المؤلفون: Shira Merzbach, Amnon Hoffman, Philip Lazarovici, Chaim Gilon, Radgonde Amer

المصدر: Pharmaceutics, Vol 16, Iss 6, p 723 (2024)

مصطلحات موضوعية: backbone cyclization, thiourea-bridged, peptomer, calreticulin, experimental autoimmune uveoretinitis, inflammatory autoimmune diseases, Pharmacy and materia medica, RS1-441

Relation: https://www.mdpi.com/1999-4923/16/6/723; https://doaj.org/toc/1999-4923; https://doaj.org/article/834edcd997b149c6b94d34589b80d8ed

الاتاحة: https://doi.org/10.3390/pharmaceutics16060723
https://doaj.org/article/834edcd997b149c6b94d34589b80d8ed

المؤلفون: Dias, Susana Filipa Almeida

المساهمون: Veiga, Ana Salomé Rocha do Nascimento, Repositório da Universidade de Lisboa

مصطلحات موضوعية: Biofilmes bacterianos, Péptidos antimicrobianos, Combinação de diferentes terapias, Ciclização de sequências peptídicas, Bacterial biofilms, Antimicrobial peptides, Combination therapy, Backbone cyclization, Domínio/Área Científica::Ciências Médicas::Ciências da Saúde

وصف الملف: application/pdf

الاتاحة: http://hdl.handle.net/10451/63711

المؤلفون: Muhammad, Taj, Strömstedt, Adam A., Docent, 1977, Gunasekera, Sunithi, 1977, Göransson, Ulf, 1970

المصدر: Biomedicines. 11(2)

مصطلحات موضوعية: antimicrobial peptides, backbone cyclization, cathelicidin, LL-37, KR-12

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-498547
https://doi.org/10.3390/biomedicines11020504
https://uu.diva-portal.org/smash/get/diva2:1745110/FULLTEXT01.pdf

المؤلفون: Shulamit Fluss Ben-Uliel, Faten Habrat Zoabi, Moriya Slavin, Hadas Sibony-Benyamini, Nir Kalisman, Nir Qvit

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6076

مصطلحات موضوعية: Pink1, mitophagy, bioactive peptides, peptidomimetics, backbone cyclization, protein-protein interactions, protein-peptide interactions, therapeutic peptides, mitochondria, molecular probes

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Bioactives and Nutraceuticals; https://dx.doi.org/10.3390/ijms23116076

الاتاحة: https://doi.org/10.3390/ijms23116076

المؤلفون: Alaa Talhami, Avi Swed, Shmuel Hess, Oded Ovadia, Sarit Greenberg, Adi Schumacher-Klinger, David Rosenthal, Deborah E. Shalev, Mattan Hurevich, Philip Lazarovici, Amnon Hoffman, Chaim Gilon

المصدر: Frontiers in Chemistry, Vol 8 (2020)

مصطلحات موضوعية: reductive alkylation, backbone cyclization, cycloscan, TAPS, peripheral painkiller, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fchem.2020.532577/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/214c0a356de24363ad9340767112adf5

المؤلفون: Koki Shinbara, Wenyu Liu, Renier Herman Pieter van Neer, Takayuki Katoh, Hiroaki Suga

المصدر: Frontiers in Chemistry, Vol 8 (2020)

مصطلحات موضوعية: non-proteinogenic amino acid, backbone macrocyclic peptide, enzymatic peptide backbone cyclization, peptide library, OBOC screening, SICLOPPS, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fchem.2020.00447/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/66e75635d61f4aa89128c4cd9f5d487d

المؤلفون: Schmidt, Marcel, Huang, Yen-Hua, Texeira de Oliveira, Eduardo F, Toplak, Ana, Wijma, Hein J, Janssen, Dick B, van Maarseveen, Jan H, Craik, David J, Nuijens, Timo

المصدر: Schmidt , M , Huang , Y-H , Texeira de Oliveira , E F , Toplak , A , Wijma , H J , Janssen , D B , van Maarseveen , J H , Craik , D J & Nuijens , T 2019 , ' Efficient Enzymatic Cyclization of Disulfide-rich Peptides using Peptide Ligases ' , ChemBioChem , vol. 20 , no. 12 , pp. 1524-1529 . https://doi.org/10.1002/cbic.201900033

مصطلحات موضوعية: RECOMBINANT EXPRESSION, BACKBONE CYCLIZATION, MACROCYCLIC PEPTIDES, CIRCULAR PROTEINS, MEDIATED LIGATION, CYCLOTIDES, BIOSYNTHESIS, TEMPLATES, ESTERS, RTD-1

