المؤلفون: Joergensen, Steen Hylgaard, Hansen, Esben Soevsoe S., Bøgh, Nikolaj, Bertelsen, Lotte Bonde, Tougaard, Rasmus Stilling, Staehr, Peter Bisgaard, Laustsen, Christoffer, Wiggers, Henrik

المصدر: Joergensen , S H , Hansen , E S S , Bøgh , N , Bertelsen , L B , Tougaard , R S , Staehr , P B , Laustsen , C & Wiggers , H 2024 , ' Hyperpolarized [1- 13 C]pyruvate cardiovascular magnetic resonance imaging identifies metabolic phenotypes in patients with heart failure ' , Journal of Cardiovascular Magnetic Resonance , vol. 26 , no. 2 , 101095 . https://doi.org/10.1016/j.jocmr.2024.101095

مصطلحات موضوعية: Cardiac metabolism, Heart failure, Hyperpolarized [1-C]pyruvate magnetic resonance imaging, Metabolic imaging, Hyperpolarized [1- C]pyruvate magnetic resonance imaging

وصف الملف: application/pdf

الاتاحة: https://vbn.aau.dk/da/publications/9bee3898-3374-4086-a533-e34f96331e3a
https://doi.org/10.1016/j.jocmr.2024.101095
https://vbn.aau.dk/ws/files/754674730/Joergensen_et_al._2024_._Hyperpolarized_1-13C_pyruvate_cardiovascular_magnetic_resonance_imaging_identifies_metabolic_phenotypes_in_patients_with_heart_failure.pdf
http://www.scopus.com/inward/record.url?scp=85210059782&partnerID=8YFLogxK

المؤلفون: Hansen, Kasper, Hansen, Esben Søvsø S, Jespersen, Nichlas Riise V, Bøtker, Hans Erik, Pedersen, Michael, Wang, Tobias, Laustsen, Christoffer

المصدر: Hansen , K , Hansen , E S S , Jespersen , N R V , Bøtker , H E , Pedersen , M , Wang , T & Laustsen , C 2022 , ' Hyperpolarized 13 C MRI Reveals Large Changes in Pyruvate Metabolism During Digestion in Snakes ' , Magnetic Resonance in Medicine , vol. 88 , no. 2 , pp. 890-900 . https://doi.org/10.1002/mrm.29239

مصطلحات موضوعية: MRI, [1- C]pyruvate, metabolism, postprandial, python, reptile

Relation: https://pure.au.dk/portal/en/publications/24834398-9335-475c-91d8-c4fac9c22cce

الاتاحة: https://pure.au.dk/portal/en/publications/24834398-9335-475c-91d8-c4fac9c22cce
https://doi.org/10.1002/mrm.29239
http://www.scopus.com/inward/record.url?scp=85129035570&partnerID=8YFLogxK
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321735/pdf/MRM-88-890.pdf

المؤلفون: Joao Piraquive Agudelo, Deepti Upadhyay, Dalin Zhang, Hongjuan Zhao, Rosalie Nolley, Jinny Sun, Shubhangi Agarwal, Robert A. Bok, Daniel B. Vigneron, James D. Brooks, John Kurhanewicz, Donna M. Peehl, Renuka Sriram

المصدر: Metabolites; Volume 12; Issue 11; Pages: 1117

مصطلحات موضوعية: renal cell carcinoma, patient-derived xenografts, magnetic resonance imaging, hyperpolarized [1- 13 C]pyruvate, metabolism

وصف الملف: application/pdf

Relation: Endocrinology and Clinical Metabolic Research; https://dx.doi.org/10.3390/metabo12111117

الاتاحة: https://doi.org/10.3390/metabo12111117

المؤلفون: Martin Grashei, Philipp Biechl, Franz Schilling, Angela M. Otto

المصدر: Cancers; Volume 14; Issue 7; Pages: 1845

مصطلحات موضوعية: breast cancer cells, 13 C-glucose metabolomics, hyperpolarized 13 C-pyruvate, glycolysis, LDH, nutrient deprivation, pyruvate kinase, TCA-cycle, compartmentation, Warburg effect

وصف الملف: application/pdf

Relation: Tumor Microenvironment; https://dx.doi.org/10.3390/cancers14071845

الاتاحة: https://doi.org/10.3390/cancers14071845

المؤلفون: Shivanand Pudakalakatti, Mark Titus, José S. Enriquez, Sumankalai Ramachandran, Niki M. Zacharias, Imad Shureiqi, Yi Liu, James C. Yao, Xiangsheng Zuo, Pratip K. Bhattacharya

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1645

مصطلحات موضوعية: gastric cancer, PPARD, NMR spectroscopy, LC-MS, hyperpolarized [1- 13 C] pyruvate MR spectroscopy, metabolomics, metabolites, metabolic imaging

