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1Academic Journal
المؤلفون: Kayoko Ohura, Mizuki Isozaki, Teruko Imai
المصدر: Biological and Pharmaceutical Bulletin. 2022, 45(10):1544
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2Academic Journal
المؤلفون: Fanny L. Lemarié, Nicholas S. Caron, Shaun S. Sanders, Mandi E. Schmidt, Yen T.N. Nguyen, Seunghyun Ko, Xiaohong Xu, Mahmoud A. Pouladi, Dale D.O. Martin, Michael R. Hayden
المصدر: Neurobiology of Disease, Vol 158, Iss , Pp 105479- (2021)
مصطلحات موضوعية: Palmitoylation, S-acylation, Huntingtin, Huntington disease, ZDHHC17, Acyl-protein thioesterase, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Luke H. Chamberlain, Michael J. Shipston, Gwyn W. Gould
المصدر: Open Biology, Vol 11, Iss 3 (2021)
مصطلحات موضوعية: s-acylation, zdhhc enzymes, acyl protein thioesterase, insulin secretion, insulin signalling, glut4, Biology (General), QH301-705.5
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2046-2441
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4Academic Journal
المؤلفون: Laurence Abrami, Tiziano Dallavilla, Patrick A Sandoz, Mustafa Demir, Béatrice Kunz, Georgios Savoglidis, Vassily Hatzimanikatis, F Gisou van der Goot
المصدر: eLife, Vol 6 (2017)
مصطلحات موضوعية: palmitoylation, ERAD, DHHC, turnover, Acyl protein thioesterase, endoplasmic reticulum, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Alyssa L. Bolen, Anjaparavanda P. Naren, Sunitha Yarlagadda, Sarka Beranova-Giorgianni, Li Chen, Derek Norman, Daniel L. Baker, Meng M. Rowland, Michael D. Best, Takamitsu Sano, Tamotsu Tsukahara, Karoly Liliom, Yasuyuki Igarashi, Gabor Tigyi
المصدر: Journal of Lipid Research, Vol 52, Iss 5, Pp 958-970 (2011)
مصطلحات موضوعية: lysophospholipid, acyl protein thioesterase, autotoxin, lysophosphatidic acid, Biochemistry, QD415-436
وصف الملف: electronic resource
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6
المؤلفون: Peipei Yan, Eryan Kong, Huicong Liu, Junyan Ren, Wei Yuan, Muding Rao, Zhongjian Zhang, Can Wu
المصدر: Current Molecular Medicine. 19:364-375
مصطلحات موضوعية: 0301 basic medicine, Endoplasmic Reticulum, Proteomics, medicine.disease_cause, Biochemistry, Cell Line, Substrate Specificity, 03 medical and health sciences, 0302 clinical medicine, Palmitoylation, Thioesterase, medicine, Humans, Gene Regulatory Networks, Molecular Biology, Cells, Cultured, Cell Proliferation, Mutation, Chemistry, Gene Expression Profiling, Endoplasmic reticulum, HEK 293 cells, Computational Biology, PPT1, General Medicine, Cell biology, HEK293 Cells, 030104 developmental biology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Molecular Medicine, Acyl-Protein Thioesterase 1, Thiolester Hydrolases
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7
المؤلفون: Fangfang Zhou, Fangwei Wang, Linghui Zeng, Huizhe Huang, Jun Huang, Heyu Li, Long Zhang, Haiyan Yan, Peng Su, Ting Pan, Xiaoxue Zhou, Feng Xie, Aijun Wang
المصدر: Advanced Materials (Deerfield Beach, Fla.)