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/03b2005c-6a70-4aa9-bf05-829e34985bb6
https://research.rug.nl/en/publications/03b2005c-6a70-4aa9-bf05-829e34985bb6
https://doi.org/10.1002/cbic.201900033
https://pure.rug.nl/ws/files/99790472/Schmidt_et_al_2019_ChemBioChem.pdf

المؤلفون: Sukumaran, Surya, Tan, Mingdian, Ben-Uliel, Shulamit Fluss, Zhang, Hui, De Zotti, Marta, Chua, Mei-Sze, So, Samuel K., Qvit, Nir

المساهمون: Sukumaran, Surya, Tan, Mingdian, Ben-Uliel, Shulamit Flu, Zhang, Hui, De Zotti, Marta, Chua, Mei-Sze, So, Samuel K., Qvit, Nir

مصطلحات موضوعية: Backbone cyclization, CD (Circular dichroism), Cdc37 (cell division cycle 37), Colocalization, Cyclic peptidomimetic, Field effect biosensing (FEB), HCC (hepatocellular carcinoma), Hsp90 (heat shock protein 90), Peptide probe, Peptide, Peptidomimetic, Pre-cyclic peptidomimetic, Protein-protein interaction

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/37304004; info:eu-repo/semantics/altIdentifier/wos/WOS:001016523200001; volume:21; firstpage:3159; lastpage:3172; numberofpages:14; journal:COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL; https://hdl.handle.net/11577/3505028; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85163495536

الاتاحة: https://hdl.handle.net/11577/3505028
https://doi.org/10.1016/j.csbj.2023.05.023

المؤلفون: Katsiaryna Tarasava, Silke Johannsen, Eva Freisinger

المصدر: Molecules, Vol 18, Iss 11, Pp 14414-14429 (2013)

مصطلحات موضوعية: plant metallothioneins, metal-thiolate cluster, backbone cyclization, flexibility reduction, NMR spectroscopy, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/18/11/14414; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/c593beb69e884e84a0cb68a1a27005ef

المؤلفون: Dias, Susana Filipa Almeida

المساهمون: Veiga, Ana Salomé Rocha do Nascimento

مصطلحات موضوعية: Biofilmes bacterianos, Péptidos antimicrobianos, Combinação de diferentes terapias, Ciclização de sequências peptídicas, Bacterial biofilms, Antimicrobial peptides, Combination therapy, Backbone cyclization, Domínio/Área Científica::Ciências Médicas::Ciências da Saúde

Relation: info:eu-repo/grantAgreement/FCT/OE/PD%2FBD%2F114425%2F2016/PT; http://hdl.handle.net/10451/63711; 101517700

الاتاحة: http://hdl.handle.net/10451/63711

المؤلفون: Wenyu Liu, Hiroaki Suga, Takayuki Katoh, Renier Herman Pieter van Neer, Koki Shinbara

المصدر: Frontiers in Chemistry
Frontiers in Chemistry, Vol 8 (2020)

مصطلحات موضوعية: Membrane permeability, Peptide, 02 engineering and technology, Computational biology, Review, 010402 general chemistry, 01 natural sciences, Chemical synthesis, peptide library, lcsh:Chemistry, Macrocyclic peptide, mRNA display, Peptide library, OBOC screening, chemistry.chemical_classification, Chemistry, in vitro screening, General Chemistry, 021001 nanoscience & nanotechnology, Genetic code, SICLOPPS, 0104 chemical sciences, lcsh:QD1-999, enzymatic peptide backbone cyclization, 0210 nano-technology, Peptide drug, non-proteinogenic amino acid, backbone macrocyclic peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcbf223c87d56ba40eb54786e7ccfec
https://pubmed.ncbi.nlm.nih.gov/32626683

المؤلفون: Department of Pharmaceutics, School of Pharmacy, The Hebrew University of Jerusalem, PO Box 12065, Jerusalem 91120, Israel ( host institution ), Ovadia, Oded ( author ), Linde, Yaniv ( author ), Haskell-Luevano, Carrie ( author ), Dirain, Marvin L. ( author ), Sheynis, Tanya ( author ), Jelinek, Raz ( author ), Gilon, Chaim ( author ), Hoffman, Amnon ( author )

مصطلحات موضوعية: Peptomers, Backbone cyclization, Melanocortin

وصف الملف: Pages 580-589

Relation: Bioorganic & Medicinal Chemistry; S0968-0896(09)01094-3; http://ufdc.ufl.edu/LS00524195/00001

الاتاحة: https://doi.org/10.1016/j.bmc.2009.12.010
http://ufdc.ufl.edu/LS00524195/00001

المؤلفون: Malik, Uru, Chan, Lai Yue, Cai, Minying, Hruby, Victor J., Kaas, Quentin, Daly, Norelle L., Craik, David J.

