المؤلفون: Grigorios Nikitidis (4508872), Anna-Carin C. Carlsson (3945737), Staffan Karlsson (1443904), Andrew D. Campbell (9772366), Calum Cook (3927476), Kuangchu Dai (6904937), Hans Emtenäs (1684684), Anna C. Jonson (4007507), Hanna Leek (4007504), Marcus Malmgren (6278591), Štefan Moravčík (6933980), Subhash Pithani (6919280), Matthew R. Tatton (1304370), Hucheng Zhao (6852461), Kristina Öhlén (11326106)

مصطلحات موضوعية: Biochemistry, Pharmacology, Sociology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, multigram synthesis, drug development projects, API purification, drug candidates, Chromatographic Challenges, sequence, Multigram Manufacture, atropisomer separation, chiral axis, biaryl fragment, KRAS G 12C Inhibitors, Suzuki reaction

Relation: https://figshare.com/articles/journal_contribution/Synthetic_and_Chromatographic_Challenges_and_Strategies_for_Multigram_Manufacture_of_KRAS_sup_G12C_sup_Inhibitors/16432385

الاتاحة: https://doi.org/10.1021/acs.oprd.1c00179.s001

المؤلفون: Ling Zhang, Yue Hu, Elizabeth Galella, Frank P. Tomasella, William P. Fish

المصدر: Journal of Pharmaceutical Analysis, Vol 7, Iss 3, Pp 156-162 (2017)

مصطلحات موضوعية: Atropisomer separation, Chiral HPLC, Thermodynamic parameters, β-cyclodextrin stationary phase, Chiral separation mechanism, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095177917300217; https://doaj.org/toc/2095-1779

URL الوصول: https://doaj.org/article/b7a3907b4c9346a98d0c8be851f8b6ab

المؤلفون: Alain Berthod, Daniel W. Armstrong, Hongyin Gao, László Kürti, Lillian A. Frink, Qing-Long Xu

المساهمون: Department of Chemistry, University of Texas at Arlington [Arlington], Chromatography & Hyphenated Techniques - Chromatographie et techniques couplées, Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Biosci Res Collaborat, Rice University [Houston], Daniel W. Armstrong thanks the Robert A. Welch foundation (Y-0026) and the University of Texas at Arlington for financial support.

المصدر: Journal of Liquid Chromatography and Related Technologies
Journal of Liquid Chromatography and Related Technologies, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 2016, 39 (15), pp.710-717. ⟨10.1080/10826076.2016.1234395⟩

مصطلحات موضوعية: Heptane, Atropisomer, Chromatography, Chemical substance, Atropisomer separation, superficially porous particles, 010405 organic chemistry, Butanol, 010401 analytical chemistry, Clinical Biochemistry, Pharmaceutical Science, Alcohol, 01 natural sciences, Biochemistry, cyclofructan selectors, 0104 chemical sciences, Analytical Chemistry, chemistry.chemical_compound, chemistry, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, 2-naphthol phenyl derivatives, 2-Naphthol, Derivative (chemistry), Isopropyl

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c8b2e8cd52699bae274d2cb80e8c28
https://doi.org/10.1080/10826076.2016.1234395