نتائج البحث - "biosynthesis"

1

Academic Journal

GlycoMaple: recent updates and applications in visualization and analysis of glycosylation pathways: GlycoMaple: recent updates and applications in visualization and analysis of glycosylation pathways: Kong and Fujita.

المؤلفون: Kong, Wei-Ze¹ (AUTHOR), Fujita, Morihisa¹ (AUTHOR) fujita.morihisa.h3@f.gifu-u.ac.jp

المصدر: Analytical & Bioanalytical Chemistry. Feb2025, Vol. 417 Issue 5, p885-894. 10p.

مصطلحات موضوعية: *BIOSYNTHESIS, *BIOMACROMOLECULES, *GLYCOSIDASES, *GLYCAN structure, *GOLGI apparatus, *POST-translational modification

2

Academic Journal

Computational assessment of the binding modes of the first VHL-recruiting PROTACs designed for oncogenic KRas^G12C.

المؤلفون: Franca, Tanos C. C.¹ (AUTHOR) steven.laplante@inrs.ca, Delaire, Eleonore K. M.² (AUTHOR), Drummond, Michael³ (AUTHOR), Ebert, Maximilian C. C. J. C.⁴ (AUTHOR), Ajamian, Al⁵ (AUTHOR), LaPlante, Steven R.⁶ (AUTHOR)

المصدر: New Journal of Chemistry. 2/7/2025, Vol. 49 Issue 5, p1596-1606. 11p.

مصطلحات موضوعية: *BIOSYNTHESIS, *WARHEADS, *MOLECULES

3

Academic Journal

Synthesis and Biological Activity of Penaresidins A and B, Penazetidine A, and Related Analogues.

المؤلفون: Burns, Sean M.¹ (AUTHOR), McClure, Timothy J.¹ (AUTHOR), Parikh, Seren G.¹ (AUTHOR), Schindler, Corinna S.¹ (AUTHOR) corinnas@umich.edu

المصدر: Synthesis. Feb2025, Vol. 57 Issue 3, p571-596. 26p.

مصطلحات موضوعية: *BIOSYNTHESIS, *AZETIDINE, *SPONGES (Invertebrates)

4

Academic Journal

Synthesis and biological evaluation of oleanolic acid derivatives as potential c-kit inhibitors.

المؤلفون: Kuai, Zhen-Yu¹ (AUTHOR) zhenyukuai999@163.com, Zhu, Zheng-Fei¹ (AUTHOR), Zeng, Xuan¹ (AUTHOR), Meng, Yan-Qiu² (AUTHOR)

المصدر: Journal of Asian Natural Products Research. Jan2025, p1-13. 13p. 4 Illustrations.

مصطلحات موضوعية: *C-kit protein, *BIOSYNTHESIS, *MOLECULAR docking, *ANTINEOPLASTIC agents, *CHEMICAL synthesis

5

Academic Journal

Synthesis and Anticancer Evaluation of O -Alkylated (E) -Chalcone Derivatives: A Focus on Estrogen Receptor Inhibition.

المؤلفون: Al-Ghamdi, Alwah R.¹ (AUTHOR) 439204477@student.ksu.edu.sa, Ahmed, Wahid U.² (AUTHOR) ahmeduddin.live@gmail.com, Al-Wabli, Reem I.¹ (AUTHOR) ralwabli@ksu.edu.sa, Al-Mutairi, Maha S.¹ (AUTHOR) malmutbiri@ksu.edu.sa, Rahman, A. F. M. Motiur¹ (AUTHOR) malmutbiri@ksu.edu.sa

المصدر: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p833. 24p.

مصطلحات موضوعية: *BIOSYNTHESIS, *PROTEIN kinases, *ESTROGEN receptors, *ALDOL condensation, *CYCLIN-dependent kinases, *CHALCONE

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6

Academic Journal

Synthesis and biological evaluation of aryl derivatives of indole-1,3,4-thiadiazole as anticancer agents.

المؤلفون: Kalagara, Sudhakar¹ (AUTHOR) baddamsudhakar@gmail.com, Baddam, Sudhakar Reddy² (AUTHOR), Ganta, Srinivas³ (AUTHOR), Vudari, Balaraju⁴ (AUTHOR), Enaganti, Sreenivas⁵ (AUTHOR), Damarancha, Anil⁶ (AUTHOR), Eppakayala, Laxminarayana⁴ (AUTHOR)

المصدر: Synthetic Communications. 2025, Vol. 55 Issue 2, p138-145. 8p.