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms23031645

الاتاحة: https://doi.org/10.3390/ijms23031645

المؤلفون: Patrick TomHon (11872610), Mustapha Abdulmojeed (11872613), Isaiah Adelabu (11872616), Shiraz Nantogma (10098106), Mohammad Shah Hafez Kabir (11872619), Sören Lehmkuhl (11872622), Eduard Y. Chekmenev (1290312), Thomas Theis (1358547)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Biotechnology, Ecology, Cancer, Physical Sciences not elsewhere classified, temperature cycling method, requires significant infrastructure, positron emission tomography, emerging nonionizing alternative, characterizes critical relaxation, scalable hyperpolarization technique, inexpensive hyperpolarization methods, cost mri systems, 13 , c pyruvate images, c ]- pyruvate, 1 -< sup, vivo <, hyperpolarized mri, free pyruvate, bound pyruvate, sheath hyperpolarization, ≈ 20, signal amplification, reversible exchange, lower temperatures, kinetic model

Relation: https://figshare.com/articles/journal_contribution/Temperature_Cycling_Enables_Efficient_sup_13_sup_C_SABRE-SHEATH_Hyperpolarization_and_Imaging_of_1-_sup_13_sup_C_-Pyruvate/17429927

الاتاحة: https://doi.org/10.1021/jacs.1c09581.s001

المؤلفون: Martin Grashei, Christian Hundshammer, Frits H. A. van Heijster, Geoffrey J. Topping, Franz Schilling

المصدر: Pharmaceuticals; Volume 14; Issue 4; Pages: 327

مصطلحات موضوعية: T 2 relaxation time constant, pH, [1- 13 C]pyruvate, [1- 13 C]acetate, 13 C-labeled biomolecules, hyperpolarization, hyperpolarized MRI, magnetic resonance spectroscopy

وصف الملف: application/pdf

Relation: Radiopharmaceutical Sciences; https://dx.doi.org/10.3390/ph14040327

الاتاحة: https://doi.org/10.3390/ph14040327

المؤلفون: Jinny Sun, Robert A. Bok, Justin DeLos Santos, Deepti Upadhyay, Romelyn DeLos Santos, Shubhangi Agarwal, Mark Van Criekinge, Daniel B. Vigneron, Rahul Aggarwal, Donna M. Peehl, John Kurhanewicz, Renuka Sriram

المصدر: Metabolites; Volume 11; Issue 3; Pages: 139

مصطلحات موضوعية: metabolism, prostate cancer, castration-resistant, androgen-dependent, TRAMP, magnetic resonance, hyperpolarized [1- 13 C]pyruvate, lactate, glycolysis

وصف الملف: application/pdf

Relation: Metabolomic Profiling Technology; https://dx.doi.org/10.3390/metabo11030139

الاتاحة: https://doi.org/10.3390/metabo11030139

المؤلفون: Gal Sapir, Daniel J. Steinberg, Rami I. Aqeilan, Rachel Katz-Brull

المصدر: Pharmaceuticals, Vol 14, Iss 878, p 878 (2021)

مصطلحات موضوعية: organoids, dissolution dynamic nuclear polarization, lactate dehydrogenase, [1- 13 C]pyruvate, Medicine, Pharmacy and materia medica, RS1-441

Relation: https://www.mdpi.com/1424-8247/14/9/878; https://doaj.org/toc/1424-8247; https://doaj.org/article/19b3e5554cc44d159849ea60642ea83d

الاتاحة: https://doi.org/10.3390/ph14090878
https://doaj.org/article/19b3e5554cc44d159849ea60642ea83d

المؤلفون: Ros, Susana, Wright, Alan J, D'Santos, Paula, Hu, De-En, Hesketh, Richard L, Lubling, Yaniv, Georgopoulou, Dimitra, Lerda, Giulia, Couturier, Dominique-Laurent, Razavi, Pedram, Pelossof, Rapahel, Batra, Ankita S, Mannion, Elizabeth, Lewis, David Y, Martin, Alistair, Baird, Richard D, Oliveira, Mafalda, de Boo, Leonora W, Linn, Sabine C, Scaltriti, Maurizio, Rueda, Oscar M, Bruna, Alejandra, Caldas, Carlos, Brindle, Kevin M

مصطلحات موضوعية: FDG-PET, FOXM1, MRI, PI3K alpha inhibition, biomarker, breast cancer, hexokinase 2, hyperpolarized [1-(13)C]pyruvate, lactate dehydrogenase, treatment response, Animals, Antineoplastic Combined Chemotherapy Protocols, Breast Neoplasms, Cell Line, Tumor, Class I Phosphatidylinositol 3-Kinases, Drug Resistance, Neoplasm, Female, Forkhead Box Protein M1, Fulvestrant, Humans, Imidazoles, MCF-7 Cells, Magnetic Resonance Imaging, Mice, Inbred NOD, Knockout, SCID, Oxazepines

