المؤلفون: Kai‐Ming Zhang, De‐Chang Zhao, Ze‐Yu Li, Yan Wang, Jian‐Nan Liu, Tian Du, Ling Zhou, Yu‐Hong Chen, Qi‐Chao Yu, Qing‐Shan Chen, Rui‐Zhao Cai, Zi‐Xuan Zhao, Jia‐Lu Shan, Bing‐Xin Hu, Hai‐Liang Zhang, Gong‐Kan Feng, Xiao‐Feng Zhu, Jun Tang, Rong Deng

المصدر: Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)

مصطلحات موضوعية: AKT kinase, cGAS‐STING pathway, endocrine‐resistant breast cancer, positive feedback loop, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2198-3844

URL الوصول: https://doaj.org/article/0bb97eb8b1b84525bea91c117811fad7

المؤلفون: Karin Fehsel

المصدر: Biomedicines, Vol 12, Iss 10, p 2294 (2024)

مصطلحات موضوعية: hyperglycemia, Akt kinase, brain, adipogenesis, interleukin 6, glucose transporter, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/10/2294; https://doaj.org/toc/2227-9059

URL الوصول: https://doaj.org/article/093981f28b3c47c280018d4e85e8fe89

المؤلفون: Satoshi Nishino, Yoko Fujiki, Takanari Sato, Yukino Kato, Remina Shirai, Hiroaki Oizumi, Masahiro Yamamoto, Katsuya Ohbuchi, Yuki Miyamoto, Kazushige Mizoguchi, Junji Yamauchi

المصدر: Neurology International, Vol 14, Iss 2, Pp 471-487 (2022)

مصطلحات موضوعية: oligodendrocyte, differentiation, TNFα, IL-6, hesperetin, Akt kinase, Medicine, Internal medicine, RC31-1245, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2035-8377/14/2/39; https://doaj.org/toc/2035-8377

URL الوصول: https://doaj.org/article/7e445673444b437f8f30e1e6791198ac

المؤلفون: Elaine, Angela Alysia, Nisa, Akhyatun, Tahara, Nabila, Aini, Dzulfah Qurrotul, Syahriar, Zulvan

المصدر: Indonesian Journal of Biological Pharmacy; Vol 3, No 1 (2023): IJBP (April); 19-32 ; 2807-4173 ; 2807-5277 ; 10.24198/ijbp.v3i1

مصطلحات موضوعية: Kimia Medisinal, Studi Komputasi, Pancreatic cancer, AKT kinase protein, xanthone compounds, mangosteen, molecular docking

وصف الملف: application/pdf

Relation: http://jurnal.unpad.ac.id/ijbp/article/view/42601/pdf; http://jurnal.unpad.ac.id/ijbp/article/view/42601

الاتاحة: http://jurnal.unpad.ac.id/ijbp/article/view/42601
https://doi.org/10.24198/ijbp.v3i1.42601

المؤلفون: Jaroslav Kalous, Daria Aleshkina, Martin Anger

المصدر: Cells; Volume 12; Issue 14; Pages: 1830

مصطلحات موضوعية: Akt kinase, mTORC1, mitosis, meiosis, spindle, oocyte, early embryo, mRNA translation

وصف الملف: application/pdf

Relation: Cell Proliferation and Division; https://dx.doi.org/10.3390/cells12141830

الاتاحة: https://doi.org/10.3390/cells12141830

المؤلفون: Hamilton, Nalo, Austin, David, Márquez-Garbán, Diana, Sanchez, Rudy, Chau, Brittney, Foos, Kay, Wu, Yanyuan, Vadgama, Jaydutt, Pietras, Richard

المصدر: International journal of molecular sciences. 18(11)

مصطلحات موضوعية: Cell Line, Tumor, Humans, Phenylthiohydantoin, Pyrazoles, Pyrimidines, Pyrroles, Triazines, Androgen Antagonists, Receptor, IGF Type 1, Insulin-Like Growth Factor II, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Androgens, Signal Transduction, Cell Proliferation, Cell Survival, Female, Molecular Targeted Therapy, Triple Negative Breast Neoplasms, AKT kinase, BMS-754807, IGF1R/IR inhibition, IGF2 signaling, NVP-AEW541, androgen receptor, apoptosis, enzalutamide, insulin-like growth factor-2, triple-negative breast cancer, IGF1R, IR inhibition, Cell Line, Tumor, Receptor, IGF Type 1, Other Chemical Sciences, Genetics, Other Biological Sciences, Chemical Physics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1qg5t0jx