مصطلحات موضوعية: Materials science, Cell, ACE2, SARS‐CoV‐2, Extracellular Vesicles, Mice, Palmitoylation, medicine, Animals, General Materials Science, Secretion, Protein palmitoylation, palmitoylation, Receptor, Research Articles, Zinc finger, SARS-CoV-2, Mechanical Engineering, In vitro, Cell biology, COVID-19 Drug Treatment, medicine.anatomical_structure, Mechanics of Materials, Spike Glycoprotein, Coronavirus, Acyl-Protein Thioesterase 1, Angiotensin-Converting Enzyme 2, Thiolester Hydrolases, hormones, hormone substitutes, and hormone antagonists, Protein Binding, Research Article
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8
المؤلفون: Shaun S. Sanders, Jordan A. Kogut, Charlotte A. Townsend, Andrey A. Petropavlovskiy, Arshia Leekha
المصدر: Neuronal Signaling
مصطلحات موضوعية: axon, palmitoyl acyltransferase, technology, industry, and agriculture, acyl protein thioesterase, S-acylation, Biology, medicine.disease_cause, Axon initial segment, axon initial segment, Cell biology, medicine.anatomical_structure, Palmitoylation, Protein targeting, medicine, palmitoylation, lipids (amino acids, peptides, and proteins), Protein palmitoylation, Axon, Palmitoyl acyltransferase, Review Articles, Neuroscience, Action potential initiation
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9
المؤلفون: Dale D.O. Martin, Yen T. Nguyen, Mandi E. Schmidt, Fanny Lemarié, Michael R. Hayden, Mahmoud A. Pouladi, Shaun S. Sanders, Nicholas S. Caron, Seunghyun Ko, Xiaohong Xu
المصدر: Neurobiology of Disease, Vol 158, Iss, Pp 105479-(2021)
مصطلحات موضوعية: Male, Huntingtin, Mutant, Pathogenesis, Mice, 0302 clinical medicine, Chlorocebus aethiops, Lymphocytes, Enzyme Inhibitors, Cytotoxicity, Neurons, Huntingtin Protein, 0303 health sciences, Chemistry, Lymphoblast, S-acylation, Huntington disease, Polyglutamine tract, 3. Good health, Cell biology, ZDHHC17, Neurology, COS Cells, Female, lipids (amino acids, peptides, and proteins), Palmitoylation, RC321-571, congenital, hereditary, and neonatal diseases and abnormalities, Lipoylation, Transgene, Nerve Tissue Proteins, Neurosciences. Biological psychiatry. Neuropsychiatry, Biology, Neuroprotection, Cell Line, 03 medical and health sciences, mental disorders, Animals, Humans, Cysteine, Adaptor Proteins, Signal Transducing, 030304 developmental biology, Acyl-protein thioesterase, Rats, nervous system diseases, nervous system, Mutation, Function (biology), Acyltransferases, 030217 neurology & neurosurgery
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10Academic Journal
المؤلفون: Dekker, Frank J., Hedberg, Christian
المصدر: Dekker , F J & Hedberg , C 2011 , ' Small molecule inhibition of protein depalmitoylation as a new approach towards downregulation of oncogenic Ras signalling ' , Bioorganic & Medicinal Chemistry , vol. 19 , no. 4 , pp. 1376-1380 . https://doi.org/10.1016/j.bmc.2010.11.025
مصطلحات موضوعية: Ras GTPases, Depalmitoylation, Palmostatin B, Acyl protein thioesterase 1 (APT1), Cancer, SIMILARITY CLUSTERING PSSC, NATURAL-PRODUCT STRUCTURE, PLASMA-MEMBRANE, CANCER-THERAPY, H-RAS, PALMITOYLATION, GOLGI, LOCALIZATION, ACYLTRANSFERASES, NANOCLUSTERS
وصف الملف: application/pdf
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11
المؤلفون: Marco Bürger, Stephan A. Sieber, Christian Hedberg, Ingrid R. Vetter, Thomas Böttcher, Andreas Brockmeyer, Kristina Görmer, Frank J. Dekker, Herbert Waldmann, Gemma Triola, Marion Rusch, Tobias J. Zimmermann, Petra Janning
المساهمون: Groningen Research Institute of Pharmacy, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Medicinal Chemistry and Bioanalysis (MCB)
المصدر: Angewandte Chemie-International Edition, 50(42), 9838-9842. WILEY-V C H VERLAG GMBH
