المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/journal_contribution/Supplementary_material_/24601541

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.s001
https://figshare.com/articles/journal_contribution/Supplementary_material_/24601541

المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/figure/Simulated_drug_exposures_after_administration_of_WHO_recommended_doses_and_weight_bands_/24601544

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.g001
https://figshare.com/articles/figure/Simulated_drug_exposures_after_administration_of_WHO_recommended_doses_and_weight_bands_/24601544

المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/figure/Simulated_rifampicin_exposures_after_adding_75_mg_or_150_mg_to_the_WHO_recommended_doses_and_weight_bands_/24601547

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.g002
https://figshare.com/articles/figure/Simulated_rifampicin_exposures_after_adding_75_mg_or_150_mg_to_the_WHO_recommended_doses_and_weight_bands_/24601547

المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/figure/Concentration_versus_time_plots_for_simulated_steady-state_drug_concentrations_/24601550

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.g003
https://figshare.com/articles/figure/Concentration_versus_time_plots_for_simulated_steady-state_drug_concentrations_/24601550

المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/dataset/Patient_characteristics_stratified_by_study_/24601562

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.t002
https://figshare.com/articles/dataset/Patient_characteristics_stratified_by_study_/24601562

المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/dataset/Final_model_parameters_for_rifampicin_isoniazid_and_pyrazinamide_/24601565

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.t003
https://figshare.com/articles/dataset/Final_model_parameters_for_rifampicin_isoniazid_and_pyrazinamide_/24601565

المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/figure/Simulated_tuberculosis_drug_exposures_achieved_in_children_on_lopinavir_ritonavir_vs_those_not_on_lopinavir_ritonavir_/24601553

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.g004
https://figshare.com/articles/figure/Simulated_tuberculosis_drug_exposures_achieved_in_children_on_lopinavir_ritonavir_vs_those_not_on_lopinavir_ritonavir_/24601553

المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/figure/Plot_of_maturation_of_clearance_and_bioavailability_/24601556

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.g005
https://figshare.com/articles/figure/Plot_of_maturation_of_clearance_and_bioavailability_/24601556

المؤلفون: Lufina Tsirizani Galileya, Roeland E. Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F. Cotton, Helen McIlleron, Paolo Denti

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Cancer, Science Policy, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, optimize tuberculosis dosing, identifying factors altering, human immunodeficiency virus, 1 %, drug &# 8211, suboptimal drug exposures, used nonlinear mixed, pediatric pharmacokinetic studies, line tuberculosis drugs, large pharmacokinetic studies, hiv per se, gov registration numbers, 0 %, around 3 months, age also affected, lower rifampicin exposures, pharmacokinetic results

Time: 78, 61

Relation: https://figshare.com/articles/dataset/Characteristics_of_studies_included_in_the_pooled_analysis_/24601559

الاتاحة: https://doi.org/10.1371/journal.pmed.1004303.t001
https://figshare.com/articles/dataset/Characteristics_of_studies_included_in_the_pooled_analysis_/24601559

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/figure/_sup_15_sup_N_sup_13_sup_C_sub_co_sub_sup_18_sup_O_sup_13_sup_C_sub_en_sub_isotopic_variations_among_age_ranges_of_infants_children_from_Bacuranao_I_/19109087

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.g004

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/figure/Transverse_comparison_of_sup_15_sup_N_Air_values_by_infants_children_age_calculated_from_reconstructed_maximum_density_estimators_MDEs_Tsutaya_and_Yoneda_2013_/19109084

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.g003

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/figure/Transverse_comparison_of_enamel_oxygen_stable_isotope_values_sup_18_sup_O_by_age_at_tissue_formation_of_the_Bacuranao_I_individuals_/19109090

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.g005

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/figure/Location_of_the_archaeological_site_of_Bacuranao_I_Mayabeque_Cuba_/19109081

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.g002

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/figure/Rib_collagen_nitrogen_sup_15_sup_N_and_tooth_enamel_oxygen_sup_18_sup_O_stable_isotope_composition_formed_at_similar_ages_in_infants_and_children_from_Bacuranao_I_Mayabeque_Cuba_/19109096

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.g007

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/figure/Variations_in_sup_18_sup_O_and_sup_13_sup_C_sub_en_sub_among_dental_tissues_of_infants_children_at_Bacuranao_I_Mayabeque_Cuba_/19109093

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.g006

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/figure/Stable_isotopes_during_the_different_stages_of_the_weaning_process_/19109078

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.g001

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/dataset/Nitrogen_sup_15_sup_N_and_carbon_sup_13_sup_C_sub_co_sub_stable_isotope_values_of_Bacuranao_I_infants_and_children_/19109105

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.t002

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/dataset/General_information_of_the_Bacuranao_I_Mayabeque_Cuba_individuals_included_in_this_study_/19109102

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.t001

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/figure/Nitrogen_sup_15_sup_N_and_carbon_sup_13_sup_C_sub_co_sub_sup_13_sup_C_sub_en_sub_stable_isotope_composition_of_tissues_formed_at_similar_ages_in_infants_and_children_from_Bacuranao_I_Mayabeque_Cuba_/19109099

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.g008

المؤلفون: Yadira Chinique de Armas (3990734), Anna-Maria Mavridou (12035000), Jorge Garcell Domínguez (12035003), Kaitlyn Hanson (12035006), Jason Laffoon (12035009)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, rib collagen samples, first six months, around 3 months, tested whether changes, multiple isotope systems, 18 , 15 , 13 , warn model suggested, oxygen stable isotopes, ended around 1, div >< p, weaning process started, n showed enrichment, stable isotopes, weaning process, warn ), multiple non, detect changes

Relation: https://figshare.com/articles/dataset/Oxygen_and_Carbon_enamel_values_of_individuals_from_Bacuranao_I_Mayabeque_Cuba_/19109108

الاتاحة: https://doi.org/10.1371/journal.pone.0262435.t003