المؤلفون: Benndorf, Rainer, Velazquez, Ryan, Zehr, Jordan D, Pond, Sergei L Kosakovsky, Martin, Jody L, Lucaci, Alexander G

المصدر: Cell Stress and Chaperones. 27(4)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Evolutionary Biology, Biotechnology, Genetics, 2.1 Biological and endogenous factors, Aetiology, Generic health relevance, Animals, Heat-Shock Proteins, Heat-Shock Proteins, Small, Humans, Molecular Chaperones, Mutation, Vertebrates, alpha-Crystallin B Chain, alpha-Crystallins, Purifying selection, Neuropathy, Myopathy, Disease-associated missense mutation, Genetic dominance, Genotype-phenotype relationship, Alpha B-crystallin, Genetic dominance, Neuropathy,  Myopathy, Biochemistry and Cell Biology, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3rs7d3t4
https://escholarship.org/content/qt3rs7d3t4/qt3rs7d3t4.pdf

المؤلفون: Sreekumar, Parameswaran G, Reddy, Srinivasa T, Hinton, David R, Kannan, Ram

مصطلحات موضوعية: Biomedical and Clinical Sciences, Ophthalmology and Optometry, Aging, Neurosciences, Eye Disease and Disorders of Vision, Neurodegenerative, Macular Degeneration, 2.1 Biological and endogenous factors, Aetiology, Eye, Animals, Cellular Senescence, Disease Models, Animal, Fibrosis, Hydrogen Peroxide, Mice, Oxidative Stress, Peptides, Retinal Degeneration, Retinal Pigment Epithelium, alpha-Crystallin B Chain, alpha B crystallin peptide, Mitochondrial dysfunction, Oxidative stress, Retinal pigment epithelium, SASP, Senescence, Senolytic drugs, Subretinal fibrosis, αB crystallin peptide, Medical Biochemistry and Metabolomics, Opthalmology and Optometry, Ophthalmology & Optometry, Ophthalmology and optometry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/28v6c4qg

المؤلفون: Sprague-Piercy, Marc A, Rocha, Megan A, Kwok, Ashley O, Martin, Rachel W

المصدر: Annual Review of Physical Chemistry. 72(1)

مصطلحات موضوعية: Eye Disease and Disorders of Vision, Generic health relevance, Animals, Crystallography, X-Ray, Fishes, Humans, Lens, Crystalline, Molecular Chaperones, Nuclear Magnetic Resonance, Biomolecular, Protein Conformation, Solubility, alpha-Crystallins, alpha-crystallin, protein solubility, vertebrate lens protein, molecular chaperone, protein oligomer, intermolecular interactions, α-crystallin, Physical Chemistry (incl. Structural), Theoretical and Computational Chemistry, Chemical Physics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0xm5t1vz

المؤلفون: Saglam, Aybike, Calof, Anne L, Wray, Susan

المصدر: Glia. 69(4)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Brain Disorders, 2.1 Biological and endogenous factors, Neurological, Anti-Inflammatory Agents, Astrocytes, Cells, Cultured, Humans, Nerve Regeneration, Neuroglia, Neuroinflammatory Diseases, Olfactory Bulb, alpha-Crystallins, alpha‐, crystallin B, astrocyte, exosome, neuroinflammation, neurotoxicity, nuclear factor kappa B (NFκ, B), olfactory ensheathing cells, alpha-crystallin B, nuclear factor kappa B, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/14r3p8sz
https://escholarship.org/content/qt14r3p8sz/qt14r3p8sz.pdf

المؤلفون: Warmack, Rebeccah A, Shawa, Harrison, Liu, Kate, Lopez, Katia, Loo, Joseph A, Horwitz, Joseph, Clarke, Steven G

المصدر: The Journal of biological chemistry. 294(32)

