المؤلفون: Alexander K. Hurben (9021467), Luke N. Erber (9388398), Natalia Y. Tretyakova (1330866), Todd M. Doran (1321890)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, midbrain dopaminergic neurons, fluorescent reporter molecule, enabled global mapping, electrophilic dopaquinone species, critical first step, cellular targets modified, biorthogonal alkyne handle, sy5y cells indicates, metabolic quinone toxicity, compelling evidence suggests, linking dpas formed, dpas generated reproducibly, yne , reactivity profile similar, pd remain unclear, induces neuronal stress, improper da sequestration, dopamine metabolites using, cellular proteins affected, exacerbate er stress, er stress pathway

Relation: https://figshare.com/articles/journal_contribution/Proteome-Wide_Profiling_of_Cellular_Targets_Modified_by_Dopamine_Metabolites_Using_a_Bio-Orthogonally_Functionalized_Catecholamine/16920155

الاتاحة: https://doi.org/10.1021/acschembio.1c00629.s001