المؤلفون: Westhuizen, Leandi van der, Weisner, Jörn, Taher, Abu, Landel, Ina, Quambusch, Lena, Lindemann, Marius, Uhlenbrock, Niklas, Müller, Matthias P., Green, Ivan R., Pelly, Stephen C., Rauh, Daniel, Otterlo, Willem A. L. van

مصطلحات موضوعية: ddc:570, ddc:540, Akt kinase, covalent allosteric inhibitors, imidazopyridines, click chemistry, fragments

Relation: ChemMedChem;17(10); http://hdl.handle.net/2003/42375; http://dx.doi.org/10.17877/DE290R-24212

الاتاحة: http://hdl.handle.net/2003/42375
https://doi.org/10.17877/DE290R-24212

المؤلفون: Maria Kourti, Danai Liaropoulou, Maria Paschou, Ioanna Giagklisi, Maria Paschalidi, Evangelia Petani, Panagiota Papazafiri

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1386

مصطلحات موضوعية: ischemia, hypoxia, glucose deprivation, Akt kinase, hypoxia-inducible factor 1, Ca 2+ entry

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biology; https://dx.doi.org/10.3390/ijms23031386

الاتاحة: https://doi.org/10.3390/ijms23031386

المؤلفون: Procházka, Radek, Bartková, Alexandra, Němcová, Lucie, Murín, Matej, Gad, Ahmed, Marcollová, Kateřina, Kinterová, Veronika, Lucas-Hahn, Andrea, Laurinčík, Jozef

مصطلحات موضوعية: article, Text, ddc:570, AKT kinase, FGF2, Gene expression, IGF1, LIF, MAP kinase 3/1, Oocyte competence, Oocyte maturation

Relation: International Journal of Molecular Sciences -- Int J Mol Sci -- IJMS -- 1422-0067 -- 1661-6596 -- 2019364-6 -- http://www.mdpi.com/journal/ijms -- https://www.ncbi.nlm.nih.gov/pmc/journals/808/ -- http://www.bibliothek.uni-regensburg.de/ezeit/?2019364; https://doi.org/10.3390/ijms222011148; https://www.openagrar.de/receive/openagrar_mods_00075166; https://www.openagrar.de/servlets/MCRFileNodeServlet/openagrar_derivate_00042560/ijms-22-11148-v2.pdf; https://www.mdpi.com/1422-0067/22/20/11148/pdf; https://www.mdpi.com/1422-0067/22/20/11148

الاتاحة: https://doi.org/10.3390/ijms222011148
https://www.openagrar.de/receive/openagrar_mods_00075166
https://www.openagrar.de/servlets/MCRFileNodeServlet/openagrar_derivate_00042560/ijms-22-11148-v2.pdf
https://www.mdpi.com/1422-0067/22/20/11148/pdf
https://www.mdpi.com/1422-0067/22/20/11148

المؤلفون: Yuhei Nishimura, Daishi Yamakawa, Takashi Shiromizu, Masaki Inagaki

المصدر: Cells; Volume 10; Issue 12; Pages: 3602

مصطلحات موضوعية: primary cilium, aurora kinase A, AKT kinase, trichoplein, lipid raft, proliferation, differentiation, cancer, obesity, ciliopathy

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cells10123602

الاتاحة: https://doi.org/10.3390/cells10123602

المؤلفون: Vasylyna Kovalchuk, Katarzyna A. Nałęcz

المصدر: Cells; Volume 10; Issue 7; Pages: 1800

مصطلحات موضوعية: amino acid transporter, SLC6A14, AKT kinase, SEC24C, breast cancer

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cells10071800

الاتاحة: https://doi.org/10.3390/cells10071800

المؤلفون: Barbora Pavlatovská, Markéta Machálková, Petra Brisudová, Adam Pruška, Karel Štěpka, Jan Michálek, Tereza Nečasová, Petr Beneš, Jan Šmarda, Jan Preisler, Michal Kozubek, Jarmila Navrátilová

المصدر: Frontiers in Oncology, Vol 10 (2020)

مصطلحات موضوعية: perifosine, Akt kinase, tumor environment, lactic acidosis, alkalization, signal co-registration, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2020.581365/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/9ed970cdc0f84726b73a3e573feb023d

المؤلفون: Orike, Nina, Middleton, Gayle, Borthwick, Emma, Buchman, Vladimir, Cowen, Timothy, Davies, Alun M.

