المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/journal_contribution/General_procedure_for_the_synthesis_of_i_N_i_sup_4_sup_-acylated_nucleosides_/24690629

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.s001
https://figshare.com/articles/journal_contribution/General_procedure_for_the_synthesis_of_i_N_i_sup_4_sup_-acylated_nucleosides_/24690629

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/journal_contribution/Western_blot_analysis_of_YqfB_and_D8_RL_/24690635

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.s002
https://figshare.com/articles/journal_contribution/Western_blot_analysis_of_YqfB_and_D8_RL_/24690635

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/journal_contribution/Proteomic_analysis_of_YqfB_and_D8_RL_/24690638

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.s003
https://figshare.com/articles/journal_contribution/Proteomic_analysis_of_YqfB_and_D8_RL_/24690638

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/figure/Substrates_of_YqfB_and_D8_RL_amidohydrolases_/24690653

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.g002
https://figshare.com/articles/figure/Substrates_of_YqfB_and_D8_RL_amidohydrolases_/24690653

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/figure/Graphical_representation_of_YqfB_D8_RL_enzyme-mediated_activation_of_an_anticancer_prodrug_/24690647

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.g001
https://figshare.com/articles/figure/Graphical_representation_of_YqfB_D8_RL_enzyme-mediated_activation_of_an_anticancer_prodrug_/24690647

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/figure/Substrate_specificity_of_YqfB_and_D8_RL_amidohydrolases_/24690656

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.g003
https://figshare.com/articles/figure/Substrate_specificity_of_YqfB_and_D8_RL_amidohydrolases_/24690656

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/figure/MTT_assay_of_the_HCT116_cell_lines_expressing_YqfB_or_D8_RL_after_exposure_to_10_M_of_prodrugs_/24690671

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.g007
https://figshare.com/articles/figure/MTT_assay_of_the_HCT116_cell_lines_expressing_YqfB_or_D8_RL_after_exposure_to_10_M_of_prodrugs_/24690671

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/figure/Fig_4_-/24690659

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.g004
https://figshare.com/articles/figure/Fig_4_-/24690659

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/figure/MTT_assay_of_cell_lines_expressing_YqfB_and_D8_RL_following_treatment_of_prodrugs_/24690668

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.g006
https://figshare.com/articles/figure/MTT_assay_of_cell_lines_expressing_YqfB_and_D8_RL_following_treatment_of_prodrugs_/24690668

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/figure/Confirmation_of_i_yqfB_i_and_i_D8_RL_i_expression_in_HCT116_and_MCF7_cells_by_real_time_PCR_/24690662

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.g005
https://figshare.com/articles/figure/Confirmation_of_i_yqfB_i_and_i_D8_RL_i_expression_in_HCT116_and_MCF7_cells_by_real_time_PCR_/24690662

المؤلفون: Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Pharmacology, Biotechnology, Immunology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, target cancer cells, potent cytotoxin exclusively, eukaryotic cancer cells, cancer treatment based, bacterial amidohydrolase genes, suitable enzyme variants, activate novel prodrugs, div >< p, bacterial amidohydrolases yqfb, bacterial amidohydrolases, based prodrugs, novel prodrugs, bacterial yqfb, >< sup, novel enzyme, potential prodrugs, stably express, significant decrease, selected several

Relation: https://figshare.com/articles/figure/MTT_assay_of_HCT116_cell_line_following_treatment_of_hydrolysis_products_derived_from_the_complex_prodrug_5-fluoro-_i_N_i_sup_4_sup_-_3-indolepropionyl_cytidine_/24690674

الاتاحة: https://doi.org/10.1371/journal.pone.0294696.g008
https://figshare.com/articles/figure/MTT_assay_of_HCT116_cell_line_following_treatment_of_hydrolysis_products_derived_from_the_complex_prodrug_5-fluoro-_i_N_i_sup_4_sup_-_3-indolepropionyl_cytidine_/24690674