Angewandte Chemieمصطلحات موضوعية: BETA-LACTONES, Proteome, Ras proteins, LIPID-MODIFIED PROTEINS, 010402 general chemistry, Proteomics, 01 natural sciences, Catalysis, Structure-Activity Relationship, 03 medical and health sciences, proteomics, CHEMISTRY, Propiolactone, Humans, Sulfones, Enzyme Inhibitors, IN-VIVO, 030304 developmental biology, 0303 health sciences, Molecular Structure, 010405 organic chemistry, Proteomic Profiling, Chemistry, acyl protein thioesterase, LOCALIZATION, General Medicine, General Chemistry, inhibition, 0104 chemical sciences, 3. Good health, DEPALMITOYLATION, Palmitoyl-CoA Hydrolase, Biochemistry, Identification (biology), Acyl-Protein Thioesterase 1, Thiolester Hydrolases, Fatty Acid Synthases, Signal transduction, signal transduction, Palmostatin B, HeLa Cells
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12
المؤلفون: Christian Hedberg, Robin S. Bon, Steffen Renner, Frank J. Dekker, Claas Gerding-Reimers, Philippe I. H. Bastiaens, Stefan Wetzel, Herbert Waldmann, Nachiket Vartak, Marion Rusch
المساهمون: Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD)
المصدر: Angewandte Chemie
Angewandte Chemie-International Edition, 50(42), 9832-9837. WILEY-V C H VERLAG GMBHمصطلحات موضوعية: Models, Molecular, ENZYME, ras protein, Thio, 01 natural sciences, Catalysis, Cell Line, Substrate Specificity, PATHWAY, Lactones, Structure-Activity Relationship, 03 medical and health sciences, Dogs, inhibitors, Animals, Humans, Enzyme Inhibitors, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, NATURAL-PRODUCT STRUCTURE, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, APT1, acyl protein thioesterase, LOCALIZATION, General Medicine, General Chemistry, 0104 chemical sciences, Lysophospholipase I, DEPALMITOYLATION, Enzyme, Biochemistry, Drug Design, PLASMA-MEMBRANE, ras Guanine Nucleotide Exchange Factors, Acyl-Protein Thioesterase 1, Thiolester Hydrolases, Signal transduction, LYSOPHOSPHOLIPASE-I, signal transduction
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13
المؤلفون: Estel, K.
المساهمون: Raunser, Stefan, Musacchio, Andrea
مصطلحات موضوعية: Fluoreszenzmikroskopie, Protein, Mitose, PC 12 Assay, APT, Stopped-Flow, Depalmitoylierung, Acyl protein thioesterase, Ras
وصف الملف: application/pdf
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14
المؤلفون: Vassily Hatzimanikatis, Patrick A. Sandoz, Béatrice Kunz, Laurence Abrami, Georgios Savoglidis, Mustafa Demir, Tiziano Dallavilla, F. Gisou van der Goot
المصدر: eLife, Vol 6 (2017)
eLifeمصطلحات موضوعية: 0301 basic medicine, Mouse, QH301-705.5, Lipoylation, Science, Cell, Endoplasmic-reticulum-associated protein degradation, Models, Biological, General Biochemistry, Genetics and Molecular Biology, src Homology Domains, 03 medical and health sciences, Thioesterase, Palmitoylation, medicine, Humans, palmitoylation, Cysteine, Biology (General), Site-directed mutagenesis, Acyl protein thioesterase, General Immunology and Microbiology, Chemistry, General Neuroscience, Endoplasmic reticulum, turnover, Endoplasmic Reticulum-Associated Degradation, Cell Biology, General Medicine, ERAD, Cell biology, Protein Transport, endoplasmic reticulum, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, Cascade, Proteolysis, Medicine, lipids (amino acids, peptides, and proteins), Thiolester Hydrolases, DHHC, Lipid modification, Acyltransferases, HeLa Cells, Research Article, Human
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15
المؤلفون: Jose L. Daniotti, Javier Valdez Taubas, Maria P. Pedro
المصدر: Traffic (Copenhagen, Denmark). 18(11)
