المؤلفون: Queda, Fausto, Calò, Sonia, Gwizdala, Karolina, Magalhães, João D., Cardoso, Sandra M., Chaves, Sílvia, Piemontese, Luca, Santos, M. Amélia

مصطلحات موضوعية: arylsulfonamide, donepezil, anti-neurodegeneratives, Alzheimer´s disease, AChE inhibitors, Aβ aggregation, Acetylcholinesterase, Alzheimer Disease, Amyloid beta-Peptides, Cell Line, Tumor, Cholinesterase Inhibitors, Humans, Ligands, Piperazines, Piperidines, Structure-Activity Relationship, Sulfonamides

Relation: #PLACEHOLDER_PARENT_METADATA_VALUE#; UID/QUI/00100/2013; UID/QUI/00100/ 2019; POCI-01-0145-FEDER-030712; CENTRO-01-0145-FEDER-000012; http://hdl.handle.net/10316/105262

الاتاحة: http://hdl.handle.net/10316/105262
https://doi.org/10.3390/molecules26061658

المؤلفون: Chaves, Sílvia, Resta, Simonetta, Rinaldo, Federica, Costa, Marina, Josselin, Romane, Gwizdala, Karolina, Piemontese, Luca, Capriati, Vito, Santos, A. Raquel Pereira, Cardoso, Sandra M., Santos, M. Amélia

مصطلحات موضوعية: hydroxyphenyl-benzimidazole, donepezil, anti-neurodegeneratives, Alzheimer´s disease, multifunctional drugs, metal chelation, Acetylcholinesterase, Alzheimer Disease, Amyloid beta-Peptides, Antioxidants, Chelating Agents, Cholinesterase Inhibitors, Humans, Indazoles, Ligands, Molecular Docking Simulation, Molecular Structure, Piperazine, Piperidines, Structure-Activity Relationship

Relation: https://hdl.handle.net/10316/106464

الاتاحة: https://hdl.handle.net/10316/106464
https://doi.org/10.3390/molecules25040985

المؤلفون: Sandra M. Cardoso, M. Amélia Santos, Fausto Queda, Sonia Calò, Sílvia Chaves, Luca Piemontese, Karolina Gwizdala, João D. Magalhães

المصدر: Molecules
Volume 26
Issue 6
Molecules, Vol 26, Iss 1658, p 1658 (2021)

مصطلحات موضوعية: Drug, Aβ aggregation, Alzheimer´s disease, media_common.quotation_subject, Pharmaceutical Science, Pharmacology, AChE inhibitors, Ligands, Article, Piperazines, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, lcsh:Organic chemistry, Piperidines, Alzheimer Disease, Cell Line, Tumor, Drug Discovery, medicine, Humans, Physical and Theoretical Chemistry, arylsulfonamide, Donepezil, IC50, 030304 developmental biology, media_common, 0303 health sciences, Sulfonamides, Amyloid beta-Peptides, Chemistry, Drug discovery, Organic Chemistry, Biological activity, Acetylcholinesterase, donepezil, Chemistry (miscellaneous), Molecular Medicine, anti-neurodegeneratives, Cholinesterase Inhibitors, Pharmacophore, Lead compound, 030217 neurology & neurosurgery, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27c64ffc7590e3ff302a2328c2e11fe
http://europepmc.org/articles/PMC8002323

المؤلفون: Keri, Rangappa S., Quintanova, Catarina, Marques, Sérgio M., Esteves, A. Raquel, Cardoso, Sandra M., Santos, M. Amélia

مصطلحات موضوعية: Tacrine, Benzothiazole, Alzheimer’s disease, Acetylcholinesterase inhibitors, Anti-Aβ aggregation, Anti-neurodegeneratives

Relation: http://www.sciencedirect.com/science/article/pii/S0968089613004641; Keri, Rangappa S. [et. al] - Design, synthesis and neuroprotective evaluation of novel tacrine–benzothiazole hybrids as multi-targeted compounds against Alzheimer’s disease. "Bioorganic & Medicinal Chemistry". ISSN 0968-0896. Vol. 21 Nº.15 (2013) p. 4559-4569; http://hdl.handle.net/10316/27327

الاتاحة: http://hdl.handle.net/10316/27327
https://doi.org/10.1016/j.bmc.2013.05.028

المؤلفون: M. Amélia Santos, Karolina Gwizdala, Federica Rinaldo, Sílvia Chaves, Vito Capriati, Marina Costa, A. Raquel Pereira-Santos, Romane Josselin, Sandra M. Cardoso, Simonetta Resta, Luca Piemontese

