyl oxidase (LO), emphysema, carcinogenesis

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/ijerph8010161

الاتاحة: https://doi.org/10.3390/ijerph8010161

المؤلفون: E Li, Jing Zhou, Lijun Chen, Zhijun Luo, Yinzhi Zhao

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/a6/4c/Int_J_Environ_Res_Public_Health_2011_Jan_19_8(1)_161-184.tar.gz

مصطلحات موضوعية: cigarette smoke (CS, CS condensate (CSC, 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanone (NNK, cadmium (Cd, lysyl oxidase (LO, emphysema, carcinogenesis

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.293.3316

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.293.3316

المؤلفون: Steven P. Cass (11440021), Olivia Mekhael (11440024), Danya Thayaparan (10173586), Joshua J. C. McGrath (11440027), Spencer D. Revill (11440030), Matthew F. Fantauzzi (11440033), Peiyao Wang (4116649), Amir Reihani (11440036), Aaron I. Hayat (11440039), Christopher S. Stevenson (10173588), Anna Dvorkin-Gheva (201099), Fernando M. Botelho (7368626), Martin R. Stämpfli (11440042), Kjetil Ask (91350)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, macrophage, cigarette smoke (CS), immunopathology, tissue remodelling, fibrogenesis

Relation: https://figshare.com/articles/figure/Image_1_Increased_Monocyte-Derived_CD11b_Macrophage_Subpopulations_Following_Cigarette_Smoke_Exposure_Are_Associated_With_Impaired_Bleomycin-Induced_Tissue_Remodelling_tif/16626847

الاتاحة: https://doi.org/10.3389/fimmu.2021.740330.s001

المؤلفون: Steven P. Cass (11440021), Olivia Mekhael (11440024), Danya Thayaparan (10173586), Joshua J. C. McGrath (11440027), Spencer D. Revill (11440030), Matthew F. Fantauzzi (11440033), Peiyao Wang (4116649), Amir Reihani (11440036), Aaron I. Hayat (11440039), Christopher S. Stevenson (10173588), Anna Dvorkin-Gheva (201099), Fernando M. Botelho (7368626), Martin R. Stämpfli (11440042), Kjetil Ask (91350)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, macrophage, cigarette smoke (CS), immunopathology, tissue remodelling, fibrogenesis

Relation: https://figshare.com/articles/dataset/Table_1_Increased_Monocyte-Derived_CD11b_Macrophage_Subpopulations_Following_Cigarette_Smoke_Exposure_Are_Associated_With_Impaired_Bleomycin-Induced_Tissue_Remodelling_docx/16626865

الاتاحة: https://doi.org/10.3389/fimmu.2021.740330.s007

المؤلفون: Steven P. Cass, Olivia Mekhael, Danya Thayaparan, Joshua J. C. McGrath, Spencer D. Revill, Matthew F. Fantauzzi, Peiyao Wang, Amir Reihani, Aaron I. Hayat, Christopher S. Stevenson, Anna Dvorkin-Gheva, Fernando M. Botelho, Martin R. Stämpfli, Kjetil Ask

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, macrophage, cigarette smoke (CS), immunopathology, tissue remodelling, fibrogenesis

Relation: https://figshare.com/articles/dataset/Table_3_Increased_Monocyte-Derived_CD11b_Macrophage_Subpopulations_Following_Cigarette_Smoke_Exposure_Are_Associated_With_Impaired_Bleomycin-Induced_Tissue_Remodelling_docx/16626871

الاتاحة: https://doi.org/10.3389/fimmu.2021.740330.s009
https://figshare.com/articles/dataset/Table_3_Increased_Monocyte-Derived_CD11b_Macrophage_Subpopulations_Following_Cigarette_Smoke_Exposure_Are_Associated_With_Impaired_Bleomycin-Induced_Tissue_Remodelling_docx/16626871

المؤلفون: Department of Physiology, University of Florida, Gainesville, FL 32610, USA ( host institution ), Bose, Mahuya ( author ), Whittal, Randy M. ( author ), Gairola, C. Gary ( author ), Bose, Himangshu S. ( author )

مصطلحات موضوعية: Steroidogenesis, Steroidogenic acute regulatory protein (StAR), P450scc, Pregnenolone, Progesterone, Cigarette smoke (CS), Western blot

وصف الملف: Pages 284-290

Relation: Toxicology and Applied Pharmacology; S0041-008X(07)00481-4; http://ufdc.ufl.edu/LS00510491/00001

الاتاحة: https://doi.org/10.1016/j.taap.2007.10.021
http://ufdc.ufl.edu/LS00510491/00001

المؤلفون: Bartosz Pilecki, Helle Wulf-Johansson, Christian Støttrup, Patricia Troest Jørgensen, Pascal Djiadeu, Anders Bathum Nexøe, Anders Schlosser, Søren Werner Karlskov Hansen, Jens Madsen, Howard William Clark, Claus Henrik Nielsen, Jørgen Vestbo, Nades Palaniyar, Uffe Holmskov, Grith Lykke Sorensen

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, surfactant protein D (SP-D), cigarette smoke (CS), mouse models, ceramide, ceramide synthase

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Surfactant_Protein_D_Deficiency_Aggravates_Cigarette_Smoke-Induced_Lung_Inflammation_by_Upregulation_of_Ceramide_Synthesis_docx/7476818

الاتاحة: https://doi.org/10.3389/fimmu.2018.03013.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Surfactant_Protein_D_Deficiency_Aggravates_Cigarette_Smoke-Induced_Lung_Inflammation_by_Upregulation_of_Ceramide_Synthesis_docx/7476818

المؤلفون: Bartosz Pilecki, Helle Wulf-Johansson, Christian Støttrup, Patricia Troest Jørgensen, Pascal Djiadeu, Anders Bathum Nexøe, Anders Schlosser, Søren Werner Karlskov Hansen, Jens Madsen, Howard William Clark, Claus Henrik Nielsen, Jørgen Vestbo, Nades Palaniyar, Uffe Holmskov, Grith Lykke Sorensen

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, surfactant protein D (SP-D), cigarette smoke (CS), mouse models, ceramide, ceramide synthase

Relation: https://figshare.com/articles/figure/Image_2_Surfactant_Protein_D_Deficiency_Aggravates_Cigarette_Smoke-Induced_Lung_Inflammation_by_Upregulation_of_Ceramide_Synthesis_TIF/7476824

الاتاحة: https://doi.org/10.3389/fimmu.2018.03013.s003
https://figshare.com/articles/figure/Image_2_Surfactant_Protein_D_Deficiency_Aggravates_Cigarette_Smoke-Induced_Lung_Inflammation_by_Upregulation_of_Ceramide_Synthesis_TIF/7476824

المؤلفون: Mario Alberto Burgos-Aceves, Amit Cohen, Yoav Smith

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Pharmacology, medicine.disease_cause, 03 medical and health sciences, microRNA (miRNA), 0302 clinical medicine, microRNA, medicine, estrogen, Cigarette smoke, Lung cancer, Psychological repression, lung cancer (LC), Cruciferous vegetables, business.industry, Cigarette-smoke (CS), Cancer, Mini-Review, medicine.disease, respiratory tract diseases, 030104 developmental biology, Oncology, Estrogen, 030220 oncology & carcinogenesis, Cancer research, Carcinogenesis, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15046d551374b667f56cba479b5174d6
https://hdl.handle.net/20.500.12530/42648