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المؤلفون: Frank Szulzewsky, Susanne A. Wolf, Christian J. Hoffmann, Gisela Lättig-Tünnemann, Ulrike Harms, André Rex, Ulrike Grittner, Helmut Kettenmann, Michael Sendtner, Christoph Harms, Matthias Endres, Ulrich Dirnagl
المصدر: Circulation 131(20), 1772-1782 (2015). doi:10.1161/CIRCULATIONAHA.114.013003
مصطلحات موضوعية: Angiogenesis, genetics [ADAM Proteins], deficiency [STAT3 Transcription Factor], Brain ischemia, Mice, pathology [Brain], physiology [Neuronal Plasticity], Phosphorylation, STAT3, Oligonucleotide Array Sequence Analysis, biosynthesis [ADAM Proteins], Mice, Knockout, education.field_of_study, Extracellular Matrix Proteins, Neuronal Plasticity, biology, Stat3 protein, mouse, metabolism [Extracellular Matrix Proteins], Brain, pathology [Microglia], Infarction, Middle Cerebral Artery, pathology [Infarction, Middle Cerebral Artery], Cellular Microenvironment, physiopathology [Infarction, Middle Cerebral Artery], physiology [Neovascularization, Physiologic], Cerebrovascular Circulation, Knockout mouse, metabolism [Endothelium, Vascular], Microglia, medicine.symptom, Function and Dysfunction of the Nervous System, Cardiology and Cardiovascular Medicine, Signal Transduction, STAT3 Transcription Factor, Population, Ischemia, Neovascularization, Physiologic, ADAMTS9 Protein, Lesion, Physiology (medical), physiology [Signal Transduction], medicine, Animals, ddc:610, education, physiology [Axons], Adamts9 protein, mouse, business.industry, Gene Expression Profiling, Convalescence, Recovery of Function, genetics [STAT3 Transcription Factor], medicine.disease, Axons, ADAM Proteins, Immunology, biology.protein, STAT protein, Cancer research, physiology [STAT3 Transcription Factor], Endothelium, Vascular, business, Protein Processing, Post-Translational
وصف الملف: application/pdf
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المؤلفون: Frits Kamp, Michael Willem, Ann-Katrin Ludwig, Christian Haass, Sven Lammich, Judith Wagner, Brigitte Nuscher, Sonja Zilow
المصدر: The journal of biological chemistry 286(52), 45063-45072 (2011). doi:10.1074/jbc.M111.296921
مصطلحات موضوعية: Five prime untranslated region, ADAM10, ADAM10 protein, human, physiology [Protein Biosynthesis], genetics [Amyloid Precursor Protein Secretases], physiology [5' Untranslated Regions], genetics [ADAM Proteins], Biology, Biochemistry, Nucleic acid secondary structure, biosynthesis [Membrane Proteins], ADAM10 Protein, Protein biosynthesis, Amyloid precursor protein, Humans, Gene Regulation, Nucleic acid structure, Molecular Biology, Protein secondary structure, biosynthesis [ADAM Proteins], Membrane Proteins, Cell Biology, genetics [Membrane Proteins], ADAM Proteins, HEK293 Cells, biosynthesis [Amyloid Precursor Protein Secretases], Protein Biosynthesis, ddc:540, Mutation, biology.protein, Nucleic Acid Conformation, Amyloid Precursor Protein Secretases, Sequence motif, 5' Untranslated Regions
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المؤلفون: Christian Haass, Sonja Zilow, Claudia Prinzen, Ann-Katrin Ludwig, Dominik Buell, Stefan F. Lichtenthaler, Brigitte Nuscher, Sven Lammich, Falk Fahrenholz
المصدر: The journal of biological chemistry 285(21), 15753-15760 (2010). doi:10.1074/jbc.M110.110742
مصطلحات موضوعية: Five prime untranslated region, enzymology [Brain], ADAM10, ADAM10 protein, human, BACE1-AS, genetics [Amyloid Precursor Protein Secretases], genetics [Alzheimer Disease], genetics [ADAM Proteins], Biochemistry, Gene Expression Regulation, Enzymologic, biosynthesis [Membrane Proteins], ADAM10 Protein, Alzheimer Disease, Chlorocebus aethiops, Amyloid precursor protein, Protein biosynthesis, biosynthesis [Amyloid beta-Peptides], genetics [Amyloid beta-Peptides], Animals, Humans, Gene Regulation, Molecular Biology, Sequence Deletion, biosynthesis [ADAM Proteins], Amyloid beta-Peptides, biology, Base Sequence, P3 peptide, enzymology [Alzheimer Disease], Brain, Membrane Proteins, Cell Biology, Molecular biology, Biochemistry of Alzheimer's disease, genetics [Membrane Proteins], ADAM Proteins, biosynthesis [Amyloid Precursor Protein Secretases], Protein Biosynthesis, ddc:540, COS Cells, biology.protein, Amyloid Precursor Protein Secretases, 5' Untranslated Regions, Amyloid precursor protein secretase