المؤلفون: Anthony J. F. Reardon, Reza Farmahin, Andrew Williams, Matthew J. Meier, Gregory C. Addicks, Carole L. Yauk, Geronimo Matteo, Ella Atlas, Joshua Harrill, Logan J. Everett, Imran Shah, Richard Judson, Sreenivasa Ramaiahgari, Stephen S. Ferguson, Tara S. Barton-Maclaren

المصدر: Frontiers in Toxicology, Vol 5 (2023)

مصطلحات موضوعية: new approach methods, NAMs, transcriptomics, benchmark dose (BMD) modeling, in vitro to in vivo extrapolation (IVIVE), chemical safety, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2023.1194895/full; https://doaj.org/toc/2673-3080

URL الوصول: https://doaj.org/article/96854b10d2a34e91b4c5508eac32b91d

المؤلفون: Anthony J. F. Reardon, Reza Farmahin, Andrew Williams, Matthew J. Meier, Gregory C. Addicks, Carole L. Yauk, Geronimo Matteo, Ella Atlas, Joshua Harrill, Logan J. Everett, Imran Shah, Richard Judson, Sreenivasa Ramaiahgari, Stephen S. Ferguson, Tara S. Barton-Maclaren

مصطلحات موضوعية: Pharmacology, Toxicology, Immunology, Toxicology (incl. Clinical Toxicology), Nanotoxicology, Health and Safety, new approach methods, NAMs, transcriptomics, benchmark dose (BMD) modeling, in vitro to in vivo extrapolation (IVIVE), chemical safety

Relation: https://figshare.com/articles/dataset/Table1_From_vision_toward_best_practices_Evaluating_in_vitro_transcriptomic_points_of_departure_for_application_in_risk_assessment_using_a_uniform_workflow_docx/23086166

الاتاحة: https://doi.org/10.3389/ftox.2023.1194895.s002
https://figshare.com/articles/dataset/Table1_From_vision_toward_best_practices_Evaluating_in_vitro_transcriptomic_points_of_departure_for_application_in_risk_assessment_using_a_uniform_workflow_docx/23086166

المؤلفون: William Rish, Chad M. Thompson, Caroline Ring, Laurie C. Haws, John M. Cullen, Seneca Fitch

المصدر: Journal of Applied Toxicology

مصطلحات موضوعية: GenX, Hydrocarbons, Fluorinated, benchmark dose (BMD) modeling, Perfluorinated compound, 010501 environmental sciences, Toxicology, 01 natural sciences, Lethal Dose 50, 03 medical and health sciences, chemistry.chemical_compound, Statistics, Animals, Humans, Narrow range, Maximum Contaminant Level, Processing aid, Research Articles, reference dose (RfD), 030304 developmental biology, 0105 earth and related environmental sciences, No-Observed-Adverse-Effect Level, per‐ and polyfluoroalkyl substances (PFAS), 0303 health sciences, Reference dose, Drinking Water, risk assessment, Reference Standards, United States, Rats, Benchmarking, chemistry, Models, Animal, Environmental science, Mammalian toxicity, Propionates, Water Pollutants, Chemical, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921aab73b14dd7aed1b5b039ab1aeea7
https://doi.org/10.1002/jat.3812

المؤلفون: Chad M. Thompson, Deborah M. Proctor, Seneca Harvey, Mina Suh, Mark A. Harris, Julia E. Rager, Christopher R. Kirman, Laurie C. Haws, Sean M. Hays

المصدر: Journal of Applied Toxicology

مصطلحات موضوعية: Chromium, Male, 0301 basic medicine, margin of exposure (MOE), benchmark dose (BMD) modeling, Administration, Oral, 010501 environmental sciences, Pharmacology, Toxicology, 01 natural sciences, Mice, chemistry.chemical_compound, Medicine, Bioassay, Research Articles, reference dose (RfD), Reference Standards, Calibration, Biological Assay, Environmental Pollutants, Female, medicine.symptom, Research Article, Physiologically based pharmacokinetic modelling, Carcinogenicity Tests, hexavalent chromium Cr(VI), Models, Biological, Risk Assessment, Lesion, 03 medical and health sciences, mode of action, Species Specificity, Pharmacokinetics, Intestinal Neoplasms, Animals, Humans, United States Environmental Protection Agency, Hexavalent chromium, Mode of action, Carcinogen, 0105 earth and related environmental sciences, No-Observed-Adverse-Effect Level, Reference dose, Dose-Response Relationship, Drug, business.industry, United States, Rats, 030104 developmental biology, chemistry, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc37e0de19993cad867f3a8fe8c30d09
https://doi.org/10.1002/jat.3545

المؤلفون: Chad M. Thompson, Mina Suh, Mark A. Harris, J. Gregory Hixon, Deborah M. Proctor, Christopher R. Kirman, Sean M. Hays, Laurie C. Haws

المصدر: Journal of Applied Toxicology

مصطلحات موضوعية: Chromium, Male, No-observed-adverse-effect level, Carcinogenicity Tests, Intestinal Neoplasm, benchmark dose (BMD) modeling, Ileum, intestinal cancer, Pharmacology, Toxicology, hexavalent chromium Cr(VI), Models, Biological, Jejunum, chemistry.chemical_compound, Mice, Sex Factors, mode of action, Intestinal Neoplasms, medicine, cancer reference dose (RfD), Animals, Humans, Hexavalent chromium, United States Environmental Protection Agency, Toxicity Tests, Chronic, Research Articles, Reference dose, No-Observed-Adverse-Effect Level, Hyperplasia, Dose-Response Relationship, Drug, Chemistry, constrained nonlinear regression, Drinking Water, risk assessment, Reference Standards, Small intestine, United States, medicine.anatomical_structure, Immunology, Duodenum, Female, Water Pollutants, Chemical

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc29be33b9b30a1fe576584e66119a4
http://europepmc.org/articles/PMC4282340