مصطلحات موضوعية: Lens, Crystalline, Humans, Protein D-Aspartate-L-Isoaspartate Methyltransferase, Isoaspartic Acid, Peptides, Crystallins, alpha-Crystallin A Chain, alpha-Crystallin B Chain, Recombinant Proteins, Chromatography, High Pressure Liquid, Amino Acid Sequence, Isomerism, Mass Spectrometry, Protein Aggregates, L-isoaspartate, aging, lens, post-translational modification, protein aggregation, protein degradation, Eye Disease and Disorders of Vision, Aging, Chemical Sciences, Biological Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5q44w5f9
https://escholarship.org/content/qt5q44w5f9/qt5q44w5f9.pdf

المؤلفون: Lyon, Yana A, Collier, Miranda P, Riggs, Dylan L, Degiacomi, Matteo T, Benesch, Justin LP, Julian, Ryan R

المصدر: Journal of Biological Chemistry. 294(19)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 2.1 Biological and endogenous factors, Aetiology, Aging, Humans, Phosphorylation, Protein Aggregates, Protein Domains, Protein Multimerization, alpha-Crystallin A Chain, alpha-Crystallin B Chain, aging, mass spectrometry, radical, chaperone, protein structure, protein self-assembly, protein phosphorylation, protein chemical modification, molecular dynamics, epimer, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0hg332c4
https://escholarship.org/content/qt0hg332c4/qt0hg332c4.pdf

المؤلفون: Sprague-Piercy, Marc A, Wong, Eric, Roskamp, Kyle W, Fakhoury, Joseph N, Freites, J Alfredo, Tobias, Douglas J, Martin, Rachel W

المصدر: Biochimica et Biophysica Acta (BBA) - General Subjects. 1864(3)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Aging, Eye Disease and Disorders of Vision, 2.1 Biological and endogenous factors, Generic health relevance, Cataract, Humans, Hydrophobic and Hydrophilic Interactions, Lens, Crystalline, Molecular Chaperones, Molecular Dynamics Simulation, Mutation, Protein Binding, Protein Conformation, Protein Folding, Structure-Activity Relationship, alpha-Crystallin B Chain, gamma-Crystallins, Pharmacology and Pharmaceutical Sciences, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8bq2k5xx
https://escholarship.org/content/qt8bq2k5xx/qt8bq2k5xx.pdf

المؤلفون: De Maio, Antonio, Cauvi, David M, Capone, Ricardo, Bello, Ivan, Egberts, Wilma Vree, Arispe, Nelson, Boelens, Wilbert

المصدر: Cell Stress and Chaperones. 24(5)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 1.1 Normal biological development and functioning, Underpinning research, Extracellular Vesicles, HeLa Cells, Heat-Shock Proteins, Hep G2 Cells, Humans, Liposomes, Membranes, Molecular Chaperones, Phosphatidylcholines, Phosphatidylglycerols, Phosphatidylserines, Phospholipids, alpha-Crystallin B Chain, Heat shock proteins, Exosomes, Membrane, Stress, Hela Cells, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9wp7v125

المؤلفون: Molnar, Kathleen S, Dunyak, Bryan M, Su, Bonnie, Izrayelit, Yevgeniy, McGlasson-Naumann, Brittney, Hamilton, Paul D, Qian, Mingxing, Covey, Douglas F, Gestwicki, Jason E, Makley, Leah N, Andley, Usha P

المصدر: Investigative Ophthalmology & Visual Science. 60(10)

مصطلحات موضوعية: Eye Disease and Disorders of Vision, Administration, Ophthalmic, Animals, Cataract, Chromatography, Gel, Disease Models, Animal, Fluorometry, Lens, Crystalline, Mice, Mice, Inbred C57BL, Microscopy, Electron, Transmission, Ophthalmic Solutions, Oxysterols, Protein Aggregation, Pathological, Slit Lamp, alpha-Crystallin B Chain, alpha B-crystallin, enantiomer, pharmacologic chaperone, biophysical assay, in vivo cataract model, Biological Sciences, Medical and Health Sciences, Ophthalmology & Optometry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/64t1m25f

المؤلفون: Suk, Jaewon, Sroge, Collin

مصطلحات موضوعية: Nuclear Magnetic Resonance Spectroscopy, Circular Dichroism, Crystallin, Alpha Crystallin Chaperone, Dynamic Light Scattering, Intrinsically Disordered Protein, Protein Unfolding

