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المؤلفون: Javier Rueda-Carrasco, Paula Garcia-Esparcia, Inmaculada Crespo, José A. Esteban, Juan Fortea, Pilar Esteve, José M. Valpuesta, Alberto Lleó, Guadalupe Pereyra, Estrella Gómez-Tortosa, María Jesús Martín-Bermejo, Isidro Ferrer, Mercedes Domínguez, Jonathan E. Draffin, Paola Bovolenta, Inmaculada Moreno, Daniel Alcolea, Alberto Rábano, Ester Aso, África Sandonís, Michael T. Heneka, María Inés Mateo
المساهمون: Ministerio de Economía y Competitividad (España), Fundación Tatiana Pérez de Guzmán el Bueno, Fundación Ramón Areces
المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature reviews / Neuroscience 22(8), 1258-1268 (2019). doi:10.1038/s41593-019-0432-1
NATURE NEUROSCIENCE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pauمصطلحات موضوعية: 0301 basic medicine, metabolism [Intercellular Signaling Peptides and Proteins], genetics [Plaque, Amyloid], ADAM10, Long-Term Potentiation, genetics [Amyloid Precursor Protein Secretases], Plaque, Amyloid, genetics [Alzheimer Disease], APP protein, human, Pathogenesis, antagonists & inhibitors [Membrane Proteins], genetics [ADAM10 Protein], pathology [Alzheimer Disease], Mice, Amyloid beta-Protein Precursor, ADAM10 Protein, 0302 clinical medicine, Adam10 protein, mouse, drug therapy [Plaque, Amyloid], therapeutic use [Antibodies, Blocking], Metalloproteinase, General Neuroscience, genetics [Intercellular Signaling Peptides and Proteins], Long-term potentiation, Cell biology, genetics [Membrane Proteins], genetics [Amyloid beta-Protein Precursor], Intercellular Signaling Peptides and Proteins, metabolism [Alzheimer Disease], Amyloid, Transgene, Down-Regulation, Mice, Transgenic, Biology, biosynthesis [Membrane Proteins], 03 medical and health sciences, genetics [Brain Chemistry], Downregulation and upregulation, Secreted frizzled-related protein 1, Alzheimer Disease, ddc:570, mental disorders, Neurites, Animals, Humans, Sfrp1 protein, mouse, pathology [Plaque, Amyloid], Antibodies, Blocking, biosynthesis [ADAM10 Protein], Brain Chemistry, Membrane Proteins, 030104 developmental biology, biosynthesis [Amyloid Precursor Protein Secretases], Amyloid Precursor Protein Secretases, Neuroscience, 030217 neurology & neurosurgery, metabolism [Membrane Proteins], pathology [Neurites]
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المؤلفون: Frits Kamp, Michael Willem, Ann-Katrin Ludwig, Christian Haass, Sven Lammich, Judith Wagner, Brigitte Nuscher, Sonja Zilow
المصدر: The journal of biological chemistry 286(52), 45063-45072 (2011). doi:10.1074/jbc.M111.296921
مصطلحات موضوعية: Five prime untranslated region, ADAM10, ADAM10 protein, human, physiology [Protein Biosynthesis], genetics [Amyloid Precursor Protein Secretases], physiology [5' Untranslated Regions], genetics [ADAM Proteins], Biology, Biochemistry, Nucleic acid secondary structure, biosynthesis [Membrane Proteins], ADAM10 Protein, Protein biosynthesis, Amyloid precursor protein, Humans, Gene Regulation, Nucleic acid structure, Molecular Biology, Protein secondary structure, biosynthesis [ADAM Proteins], Membrane Proteins, Cell Biology, genetics [Membrane Proteins], ADAM Proteins, HEK293 Cells, biosynthesis [Amyloid Precursor Protein Secretases], Protein Biosynthesis, ddc:540, Mutation, biology.protein, Nucleic Acid Conformation, Amyloid Precursor Protein Secretases, Sequence motif, 5' Untranslated Regions
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المؤلفون: Christian Haass, Sonja Zilow, Claudia Prinzen, Ann-Katrin Ludwig, Dominik Buell, Stefan F. Lichtenthaler, Brigitte Nuscher, Sven Lammich, Falk Fahrenholz
المصدر: The journal of biological chemistry 285(21), 15753-15760 (2010). doi:10.1074/jbc.M110.110742
مصطلحات موضوعية: Five prime untranslated region, enzymology [Brain], ADAM10, ADAM10 protein, human, BACE1-AS, genetics [Amyloid Precursor Protein Secretases], genetics [Alzheimer Disease], genetics [ADAM Proteins], Biochemistry, Gene Expression Regulation, Enzymologic, biosynthesis [Membrane Proteins], ADAM10 Protein, Alzheimer Disease, Chlorocebus aethiops, Amyloid precursor protein, Protein biosynthesis, biosynthesis [Amyloid beta-Peptides], genetics [Amyloid beta-Peptides], Animals, Humans, Gene Regulation, Molecular Biology, Sequence Deletion, biosynthesis [ADAM Proteins], Amyloid beta-Peptides, biology, Base Sequence, P3 peptide, enzymology [Alzheimer Disease], Brain, Membrane Proteins, Cell Biology, Molecular biology, Biochemistry of Alzheimer's disease, genetics [Membrane Proteins], ADAM Proteins, biosynthesis [Amyloid Precursor Protein Secretases], Protein Biosynthesis, ddc:540, COS Cells, biology.protein, Amyloid Precursor Protein Secretases, 5' Untranslated Regions, Amyloid precursor protein secretase