المصدر: The Journal of Cell Biology, 2001 Sep 01. 154(5), 995-1005.

URL الوصول: https://www.jstor.org/stable/1620762

المؤلفون: Peters, Linsey J. F., Floege, Juergen, Biessen, Erik A. L., Jankowski, Joachim, van der Vorst, Emiel P. C.

المصدر: Peters , L J F , Floege , J , Biessen , E A L , Jankowski , J & van der Vorst , E P C 2020 , ' MicroRNAs in Chronic Kidney Disease : Four Candidates for Clinical Application ' , International journal of molecular sciences , vol. 21 , no. 18 , 6547 . https://doi.org/10.3390/ijms21186547

مصطلحات موضوعية: MicroRNAs, kidney fibrosis, chronic kidney disease, clinical application, PROMOTES RENAL FIBROSIS, DIABETIC-NEPHROPATHY, DOWN-REGULATION, COLLAGEN EXPRESSION, HIGH GLUCOSE, MESENCHYMAL TRANSITION, CARDIORENAL SYNDROME, ANGIOTENSIN-II, MOUSE MODEL, AKT KINASE

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/ab0b213b-2307-458f-b75f-3da9606c8b2e
https://doi.org/10.3390/ijms21186547

المؤلفون: Klaudia Skrzypek, Marta Kot, Paweł Konieczny, Artur Nieszporek, Anna Kusienicka, Małgorzata Lasota, Wojciech Bobela, Urszula Jankowska, Sylwia Kędracka-Krok, Marcin Majka

المصدر: Cancers; Volume 12; Issue 7; Pages: 1870

مصطلحات موضوعية: rhabdomyosarcoma (RMS), tumor metastasis, SNAIL transcription factor, microRNA (miRNA), EZRIN, AKT kinase

وصف الملف: application/pdf

Relation: Tumor Microenvironment; https://dx.doi.org/10.3390/cancers12071870

الاتاحة: https://doi.org/10.3390/cancers12071870

المؤلفون: Pavlatovská, Barbora, Machálková, Markéta, Brisudová, Petra, Pruska, Adam, id_orcid:0 000-0002-5304-2541, Štěpka, Karel, Michálek, Jan, Nečasová, Tereza, Beneš, Petr, Šmarda, Jan, Preisler, Jan, Kozubek, Michal, Navrátilová, Jarmila

المصدر: Frontiers in Oncology, 10

مصطلحات موضوعية: Perifosine, Akt kinase, Tumor environment, Lactic acidosis, Alkalization, Signal co-registration, Mass spectrometry imaging, Colorectal cancer

وصف الملف: application/application/pdf

Relation: info:eu-repo/semantics/altIdentifier/wos/000599610600001; http://hdl.handle.net/20.500.11850/458586

الاتاحة: https://hdl.handle.net/20.500.11850/458586
https://doi.org/10.3929/ethz-b-000458586

المؤلفون: A. Shpakov O., А. Шпаков О.

المساهمون: Работа поддержана грантом РФФИ и ДНТ (№ 18-515-45004 ИНД-a) и частично госзаданием АААА-А18-118012290427-7

المصدر: Translational Medicine; Том 6, № 2 (2019); 25-36 ; Трансляционная медицина; Том 6, № 2 (2019); 25-36 ; 2410-5155 ; 2311-4495 ; 10.18705/2311-4495-2019-6-2

مصطلحات موضوعية: visfatin, ovaries, folliculogenesis, steroidogenesis, mitogen-activated protein kinase, Akt-kinase, hypothalamic-pituitary-gonad axis, reproductive function, gonadotropin, gonadoliberin, висфатин, яичники, фолликулогенез, стероидогенез, митогенактивирумая протеинкиназа, Akt-киназа, гипоталамо-гипофизарно-гонадная ось, репродуктивные функции, гонадотропин, гонадолиберин