Relation: https://dx.doi.org/10.17632/fgf3pm3bsg

الاتاحة: https://dx.doi.org/10.17632/fgf3pm3bsg.1
https://data.mendeley.com/datasets/fgf3pm3bsg/1

المؤلفون: Lennikov, Anton, Saddala, Madhu, Mukwaya, Anthony, Tang, Shibo, Huang, Hu

مصطلحات موضوعية: AMD, CRYAA, CRYAB, CXCL13, CXCR5, age macular degeneration, amyloid beta, autoantibody, Amyloid beta-Peptides, Animals, Autoimmunity, Calcium-Binding Proteins, Cell Line, Cyclooxygenase 2, Disease Models, Animal, Fluorescent Antibody Technique, Macular Degeneration, Mice, Inbred C57BL, Mice, Knockout, Microfilament Proteins, Microglia, Microscopy, Electron, Transmission, Receptors, CXCR5, Retinal Degeneration, Retinal Pigment Epithelium, Vascular Endothelial Growth Factor A, Zonula Occludens-1 Protein, alpha-Crystallin B Chain

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9z998640
https://escholarship.org/content/qt9z998640/qt9z998640.pdf

المؤلفون: Konstantin O. Muranov, Nicolay B. Poliansky, Vera A. Borzova, Sergey Y. Kleimenov

المصدر: International Journal of Molecular Sciences ; Volume 24 ; Issue 17 ; Pages: 13473

مصطلحات موضوعية: alpha-crystallin, alphaH-crystallin, high molecular weight aggregate, chaperone, chaperone-like activity, refolding, urea

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Macromolecules; https://dx.doi.org/10.3390/ijms241713473

الاتاحة: https://doi.org/10.3390/ijms241713473

المؤلفون: Xu, Na, Bitan, Gal, Schrader, Thomas, Klärner, Frank-Gerrit, Osinska, Hanna, Robbins, Jeffrey

المصدر: Journal of the American Heart Association. 6(8)

مصطلحات موضوعية: Cells, Cultured, Myocytes, Cardiac, Animals, Mice, Transgenic, Rats, Rats, Sprague-Dawley, Adenoviridae, Organophosphorus Compounds, Proteasome Endopeptidase Complex, alpha-Crystallin B Chain, Transduction, Genetic, Transfection, Protein Folding, Dose-Response Relationship, Drug, Mutation, Genetic Vectors, Time Factors, Ubiquitination, Proteolysis, Organophosphates, Protein Aggregates, Protein Aggregation, Pathological, Bridged-Ring Compounds, amyloid, animal model cardiovascular disease, cardiomyopathy, chaperones, proteasome, Cardiovascular, Heart Disease, 2.1 Biological and endogenous factors, Cardiorespiratory Medicine and Haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9bv2c0qw

المؤلفون: Makley, Leah N, McMenimen, Kathryn A, DeVree, Brian T, Goldman, Joshua W, McGlasson, Brittney N, Rajagopal, Ponni, Dunyak, Bryan M, McQuade, Thomas J, Thompson, Andrea D, Sunahara, Roger, Klevit, Rachel E, Andley, Usha P, Gestwicki, Jason E

المصدر: Science. 350(6261)

مصطلحات موضوعية: Eye Disease and Disorders of Vision, Aging, Amyloid, Animals, Calorimetry, Differential Scanning, Cataract, Disease Models, Animal, Gene Knock-In Techniques, Humans, Hydroxycholesterols, Mice, Protein Conformation, Protein Stability, alpha-Crystallin A Chain, alpha-Crystallin B Chain, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/12d1q82j

المؤلفون: Gangalum, Rajendra K, Bhat, Ankur M, Kohan, Sirus A, Bhat, Suraj P

المصدر: Journal of Biological Chemistry. 291(25)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Eye Disease and Disorders of Vision, Underpinning research, 2.1 Biological and endogenous factors, Aetiology, 1.1 Normal biological development and functioning, Cell Line, Endosomes, Epithelial Cells, Exosomes, Gene Expression, Gene Knockdown Techniques, Humans, Lysosomal-Associated Membrane Protein 3, Lysosomes, Protein Transport, RNA, Small Interfering, Retinal Pigment Epithelium, Vacuoles, alpha-Crystallin B Chain, rab GTP-Binding Proteins, rab7 GTP-Binding Proteins, CD63, LAMP1, Rab5, Rab7, endosome, exosome complex, lysosome, retinal pigment epithelium, secretion, small heat shock protein, Chemical Sciences, Biological Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3b88x275
https://escholarship.org/content/qt3b88x275/qt3b88x275.pdf