وصف الملف: Print-Electronic; application/pdf

Relation: https://doi.org/10.17863/CAM.55683; https://doi.org/10.17863/CAM.62058; https://www.repository.cam.ac.uk/handle/1810/309812

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/309812
https://doi.org/10.17863/CAM.56911

المؤلفون: Mette Hauge Lauritzen, Peter Magnusson, Christoffer Laustsen, Sadia Asghar Butt, Jan Henrik Ardenkjær-Larsen, Lise Vejby Søgaard, Olaf B. Paulson, Per Åkeson

المصدر: Tomography; Volume 3; Issue 3; Pages: 123-130

مصطلحات موضوعية: magnetic resonance imaging, cardiac metabolism, ischemic heart disease, myocardial infarction, hyperpolarized 13 C pyruvate, rat model

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.18383/j.tom.2017.00008

الاتاحة: https://doi.org/10.18383/j.tom.2017.00008

المؤلفون: Henrik Gutte, Adam Hansen, Majbrit Larsen, Sofie Rahbek, Helle Johannesen, Jan Ardenkjaer-Larsen, Annemarie Kristensen, Liselotte Højgaard, Andreas Kjaer

المصدر: Diagnostics; Volume 5; Issue 3; Pages: 287-289

مصطلحات موضوعية: cancer, dynamic nuclear polarization, hyperpolarized, 13 C-pyruvate, MR, 18 F-FDG-PET, PET/MR, molecular imaging, hyperPET

وصف الملف: application/pdf

Relation: Medical Imaging and Theranostics; https://dx.doi.org/10.3390/diagnostics5030287

الاتاحة: https://doi.org/10.3390/diagnostics5030287

المؤلفون: Qi, Qi, Fox, Matthew S., Lim, Heeseung, Bartha, Robert, Scholl, Timothy J., Hoffman, Lisa, Lee, Ting Yim, Thiessen, Jonathan D.

المصدر: Medical Biophysics Publications

مصطلحات موضوعية: FDG-PET, Glioblastoma, glucoCEST, hyperpolarized [1- C]pyruvate 13, Tumor glycolysis, Tumor perfusion

Relation: https://ir.lib.uwo.ca/biophysicspub/585

الاتاحة: https://ir.lib.uwo.ca/biophysicspub/585
https://doi.org/10.1007/s11307-021-01585-1

المؤلفون: Stefan Neubauer, Kerstin N. Timm, Kieran Clarke, William Watson, Oliver J Rider, Yaso Emmanuel, Damian J. Tyler, Andrew Lewis, Miller Jjj.

المصدر: Watson, W D, Timm, K N, Lewis, A J, Miller, J J J, Emmanuel, Y, Clarke, K, Neubauer, S, Tyler, D J & Rider, O J 2020, ' Nicotinic acid receptor agonists impair myocardial contractility by energy starvation ', FASEB Journal, vol. 34, no. 11, pp. 14878-14891 . https://doi.org/10.1096/fj.202000084RR

مصطلحات موضوعية: 0301 basic medicine, Agonist, Adult, Male, medicine.medical_specialty, Acipimox, Phosphocreatine, medicine.drug_class, P MR spectroscopy, Pyruvate Dehydrogenase Complex, Carbohydrate metabolism, Biochemistry, Niacin, Receptors, G-Protein-Coupled, Contractility, 03 medical and health sciences, chemistry.chemical_compound, cardiac metabolism, 0302 clinical medicine, Adenosine Triphosphate, Internal medicine, Genetics, medicine, Animals, Humans, Insulin, Rats, Wistar, nicotinic acid, hyperpolarized C pyruvate, Molecular Biology, Hypolipidemic Agents, Ejection fraction, Chemistry, Heart, Pyruvate dehydrogenase complex, Myocardial Contraction, Rats, 030104 developmental biology, Nicotinic agonist, Endocrinology, Pyrazines, Carbohydrate Metabolism, Energy Metabolism, 030217 neurology & neurosurgery, Biotechnology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d007fec902340e6fc20a90b1c2739e31
https://doi.org/10.1096/fj.202000084rr

المؤلفون: De-En Hu, David Y. Lewis, Giulia Lerda, Carlos Caldas, Dominique-Laurent Couturier, Susana Ros, Alan J. Wright, Alejandra Bruna, Paula D'Santos, Maurizio Scaltriti, Yaniv Lubling, Richard L. Hesketh, Dimitra Georgopoulou, Rapahel Pelossof, Alistair Martin, Ankita Sati Batra, Oscar M. Rueda, Kevin M. Brindle, Leonora W. de Boo, Sabine C. Linn, Mafalda Oliveira, Pedram Razavi, Richard D. Baird, Elizabeth Mannion