مصطلحات موضوعية: Antagonist, Backbone cyclization, Binding, Frog‐skin peptides, Melanocortin

Relation: orcid:0000-0002-9346-2487; orcid:0000-0001-9988-6152; orcid:0000-0003-0007-6796; FL150100146 %7C FT1100100226; APP1028509; GM108040

الاتاحة: https://espace.library.uq.edu.au/view/UQ:21270f3

المؤلفون: Jan H. van Maarseveen, Ana Toplak, Marcel Schmidt, Hein J. Wijma, Yen-Hua Huang, Dick B. Janssen, Eduardo F Texeira de Oliveira, David J. Craik, Timo Nuijens

المساهمون: Biotechnology, Synthetic Organic Chemistry (HIMS, FNWI)

المصدر: ChemBioChem, 20(12), 1524-1529. WILEY-V C H VERLAG GMBH
ChemBioChem, 20(12), 1524-1529. Wiley-VCH Verlag

مصطلحات موضوعية: CYCLOTIDES, MACROCYCLIC PEPTIDES, RECOMBINANT EXPRESSION, Peptide, BACKBONE CYCLIZATION, 010402 general chemistry, 01 natural sciences, Biochemistry, Defensins, chemistry.chemical_compound, Biosynthesis, Cyclotides, MEDIATED LIGATION, BIOSYNTHESIS, TEMPLATES, Peptide Synthases, Molecular Biology, Plant Proteins, chemistry.chemical_classification, DNA ligase, 010405 organic chemistry, RTD-1, Organic Chemistry, Disulfide bond, ESTERS, CIRCULAR PROTEINS, Combinatorial chemistry, 0104 chemical sciences, Cyclotide, Folding (chemistry), Enzyme, chemistry, Cyclization, Molecular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642cfa74c4bd31a3ac29fdee594635b5
https://research.rug.nl/en/publications/03b2005c-6a70-4aa9-bf05-829e34985bb6

المؤلفون: Koki Shinbara, Wenyu Liu, Renier Herman Pieter van Neer, Takayuki Katoh, Hiroaki Suga

مصطلحات موضوعية: Biochemistry, Environmental Chemistry, Geochemistry, Organic Chemistry, Inorganic Chemistry, Nuclear Chemistry, Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics), Medical Biochemistry and Metabolomics not elsewhere classified, Food Chemistry and Molecular Gastronomy (excl. Wine), Analytical Biochemistry, Cell Neurochemistry, Enzymes, Electroanalytical Chemistry, Analytical Chemistry not elsewhere classified, Organic Green Chemistry, Physical Organic Chemistry, Catalysis and Mechanisms of Reactions, Environmental Chemistry (incl. Atmospheric Chemistry), non-proteinogenic amino acid, backbone macrocyclic peptide, enzymatic peptide backbone cyclization, peptide library, OBOC screening, SICLOPPS, in vitro screening

Relation: https://figshare.com/articles/dataset/Table_1_Methodologies_for_Backbone_Macrocyclic_Peptide_Synthesis_Compatible_With_Screening_Technologies_pdf/12503828

الاتاحة: https://doi.org/10.3389/fchem.2020.00447.s001
https://figshare.com/articles/dataset/Table_1_Methodologies_for_Backbone_Macrocyclic_Peptide_Synthesis_Compatible_With_Screening_Technologies_pdf/12503828

المؤلفون: Alaa Talhami, Avi Swed, Shmuel Hess, Oded Ovadia, Sarit Greenberg, Adi Schumacher-Klinger, David Rosenthal, Deborah E. Shalev, Mattan Hurevich, Philip Lazarovici, Amnon Hoffman, Chaim Gilon

مصطلحات موضوعية: Biochemistry, Environmental Chemistry, Geochemistry, Organic Chemistry, Inorganic Chemistry, Nuclear Chemistry, Medical Biochemistry: Proteins and Peptides (incl. Medical Proteomics), Medical Biochemistry and Metabolomics not elsewhere classified, Food Chemistry and Molecular Gastronomy (excl. Wine), Analytical Biochemistry, Cell Neurochemistry, Enzymes, Electroanalytical Chemistry, Analytical Chemistry not elsewhere classified, Organic Green Chemistry, Physical Organic Chemistry, Catalysis and Mechanisms of Reactions, Environmental Chemistry (incl. Atmospheric Chemistry), reductive alkylation, backbone cyclization, cycloscan, TAPS, peripheral painkiller

