نتائج البحث - "binding protein 43"

المساهمون: Unité de recherche en NeuroImagerie Applicative Clinique et Translationnelle (UNIACT), Service NEUROSPIN (NEUROSPIN), Université Paris-Saclay-Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), LaBoratoire d'Imagerie biOmédicale MultimodAle Paris-Saclay (BIOMAPS), Service Hospitalier Frédéric Joliot (SHFJ), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Neurologie de la mémoire et du langage CHU Ste Anne, Université Paris Descartes - Paris 5 (UPD5), Université Paris Cité (UPCité), GHU Paris Psychiatrie et Neurosciences, Centre d'évaluation troubles psychiques et vieillissement, GHU Paris Psychiatrie & Neurosciences, Hôpital Sainte Anne, Paris, French Ministry of Health, Grant/Award Numbes: PHRC-2013-0919, French Ministry of Health, Grant/Award Number: PHRC-0054-N2010

المصدر: ISSN: 1552-5260 ; EISSN: 1552-5279 ; Alzheimer's & Dementia : the Journal of the Alzheimer's Association.

مصطلحات موضوعية: Alzheimer's disease, Diffusion magnetic resonance imaging, Fixel-based analysis, Limbic-predominant age-related TAR DNA-binding protein 43 encephalopathy, White matter, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, [SCCO.NEUR]Cognitive science/Neuroscience, [SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology

Relation: info:eu-repo/semantics/altIdentifier/pmid/39193664; PUBMED: 39193664

الاتاحة: https://cea.hal.science/cea-04711376
https://cea.hal.science/cea-04711376v1/document
https://cea.hal.science/cea-04711376v1/file/Lebrun%20et%20al.%20-%202024%20-%20How%20fiber%20bundle%20alterations%20differ%20in%20presumed%20LA.pdf
https://doi.org/10.1002/alz.14156

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6

Academic Journal

Detection of TDP-43 seeding activity in the olfactory mucosa from patients with frontotemporal dementia

المساهمون: Fontana, Elena, Bongianni, Matilde, Benussi, Alberto, Bronzato, Erika, Scialo, Carlo, Sacchetto, Luca, Cagnin, Annachiara, Castriciano, Santina, Buratti, Emanuele, Gardoni, Fabrizio, Italia, Maria, Schreiber, Alberto, Ferracin, Chiara, Fiorini, Michele, Newell, Kathy L, Cracco, Laura, Garringer, Holly J, Cecchini, Maria Paola, Polymenidou, Magdalini, Padovani, Alessandro, Monaco, Salvatore, Legname, Giuseppe, Ghetti, Bernardino, Borroni, Barbara, Zanusso, Gianluigi

مصطلحات موضوعية: TAR DNA-binding protein 43, frontotemporal dementia, frontotemporal lobar degeneration, olfactory mucosa, seeding, seeding amplification assays

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/37908186; info:eu-repo/semantics/altIdentifier/wos/WOS:001093924400001; volume:20; issue:2; firstpage:1156; lastpage:1165; numberofpages:10; journal:ALZHEIMER'S & DEMENTIA; https://hdl.handle.net/11562/1112366; https://doi.org/10.1002/alz.13541

الاتاحة: https://hdl.handle.net/11562/1112366
https://doi.org/10.1002/alz.13541

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7

Academic Journal

Frontotemporal dementia: from genetics to therapeutic approaches

المؤلفون: Buccellato, Francesca R., D'Anca, Marianna, Tartaglia, Gianluca Martino, Del Fabbro, Massimo, Galimberti, Daniela

المساهمون: F.R. Buccellato, M. D'Anca, G.M. Tartaglia, M. Del Fabbro, D. Galimberti

مصطلحات موضوعية: Frontotemporal dementia (FTD), Progranulin (GRN), TAR DNA-binding protein 43 (TDP-43), chromosome 9 open reading frame 72 (C9orf72), frontotemporal lobar degeneration (FTLD), microtubule associated protein tau (MAPT), Settore BIO/13 - Biologia Applicata

Relation: info:eu-repo/semantics/altIdentifier/pmid/38687620; info:eu-repo/semantics/altIdentifier/wos/WOS:001217067300001; volume:33; issue:6; firstpage:561; lastpage:573; numberofpages:13; journal:EXPERT OPINION ON INVESTIGATIONAL DRUGS; https://hdl.handle.net/2434/1077069; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85192563467

الاتاحة: https://hdl.handle.net/2434/1077069
https://doi.org/10.1080/13543784.2024.2349286

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8

Academic Journal

Molecular fragment characteristics and distribution of tangle associated TDP-43 (TATs) and other TDP-43 lesions in Alzheimer’s disease

المؤلفون: Keith Anthony Josephs, Shunsuke Koga, Nirubol Tosakulwong, Stephen D. Weigand, Nha Trang Thu Pham, Matt Baker, Jennifer L. Whitwell, Rosa Rademakers, Leonard Petrucelli, Dennis W. Dickson