المساهمون: Institut Català de la Salut, [Ros S, Wright AJ, D'Santos P, Hu DE, Hesketh RL, Lubling Y] Cancer Research UK Cambridge Institute and Department of Oncology, Li Ka Shing Centre, University of Cambridge, Cambridge, UK. Cancer Research UK Cambridge Cancer Centre, Cambridge, UK. [Oliveira M] Servei d’Oncologia Mèdica, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Scientia
Cancer Cell

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, PI3K alpha inhibition, Neoplasms::Neoplasms by Site::Breast Neoplasms [DISEASES], Estrogen receptor, Medicaments antineoplàstics - Ús terapèutic, Mice, SCID, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Mama - Càncer, Mice, Inbred NOD, Antineoplastic Combined Chemotherapy Protocols, Medicine, Other subheadings::/therapeutic use [Other subheadings], FDG-PET, Fulvestrant, Mice, Knockout, neoplasias::neoplasias por localización::neoplasias de la mama [ENFERMEDADES], medicine.diagnostic_test, Imidazoles, Glucose analog, Magnetic Resonance Imaging, hexokinase 2, Oncology, Receptors, Estrogen, Positron emission tomography, 030220 oncology & carcinogenesis, MCF-7 Cells, Biomarker (medicine), biomarker, Female, medicine.drug, MRI, Class I Phosphatidylinositol 3-Kinases, Breast Neoplasms, Article, 03 medical and health sciences, Breast cancer, breast cancer, Lactate dehydrogenase, Cell Line, Tumor, Animals, Humans, Lactic Acid, terapéutica::protocolos clínicos::protocolos antineoplásicos::protocolos de quimioterapia antineoplásica combinada [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], hyperpolarized [1-(13)C]pyruvate, Protein Kinase Inhibitors, Fluorodeoxyglucose, Oncogene, business.industry, Otros calificadores::/uso terapéutico [Otros calificadores], hyperpolarized [1-13C]pyruvate, Forkhead Box Protein M1, FOXM1, treatment response, lactate dehydrogenase, Therapeutics::Clinical Protocols::Antineoplastic Protocols::Antineoplastic Combined Chemotherapy Protocols [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], medicine.disease, Xenograft Model Antitumor Assays, Oxazepines, Tamoxifen, 030104 developmental biology, chemistry, Drug Resistance, Neoplasm, Cancer research, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b060b2e425bd30db0f56bcb62081cf
https://hdl.handle.net/11351/6311

المؤلفون: Wang, Zhimin, Nielsen, Per Mose, Laustsen, Christoffer, Bertelsen, Lotte Bonde

المصدر: Wang , Z , Nielsen , P M , Laustsen , C & Bertelsen , L B 2019 , ' Metabolic consequences of lactate dehydrogenase inhibition by oxamate in hyperglycemic proximal tubular cells ' , Experimental Cell Research , vol. 378 , no. 1 , pp. 51-56 . https://doi.org/10.1016/j.yexcr.2019.03.001

مصطلحات موضوعية: Hyperglycemia, Hyperpolarized [1- C]pyruvate, Metabolic flux, NMR, Oxamate, Proximal tubule cells

Relation: https://pure.au.dk/portal/en/publications/0ed04981-71b6-44e7-8000-8f7adc50000f

الاتاحة: https://pure.au.dk/portal/en/publications/0ed04981-71b6-44e7-8000-8f7adc50000f
https://doi.org/10.1016/j.yexcr.2019.03.001
http://www.scopus.com/inward/record.url?scp=85062394966&partnerID=8YFLogxK

المؤلفون: Charbel D. Assaf, Xin Gui, Alexander A. Auer, Simon B. Duckett, Jan-Bernd Hövener, Andrey N. Pravdivtsev

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Genetics, Neuroscience, Evolutionary Biology, Cancer, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, h –< sup, versatile hyperpolarization technique, spin order transfer, 13 , lived organometallic complexes, 1 hz enable, c signal gain, c pyruvate spins, 2 -< sup, 1 , c hyperpolarization, vivo <, spin topology, signal amplification, pyruvate case, j <, 69 hz, study demonstrates, spinept ), selective excitation

Relation: https://figshare.com/articles/journal_contribution/_i_J_i_Coupling_Constants_of_1_Hz_Enable_sup_13_sup_C_Hyperpolarization_of_Pyruvate_via_Reversible_Exchange_of_Parahydrogen/25062838

الاتاحة: https://doi.org/10.1021/acs.jpclett.3c02980.s007
https://figshare.com/articles/journal_contribution/_i_J_i_Coupling_Constants_of_1_Hz_Enable_sup_13_sup_C_Hyperpolarization_of_Pyruvate_via_Reversible_Exchange_of_Parahydrogen/25062838