المؤلفون: Yan J. Sheng, Syuan-Ting A. Kuo, Tingyuan Yang, Hanyuan E. Zhang, David H. Russell, Xin Yan, Shiqing Xu, Wenshe R. Liu, Carol A. Fierke

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Immunology, Infectious Diseases, Chemical Sciences not elsewhere classified, coronavirus disease 2019, addition reaction mechanism, dependent histone deacetylases, 9 ± 0, 72 ± 0, 5 μm followed, 040 ± 0, catalytic cysteine c145, brd4354 displays time, max , pro , potent covalent inhibitor, 50 , potent inhibitor, , dependent inhibition, 50 %), 04 μm, vitro <, ortho <, k <, covalent intermediate

Relation: https://figshare.com/articles/journal_contribution/BRD4354_Is_a_Potent_Covalent_Inhibitor_against_the_SARS-CoV_2_Main_Protease/25188336

الاتاحة: https://doi.org/10.1021/acs.biochem.3c00685.s001
https://figshare.com/articles/journal_contribution/BRD4354_Is_a_Potent_Covalent_Inhibitor_against_the_SARS-CoV_2_Main_Protease/25188336

المؤلفون: Yan J. Sheng, Syuan-Ting A. Kuo, Tingyuan Yang, Hanyuan E. Zhang, David H. Russell, Xin Yan, Shiqing Xu, Wenshe R. Liu, Carol A. Fierke

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Immunology, Infectious Diseases, Chemical Sciences not elsewhere classified, coronavirus disease 2019, addition reaction mechanism, dependent histone deacetylases, 9 ± 0, 72 ± 0, 5 μm followed, 040 ± 0, catalytic cysteine c145, brd4354 displays time, max , pro , potent covalent inhibitor, 50 , potent inhibitor, , dependent inhibition, 50 %), 04 μm, vitro <, ortho <, k <, covalent intermediate

Relation: https://figshare.com/articles/journal_contribution/BRD4354_Is_a_Potent_Covalent_Inhibitor_against_the_SARS-CoV_2_Main_Protease/25188339

الاتاحة: https://doi.org/10.1021/acs.biochem.3c00685.s002
https://figshare.com/articles/journal_contribution/BRD4354_Is_a_Potent_Covalent_Inhibitor_against_the_SARS-CoV_2_Main_Protease/25188339

المؤلفون: Yan J. Sheng, Syuan-Ting A. Kuo, Tingyuan Yang, Hanyuan E. Zhang, David H. Russell, Xin Yan, Shiqing Xu, Wenshe R. Liu, Carol A. Fierke

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Immunology, Infectious Diseases, Chemical Sciences not elsewhere classified, coronavirus disease 2019, addition reaction mechanism, dependent histone deacetylases, 9 ± 0, 72 ± 0, 5 μm followed, 040 ± 0, catalytic cysteine c145, brd4354 displays time, max , pro , potent covalent inhibitor, 50 , potent inhibitor, , dependent inhibition, 50 %), 04 μm, vitro <, ortho <, k <, covalent intermediate

Relation: https://figshare.com/articles/journal_contribution/BRD4354_Is_a_Potent_Covalent_Inhibitor_against_the_SARS-CoV_2_Main_Protease/25188336

الاتاحة: https://doi.org/10.1021/acs.biochem.3c00685.s001

المؤلفون: Yan J. Sheng, Syuan-Ting A. Kuo, Tingyuan Yang, Hanyuan E. Zhang, David H. Russell, Xin Yan, Shiqing Xu, Wenshe R. Liu, Carol A. Fierke

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Immunology, Infectious Diseases, Chemical Sciences not elsewhere classified, coronavirus disease 2019, addition reaction mechanism, dependent histone deacetylases, 9 ± 0, 72 ± 0, 5 μm followed, 040 ± 0, catalytic cysteine c145, brd4354 displays time, max , pro , potent covalent inhibitor, 50 , potent inhibitor, , dependent inhibition, 50 %), 04 μm, vitro <, ortho <, k <, covalent intermediate

Relation: https://figshare.com/articles/journal_contribution/BRD4354_Is_a_Potent_Covalent_Inhibitor_against_the_SARS-CoV_2_Main_Protease/25188339

الاتاحة: https://doi.org/10.1021/acs.biochem.3c00685.s002

المؤلفون: CANOVESE, Luciano, VISENTIN, Fabiano, SCATTOLIN, THOMAS, SANTO, Claudio, Bertolasi, Valerio

المساهمون: Canovese, Luciano, Visentin, Fabiano, Scattolin, Thoma, Santo, Claudio, Bertolasi, Valerio

مصطلحات موضوعية: Thioquinoline Pt(0) complexes,Olefin exchange,Alkyl halides oxidative addition,Reaction mechanism,X-ray structural determination, Settore CHIM/03 - Chimica Generale e Inorganica

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000401382500029; volume:129; firstpage:229; lastpage:239; numberofpages:11; journal:POLYHEDRON; http://hdl.handle.net/10278/3685856; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85017593737

الاتاحة: http://hdl.handle.net/10278/3685856
https://doi.org/10.1016/j.poly.2017.03.053