المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/Clinical_and_immunological_patient_characteristics_/16629389

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s001

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/SARS-CoV-2_peptide_sequences_of_the_envelope-_membrane-_and_nucleoprotein_/16629395

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s002

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/Overview_of_SARS-CoV-2_envelope_protein-specific_CD4_T_cell_responses_in_patients_with_acute_and_resolved_COVID-19_/16629401

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s003

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/Overview_of_SARS-CoV-2_membrane_and_nucleoprotein-specific_CD8_T_cell_responses_in_acute_and_resolved_COVID-19_patients_/16629413

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s005

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/S8_Table_-/16629428

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s008

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/Sequence_homology_of_CCC_and_the_most_frequently_detected_SARS-CoV-2_epitopes_in_this_study_/16629416

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s006

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/Original_FACS-plots_of_restriction_assay_/16629455

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s013

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/Breadth_of_the_CD4_T_cell_response_against_the_SARS-CoV-2_envelope_membrane_and_nucleoprotein_of_patient_rCov-17_/16629443

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s011

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/S3_Fig_-/16629449

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s012

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/_i_Ex_vivo_i_ICS_with_PBMCs_of_six_acute_COVID-19_patients_after_stimulation_with_the_ten_most_frequently_detected_peptides_of_the_envelope_membrane_and_nucleoprotein_from_this_study_/16629461

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s014

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/S6_Fig_-/16629464

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.s015

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/The_envelope_membrane_and_nucleoprotein-specific_CD4_T_cell_response_/16629470

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.g001

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/Distribution_of_CD4_T_cell_responses_against_the_nucleo_membrane_and_envelope-protein_/16629488

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.g004

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/Overview_of_the_SARS-CoV-2_membrane_protein-specific_CD4_T_cell_responses_in_patients_with_acute_n_10_and_resolved_n_24_COVID-19_/16629482

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.g003

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/Overview_of_the_most_frequently_detected_peptides_of_the_SARS-CoV-2_membrane_protein_by_CD4_T_cells_in_the_current_study_/16629509

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.t003

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/Fine_mapping_of_the_most_frequently_detected_peptides_Mem_P30_aa146-160_Mem_P36_aa176-190_and_Ncl_P18_aa86-100_/16629491

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.g005

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/figure/The_i_ex_vivo_i_peptide-specific_CD4_T_cell_response_in_patient_rCov21_/16629494

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.g006

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/Clinical_and_immunological_patient_characteristics_of_acute_and_resolved_COVID-19_patients_/16629497

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.t001

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/Overview_of_the_most_frequently_detected_peptides_of_the_SARS-CoV-2_envelope_protein_by_CD4_T_cells_in_the_current_study_/16629512

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.t004

المؤلفون: Janna Heide (6494270), Sophia Schulte (9302936), Matin Kohsar (11441921), Thomas Theo Brehm (9302939), Marissa Herrmann (9302933), Hendrik Karsten (11441924), Matthias Marget (8343447), Sven Peine (3545648), Alexandra M. Johansson (11441927), Alessandro Sette (19132), Marc Lütgehetmann (6807842), William W. Kwok (7380419), John Sidney (19127), Julian Schulze zur Wiesch (8343450)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Infectious Diseases, Virology, 135 overlapping 15, ex vivo <, 160 ), mem_p36, hla binding assays, cell epitopes using, div >< p, mer peptides covering, broadly directed sars, cell response directed, patients elicited one, identified 10 n, 19 , e ), membrane, cell response, vitro <, 190 ), hla restriction, cell responses, response frequency

Relation: https://figshare.com/articles/dataset/Overview_of_the_most_frequently_detected_peptides_of_the_SARS-CoV-2_nucleo_membrane_and_envelope-protein_by_CD4_T_cells_in_previously_published_studies_/16629518

الاتاحة: https://doi.org/10.1371/journal.ppat.1009842.t005