المؤلفون: Andreas Kunzendorf (6251591), Guangcai Xu (8839523), Jesse J. H. van der Velde (11571121), Henriëtte J. Rozeboom (2885936), Andy-Mark W. H. Thunnissen (8448201), Gerrit J. Poelarends (1264938)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Biotechnology, Evolutionary Biology, Sociology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, derived catalysts inspired, crystallographic analysis provides, carried 12 amino, based mechanism ), high catalytic efficiency, abiological reaction makes, catalytic activity compared, found extensive application, explore iminium catalysis, aldolase acts naturally, redesigned dera enzyme, directed evolution class, directed evolution, catalytic repertoire, reaction scope, instead acts, evolved activity, work demonstrates, wildtype enzyme, unsaturated aldehydes

Relation: https://figshare.com/articles/journal_contribution/Unlocking_Asymmetric_Michael_Additions_in_an_Archetypical_Class_I_Aldolase_by_Directed_Evolution/16821190

الاتاحة: https://doi.org/10.1021/acscatal.1c03911.s001