المؤلفون: Sharma, Deepti, Lau, Evan, Qin, Yu, Jee, Kathleen, Rodrigues, Murilo, Guo, Chuanyu, Dinabandhu, Aumreetam, McIntyre, Emma, Salman, Shaima, Hwang, Yousang, Moshiri, Ala, Semenza, Gregg, Montaner, Silvia, Sodhi, Akrit

المصدر: Proceedings of the National Academy of Sciences. 121(46)

مصطلحات موضوعية: age-related macular degeneration, angiopoietin-like 4, choroidal neovascularization, hypoxia inducible factor, vascular endothelial growth factor, Animals, Humans, Receptors, Vascular Endothelial Growth Factor, Angiopoietin-Like Protein 4, Retinal Pigment Epithelium, Vascular Endothelial Growth Factor A, Hypoxia-Inducible Factor 1, alpha Subunit, Mice, Recombinant Fusion Proteins, Choroidal Neovascularization, Wet Macular Degeneration, Angiogenesis Inhibitors, Gene Expression Regulation, Male, Female

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/53x6n7tz
https://escholarship.org/content/qt53x6n7tz/qt53x6n7tz.pdf

المؤلفون: REGENXBIO Inc.

المصدر: A Randomized, Partially Masked, Controlled, Phase 2b/3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants With nAMD (ATMOSPHERE)

المصدر: A Phase III, Multicenter, Randomized, Double-Masked, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic Myopia

المصدر: A Two-year, Randomized, Double-masked, Multicenter, Two-arm Study Comparing the Efficacy and Safety of RTH258 6 mg Versus Aflibercept in Subjects With Neovascular Age-related Macular Degeneration
Singh RP, Jhaveri C, Wykoff CC, Gale RP, Staurenghi G, Iida T, Koh A, B G, Gedif K, Singer M. Efficacy Outcomes of Brolucizumab Versus Aflibercept in Neovascular Age-Related Macular Degeneration Patients with Early Residual Fluid. Ophthalmol Retina. 2022 May;6(5):377-386. doi: 10.1016/j.oret.2021.12.014. Epub 2021 Dec 27.
Mones J, Srivastava SK, Jaffe GJ, Tadayoni R, Albini TA, Kaiser PK, Holz FG, Korobelnik JF, Kim IK, Pruente C, Murray TG, Heier JS. Risk of Inflammation, Retinal Vasculitis, and Retinal Occlusion-Related Events with Brolucizumab: Post Hoc Review of HAWK and HARRIER. Ophthalmology. 2021 Jul;128(7):1050-1059. doi: 10.1016/j.ophtha.2020.11.011. Epub 2020 Nov 15.
Dugel PU, Koh A, Ogura Y, Jaffe GJ, Schmidt-Erfurth U, Brown DM, Gomes AV, Warburton J, Weichselberger A, Holz FG; HAWK and HARRIER Study Investigators. HAWK and HARRIER: Phase 3, Multicenter, Randomized, Double-Masked Trials of Brolucizumab for Neovascular Age-Related Macular Degeneration. Ophthalmology. 2020 Jan;127(1):72-84. doi: 10.1016/j.ophtha.2019.04.017. Epub 2019 Apr 12.

المصدر: A Two-Year, Randomized, Double-Masked, Multicenter, Three-Arm Study Comparing the Efficacy and Safety of RTH258 Versus Aflibercept in Subjects With Neovascular Age-Related Macular Degeneration
Singh RP, Jhaveri C, Wykoff CC, Gale RP, Staurenghi G, Iida T, Koh A, B G, Gedif K, Singer M. Efficacy Outcomes of Brolucizumab Versus Aflibercept in Neovascular Age-Related Macular Degeneration Patients with Early Residual Fluid. Ophthalmol Retina. 2022 May;6(5):377-386. doi: 10.1016/j.oret.2021.12.014. Epub 2021 Dec 27.
Mones J, Srivastava SK, Jaffe GJ, Tadayoni R, Albini TA, Kaiser PK, Holz FG, Korobelnik JF, Kim IK, Pruente C, Murray TG, Heier JS. Risk of Inflammation, Retinal Vasculitis, and Retinal Occlusion-Related Events with Brolucizumab: Post Hoc Review of HAWK and HARRIER. Ophthalmology. 2021 Jul;128(7):1050-1059. doi: 10.1016/j.ophtha.2020.11.011. Epub 2020 Nov 15.
Dugel PU, Koh A, Ogura Y, Jaffe GJ, Schmidt-Erfurth U, Brown DM, Gomes AV, Warburton J, Weichselberger A, Holz FG; HAWK and HARRIER Study Investigators. HAWK and HARRIER: Phase 3, Multicenter, Randomized, Double-Masked Trials of Brolucizumab for Neovascular Age-Related Macular Degeneration. Ophthalmology. 2020 Jan;127(1):72-84. doi: 10.1016/j.ophtha.2019.04.017. Epub 2019 Apr 12.