مصطلحات موضوعية: 0301 basic medicine, Otras Ciencias Biológicas, Acylation, Lipoylation, LIPIDATION, Palmitates, Lipid-anchored protein, ACYL-PROTEIN THIOESTERASE, Biology, Biochemistry, PALMITOYLTRANSFERASE, Ciencias Biológicas, 03 medical and health sciences, 0302 clinical medicine, Membrane Microdomains, Palmitoylation, ENDOMEMBRANE TRAFFICKING, Structural Biology, S-ACYLATION, Genetics, Humans, Cysteine, PALMITOYLATION, Molecular Biology, Integral membrane protein, Peripheral membrane protein, Lipid microdomain, S-acylation, Membrane Proteins, Cell Biology, Lipid Metabolism, Cell biology, Transport protein, Protein Transport, 030104 developmental biology, lipids (amino acids, peptides, and proteins), DHHC, Lipid modification, CIENCIAS NATURALES Y EXACTAS, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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16
المؤلفون: Babak Monshi, Martina Sanlorenzo, Rosaura Esteve-Puig, Ryan M. Murphy, Adrian Moy, Andrew Kwong, Aaron Tsumura, Susana Ortiz-Urda, Marin Vujic, Klemens Rappersberger, Christian Posch, Igor Vujic
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Gerontology, Mutant, Blotting, Western, Apoptosis, NRAS, medicine.disease_cause, palmostatin B, GTP Phosphohydrolases, 03 medical and health sciences, 0302 clinical medicine, Palmitoylation, Propiolactone, Tumor Cells, Cultured, melanoma, Medicine, Humans, Molecular Targeted Therapy, Enzyme Inhibitors, RNA, Small Interfering, Cell Proliferation, Mutation, business.industry, Cell growth, Melanoma, APT-1, Membrane Proteins, acyl protein thioesterase, medicine.disease, 3. Good health, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Acyl-Protein Thioesterase 1, Thiolester Hydrolases, business, Palmostatin B, Research Paper
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17Investigation of the properties of Acyl protein thioesterases and their role in Ras depalmitoylation
المؤلفون: Baumeister, Stefan
المساهمون: Winter, Roland, Musacchio, Andrea
مصطلحات موضوعية: Enzym, Protein, Assay development, APT, Structural analysis, Acyl protein thioesterase, Depalmitoylation, Ras
وصف الملف: application/pdf
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18
المؤلفون: Audagnotto, Martina
المساهمون: Dal Peraro, Matteo
مصطلحات موضوعية: Amyloid Precursor Protein (APP), Alzheimerâs disease (AD), molecular modeling, post-translational modifications, biological membrane, Acyl Protein Thioesterase (APT), molecular dynamics, X-ray crystallography, S-acylation
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19
المؤلفون: Sang Joon Won, Brandon T. Ruotolo, Sin Ye Hwang, Fei San Chong, Jaimeen D. Majmudar, Brent R. Martin, Joseph D. Eschweiler
مصطلحات موضوعية: chemistry.chemical_classification, 010405 organic chemistry, Kinase, Metabolite, Organic Chemistry, Activity-based proteomics, Serine hydrolase, Biology, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, ACYL PROTEIN THIOESTERASE 2, chemistry.chemical_compound, Enzyme, chemistry, Drug Discovery, Selectivity, Fluorescence anisotropy
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20
المؤلفون: Takamitsu Sano, Tamotsu Tsukahara, Daniel L. Baker, Yasuyuki Igarashi, Alyssa L. Bolen, Sunitha Yarlagadda, Michael D. Best, Derek D. Norman, Karoly Liliom, Li Chen, Anjaparavanda P. Naren, Gabor Tigyi, Meng M. Rowland, Sarka Beranova-Giorgianni
المصدر: Journal of Lipid Research, Vol 52, Iss 5, Pp 958-970 (2011)
مصطلحات موضوعية: Male, Lysophospholipids, QD415-436, Biology, Biochemistry, Mice, chemistry.chemical_compound, Endocrinology, Phospholipase A1, autotoxin, Lysophosphatidic acid, Animals, Humans, Platelet, Platelet activation, Blood Coagulation, Research Articles, Affinity labeling, Reverse Transcriptase Polymerase Chain Reaction, acyl protein thioesterase, Cell Biology, Platelet Activation, Phospholipases A1, lysophospholipid, chemistry, Lysophospholipase, lipids (amino acids, peptides, and proteins), Autotaxin, lysophosphatidic acid
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