المؤلفون: McKenzie, Cathryn, Bucks, Romola S, Weinborn, Michael, Bourgeat, Pierrick, Salvado, Olivier, Gavett, Brandon E

مصطلحات موضوعية: Biological Psychology, Psychology, Neurodegenerative, Dementia, Behavioral and Social Science, Alzheimer's Disease, Aging, Neurosciences, Brain Disorders, Acquired Cognitive Impairment, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Basic Behavioral and Social Science, Neurological, cognitive reserve, Alzheimer's disease, amyloid cascade hypothesis, executive function, AT(N) classification system, cognitive resilience, FDG metabolism, Alzheimer’s disease, Biochemistry and Cell Biology, Cognitive Sciences, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2xx4z4wt
https://escholarship.org/content/qt2xx4z4wt/qt2xx4z4wt.pdf

المؤلفون: Vladimir Volloch, Sophia Rits-Volloch

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 11, p 6036 (2024)

مصطلحات موضوعية: Conventional and unconventional Alzheimer’s disease, Alzheimer’s disease-like dementia (ADLD) and Alzheimer’s disease-related dementia (ADRD), Neuronal integrated stress response (ISR), Intraneuronal Aβ ( i Aβ) and AβPP-independent generation of i Aβ, Amyloid cascade hypothesis 2.0 (ACH2.0) and expanded amyloid cascade hypothesis 2.0 (ACH2.0/E), Therapeutic strategies for conventional and unconventional Alzheimer’s disease and for aging-associated cognitive decline, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/11/6036; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/ad2cecff4aff4fdd8ae417232ae41e90

الاتاحة: https://doi.org/10.3390/ijms25116036
https://doaj.org/article/ad2cecff4aff4fdd8ae417232ae41e90

المؤلفون: Vladimir Volloch, Sophia Rits-Volloch

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 18, p 9913 (2024)

مصطلحات موضوعية: conventional and unconventional Alzheimer’s disease, neuronal integrated stress response (ISR), intraneuronal Aβ ( i Aβ), AβPP-independent generation of i Aβ, amyloid cascade hypothesis 2.0 (ACH2.0), therapeutic strategies for conventional and unconventional Alzheimer’s disease, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/18/9913; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/1b2774238f324c59a72f9fd0dc09e334

الاتاحة: https://doi.org/10.3390/ijms25189913
https://doaj.org/article/1b2774238f324c59a72f9fd0dc09e334

المؤلفون: Vicente Zurdo, David, Gómez Mejía, Esther, Rosales Conrado, Noelia, León González, María Eugenia De

مصطلحات موضوعية: Polyphenols, Alzheimer’s disease, Analytical chemistry, Amyloid cascade hypothesis, Polyphenols extraction, Polyphenols characterization, Bioanalytical methods, In vitro assays, In vivo assays, Chemometrics, Ciencias, 23 Química

Time: 54

وصف الملف: application/pdf

Relation: Spanish Ministry of Science, Innovation and Universities (PID2020-114714RB-I00); Vicente-Zurdo, D., Gómez-Mejía, E., Rosales-Conrado, N., & León-González, M. E. (2024). A Comprehensive Analytical Review of Polyphenols: Evaluating Neuroprotection in Alzheimer’s Disease. International Journal of Molecular Sciences, 25(11), 5906.; https://hdl.handle.net/20.500.14352/105667

الاتاحة: https://hdl.handle.net/20.500.14352/105667
https://doi.org/10.3390/ijms25115906

المؤلفون: Vladimir Volloch, Sophia Rits-Volloch

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 5, p 2981 (2024)

مصطلحات موضوعية: Alzheimer’s disease (AD), conventional AD, unconventional AD, amyloid cascade hypothesis (ACH), ACH-based models of AD, ACH-based AD drugs, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/5/2981; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/2961926ff5c045b5b86b9acd5f5490b6

الاتاحة: https://doi.org/10.3390/ijms25052981
https://doaj.org/article/2961926ff5c045b5b86b9acd5f5490b6

المؤلفون: Kepp, Kasper P, Robakis, Nikolaos K, Høilund-Carlsen, Poul F, Sensi, Stefano L, Vissel, Bryce

المصدر: Kepp , K P , Robakis , N K , Høilund-Carlsen , P F , Sensi , S L & Vissel , B 2023 , ' The amyloid cascade hypothesis : an updated critical review ' , Brain , vol. 146 , no. 10 , pp. 3969-3990 . https://doi.org/10.1093/brain/awad159

مصطلحات موضوعية: Alzheimer’s disease, aducanumab, amyloid cascade hypothesis, lecanemab, β-amyloid, Humans, Amyloid beta-Peptides, Antibodies, Amyloid, Cognition, Alzheimer Disease/pathology

وصف الملف: application/pdf

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/3f1ba459-0d07-48b3-bdd0-a1bd4bf1aebb
https://doi.org/10.1093/brain/awad159
https://findresearcher.sdu.dk/ws/files/266299003/Amyloid_Review_BRAIN_acceptedversion.pdf