مصطلحات موضوعية: *COLON cancer, *BIOSYNTHESIS, *CHEMICAL synthesis, *LUNG cancer, *OVARIAN cancer

7

Academic Journal

Quinizarin Gold(I) N‐Heterocyclic Carbene Complexes with Synergistic Activity Against Anthracycline‐Resistant Leukaemia Cells: Synthesis and Biological Activity Studies.

المؤلفون: Steinbrueck, Axel¹ (AUTHOR), Reback, Matthew L.¹ (AUTHOR), Rumancev, Christoph² (AUTHOR), Siegmund, Daniel^1,3 (AUTHOR), Garrevoet, Jan⁴ (AUTHOR), Falkenberg, Gerald⁴ (AUTHOR), Rosenhahn, Axel² (AUTHOR), Prokop, Aram^5,6 (AUTHOR), Metzler‐Nolte, Nils¹ (AUTHOR) Nils.Metzler-Nolte@rub.de

المصدر: Chemistry - A European Journal. Jan2025, p1. 9p. 11 Illustrations.

مصطلحات موضوعية: *DRUG resistance in cancer cells, *BIOSYNTHESIS, *INORGANIC chemistry, *X-ray fluorescence, *PHARMACEUTICAL chemistry

8

Academic Journal

[ 99m Tc]Technetium and Rhenium Dithiocarbazate Complexes: Chemical Synthesis and Biological Assessment.

المؤلفون: de Araujo Fernandes, André Gustavo^1,2 (AUTHOR) agafernandes@uesc.br, Lafratta, Alyne Eloise³ (AUTHOR) alyne@alumni.usp.br, Luz, Carolina Portela³ (AUTHOR) carol.p.luz@gmail.com, Levy, Debora⁴ (AUTHOR) d.levy@fm.usp.br, de Paula Faria, Daniele³ (AUTHOR) danielefaria1@gmail.com, Buchpiguel, Carlos Alberto³ (AUTHOR) buch@usp.br, Abram, Ulrich⁵ (AUTHOR) ulrich.abram@fu-berlin.de, Deflon, Victor Marcelo¹ (AUTHOR) deflon@iqsc.usp.br, Navarro Marques, Fabio Luiz³ (AUTHOR) deflon@iqsc.usp.br

المصدر: Pharmaceutics. Jan2025, Vol. 17 Issue 1, p100. 16p.

مصطلحات موضوعية: *BIOSYNTHESIS, *COMPUTED tomography, *CHEMICAL synthesis, *AMINO acids, *TECHNETIUM

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9

Academic Journal

(E)-1-(3-(3-Hydroxy-4-Methoxyphenyl)-1-(3,4,5-Trimethoxyphenyl)allyl)-1 H -1,2,4-Triazole and Related Compounds: Their Synthesis and Biological Evaluation as Novel Antimitotic Agents Targeting Breast Cancer.

المؤلفون: Ana, Gloria¹ (AUTHOR), Malebari, Azizah M.² (AUTHOR), Noorani, Sara¹ (AUTHOR), Fayne, Darren^3,4 (AUTHOR), O'Boyle, Niamh M.¹ (AUTHOR), Zisterer, Daniela M.⁵ (AUTHOR), Pimentel, Elisangela Flavia⁶ (AUTHOR), Endringer, Denise Coutinho⁶ (AUTHOR), Meegan, Mary J.¹ (AUTHOR) mmeegan@tcd.ie

المصدر: Pharmaceuticals (14248247). Jan2025, Vol. 18 Issue 1, p118. 54p.

مصطلحات موضوعية: *TRIPLE-negative breast cancer, *BIOSYNTHESIS, *NON-small-cell lung carcinoma, *MOLECULAR docking, *CELL cycle

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10

Academic Journal

Siccanin-related drimane meroterpenoids: biological activities and synthesis.

المؤلفون: Sun, Shengxin¹ (AUTHOR), Wang, Xia¹ (AUTHOR), Hu, Nvdan¹ (AUTHOR), Fu, Shiqi¹ (AUTHOR), Li, Shengkun¹ (AUTHOR) SKL505@outlook.com

المصدر: Natural Product Reports. Jan2025, Vol. 42 Issue 1, p113-150. 38p.

مصطلحات موضوعية: *BIOSYNTHESIS, *HYDROQUINONE, *TERPENES, *NATURAL products, *PHENOLS

11

Academic Journal

1,10-Phenanthroline and 4,5-Diazafluorene Ketones and Their Silver(I) and Platinum(II) Complexes: Syntheses and Biological Evaluation as Antiproliferative Agents.