المصدر: Free Neuropathology, Vol 4 (2023)

مصطلحات موضوعية: TAR DNA binding protein 43, TMEM106b, Cluster analysis, TAT, Hippocampal sclerosis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/5192; https://doaj.org/toc/2699-4445

URL الوصول: https://doaj.org/article/2d46bc8252ce424389373b1fbe98dfdc

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9

Academic Journal

A robust TDP-43 knock-in mouse model of ALS

المؤلفون: Huang, Shih-Ling, Wu, Lien-Szu, Lee, Min, Chang, Chin-Wen, Cheng, Wei-Cheng, Fang, Yu-Sheng, Chen, Yun-Ru, Cheng, Pei-Lin, Shen, Che-Kun James

المصدر: Acta Neuropathologica Communications. 8(1)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Neurosciences, Genetics, Rare Diseases, Stem Cell Research, Brain Disorders, Neurodegenerative, ALS, 2.1 Biological and endogenous factors, Aetiology, Neurological, Amyotrophic Lateral Sclerosis, Animals, Autophagy, Cell Line, DNA-Binding Proteins, Disease Models, Animal, Embryonic Stem Cells, Female, Gene Knock-In Techniques, Male, Mice, Transgenic, Motor Neurons, Muscle, Skeletal, Protein Aggregation, Pathological, Spinal Cord, ALS-TDP pathogenesis, Amyotrophic lateral sclerosis, Autonomous spinal cord motor neuron degeneration, Homologous knock-in mouse models with ALS-associated TDP-43 mutations, Mis-splicing of Bcl-2 pre-mRNA, TAR DNA-binding protein 43, Biochemistry and Cell Biology, Clinical Sciences, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2732x3nv
https://escholarship.org/content/qt2732x3nv/qt2732x3nv.pdf

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10

Academic Journal

A candidate protective factor in amyotrophic lateral sclerosis: heterogenous nuclear ribonucleoprotein G

المؤلفون: Fang Yang, Wen-Zhi Chen, Shi-Shi Jiang, Xiao-Hua Wang, Ren-Shi Xu

المصدر: Neural Regeneration Research, Vol 18, Iss 7, Pp 1527-1534 (2023)

مصطلحات موضوعية: amyotrophic lateral sclerosis, bax, heterogenous nuclear ribonucleoprotein g, heterogenous nuclear ribonucleoprotein g-sirna, neuron death, superoxide dismutase 1, tar dna binding protein 43, tg(sod1*g93a)1gur mice, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=7;spage=1527;epage=1534;aulast=Yang; https://doaj.org/toc/1673-5374

URL الوصول: https://doaj.org/article/80bdc7bdfdfb4913951b87cbc88048ce

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11

Academic Journal

5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis

المؤلفون: Shi-Shi Jiang, Meng-Ni Gong, Wei Rao, Wen Chai, Wen-Zhi Chen, Xiong Zhang, Hong-Bing Nie, Ren-Shi Xu

المصدر: Neural Regeneration Research, Vol 18, Iss 9, Pp 2047-2055 (2023)

مصطلحات موضوعية: 5-hydroxytryptamine, amyotrophic lateral sclerosis, astrocytes, granisetron, microglia, neuron, piboserod, ritanserin, sod1-g93a, tar dna-binding protein 43, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=9;spage=2047;epage=2055;aulast=Jiang; https://doaj.org/toc/1673-5374

URL الوصول: https://doaj.org/article/67f6608c160642fe87df66f414804e1f

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12

Academic Journal

Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration

المؤلفون: Benjamin G. Trist, Jennifer A. Fifita, Alison Hogan, Natalie Grima, Bradley Smith, Claire Troakes, Caroline Vance, Christopher Shaw, Safa Al-Sarraj, Ian P. Blair, Kay L. Double

المصدر: Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)

مصطلحات موضوعية: Superoxide dismutase-1, TAR DNA-binding protein 43, p62/SQSTM1, Proteinopathy, Amyotrophic lateral sclerosis, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/6009cd789000488891a5da5a25f5909a

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13

Academic Journal

Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology

المؤلفون: Nana, Alissa L, Sidhu, Manu, Gaus, Stephanie E, Hwang, Ji-Hye L, Li, Libo, Park, Youngsoon, Kim, Eun-Joo, Pasquini, Lorenzo, Allen, Isabel E, Rankin, Katherine P, Toller, Gianina, Kramer, Joel H, Geschwind, Daniel H, Coppola, Giovanni, Huang, Eric J, Grinberg, Lea T, Miller, Bruce L, Seeley, William W