المؤلفون: Vladimir Volloch, Sophia Rits-Volloch

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 15; Pages: 12246

مصطلحات موضوعية: the amyloid cascade hypothesis 2.0 (ACH2.0), intraneuronal Aβ ( i Aβ), Aβ protein precursor (AβPP)-independent generation of i Aβ, aging-related cognitive dysfunction (AACD), i Aβ depletion therapy for AD and AACD, BACE1 and BACE2 activators as AD and AACD drugs

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms241512246

الاتاحة: https://doi.org/10.3390/ijms241512246

المؤلفون: Florence Haut, Elentina K. Argyrousi, Ottavio Arancio

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 1, p 259 (2023)

مصطلحات موضوعية: amyloid-beta, Tau, amyloid-precursor protein, amyloid cascade hypothesis, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/1/259; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/93a443ec97254c9fa166190c0653ea08

الاتاحة: https://doi.org/10.3390/ijms25010259
https://doaj.org/article/93a443ec97254c9fa166190c0653ea08

المؤلفون: Vladimir Volloch, Sophia Rits-Volloch

المصدر: International Journal of Molecular Sciences, Vol 24, Iss 24, p 17586 (2023)

مصطلحات موضوعية: Alzheimer’s disease (AD), Aging-Associated Cognitive Decline (AACD), Amyloid Cascade Hypothesis 2.0 (ACH2.0), intraneuronal Aβ ( i Aβ), Aβ protein precursor (AβPP), AβPP-independent i Aβ production pathway, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/24/24/17586; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/4c23a644d5a748859780963077550658

الاتاحة: https://doi.org/10.3390/ijms242417586
https://doaj.org/article/4c23a644d5a748859780963077550658

المؤلفون: Ernesto Fedele

المصدر: International Journal of Molecular Sciences, Vol 24, Iss 14499, p 14499 (2023)

مصطلحات موضوعية: Alzheimer’s disease, Aβ antibodies, amyloid cascade hypothesis, clinical trials, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/24/19/14499; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/55736c9a5a7543239ff2c185c1e3da90

الاتاحة: https://doi.org/10.3390/ijms241914499
https://doaj.org/article/55736c9a5a7543239ff2c185c1e3da90

المؤلفون: Cathryn McKenzie, Romola S. Bucks, Michael Weinborn, Pierrick Bourgeat, Olivier Salvado, Brandon E. Gavett

المصدر: Frontiers in Aging Neuroscience, Vol 14 (2022)

مصطلحات موضوعية: cognitive reserve, Alzheimer’s disease, amyloid cascade hypothesis, executive function, AT(N) classification system, cognitive resilience, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2022.943823/full; https://doaj.org/toc/1663-4365

URL الوصول: https://doaj.org/article/7ceeb8afa3ac471db7cdf26859ff1949

المؤلفون: Firas H. Bazzari, Amjad H. Bazzari

المصدر: Molecules; Volume 27; Issue 24; Pages: 8823

مصطلحات موضوعية: Alzheimer’s disease, BACE1, amyloid cascade hypothesis, small molecules, clinical trials, AD pathophysiology, risk factors

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules27248823

الاتاحة: https://doi.org/10.3390/molecules27248823

المؤلفون: Beckett, Laurel A, Donohue, Michael C, Wang, Cathy, Aisen, Paul, Harvey, Danielle J, Saito, Naomi, Initiative, Alzheimer's Disease Neuroimaging

المصدر: Alzheimer's & Dementia. 11(7)

مصطلحات موضوعية: Cognitive and Computational Psychology, Psychology, Biomedical Imaging, Dementia, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurodegenerative, Clinical Research, Brain Disorders, Acquired Cognitive Impairment, Behavioral and Social Science, Alzheimer's Disease, Neurosciences, Aging, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, 4.1 Discovery and preclinical testing of markers and technologies, Neurological, Age Factors, Alzheimer Disease, Amyloid, Brain, Cognitive Dysfunction, Disease Progression, Humans, Longitudinal Studies, Memory Disorders, Mental Status Schedule, Multicenter Studies as Topic, Neuroimaging, Alzheimer's disease, Subjective memory complaints, Amyloid cascade hypothesis, Alzheimer's Disease Neuroimaging Initiative, Clinical Sciences, Geriatrics, Clinical sciences, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4mj5494v
https://escholarship.org/content/qt4mj5494v/qt4mj5494v.pdf

المؤلفون: Capurro, Valeria, Busquet, Perrine, Lopes, Joao Pedro, Bertorelli, Rosalia, Tarozzo, Glauco, Bolognesi, Maria Laura, Piomelli, Daniele, Reggiani, Angelo, Cavalli, Andrea, Sensi, Stefano L

المصدر: PLoS ONE. 8(2)

مصطلحات موضوعية: Amyloid Cascade Hypothesis, Target-Directed Ligands, Morris Water Maze, Object Recognition, Passive-Avoidance, Memory Impairment, Mouse Model, Mice, Beta, Accumulation

