المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/journal_contribution/S1_Checklist_-/19118285

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.s001

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/journal_contribution/Western_blot_raw_images_for_Fig_8_/19118294

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.s003

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/journal_contribution/S1_Protocol_-/19118297

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.s004

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/figure/Nitric_Oxide_levels_inferred_from_nitrate_plus_nitrite_levels_in_neutrophil_lysates_/19118315

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.g006

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/dataset/Genes_which_showed_changes_in_expression_after_administration_IFN-_over_time_or_dose_/19118288

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.s002

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/figure/Fig_1_-/19118300

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.g001

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/figure/Fig_2_-/19118303

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.g002

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/figure/Examples_of_gene_expression_changes_in_response_to_IFN-_administration_/19118309

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.g004

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/figure/Heat_map_showing_time_dependent_changes_for_all_genes_with_a_2-fold_maximal_increase_or_decrease_in_gene_expression_mRNA_in_response_to_single_doses_of_IFN-_/19118306

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.g003

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/figure/Tetahydrobiopterin_BH4_levels_in_neutrophil_lysates_/19118321

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.g007

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/figure/Western_blot_analysis_for_selected_proteins_/19118324

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.g008

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/dataset/Pathways_analysis_applied_to_the_gene_expression_changes_induced_by_IFN-_in_neutrophils_of_healthy_subjects_/19118330

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.t002

المؤلفون: Daniel R. Ambruso (12042605), Natalie J. Briones (12042608), Angelina F. Baroffio (12042611), John R. Murphy (2695960), Alexander D. Tran (12042614), Katherine Gowan (477831), Bridget Sanford (8942933), Michael Ellison (5820), Kenneth L. Jones (183018)

مصطلحات موضوعية: Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Immunology, Mental Health, Infectious Diseases, generating nadph oxidase, expand therapeutic applications, essential nos cofactor, div >< p, could provide strategies, chronic granulomatous disease, also enhances functions, administered varying doses, gamma induced changes, changes occurred rapidly, guanylate binding proteins, circulating pmn number, pmns exhibited dose, plasma drug levels, neutrophil host defense, adaptive immune system, several genes involved, proteins involved, coordinate changes, protein levels, pmn ), plasma concentrations

Relation: https://figshare.com/articles/dataset/Functionally_relevant_neutrophil_genes_that_were_altered_by_IFN-_administration_to_healthy_subjects_/19118327

الاتاحة: https://doi.org/10.1371/journal.pone.0263370.t001