المؤلفون: Román-Álamo, Lucía, Avalos-Padilla, Yunuen, Bouzón-Arnáiz, Inés, Iglesias, Valentin, Fernández Lajo, Jorge, Monteiro, Juan M., Rivas, Luis, Fisa, Roser, Riera, Cristina, Andreu Martínez, David, Pintado-Grima, Carlos, Ventura, Salvador, Arce, Elsa M., Muñoz-Torrero, Diego, Fernàndez Busquets, Xavier

مصطلحات موضوعية: Leishmania, YAT2150, Antileishmanial drugs, Protein aggregation

وصف الملف: application/pdf

Relation: Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0112723; info:eu-repo/grantAgreement/ES/2PE/CEX2018-000806-S; info:eu-repo/grantAgreement/ES/3PE/PID2021-128325OB-I00; info:eu-repo/grantAgreement/ES/2PE/PID2020-118127RB-I00; info:eu-repo/grantAgreement/ES/2PE/AGL2017-84097-C2-2-R; http://hdl.handle.net/10230/59805

الاتاحة: http://hdl.handle.net/10230/59805
https://doi.org/10.1128/aac.01127-23

المؤلفون: Roseboom, Ignace C, Rosing, Hilde, Beijnen, Jos H, Dorlo, Thomas P. C., PhD, 1983

المصدر: BMC Biomedical chromotography. 37(7)

مصطلحات موضوعية: antileishmanial drugs, bioanalysis, chromatography, leishmaniasis, pharmacokinetic studies

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-493793
https://doi.org/10.1002/bmc.5519
https://uu.diva-portal.org/smash/get/diva2:1726467/FULLTEXT01.pdf

المؤلفون: Prof. Fernanda Andreia Rosa, Samara Mendes de Souza Melo, Dr. Karlos Eduardo Pianoski, Julia Poletto, Mariellen Guilherme dosSantos, Dr. Michael Jackson Vieira da Silva, Dr. Danielle Lazarin‐Bidóia, Dr. Hélito Volpato, Prof. Sidnei Moura, Prof. Celso Vataru Nakamura

المصدر: ChemistryOpen, Vol 10, Iss 10, Pp 931-938 (2021)

مصطلحات موضوعية: antileishmanial drugs, antiprotozoal agents, cyclocondensation reactions, isoxazoles, N-acylhydrazone derivatives, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2191-1363

URL الوصول: https://doaj.org/article/239afcbf39dd485eb5b702be69eab4d1

المؤلفون: Marta Monteiro, Sara Prata, Luís Cardoso, Isabel Pereira da Fonseca, Rodolfo Oliveira Leal

المصدر: Parasites & Vectors, Vol 14, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Antileishmanial drugs, Canine leishmaniosis, Prevention, Questionnaire-based survey, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-3305

URL الوصول: https://doaj.org/article/c3d7219cfa2142a59dcce01168c8e53f

المؤلفون: Ana Victoria Ibarra-Meneses, Audrey Corbeil, Victoria Wagner, Francis Beaudry, Rubens L. do Monte-Neto, Christopher Fernandez-Prada

المصدر: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

مصطلحات موضوعية: Leishmania, antileishmanial drugs, mode of action, thermal proteome profiling, drug resistance, antimony, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2022.954144/full; https://doaj.org/toc/2235-2988

URL الوصول: https://doaj.org/article/fc8fe37f8be44d71943c8f1a1d4c7be3

المؤلفون: Tatiana Barbosa dos Santos Magalhães, Dahara Keyse Carvalho Silva, Jessica da Silva Teixeira, Juliana Dizaira Teles De Lima, José Maria Barbosa-Filho, Diogo Rodrigo Magalhães Moreira, Elisalva Teixeira Guimarães, Milena Botelho Pereira Soares

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: leishmaniasis, betulinic acid, antileishmanial drugs, mechanism action, L. amazonensis, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.846123/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/d99d8627ed16465aa773021fcc41ce8e

المؤلفون: Robledo, S.M. (Sara), Murillo, J. (Javier), Arbeláez, N. (Natalia), Montoya, A. (Andrés), Ospina, V. (Victoria), Jürgens, F.M. (Franziska), Vélez, I.D. (Iván), Schmidt, T.J. (Thomas)

