المؤلفون: Hannah A. Taylor, Katie J. Simmons, Eva M. Clavane, Christopher J. Trevelyan, Jane M. Brown, Lena Przemyłska, Nicole T. Watt, Laura C. Matthews, Paul J. Meakin

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4568

مصطلحات موضوعية: Alzheimer’s disease, beta secretase 1 (BACE1), Netrin receptor DCC, protein tyrosine phosphatase receptor type D (PTPRD), BACE1 substrates

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms23094568

الاتاحة: https://doi.org/10.3390/ijms23094568

المؤلفون: Gaborit, Bénédicte, Govers, Roland, Altié, Alexandre, Brunel, Jean Michel, Morange, Pierre, Peiretti, Franck

المساهمون: Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Membranes et cibles thérapeutiques (MCT), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Recherche Biomédicale des Armées Brétigny-sur-Orge (IRBA), Service de Santé des Armées

المصدر: ISSN: 0021-9258.

مصطلحات موضوعية: O-GlcNacylation, autophagy, beta-secretase 1 (BACE1), diabetes, insulin receptor, liver, lysosome, proteasome, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases

Relation: info:eu-repo/semantics/altIdentifier/pmid/34029592; hal-03368302; https://hal.science/hal-03368302; https://hal.science/hal-03368302/document; https://hal.science/hal-03368302/file/MS%20peiretti%20JBC%20with%20figures.pdf; https://hal.science/hal-03368302/file/PIIS0021925821006141.pdf; PUBMED: 34029592; WOS: 000678068400020

الاتاحة: https://hal.science/hal-03368302
https://hal.science/hal-03368302/document
https://hal.science/hal-03368302/file/MS%20peiretti%20JBC%20with%20figures.pdf
https://hal.science/hal-03368302/file/PIIS0021925821006141.pdf
https://doi.org/10.1016/j.jbc.2021.100818

المؤلفون: WonHee Kim, Liang Ma, Selene Lomoio, Rachel Willen, Sylvia Lombardo, Jinghui Dong, Philip G. Haydon, Giuseppina Tesco

المصدر: Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-22 (2018)

مصطلحات موضوعية: Alzheimer disease, Amyloid-beta (Aβ), Beta-secretase 1 (BACE1), Golgi-localized γ-ear-containing ARF binding protein 3 (GGA3), Amyloid precursor protein (APP), Cell adhesion molecule L1 like protein (CHL1), Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13024-018-0239-7; https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/7258624d78f2453a9df25d037112256f

المؤلفون: Tan, Jing Zhi A., Fourriere, Lou, Wang, Jingqi, Perez, Franck, Boncompain, Gaëlle, Gleeson, Paul

المساهمون: University of Melbourne, Bio21 Molecular Science & Biotechnology Institute Melbourne (School of Chemistry), Faculty of Science Melbourne, University of Melbourne-University of Melbourne, Institut Curie Paris, Biologie Cellulaire et Cancer, Institut Curie Paris -Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: EISSN: 1939-4586 ; Molecular Biology of the Cell ; https://hal.science/hal-02986333 ; Molecular Biology of the Cell, 2020, 31 (1), pp.27-44. ⟨10.1091/mbc.E19-09-0487⟩

مصطلحات موضوعية: anterograde transport, beta-secretase 1 (BACE1), small GTPase, Arf1, Arf4, AP-1, AP-4, amyloid precursor protein (APP), amyloid beta (Aβ), trans-Golgi network, membrane transport, primary neurons Abbreviations: Aβ, beta-amyloid peptide, BACE1, beta site APP-cleaving enzyme, APP, amyloid precursor protein, AD, Alzheimer's disease, TGN, RUSH, retention using selective hooks, ER, endoplasmic reticulum, GFP, green fluorescent protein, PM, plasma membrane, TfR, transferrin receptor

Relation: hal-02986333; https://hal.science/hal-02986333; https://hal.science/hal-02986333/document; https://hal.science/hal-02986333/file/Tan,%20Fourriere%20et%20al._HAL.pdf

الاتاحة: https://hal.science/hal-02986333
https://hal.science/hal-02986333/document
https://hal.science/hal-02986333/file/Tan,%20Fourriere%20et%20al._HAL.pdf
https://doi.org/10.1091/mbc.E19-09-0487