المصدر: Molecules, Vol 25, Iss 4, p 985 (2020)
Molecules
Volume 25
Issue 4

مصطلحات موضوعية: Denticity, Pharmaceutical Science, Ligands, hydroxyphenyl-benzimidazole, 01 natural sciences, Antioxidants, Analytical Chemistry, chemistry.chemical_compound, multifunctional drugs, Piperidines, Drug Discovery, Moiety, Donepezil, Chelating Agents, Molecular Structure, Biological activity, hemic and immune systems, Acetylcholinesterase, 3. Good health, donepezil, Molecular Docking Simulation, Chemistry (miscellaneous), Molecular Medicine, alzheimer´s disease, medicine.drug, Indazoles, chemical and pharmacologic phenomena, 010402 general chemistry, Article, lcsh:QD241-441, Structure-Activity Relationship, lcsh:Organic chemistry, Alzheimer Disease, medicine, Humans, Chelation, Physical and Theoretical Chemistry, Piperazine, Amyloid beta-Peptides, 010405 organic chemistry, organic chemicals, Organic Chemistry, Combinatorial chemistry, 0104 chemical sciences, chemistry, metal chelation, Nitro, anti-neurodegeneratives, Cholinesterase Inhibitors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e01e0194479869baa90bad387fe4f5
https://www.mdpi.com/1420-3049/25/4/985

المؤلفون: Chaves, Sílvia, PIEMONTESE, LUCA, Hiremathad, Asha, Santos, Maria Amélia

المساهمون: Chaves, Sílvia, Piemontese, Luca, Hiremathad, Asha, Santos, Maria Amélia

مصطلحات موضوعية: Hydroxypyridinones, 3-hydroxy-4-pyridinones, iron chelators, anti-neurodegeneratives, bioinorganic medicinal chemistry

Relation: info:eu-repo/semantics/altIdentifier/pmid/28359230; info:eu-repo/semantics/altIdentifier/wos/WOS:000422944100009; volume:25; issue:1; firstpage:97; lastpage:112; numberofpages:16; journal:CURRENT MEDICINAL CHEMISTRY; http://hdl.handle.net/11586/183704; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85040811746

الاتاحة: http://hdl.handle.net/11586/183704
https://doi.org/10.2174/0929867324666170330092304

المؤلفون: Šebestík, J. (Jaroslav), Marques, S. M., Falé, P. L., Santos, S., Arduíno, D. M., Cardoso, S. M., Oliveira, S. M., Serralheiro, M. L. M., Santos, A. M.

مصطلحات موضوعية: acetylcholinesterase inhibitors, antioxidants, hybrid ligands, anti-neurodegeneratives, Alzheimer´s disease

Relation: urn:pissn: 1475-6366; urn:eissn: 1475-6374; http://hdl.handle.net/11104/0198445

الاتاحة: https://doi.org/10.3109/14756366.2010.529806
http://hdl.handle.net/11104/0198445

المؤلفون: Megalizzi, Véronique

المساهمون: Decaestecker, Christine, Kauffmann, Jean-Michel, Van Damme, Marc, Salmon, Isabelle, Maurice, Tangui, Fontaine, Véronique, Dehaye, Jean-Paul

مصطلحات موضوعية: Sciences pharmaceutiques, Gliomas, Drug resistance in cancer cells, Cancer -- Chemotherapy, Chemotherapy, Gliome, Cellules cancéreuses -- Résistance aux médicaments, Cancer -- Chimiothérapie, Chimiothérapie, sigma receptor, chemioresistance/récepteur sigma, cancer, endoplasmic reticulum stress, lipid synthesis, anti- neurodegenerative and anti-psychotic drugs, le cancer, la synthèse des lipides, le stress du réticulum endoplasmique, drogues anti-neurodégénératives et anti-psychotiqu, chimioresistance

وصف الملف: 3 full-text file(s): application/pdf | application/pdf | application/pdf

Relation: local/bictel.ulb.ac.be:ULBetd-07042011-121707; local/ulbcat.ulb.ac.be:920586; https://dipot.ulb.ac.be/dspace/bitstream/2013/209906/1/21257566-ae4f-4faf-8d77-fa92672d0f92.txt; https://dipot.ulb.ac.be/dspace/bitstream/2013/209906/2/119b0a88-64be-42d3-ac61-321db495678c.txt; https://dipot.ulb.ac.be/dspace/bitstream/2013/209906/3/a7d7118b-7749-4937-8513-5019e91f731b.txt; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209906

الاتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209906
https://dipot.ulb.ac.be/dspace/bitstream/2013/209906/1/21257566-ae4f-4faf-8d77-fa92672d0f92.txt
https://dipot.ulb.ac.be/dspace/bitstream/2013/209906/2/119b0a88-64be-42d3-ac61-321db495678c.txt
https://dipot.ulb.ac.be/dspace/bitstream/2013/209906/3/a7d7118b-7749-4937-8513-5019e91f731b.txt