المساهمون: Universitäts- und Landesbibliothek Münster

مصطلحات موضوعية: Arnica montana L., Arnica tincture, natural products, sesquiterpene lactones, cutaneous leishmaniasis, antileishmanial drugs, Leishmania braziliensis, Leishmania tropica, Mesocricetus auratus, ddc:615, info:eu-repo/classification/ddc/615, Pharmacology and therapeutics

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/reference/url/https://www.mdpi.com/article/10.3390/ph15070776/s1

الاتاحة: https://nbn-resolving.org/urn:nbn:de:hbz:6-93029492994
https://doi.org/10.17879/93029494903
https://miami.uni-muenster.de/Record/1721c605-9b37-4b1b-ba29-141b6623931a
https://repositorium.uni-muenster.de/transfer/miami/1721c605-9b37-4b1b-ba29-141b6623931a

المؤلفون: Sara M. Robledo, Javier Murillo, Natalia Arbeláez, Andrés Montoya, Victoria Ospina, Franziska M. Jürgens, Iván D. Vélez, Thomas J. Schmidt

المصدر: Pharmaceuticals; Volume 15; Issue 7; Pages: 776

مصطلحات موضوعية: Arnica montana L., Arnica tincture, natural products, sesquiterpene lactones, cutaneous leishmaniasis, antileishmanial drugs, Leishmania braziliensis, Leishmania tropica, Mesocricetus auratus

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/ph15070776

الاتاحة: https://doi.org/10.3390/ph15070776

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/figure/Heat_map_representation_row_Z-score_of_the_general_thermal_stability_of_i_Li_i_FS-B_soluble_protein_cell_extracts_/25320348

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.g005
https://figshare.com/articles/figure/Heat_map_representation_row_Z-score_of_the_general_thermal_stability_of_i_Li_i_FS-B_soluble_protein_cell_extracts_/25320348

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/figure/Phenotypic_characterization_of_i_L_i_i_infantum_i_WT_reference_strain_and_i_Li_i_FS-A_and_i_Li_i_FS-B_clinical_isolates_after_pre-exposure_to_Sb_and_MTX_/25320342

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.g003
https://figshare.com/articles/figure/Phenotypic_characterization_of_i_L_i_i_infantum_i_WT_reference_strain_and_i_Li_i_FS-A_and_i_Li_i_FS-B_clinical_isolates_after_pre-exposure_to_Sb_and_MTX_/25320342

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/dataset/Proteomic_data_generated_in_this_study_/25320333

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.s002
https://figshare.com/articles/dataset/Proteomic_data_generated_in_this_study_/25320333

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/figure/Normalized_mRNA_expression_levels_of_i_mrpA_i_i_ptr1_i_and_i_dhfr_i_in_non-exposed_parasites_/25320339

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.g002
https://figshare.com/articles/figure/Normalized_mRNA_expression_levels_of_i_mrpA_i_i_ptr1_i_and_i_dhfr_i_in_non-exposed_parasites_/25320339

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/dataset/Summary_of_proteins_identified_in_Sb-treated_and_MTX-treated_i_Li_i_FS-A_demonstrating_a_positive_temperature_shift_/25320354

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.t002
https://figshare.com/articles/dataset/Summary_of_proteins_identified_in_Sb-treated_and_MTX-treated_i_Li_i_FS-A_demonstrating_a_positive_temperature_shift_/25320354

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/figure/Heat_map_representation_row_Z-score_of_the_general_thermal_stability_of_i_Li_i_FS-A_soluble_protein_cell_extracts_/25320345

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.g004
https://figshare.com/articles/figure/Heat_map_representation_row_Z-score_of_the_general_thermal_stability_of_i_Li_i_FS-A_soluble_protein_cell_extracts_/25320345

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/figure/Evaluation_of_ROS_accumulation_and_parasite_survival_in_the_absence_and_the_presence_of_Sb_and_MTX_/25320336

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.g001
https://figshare.com/articles/figure/Evaluation_of_ROS_accumulation_and_parasite_survival_in_the_absence_and_the_presence_of_Sb_and_MTX_/25320336

