المؤلفون: Sebastian Jäger, Doreen Könning, Nicolas Rasche, Felix Hart, Janike Sensbach, Carina Krug, Sabine Raab-Westphal, Konstantin Richter, Carlo Unverzagt, Stefan Hecht, Jan Anderl, Christian Schröter

مصطلحات موضوعية: Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Mental Health, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, presented results emphasize, crucial design feature, antitumor activity could, analogous cathepsin b, several tumor types, established adc linkers, nonmalignant cells compared, cleavable duocarmycin adc, adc linker cleavage, nonmalignant cells, tumor selectivity, exatecan adc, adc pharmacokinetics, adc development, linkers must, iduronide linkers, vivo <, therapeutic success, target cell, subnanomolar range

Relation: https://figshare.com/articles/journal_contribution/Generation_and_Characterization_of_Iduronidase-Cleavable_ADCs/24756141

الاتاحة: https://doi.org/10.1021/acs.bioconjchem.3c00363.s001
https://figshare.com/articles/journal_contribution/Generation_and_Characterization_of_Iduronidase-Cleavable_ADCs/24756141