المساهمون: Wong Ho Daniel Tak, Principal Investigator

المصدر: Faricimab Fixed Quarterly Maintenance for Neovascular Age Related Macular Degeneration: A Prospective Case Series
Wong DHT, Li KKW. Fixed Quarterly Dosing of Aflibercept after Loading Doses in Neovascular Age-Related Macular Degeneration in Chinese Eyes. J Clin Med. 2023 Dec 27;13(1):145. doi: 10.3390/jcm13010145.
Heier JS, Khanani AM, Quezada Ruiz C, Basu K, Ferrone PJ, Brittain C, Figueroa MS, Lin H, Holz FG, Patel V, Lai TYY, Silverman D, Regillo C, Swaminathan B, Viola F, Cheung CMG, Wong TY; TENAYA and LUCERNE Investigators. Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials. Lancet. 2022 Feb 19;399(10326):729-740. doi: 10.1016/S0140-6736(22)00010-1. Epub 2022 Jan 24.
Wong WL, Su X, Li X, Cheung CM, Klein R, Cheng CY, Wong TY. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis. Lancet Glob Health. 2014 Feb;2(2):e106-16. doi: 10.1016/S2214-109X(13)70145-1. Epub 2014 Jan 3.
Ambati J, Fowler BJ. Mechanisms of age-related macular degeneration. Neuron. 2012 Jul 12;75(1):26-39. doi: 10.1016/j.neuron.2012.06.018.

المؤلفون: Fondo de Investigacion Sanitaria

المصدر: Phase III Study of Efficacy and Safety of Intravitreal Bevacizumab in the Treatment of Choroidal Neovascular Membranes Associated to High Myopia

المؤلفون: National Eye Institute (NEI)

المساهمون: Monika Fleckenstein, Professor

المصدر: The Impact of Non-Exudative Type 1 Macular Neovascularization (MNV) on Age-related Macular Degeneration (AMD) Progression

المؤلفون: CROlife

المصدر: Multicentre Randomized Double-blind Trial of VISUPRIME® Eye Drops to be Evaluated in Preventing the Conjunctival Bacterial Load in Patients Undergoing to Anti-VEGF Injection

المؤلفون: Jingxiang Zhang, Xia Sheng, Quanju Ding, Yujun Wang, Jiwei Zhao, Jingfa Zhang

المصدر: Neural Regeneration Research, Vol 20, Iss 2, Pp 378-393 (2025)

مصطلحات موضوعية: choroidal neovascularization, epithelial-mesenchymal transition, mesenchymal transition, myofibroblast, neovascular age-related macular degeneration, submacular fibrosis, subretinal fibrosis, therapeutic targets, transforming growth factor-β, vascular endothelial growth factor, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://journals.lww.com/10.4103/NRR.NRR-D-23-01642; https://doaj.org/toc/1673-5374; https://doaj.org/toc/1876-7958

URL الوصول: https://doaj.org/article/55d622bf77d54feea1f83b7954f87264

المؤلفون: Bei Xiao, Yanping Song, Ming Yan, Ya Ye, Zhen Huang

المصدر: Scientific Reports, Vol 15, Iss 1, Pp 1-11 (2025)

مصطلحات موضوعية: Pachychoroid spectrum diseases (PSD), Choroid, Ultra-widefield swept-source optical coherence tomography angiography (UWF SS-OCTA), Vortex veins, Choroidal neovascularization, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/a554dd2337f446ab827b7b4ea04e2fb8

المؤلفون: Rush RB, Klein W, Rush SW, Reinauer R

المصدر: Clinical Ophthalmology, Vol Volume 19, Pp 111-118 (2025)

مصطلحات موضوعية: geographic atrophy, avacincaptad pegol, macular neovascularization, izervay, choroidal neovascularization, complement inhibition, age-related macular degeneration, Ophthalmology, RE1-994

وصف الملف: electronic resource

Relation: https://www.dovepress.com/one-year-outcomes-in-subjects-developing-macular-neovascularization-wh-peer-reviewed-fulltext-article-OPTH; https://doaj.org/toc/1177-5483