المؤلفون: Teemu Natunen, Mari Takalo, Susanna Kemppainen, Stina Leskelä, Mikael Marttinen, Kaisa M.A. Kurkinen, Juha-Pekka Pursiheimo, Timo Sarajärvi, Jayashree Viswanathan, Sami Gabbouj, Eino Solje, Eveliina Tahvanainen, Tiina Pirttimäki, Mitja Kurki, Jussi Paananen, Tuomas Rauramaa, Pasi Miettinen, Petra Mäkinen, Ville Leinonen, Hilkka Soininen, Kari Airenne, Rudolph E. Tanzi, Heikki Tanila, Annakaisa Haapasalo, Mikko Hiltunen

المصدر: Neurobiology of Disease, Vol 85, Iss , Pp 187-205 (2016)

مصطلحات موضوعية: Alzheimer's disease, Amyloid-β (Aβ), Amyloid precursor protein (APP), Beta-secretase 1 (BACE1), Tau, Lentivirus, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S096999611530084X; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/fec99dbad77e483d989eaa39ef52f9e5

المؤلفون: Nobuhisa Iwata, Naoki Yahata, Motoi Kanagawa, Tsuneyoshi Seki, Hisatomo Kowa, Kei Maruyama, Kazuhiro Kobayashi, Haruhisa Inoue, Tatsushi Toda

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Endosome, amyloid precursor protein (APP), Induced Pluripotent Stem Cells, induced pluripotent stem cell (iPS cell) (iPSC), Endocytosis, Biochemistry, galectin 3–binding protein (GAL3BP), Cell Line, glycophosphatidylinositol-specific phospholipase D1 (GPLD1), 03 medical and health sciences, Antigens, Neoplasm, Paracrine Communication, Biomarkers, Tumor, Phospholipase D, Amyloid precursor protein, medicine, Humans, Molecular Biology, Galectin, Amyloid beta-Peptides, beta-secretase 1 (BACE1), 030102 biochemistry & molecular biology, biology, Chemistry, Neurodegeneration, HEK 293 cells, neurodegeneration, Cell Differentiation, Molecular Bases of Disease, Cell Biology, medicine.disease, Cell biology, Autocrine Communication, HEK293 Cells, 030104 developmental biology, amyloid-beta (AB), biology.protein, lectin, Alzheimer disease, Alzheimer's disease, microarray, Phospholipase D1, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c744b95f5265a88c9dc21136a878091
https://doi.org/10.1074/jbc.ra119.008703

المؤلفون: Fleck, D., Voss, M., Brankatschk, B., Giudici, C., Hampel, H., Schwenk, B.M., Edbauer, D., Fukumori, A., Steiner, H., Kremmer, E., Haug-Kröeper, M., Rossner, M.J., Fluhrer, R., Willem, M., Haass, C.

المصدر: J. Biol. Chem. 291, 318-333 (2016)

مصطلحات موضوعية: Adam, Alzheimer Disease, Amyloid-beta (ab), Beta-secretase 1 (bace1), Gamma-secretase, Neurodegeneration

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/26574544; info:eu-repo/semantics/altIdentifier/wos/WOS:000367589500025; info:eu-repo/semantics/altIdentifier/isbn/0021-9258; info:eu-repo/semantics/al; https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=47314; urn:isbn:0021-9258; urn:issn:0021-9258; urn:issn:1083-351X

الاتاحة: https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=47314
https://doi.org/10.1074/jbc.M115.697995

المؤلفون: Bénédicte, Gaborit, Roland, Govers, Alexandre, Altié, Jean Michel, Brunel, Pierre, Morange, Franck, Peiretti

المساهمون: Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Membranes et cibles thérapeutiques (MCT), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Recherche Biomédicale des Armées (IRBA), Service de Santé des Armées, Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Brunel, Jean Michel

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297 (1), pp.100818. ⟨10.1016/j.jbc.2021.100818⟩
Journal of Biological Chemistry, 2021, 297 (1), pp.100818. ⟨10.1016/j.jbc.2021.100818⟩
The Journal of Biological Chemistry