المؤلفون: Sandin-Mazzondo, Leonardo¹ (AUTHOR) leonardoraphael.sandin@uva.es, Martínez-Ilarduya, Jesús M.¹ (AUTHOR) jesusmaria.martinez-ilarduya@uva.es, Miguel, Jesús A.¹ (AUTHOR) jamiguel@uva.es, Bartolomé, Camino¹ (AUTHOR) camino.bartolome@uva.es, Alonso, Concepción² (AUTHOR) camino.bartolome@uva.es

المصدر: Inorganics. Jan2025, Vol. 13 Issue 1, p6. 22p.

مصطلحات موضوعية: *BIOSYNTHESIS, *CYTOTOXINS, *LIGANDS (Biochemistry), *KETONES, *CISPLATIN

12

Academic Journal

Genetic Background and Phenotypic Aspects of Light-Induced Carotenoid Biosynthesis in Isosphaeraceae Planctomycetes.

المؤلفون: Ivanova, Anastasia A.¹ (AUTHOR) vinnigo@gmail.com, Oshkin, Igor Y.¹ (AUTHOR) dedysh@mail.ru, Ashikhmin, Aleksandr A.² (AUTHOR), Danilova, Olga V.¹ (AUTHOR), Dedysh, Svetlana N.¹ (AUTHOR)

المصدر: Microbiology Research. Jan2025, Vol. 16 Issue 1, p5. 11p.

مصطلحات موضوعية: *BIOSYNTHESIS, *GENE clusters, *GENOMES, *PHENOTYPES, *SQUALENE, *CAROTENOIDS

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13

Academic Journal

New transaminase from Odontosyllis undecimdonta the first potential enzyme of the luciferin biosynthesis pathway.

المؤلفون: Dmitrieva, Daria A.¹ (AUTHOR), Belozerova, Olga A.² (AUTHOR), Mishin, Alexey V.¹ (AUTHOR), Yampolsky, Ilia V.^2,3 (AUTHOR), Kotlobay, Alexey A.^1,2 (AUTHOR) alexey_kotlobay@ibch.ru

المصدر: Biochimie. Jan2025, Vol. 228, p82-88. 7p.

مصطلحات موضوعية: *BIOSYNTHESIS, *BIOLUMINESCENCE, *POLYCHAETA, *ENZYMES

14

Academic Journal

Evidence for corrin biosynthesis in the last universal common ancestor.

المؤلفون: Modjewski, Luca D.¹ (AUTHOR), Karavaeva, Val^2,3 (AUTHOR), Mrnjavac, Natalia¹ (AUTHOR), Knopp, Michael¹ (AUTHOR), Martin, William F.¹ (AUTHOR), Sousa, Filipa L.² (AUTHOR) filipa.sousa@univie.ac.at

المصدر: FEBS Journal. Dec2024, p1. 24p. 8 Illustrations.

مصطلحات موضوعية: *LIGAND biosynthesis, *MOLECULAR evolution, *OXIDATION-reduction reaction, *VITAMIN B12, *CARBON isotopes, *COFACTORS (Biochemistry)

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15

Academic Journal

A comprehensive review on the properties, production, and applications of functional glucobioses.

المؤلفون: Zhang, Shuqi¹ (AUTHOR), Ni, Dawei¹ (AUTHOR) daweini@jiangnan.edu.cn, Zhu, Yingying¹ (AUTHOR), Xu, Wei¹ (AUTHOR), Zhang, Wenli¹ (AUTHOR), Mu, Wanmeng^1,2 (AUTHOR)

المصدر: Critical Reviews in Food Science & Nutrition. 2024, Vol. 64 Issue 33, p13149-13162. 14p.

مصطلحات موضوعية: *MOLECULAR structure, *BIOSYNTHESIS, *DISACCHARIDES, *NATURAL resources, *MANUFACTURING processes

16

Academic Journal

Molecular modeling, synthesis and biological evaluation of caffeic acid based Dihydrofolate reductase inhibitors.

المؤلفون: Sehrawat, Renu¹ (AUTHOR), Pasrija, Ritu² (AUTHOR), Rathee, Priyanka³ (AUTHOR), Kumari, Deepika² (AUTHOR), Khatkar, Anurag⁴ (AUTHOR) anuragpharmacy@gmail.com

المصدر: BMC Chemistry. 12/18/2024, Vol. 18 Issue 1, p1-22. 22p.