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/figure/Normalized_mRNA_expression_levels_of_i_mrpA_i_i_ptr1_i_and_i_ass_i_in_i_Li_i_TW_non-exposed_-_and_pre-exposed_to_MTX_EC_sub_90_sub_/25320330

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.s001
https://figshare.com/articles/figure/Normalized_mRNA_expression_levels_of_i_mrpA_i_i_ptr1_i_and_i_ass_i_in_i_Li_i_TW_non-exposed_-_and_pre-exposed_to_MTX_EC_sub_90_sub_/25320330

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/dataset/EC_sub_50_sub_values_for_methotrexate_and_antimony_in_i_Leishmania_i_promastigotes_and_amastigotes_calculated_from_concentration-response_curves_/25320351

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.t001
https://figshare.com/articles/dataset/EC_sub_50_sub_values_for_methotrexate_and_antimony_in_i_Leishmania_i_promastigotes_and_amastigotes_calculated_from_concentration-response_curves_/25320351

المؤلفون: Lorena Bernardo, Ana Victoria Ibarra-Meneses, Noelie Douanne, Audrey Corbeil, Jose Carlos Solana, Francis Beaudry, Eugenia Carrillo, Javier Moreno, Christopher Fernandez-Prada

مصطلحات موضوعية: Medicine, Pharmacology, Evolutionary Biology, Ecology, Immunology, Cancer, Infectious Diseases, Virology, reactive oxygen species, displaying high levels, depressed immune system, alarmingly growing levels, ones receiving methotrexate, clinical strains (<, effective treatment coupled, reference strain (<, dog later relapsing, undermine antileishmanial treatment, refusing antileishmanial drugs, leishmania infantum <, treated vl dogs, leishmania <, infantum <, antileishmanial drugs, methotrexate cross, circulating strains, li <, l <, wide range, results show

Relation: https://figshare.com/articles/dataset/Summary_of_proteins_identified_in_Sb-treated_and_MTX-treated_i_Li_i_FS-B_demonstrating_a_positive_temperature_shift_/25320357

الاتاحة: https://doi.org/10.1371/journal.pntd.0012015.t003
https://figshare.com/articles/dataset/Summary_of_proteins_identified_in_Sb-treated_and_MTX-treated_i_Li_i_FS-B_demonstrating_a_positive_temperature_shift_/25320357

المؤلفون: Marta Monteiro (2802382), Sara Prata (10937250), Luís Cardoso (449497), Isabel Pereira da Fonseca (169927), Rodolfo Oliveira Leal (10937253)

مصطلحات موضوعية: Medicine, Biotechnology, Ecology, Sociology, Cancer, Infectious Diseases, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Antileishmanial drugs, Canine leishmaniosis, Prevention, Questionnaire-based survey

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Diagnosis_and_clinical_management_of_canine_leishmaniosis_by_general_veterinary_practitioners_a_questionnaire-based_survey_in_Portugal/14746314

الاتاحة: https://doi.org/10.6084/m9.figshare.14746314.v1

المؤلفون: Bárbara Domínguez-Asenjo (10331517), Camino Gutiérrez-Corbo (10331520), María Álvarez-Bardón (10959543), Yolanda Pérez-Pertejo (10331523), Rafael Balaña-Fouce (10331526), Rosa M. Reguera (9751154)

مصطلحات موضوعية: Medicine, Pharmacology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Physical Sciences not elsewhere classified, L . major, hit, vivo models, cutaneous leishmaniasis, vivo mouse splenocytes, Cutaneous Leishmaniasis Leishmaniases, mouse splenic explants, Ex Vivo Phenotypic Screening, Potential New Treatment, 1769 compounds, L . donovani, Leishmania infantum strain, Small Repurposing Drug Collections ., antileishmanial drugs

Relation: https://figshare.com/articles/journal_contribution/Ex_Vivo_Phenotypic_Screening_of_Two_Small_Repurposing_Drug_Collections_Identifies_Nifuratel_as_a_Potential_New_Treatment_against_Visceral_and_Cutaneous_Leishmaniasis/14770218

الاتاحة: https://doi.org/10.1021/acsinfecdis.1c00139.s001