مصطلحات موضوعية: O-GlcNacylation, HFD, high-fat diet, autophagy, Glycosylation, BACE1, β-secretase 1, ERLAD, ER-to-lysosome-associated degradation, liver, Models, Biological, Diabetes Mellitus, Experimental, ERAD, ER-associated degradation, ER, endoplasmic reticulum, APP, amyloid precursor protein, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, mental disorders, Animals, Aspartic Acid Endopeptidases, Humans, insulin receptor, BAF, Bafilomycin A1, TGN, trans Golgi network, Secretory Pathway, beta-secretase 1 (BACE1), Cholestanes, AD, Alzheimer disease, diabetes, Ubiquitin, Ubiquitination, PC, proprotein convertase, Hep G2 Cells, Endoplasmic Reticulum Stress, Receptor, Insulin, Disease Models, Animal, HEK293 Cells, proteasome, ESP, early secretory pathway, IR, insulin receptor, Proteolysis, Proteostasis, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, lysosome, Spermine, PTM, posttranslational modification, Amyloid Precursor Protein Secretases, HBP, hexosamine biosynthetic pathway, Protein Binding, Research Article

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d438b123de19467c77e8e9b4739301bb
https://hal.archives-ouvertes.fr/hal-03368302

المؤلفون: Gaelle Boncompain, Lou Fourriere, Paul A. Gleeson, Jing Zhi A. Tan, Franck Perez, Jingqi Wang

المساهمون: University of Melbourne, Bio21 Molecular Science & Biotechnology Institute [Melbourne] (School of Chemistry), Faculty of Science [Melbourne], University of Melbourne-University of Melbourne, Institut Curie [Paris], Biologie Cellulaire et Cancer, Institut Curie [Paris]-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2020, 31 (1), pp.27-44. ⟨10.1091/mbc.E19-09-0487⟩

مصطلحات موضوعية: green fluorescent protein, PM, day in vitro, Golgi Apparatus, beta site APP-cleaving enzyme, amyloid precursor protein, plasma membrane, Cell membrane, Amyloid beta-Protein Precursor, 0302 clinical medicine, Cell Movement, Arf1, Amyloid precursor protein, Aspartic Acid Endopeptidases, Arf4, Neurons, 0303 health sciences, biology, trans-Golgi network, BACE1, Articles, primary neurons Abbreviations: Aβ, Alzheimer's disease, Endocytosis, Cell biology, Transport protein, anterograde transport, Protein Transport, endoplasmic reticulum, medicine.anatomical_structure, Cell Biology of Disease, small GTPase, TGN, symbols, beta-amyloid peptide, retention using selective hooks, Endosome, amyloid precursor protein (APP), membrane transport, Endosomes, total internal reflection fluorescence microscopy, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, TIRF, GFP, 03 medical and health sciences, symbols.namesake, Alzheimer Disease, mental disorders, medicine, Humans, RUSH, Molecular Biology, Secretory pathway, 030304 developmental biology, Amyloid beta-Peptides, beta-secretase 1 (BACE1), Cell Membrane, AD, Cell Biology, Golgi apparatus, AP-1, transferrin receptor, DIV, AP-4, ER, TfR, amyloid beta (Aβ), biology.protein, Amyloid Precursor Protein Secretases, APP, Amyloid precursor protein secretase, 030217 neurology & neurosurgery, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533558c99378654d3555b0935e6e830a
https://hal.archives-ouvertes.fr/hal-02986333/document

المؤلفون: Brian D. Green, Xiaobei Pan

المصدر: Pan, X & Green, B D 2018, ' Temporal Effects of Neuron-specific Beta-secretase 1 (BACE1) Knock-in on the Mouse Brain Metabolome : Implications for Alzheimer's Disease ', Neuroscience, pp. 1-15 . https://doi.org/10.1016/j.neuroscience.2018.11.031
Pan, X & Green, B D 2019, ' Temporal Effects of Neuron-specific beta-secretase 1 (BACE1) Knock-in on the Mouse Brain Metabolome: Implications for Alzheimer's Disease ', Neuroscience, vol. 397, pp. 138-146 . https://doi.org/10.1016/j.neuroscience.2018.11.031

مصطلحات موضوعية: PLB4, 0301 basic medicine, Aging, medicine.medical_specialty, beta secretase 1 (BACE1), brain, Neuroscience(all), Carnosine, Mice, Transgenic, Pathogenesis, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Alzheimer Disease, Gene knockin, Internal medicine, Extracellular, Metabolome, medicine, Animals, Aspartic Acid Endopeptidases, Humans, metabolites, Neurons, biology, General Neuroscience, Wild type, Brain, Alzheimer's disease, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Beta-secretase 1, Endocrinology, chemistry, biology.protein, Female, Neuron, Amyloid Precursor Protein Secretases, 030217 neurology & neurosurgery