وصف الملف: application/pdf

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Crucial Role of Visfatin/Pre-B Cell Colony-Enhancing Factor in Matrix Degradation and Prostaglandin E2 Synthesis in Chondrocytes: Possible Influence on Osteoarthritis. Arthritis Rheum. 2008;58(5):1399-1409.; Zhong M, Tan HW, Gong HP et al. Increased Serum Visfatin in Patients with Metabolic Syndrome and Carotid Atherosclerosis. Clin Endocrinol (Oxf). 2008;69(6):878-884.; Косыгина А. В., Васюкова О. В. Новое в патогенезе ожирения: адипоки-ны - гормоны жировой ткани. Проблемы эндокринологии. 2009;55(1):44-50.; Косыгина А. В., Сосунов В. В., Петеркова В. А. и др. Экспрессия гена адипонектина (ADIPOQ) в подкожной и висцеральной жировой ткани и уровень адипонектина в сыворотке крови у детей. Проблемы эндокринологии. 2010;56(6):3-8.; Dupont J, Pollet-Villard X, Reverchon M et al. Adipokines in Human Reproduction. Horm Mol Biol Clin Investig. 2015;24(1):11-24.; Shpakov AO, Derkach KV, Berstein LM. Brain Signaling Systems in the Type 2 Diabetes and Metabolic Syndrome: Promising Target to Treat and Prevent These Diseases. Future Sci OA. 2015;1(3):FSO25.; Сорокоумов В. Н., Шпаков А. О. Протеин-фосфотирозинфосфатаза 1B: структура, функции, роль в развитии метаболических расстройств и их коррекция с помощью ингибиторов фермента. Журнал эволюционной биохимии и физиологии. 2017;53(4):230-240.; Romanova IV, Derkach KV, Mikhrina AL et al. The Leptin, Dopamine and Serotonin Receptors in Hypothalamic POMC-Neurons of Normal and Obese Rodents. Neurochem Res. 2018;43(4):821-837.; Derkach K, Zakharova I, Zorina I et al. The Evidence of Metabolic-Improving Effect of Metformin in Ay/a Mice with Genetically-Induced Melanocortin Obesity and the Contribution of Hypothalamic Mechanisms to This Effect. PLoS One. 2019;14(3):e0213779.; Shen CJ, Tsai Em, Lee JN et al. The Concentrations of Visfatin in the Follicular Fluids of Women Undergoing Controlled Ovarian Stimulation are Correlated to the Number of Oocytes Retrieved. Fertil Steril. 2010;93(6):1844-1850.; Choi KH, Joo BS, Sun ST et al. Administration of Visfatin During Superovulation Improves Developmental Competency of Oocytes and Fertility Potential in Aged Female Mice. Fertil Steril. 2012;97(5):1234-1241.; Reverchon M, Maillard V, Froment P et al. Adiponectin and Resistin: A Role in the Reproductive Functions? Med Sci (Paris). 2013;29(4):417-424.; Reverchon M, Rame C, Bertoldo M et al. Adipokines and the Female Reproductive Tract. Int J Endocrinol. 2014;2014:232454.; Diot M, Reverchon M, Rame C et al. Expression and Effect of NAMPT (Visfatin) on Progesterone Secretion in Hen Granulosa Cells. Reproduction. 2015;150(1):53-63.; Reverchon M, Rame C, Bunel A et al. VISFATIN (NAMPT) Improves In Vitro IGFl-Induced Steroidogenesis and IGF1 Receptor Signaling Through SIRT1 in Bovine Granulosa Cells. Biol Reprod. 2016;94(3):54.; Maillard V, Elis S, Desmarchais A et al. Visfatin and Resistin in Gonadotroph Cells: Expression, Regulation of LH Secretion and Signalling Pathways. Reprod Fertil Dev. 2017;29(12):2479-2495.; Ocon-Grove OM, Krzysik-Walker SM, Maddineni SR et al. NAMPT (Visfatin) in the Chicken Testis: Influence of Sexual Maturation on Cellular Localization, Plasma Levels and Gene and Protein Expression. Reproduction. 2010;139(1):217-226.; Thomas S, Kratzsch D, Schaab M et al. Seminal Plasma Adipokine Levels Are Correlated with Functional Characteristics of Spermatozoa. Fertil Steril. 2013;99(5):1256-1263.; Gurusubramanian G, Roy VK. Expression of Visfatin in Alloxan-Induced Diabetic Rat Testis. Acta Histochem. 2014;116(8):1462-1468.; Riammer S, Garten A, Schaab M et al. Nicotinamide Phosphoribosyltransferase Production in Human Spermatozoa Is Influenced by Maturation Stage. Andrology. 2016;4(6):1045-1053.; Mellouk N, Rame C, Barbe A et al. Chicken Is a Useful Model to Investigate the Role of Adipokines in Metabolic and Reproductive Diseases. Int J Endocrinol. 2018;2018:4579734.; Brunetti L, Recinella L, Di Nisio C et al. Effects of Visfatin/PBEF/NAMPT on Feeding Behaviour and Hypothalamic Neuromodulators in the Rat. J Biol Regul Homeost Agents. 2012;26(2):295-302.; Cline M, Nandar W, Prall BC et al. Central Visfatin Causes Orexigenic Effects in Chicks. Behav Brain Res. 2008;186(2):293-297.; Li Z, Liu X, Zhang P et al. Comparative Transcriptome Analysis of Hypothalamus-Regulated Feed Intake Induced by Exogenous Visfatin in Chicks. BMC Genomics. 2018;19(1):249.; Kim DS, Kang S, Moon NR et al. Central Visfatin Potentiates Glucose-Stimulated Insulin Secretion and P-Cell Mass Without Increasing Serum Visfatin Levels in Diabetic Rats. Cytokine. 2014;6 (2):159-166.; Hameed W, Yousaf I, Latif R et al. Effect of Visfatin on Testicular Steroidogenesis in Purified Leydig Cells. J Ayub Med Coll Abbottabad. 2012;24(3-4):62-64.; Varma V, Yao-Borengasser A, Rasouli N et al. Human Visfatin Expression: Relationship to Insulin Sensitivity, Intramyocellular Lipids, and Inflammation. J Clin Endocrinol Metab. 2007;92(2):666-672.; Al-Suhaimi EA, Shehzad A. Leptin, Resistin and Visfatin: The Missing Link Between Endocrine Metabolic Disorders and Immunity. Eur J Med Res. 2013;18:12.; Wu MH, Tsai cH, Huang YL et al. Visfatin Promotes IL-6 and TNF-a Production in Human Synovial Fibroblasts by Repressing miR-199a-5p Through ERK, p38 and JNK Signaling Pathways. Int J Mol Sci. 2018;19(1). pii:E190.; https://transmed.almazovcentre.ru/jour/article/view/454