المؤلفون: Oliveira, Ana Osório, Osmand, Alexander, Outeiro, Tiago Fleming, Muchowski, Paul Joseph, Finkbeiner, Steven

المصدر: Human Molecular Genetics. 25(9)

مصطلحات موضوعية: Rare Diseases, Huntington's Disease, Neurosciences, Brain Disorders, Neurodegenerative, 2.1 Biological and endogenous factors, Aetiology, Neurological, Animals, Astrocytes, Behavior, Animal, Brain, Disease Models, Animal, Humans, Huntingtin Protein, Huntington Disease, Mice, Mice, Transgenic, Neurons, Phenotype, alpha-Crystallin B Chain, Biological Sciences, Medical and Health Sciences, Genetics & Heredity

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8nn5z3m6

المؤلفون: Ajamaluddin Malik, Javed Masood Khan, Abdullah S. Alhomida, Mohammad Shamsul Ola

المصدر: Gels; Volume 8; Issue 5; Pages: 273

مصطلحات موضوعية: alpha-crystallin, dynamic multimode spectroscopy, circular dichroism, fluorescence, thermal stability

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/gels8050273

الاتاحة: https://doi.org/10.3390/gels8050273

المؤلفون: Kehao Wang, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Barbara K. Pierscionek, Usha P. Andley

مصطلحات موضوعية: refractive index, X-ray, alpha crystallin mutant lenses, oxysterol

Relation: 10779/aru.23781858.v1; https://figshare.com/articles/journal_contribution/Oxysterol_compounds_in_mouse_mutant_A-_and_B-crystallin_lenses_can_improve_the_optical_properties_of_the_lens/23781858

الاتاحة: https://figshare.com/articles/journal_contribution/Oxysterol_compounds_in_mouse_mutant_A-_and_B-crystallin_lenses_can_improve_the_optical_properties_of_the_lens/23781858

المؤلفون: Hochberg, Georg KA, Ecroyd, Heath, Liu, Cong, Cox, Dezerae, Cascio, Duilio, Sawaya, Michael R, Collier, Miranda P, Stroud, James, Carver, John A, Baldwin, Andrew J, Robinson, Carol V, Eisenberg, David S, Benesch, Justin LP, Laganowsky, Arthur

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 111(16)

مصطلحات موضوعية: Neurodegenerative, Neurosciences, Prevention, Underpinning research, 1.1 Normal biological development and functioning, Amino Acid Sequence, Amyloid beta-Peptides, Animals, Crystallization, Cysteine, HEK293 Cells, HSP27 Heat-Shock Proteins, HeLa Cells, Humans, Magnetic Resonance Spectroscopy, Mammals, Molecular Sequence Data, PC12 Cells, Protein Multimerization, Protein Structure, Quaternary, Protein Structure, Tertiary, Rats, Structure-Activity Relationship, alpha-Crystallin B Chain, X-ray crystallography, ion mobility mass spectrometry, nuclear magnetic resonance spectroscopy, Hela Cells

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1sz4f7bj

المؤلفون: Kingsley, Carolyn N, Brubaker, William D, Markovic, Stefan, Diehl, Anne, Brindley, Amanda J, Oschkinat, Hartmut, Martin, Rachel W

المصدر: Structure (London, England : 1993). 21(12)

مصطلحات موضوعية: Humans, Cataract, alpha-Crystallin B Chain, gamma-Crystallins, Protein Conformation, Protein Binding, Mutation, Molecular Dynamics Simulation, Eye Disease and Disorders of Vision, Aging, 2.1 Biological and endogenous factors, Aetiology, Chemical Sciences, Biological Sciences, Information and Computing Sciences, Biophysics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5tb4462c