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c681558503b7054e44018766b67edcc6
https://pure.qub.ac.uk/en/publications/temporal-effects-of-neuronspecific-betasecretase-1-bace1-knockin-on-the-mouse-brain-metabolome--implications-for-alzheimers-disease(88d735ed-087c-4aca-8f4f-d52b8599c02c).html

المؤلفون: Daniel Fleck, Camilla Giudici, Matthias Voss, Michael Willem, Dieter Edbauer, Elisabeth Kremmer, Moritz J. Rossner, Martina Haug-Kröper, Akio Fukumori, Christian Haass, Harald Steiner, Ben Brankatschk, Benjamin M. Schwenk, Regina Fluhrer, Heike Hampel

المصدر: The journal of biological chemistry 291(1), 318-333 (2015). doi:10.1074/jbc.M115.697995
J. Biol. Chem. 291, 318-333 (2016)

مصطلحات موضوعية: 0301 basic medicine, metabolism [Peptide Hydrolases], Biochemistry, Substrate Specificity, metabolism [Neuregulin-1], Amyloid precursor protein, Aspartic Acid Endopeptidases, genetics [Schizophrenia], Peptide sequence, metabolism [C-Peptide], Neurons, C-Peptide, biology, medicine.diagnostic_test, Molecular Bases of Disease, metabolism [Aspartic Acid Endopeptidases], Adam, Alzheimer Disease, Amyloid-beta (ab), Beta-secretase 1 (bace1), Gamma-secretase, Neurodegeneration, Transmembrane domain, metabolism [Neurons], ddc:540, genetics [Polymorphism, Single Nucleotide], Signal peptide, Proteases, Neuregulin-1, Proteolysis, Molecular Sequence Data, chemistry [Peptides], genetics [Mutation], Polymorphism, Single Nucleotide, Regulated Intramembrane Proteolysis, genetics [Amino Acid Substitution], 03 medical and health sciences, mental disorders, medicine, Animals, Humans, ddc:610, Amino Acid Sequence, Molecular Biology, enzymology [Cell Membrane], Cell Membrane, Cell Biology, Sheddase, Protein Structure, Tertiary, Rats, HEK293 Cells, 030104 developmental biology, Amino Acid Substitution, genetics [Aspartic Acid Endopeptidases], Mutation, Schizophrenia, biology.protein, Peptides, Peptide Hydrolases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35971ce3c86b99465f7c5da97b1b0cb9
https://doi.org/10.1074/jbc.m115.697995

المؤلفون: Selene Lomoio, Sylvia Lombardo, WonHee Kim, Jinghui Dong, Giuseppina Tesco, Rachel Willen, Liang Ma, Philip G. Haydon

المصدر: Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-22 (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Amyloid-beta (Aβ), Down syndrome, Hippocampal formation, lcsh:Geriatrics, lcsh:RC346-429, CHL1, Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Golgi-localized γ-ear-containing ARF binding protein 3 (GGA3), Amyloid precursor protein, Aspartic Acid Endopeptidases, Mice, Knockout, biology, Chemistry, Brain, Middle Aged, 3. Good health, Female, Alzheimer's disease, Research Article, Adult, medicine.medical_specialty, Amyloid beta, Clathrin, Beta-secretase 1 (BACE1), 03 medical and health sciences, Cellular and Molecular Neuroscience, In vivo, Alzheimer Disease, Internal medicine, mental disorders, medicine, Animals, Humans, Amyloid precursor protein (APP), Molecular Biology, lcsh:Neurology. Diseases of the nervous system, Cell adhesion molecule L1 like protein (CHL1), Aged, Amyloid beta-Peptides, medicine.disease, Molecular medicine, lcsh:RC952-954.6, Adaptor Proteins, Vesicular Transport, 030104 developmental biology, Endocrinology, biology.protein, Neurology (clinical), Amyloid Precursor Protein Secretases, Cell Adhesion Molecules, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27429ef1be7c3dfb6e97491522e5aa46
http://europepmc.org/articles/PMC5796504

المؤلفون: 아흐메드

المساهمون: 한호재, Amr Ahmed Gabr, 수의과대학 수의학과

مصطلحات موضوعية: Alzheimer’s disease, Ethanol, Amyloidogenesis, Beta secretase 1 (BACE1), Eukaryotic initiation factor 2α (eIF2α), Prostaglandin E2 (PGE2), 636.089

وصف الملف: application/pdf; 3579732 bytes

Relation: 000000145138; https://hdl.handle.net/10371/137924

الاتاحة: https://hdl.handle.net/10371/137924