المصدر: Acta Neuropathologica. 137(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Frontotemporal Dementia (FTD), Dementia, Orphan Drug, Aging, Brain Disorders, Neurodegenerative, Acquired Cognitive Impairment, ALS, Alzheimer's Disease Related Dementias (ADRD), Rare Diseases, 2.1 Biological and endogenous factors, Neurological, Adult, Aged, Amyotrophic Lateral Sclerosis, C9orf72 Protein, DNA Repeat Expansion, DNA-Binding Proteins, Female, Frontotemporal Dementia, Humans, Inclusion Bodies, Male, Middle Aged, Motor Neuron Disease, Neurons, Pick Disease of the Brain, Frontotemporal dementia, Amyotrophic lateral sclerosis, TAR DNA-binding protein 43, C9orf72, Von Economo neuron, Empathy, Clinical Sciences, Neurology & Neurosurgery

URL الوصول: https://escholarship.org/uc/item/6qq1g5h5

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14

Academic Journal

Raddeanin A Enhances Mitochondrial DNA‐cGAS/STING Axis‐Mediated Antitumor Immunity by Targeting Transactive Responsive DNA‐Binding Protein 43

المؤلفون: Mingxiao Yin, Jingwen Dong, Cuicui Sun, Xiaojia Liu, Zhirui Liu, Lu Liu, Zean Kuang, Na Zhang, Dian Xiao, Xinbo Zhou, Hongbin Deng

المصدر: Advanced Science, Vol 10, Iss 13, Pp n/a-n/a (2023)

مصطلحات موضوعية: dendritic cells, immune checkpoint therapies, immunogenic cell death, STING, transactive responsive DNA‐binding protein 43, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2198-3844

URL الوصول: https://doaj.org/article/d42b462d1f7648eb8c2ea06bdd7bf67c

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15

Academic Journal

Herpes Simplex Virus 1 (HSV-1) Infected Cell Protein 0 (ICP0) Targets of Ubiquitination during Productive Infection of Primary Adult Sensory Neurons ; International Journal of Molecular Science

المؤلفون: Harrell, Telvin L., Davido, David J., Bertke, Andrea S.

مصطلحات موضوعية: HSV, human herpes virus, alphaherpesvirus, ICP0, mass spectrometry, primary neurons, HMG I/Y, High Mobility Group Protein I/Y, TDP43, TAR DNA Binding Protein 43

وصف الملف: application/pdf

Relation: Harrell, T.L.; Davido, D.J.; Bertke, A.S. Herpes Simplex Virus 1 (HSV-1) Infected Cell Protein 0 (ICP0) Targets of Ubiquitination during Productive Infection of Primary Adult Sensory Neurons. Int. J. Mol. Sci. 2023, 24, 2931.; http://hdl.handle.net/10919/113783; https://doi.org/10.3390/ijms24032931

الاتاحة: http://hdl.handle.net/10919/113783
https://doi.org/10.3390/ijms24032931

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16

Academic Journal

Molecular Graph-Based Deep Learning Algorithm Facilitates an Imaging-Based Strategy for Rapid Discovery of Small Molecules Modulating Biomolecular Condensates

المؤلفون: Peng Gao, Qi Zhang, Devin Keely, Don W. Cleveland, Yihong Ye, Wei Zheng, Min Shen, Haiyang Yu

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Biotechnology, Sociology, Space Science, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, undergoes phase transition, spatial information extraction, normal splicing function, identify small molecules, abnormal subcellular loci, graph convolutional network, based methods restrict, promote biomolecular condensates, based compound screens, binding protein 43, biomolecular condensates, molecular graph, essential protein, compound screen, based strategy, based screen, tar dna, taken together, screening scale

Relation: https://figshare.com/articles/journal_contribution/Molecular_Graph-Based_Deep_Learning_Algorithm_Facilitates_an_Imaging-Based_Strategy_for_Rapid_Discovery_of_Small_Molecules_Modulating_Biomolecular_Condensates/24525400

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c00490.s001
https://figshare.com/articles/journal_contribution/Molecular_Graph-Based_Deep_Learning_Algorithm_Facilitates_an_Imaging-Based_Strategy_for_Rapid_Discovery_of_Small_Molecules_Modulating_Biomolecular_Condensates/24525400

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17

Academic Journal

Gene Therapy in Amyotrophic Lateral Sclerosis

المؤلفون: Fang, Ton, Je, Goun, Pacut, Peter, Keyhanian, Kiandokht, Gao, Jeff, Ghasemi, Mehdi

المساهمون: Neurology

المصدر: Cells ; 11 ; 13 ; United States ; Switzerland

مصطلحات موضوعية: C9orf72, Cu/Zn superoxide dismutase (SOD1), TAR DNA binding protein 43 (TARDBP), amyotrophic lateral sclerosis (ALS), fused in sarcoma (FUS), gene therapy

Relation: Cells; https://doi.org/10.3390/cells11132066; Fang T, Je G, Pacut P, Keyhanian K, Gao J, Ghasemi M. Gene Therapy in Amyotrophic Lateral Sclerosis. Cells. 2022 Jun 29;11(13):2066. doi:10.3390/cells11132066. PMID: 35805149; PMCID: PMC9265980.; http://hdl.handle.net/20.500.14038/52674

الاتاحة: https://doi.org/10.3390/cells11132066
https://hdl.handle.net/20.500.14038/52674

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