URL الوصول: https://doaj.org/article/6df03a920ec3470eaaf42c11638f1919

المؤلفون: Hee Yong Han, Sang Min Park, Ji Hyun Lee, Chul Gu Kim, Jong Woo Kim, Han Joo Cho, Jae Hui Kim

المصدر: Scientific Reports, Vol 15, Iss 1, Pp 1-10 (2025)

مصطلحات موضوعية: Age-related macular degeneration, Choroidal neovascularization, Faricimab, Macular neovascularization, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/54e69bef2a0740b6bd45254192750175

المؤلفون: Inês Costa, Ana Carvalho, Helton Andrade, Bruno Pereira, Pedro Camacho

المصدر: International Journal of Ophthalmology, Vol 18, Iss 1, Pp 103-110 (2025)

مصطلحات موضوعية: age-related macular degeneration, ganglion cell complex, choroid, geographic atrophy, choroidal neovascularization, spectral domain optical coherence tomography, Ophthalmology, RE1-994

وصف الملف: electronic resource

Relation: http://ies.ijo.cn/en_publish/2025/1/20250112.pdf; https://doaj.org/toc/2222-3959; https://doaj.org/toc/2227-4898

URL الوصول: https://doaj.org/article/e30cfb8b2b3b40a686d5fafb73da59c0

المؤلفون: Zhang Yichi, Yang Xiuxia, Liu Pingping, Liu Mengjie, Luo Wenting, Liu Yang, Yang Chengcheng

المصدر: Guoji Yanke Zazhi, Vol 24, Iss 12, Pp 1863-1872 (2024)

مصطلحات موضوعية: microglia polarization, choroidal neovascularization, inflammation, oxidative stress, macular degeneration, Ophthalmology, RE1-994

وصف الملف: electronic resource

Relation: http://ies.ijo.cn/cn_publish/2024/12/202412002.pdf; https://doaj.org/toc/1672-5123

URL الوصول: https://doaj.org/article/9e52db4adce543b7b75e7bc774e3f1de

المؤلفون: Badal Lafulla, Josep

المساهمون: University/Department: Universitat Autònoma de Barcelona. Departament de Cirurgia

Thesis Advisors: Zapata Victori, Miguel Ángel, García-Arumí, José

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Degeneració maculada associada a l'edat, Degeneracón macular asociada a la edad, Age-related macular degeneration, PEDF (Pigment epithelium derived Factor), Neovascularitzxació coroidea, Neovascularización coroidea, Choroidal neovascularization, Ciències de la Salut

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/370858

المؤلفون: Roubeix, Christophe, Nous, Caroline, Augustin, Sébastien, Ronning, Kaitryn, Mathis, Thibaud, Blond, Frédéric, Lagouge-Roussey, Pauline, Crespo-Garcia, Sergio, Sullivan, Patrick, Gautier, Emmanuel, Reichhart, Nadine, Sahel, José-Alain, Burns, Marie, Paques, Michel, Sørensen, Torben, Strauss, Olaf, Guillonneau, Xavier, Delarasse, Cécile, Sennlaub, Florian

المصدر: Journal of Neuroinflammation. 21(1)

مصطلحات موضوعية: Age-related macular degeneration, Angiotensin, Neuroinflammation, Splenic monocytes, Humans, Mice, Animals, Aged, Monocytes, Angiotensin II, Macular Degeneration, Inflammation, Choroidal Neovascularization

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/84q70858
https://escholarship.org/content/qt84q70858/qt84q70858.pdf

المؤلفون: Deussen, Daniel N, Heinke, Anna, Elsner, Wyatt, Galang, Carlo Miguel B, Kalaw, Fritz Gerald P, Warter, Alexandra, Bartsch, Dirk-Uwe, Cheng, Lingyun, Freeman, William R

المصدر: Scientific Reports. 14(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Ophthalmology and Optometry, Eye Disease and Disorders of Vision, Neurodegenerative, Neurosciences, Macular Degeneration, Aging, Biomedical Imaging, Bioengineering, Eye, Humans, Choroidal Neovascularization, Tomography, Optical Coherence, Female, Male, Retrospective Studies, Aged, Aged, 80 and over, Image Processing, Computer-Assisted, Middle Aged, Fluorescein Angiography

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/89z5d5s5
https://escholarship.org/content/qt89z5d5s5/qt89z5d5s5.pdf

المصدر: OCT, Visual Outcome and Angiographic Analysis of Choroidal Neovascularization in Six Eyes With Angioid Streaks Treated With a Single Intravitreal Injection of Bevacizumab