مصطلحات موضوعية: *BIOSYNTHESIS, *LIFE sciences, *BINDING sites, *TETRAHYDROFOLATE dehydrogenase, *REDUCTASE inhibitors

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17

Academic Journal

Synthesis and Biological Evaluation of Deoxycyclophellitols as Human Retaining β‐Glucosidase Inhibitors.

المؤلفون: Radchenko, Yevhenii¹ (AUTHOR), Su, Qin¹ (AUTHOR), Schröder, Sybrin S.¹ (AUTHOR), van Gijlswijk, Luke¹ (AUTHOR), Artola, Marta¹ (AUTHOR), Aerts, Johannes M. F. G.¹ (AUTHOR), Codée, Jeroen D. C.¹ (AUTHOR), Overkleeft, Herman S.¹ (AUTHOR) h.s.overkleeft@chem.leidenuniv.nl

المصدر: Chemistry - A European Journal. 12/13/2024, Vol. 30 Issue 70, p1-6. 6p.

مصطلحات موضوعية: *GLUCOSIDASE inhibitors, *BIOSYNTHESIS, *AZIRIDINES, *EPOXY compounds, *DEOXYGENATION

18

Academic Journal

Synthesis and biological evaluation of β-lactams as potent antidiabetic agents.

المؤلفون: Shaheen, Salma¹ (AUTHOR), Arshad, Jahan Zaib² (AUTHOR) jahanzaib.arshad@gcwus.edu.pk, Haider, Mansoor³ (AUTHOR), Ashraf, Adnan⁴ (AUTHOR), Ahmad, Muhammad Mahboob⁵ (AUTHOR), Ashfaq, Muhammad¹ (AUTHOR), Ismail, Mostafa A.⁶ (AUTHOR), Najam, Tayyaba⁷ (AUTHOR) tayyabanajam@outlook.com, Shah, Syed Shoaib Ahmad⁸ (AUTHOR) shoaib03ahmad@outlook.com

المصدر: New Journal of Chemistry. 12/14/2024, Vol. 48 Issue 46, p19427-19440. 14p.

مصطلحات موضوعية: *TYPE 2 diabetes, *BIOSYNTHESIS, *IMINE derivatives, *BLOOD sugar, *DRUG bioavailability, *LACTAMS, *GLUCOSIDASES, *ALPHA-glucosidases

19

Academic Journal

Synthesis and Biological Evaluation of p‐Aminophenol Derivatives Applying In Vivo, Ex Vivo, and In Silico Approach.

المؤلفون: Das, Ananta Kumar¹ (AUTHOR) ananta.pharmacy@gonouniversity.edu.bd, Islam, A. F. M. Mahmudul¹ (AUTHOR), Rouf, Md. Abdur¹ (AUTHOR), Paul, Prosenjit¹ (AUTHOR), Hassan, Md. Jahid¹ (AUTHOR), Roy, Saurabh¹ (AUTHOR), Esha, Esrat Jahan¹ (AUTHOR), Hossain, Md. Selim² (AUTHOR), Hossain, Md. Monir³ (AUTHOR), Hossain, Md. Emdad⁴ (AUTHOR), Saha, Koushik^4,5 (AUTHOR)

المصدر: ChemistrySelect. 12/10/2024, Vol. 9 Issue 46, p1-15. 15p.

مصطلحات موضوعية: *BIOSYNTHESIS, *MOLECULAR docking, *CHEMICAL yield, *CYTOTOXINS, *ALBUMINS

20

Academic Journal

Synthesis and biological assessment of chalcone and pyrazoline derivatives as novel inhibitor for ELF3-MED23 interaction.

المؤلفون: Soo-Yeon Hwang¹, Kyung-Hwa Jeon¹, Hwa-Jong Lee¹, Inhye Moon¹, Sehyun Jung¹, Seul-Ah Kim¹, Hyunji Jo¹, Seojeong Park¹, Misun Ahn¹, Soo-Yeon Kwak², Younghwa Na² yna7315@cha.ac.kr, Youngjoo Kwon¹ ykwon@ewha.ac.kr

المصدر: eLife. 12/5/2024, p1-26. 26p.

مصطلحات موضوعية: *BIOSYNTHESIS, *HER2 protein, *STOMACH cancer, *ANTINEOPLASTIC agents, *REPORTER genes, *CHALCONE

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