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/50q255c7

المؤلفون: Youki Masuda (10941210), Koji Fujihara (10941213), Satoshi Hayashi (2015587), Hiroaki Sasaki (775040), Yoshihiro Kino (259163), Hitoshi Kamauchi (5158736), Masahiro Noji (1632997), Jun-ichi Satoh (20112), Toshikatsu Takanami (2015590), Kaoru Kinoshita (1562020), Kiyotaka Koyama (1562017)

مصطلحات موضوعية: Biochemistry, Neuroscience, Pharmacology, Cancer, Hematology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, BACE, 50.3 μ M, amyloid cascade hypothesis, assay, albatrelactone, compound, acid, Th-T, IC 50 values, UV, MS, ECD, β aggregation, 2 D NMR spectroscopy, 1.4 μ M, Mushroom Albatrellus yasudae, methyl, ester, AD, IR

Relation: https://figshare.com/articles/journal_contribution/Inhibition_of_BACE1_and_Amyloid_Aggregation_by_Meroterpenoids_from_the_Mushroom_i_Albatrellus_yasudae_i_/14748948

الاتاحة: https://doi.org/10.1021/acs.jnatprod.0c01329.s001

المؤلفون: Tsuyoshi Nakai, Kiyofumi Yamada, Hiroyuki Mizoguchi

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 11; Pages: 5549

مصطلحات موضوعية: Alzheimer’s disease, amyloid cascade hypothesis, tau, neurofibrillary tangles, biomarkers, animal models, pharmacological intervention

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biology; https://dx.doi.org/10.3390/ijms22115549

الاتاحة: https://doi.org/10.3390/ijms22115549

المؤلفون: Gwendolyn E. Kaeser, Jerold Chun

المصدر: Frontiers in Genetics, Vol 11 (2020)

مصطلحات موضوعية: Alzheimer’s disease, mosaicism, somatic gene recombination, amyloid cascade hypothesis, gencDNA, amyloid precursor protein, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2020.00390/full; https://doaj.org/toc/1664-8021

URL الوصول: https://doaj.org/article/b36ccb00aff840d1a4b9ddd06eaead53

المؤلفون: Davies, G, Gorman, R, Milne, R

المساهمون: Jenkins, N, Jack-Waugh, A, Ritchie, L

مصطلحات موضوعية: dementia, amyloid cascade hypothesis, genetically modified mice, drug development, patient involvement, fabrication

Relation: https://policy.bristoluniversitypress.co.uk/multi-species-dementia-studies; 205393/Z/16/Z; 220540/Z/20/A; http://hdl.handle.net/10871/133588

الاتاحة: http://hdl.handle.net/10871/133588

المؤلفون: STANCU, Ilie Cosmin, Vasconcelos, Bruno, TERWEL, Dick, DEWACHTER, Ilse

المصدر: Review

مصطلحات موضوعية: Amyloid, Tau, Alzheimer's disease, Animal models, Amyloid cascade hypothesis, Synaptic dysfunction, Inflammation, Prion

وصف الملف: application/pdf

Relation: Molecular neurodegeneration, 9 (1) (Art N° ARTN 51); http://hdl.handle.net/1942/30303; 000345934700001

الاتاحة: http://hdl.handle.net/1942/30303
https://doi.org/10.1186/1750-1326-9-51

المؤلفون: Daly, Timothy, Houot, Marion, Barberousse, Anouk, Agid, Yves, Epelbaum, Stéphane

المساهمون: Sorbonne Université - Faculté des Lettres - UFR de Philosophie (SU UFR Philo), Sorbonne Université - Faculté des Lettres (SU FdL), Sorbonne Université (SU)-Sorbonne Université (SU), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Algorithms, models and methods for images and signals of the human brain = Algorithmes, modèles et méthodes pour les images et les signaux du cerveau humain ICM Paris (ARAMIS), Inria de Paris, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière AP-HP, CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)

المصدر: ISSN: 1387-2877 ; Journal of Alzheimer's Disease ; https://hal.sorbonne-universite.fr/hal-02989156 ; Journal of Alzheimer's Disease, 2020, 74 (4), pp.1309-1317. ⟨10.3233/JAD-191321⟩.

مصطلحات موضوعية: Alzheimer’s disease, Karl Popper, Amyloid cascade hypothesis, Amyloid-β, Belief, Bibliometrics, Citations, Confirmation, Reproducibility, Scientific bias, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/32250306; hal-02989156; https://hal.sorbonne-universite.fr/hal-02989156; https://hal.sorbonne-universite.fr/hal-02989156/document; https://hal.sorbonne-universite.fr/hal-02989156/file/Daly_JAD_Manuscript.pdf; PUBMED: 32250306

الاتاحة: https://hal.sorbonne-universite.fr/hal-02989156
https://hal.sorbonne-universite.fr/hal-02989156/document
https://hal.sorbonne-universite.fr/hal-02989156/file/Daly_JAD_Manuscript.pdf
https://doi.org/10.3233/JAD-191321