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Cyclizing_Painkillers_Development_of_Backbone-Cyclic_TAPS_Analogs_PDF/13226855

الاتاحة: https://doi.org/10.3389/fchem.2020.532577.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Cyclizing_Painkillers_Development_of_Backbone-Cyclic_TAPS_Analogs_PDF/13226855

المؤلفون: Schmidt, Marcel, Huang, Yen-Hua, de Oliveira, Eduardo F. Texeira, Toplak, Ana, Wijma, Hein J., Janssen, Dick B., van Maarseveen, Jan H., Craik, David J., Nuijens, Timo

مصطلحات موضوعية: Recombinant Expression, Backbone Cyclization, Macrocyclic Peptides, Circular Proteins, Mediated Ligation, Cyclotides, Biosynthesis, Templates, Esters, Rtd-1, 1303 Biochemistry, 1312 Molecular Biology, 1313 Molecular Medicine, 1605 Organic Chemistry

Relation: orcid:0000-0001-6937-2660; orcid:0000-0003-0007-6796; FL150100146

الاتاحة: https://espace.library.uq.edu.au/view/UQ:dde8c70/UQdde8c70_OA.pdf
https://espace.library.uq.edu.au/view/UQ:dde8c70

المؤلفون: Akcan, Muharrem, Craik, David J.

المساهمون: Glenn F. King

مصطلحات موضوعية: Nicotinic Acetylcholine-Receptors, Alpha-Conotoxin Auib, Native Chemical Ligation, Disulfide Bond Isomers, Cyclic Cystine Knot, Backbone Cyclization, Norepinephrine Transporter, Calcium-Channels, Gaba(B) Receptor, Neuropathic Pain

Relation: orcid:0000-0003-0007-6796

الاتاحة: https://espace.library.uq.edu.au/view/UQ:355544

المؤلفون: Kwon, Soohyun, Bosmans, Frank, Kaas, Quentin, Cheneval, Olivier, Conibear, Anne C, Rosengren, K Johan, Wang, Conan K, Schroeder, Christina I, Craik, David J

المصدر: BIOTECHNOLOGY AND BIOENGINEERING ; ISSN: 0006-3592 ; ISSN: 1097-0290

مصطلحات موضوعية: Biology and Life Sciences, kappa-PVIIA, inhibitory cystine knot, cyclization, sortase A, KAPPA-CONOTOXIN PVIIA, SHAKER K+ CHANNEL, GATED POTASSIUM CHANNEL, SODIUM-CHANNEL, STRUCTURAL MOTIF, BACKBONE CYCLIZATION, CYCLIC-PEPTIDES, FORCE-FIELD, RAT-BRAIN, KALATA B1

Relation: https://biblio.ugent.be/publication/8584508; http://hdl.handle.net/1854/LU-8584508; http://dx.doi.org/10.1002/bit.25993

الاتاحة: https://biblio.ugent.be/publication/8584508
http://hdl.handle.net/1854/LU-8584508
https://doi.org/10.1002/bit.25993

المؤلفون: Silke Johannsen, Eva Freisinger, Katsiaryna Tarasava

المساهمون: University of Zurich

المصدر: Molecules
Volume 18
Issue 11
Pages 14414-14429
Molecules, Vol 18, Iss 11, Pp 14414-14429 (2013)

مصطلحات موضوعية: 10120 Department of Chemistry, Circular dichroism, 1601 Chemistry (miscellaneous), metal-thiolate cluster, Analytical chemistry, 3003 Pharmaceutical Science, backbone cyclization, Pharmaceutical Science, 010402 general chemistry, 01 natural sciences, Article, Analytical Chemistry, Ion, lcsh:QD241-441, 03 medical and health sciences, NMR spectroscopy, lcsh:Organic chemistry, Drug Discovery, 540 Chemistry, Peptide bond, Metallothionein, Physical and Theoretical Chemistry, Nuclear Magnetic Resonance, Biomolecular, flexibility reduction, Triticum, 030304 developmental biology, 0303 health sciences, 1602 Analytical Chemistry, Chemistry, Metal binding, 3002 Drug Discovery, Organic Chemistry, Nuclear magnetic resonance spectroscopy, Solution structure, 0104 chemical sciences, Crystallography, Chemistry (miscellaneous), 1313 Molecular Medicine, Domain (ring theory), plant metallothioneins, Molecular Medicine, 1606 Physical and Theoretical Chemistry, 1605 Organic Chemistry

وصف الملف: application/pdf; Molecules_2013_14414_14429.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e807af4772619142b61b9b60395e574a
https://pubmed.ncbi.nlm.nih.gov/24284492