الاتاحة: https://transmed.almazovcentre.ru/jour/article/view/454
https://doi.org/10.18705/2311-4495-2019-6-2-25-36

المؤلفون: Agata Majchrzak, Magdalena Witkowska, Piotr Smolewski

المصدر: Molecules, Vol 19, Iss 9, Pp 14304-14315 (2014)

مصطلحات موضوعية: diffuse large B-cell lymphoma, PI3K kinase, Akt kinase, mTOR kinase, inhibitor, treatment, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/19/9/14304; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/317b151feb914dae90866033e2450c99

المؤلفون: Navrátilová Jarmila, Karasová Martina, Kohutková Lánová Martina, Jiráková Ludmila, Budková Zuzana, Pacherník Jiří, Šmarda Jan, Beneš Petr

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: neuroblastoma, tetrathiomolybdate, Akt kinase, cell viability, glycolysis, exygen consumtion, metabolic plasticity

Relation: https://is.muni.cz/publication/1386680

الاتاحة: https://is.muni.cz/publication/1386680
https://doi.org/10.1111/jcmm.13106

المؤلفون: Nalo Hamilton, David Austin, Diana Márquez-Garbán, Rudy Sanchez, Brittney Chau, Kay Foos, Yanyuan Wu, Jaydutt Vadgama, Richard Pietras

المصدر: International Journal of Molecular Sciences; Volume 18; Issue 11; Pages: 2305

مصطلحات موضوعية: triple-negative breast cancer, insulin-like growth factor-2, androgen receptor, BMS-754807, NVP-AEW541, enzalutamide, IGF1R/IR inhibition, IGF2 signaling, AKT kinase, apoptosis

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms18112305

الاتاحة: https://doi.org/10.3390/ijms18112305