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المؤلفون: Ufuk Erdogdu, Nadezda Dolgikh, Stephanie Laszig, Vinzenz Särchen, Michael T. Meister, Marek Wanior, Stefan Knapp, Cathinka Boedicker
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 109-119 (2022)
Neoplasia (New York, N.Y.)
Neoplasiaمصطلحات موضوعية: BH3 mimetics, PBMC, peripheral blood mononuclear cell, Cancer Research, chemical and pharmacologic phenomena, Antineoplastic Agents, Nerve Tissue Proteins, Receptors, Cell Surface, Apoptosis, PI, propidium iodide, BRD4, bromodomain-containing protein 4, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Biomimetics, hemic and lymphatic diseases, Cell Line, Tumor, Proto-Oncogene Proteins, Rhabdomyosarcoma, BRD, bromodomain, Humans, BET proteins, RC254-282, Original Research, EV, empty vector, zVAD.fmk, N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone, ATCC, American Type Culture Collection, mBCL-2, murine BCL-2, CI, combination index, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, hemic and immune systems, Drug Synergism, BET protein, Bromo- and Extra-Terminal protein, Peptide Fragments, Mitochondria, ERMS, embryonal rhabdomyosarcoma, ARMS, alveolar rhabdomyosarcoma, RMS, rhabdomyosarcoma, FCS, fetal calf serum, biological phenomena, cell phenomena, and immunity
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المؤلفون: Lisa Koodie, Masato Yamamoto, Ryan Shanley, Kari Jacobsen, Praveensingh Hajeri, Mizuho Sato-Dahlman, Hideki Yoshida, Chikako Yanagiba
المصدر: Translational Oncology
Translational Oncology, Vol 14, Iss 2, Pp 100997-(2021)مصطلحات موضوعية: 0301 basic medicine, Oncolytic adenovirus, Cancer Research, Ad5, adenovirus serotype 5, Child cancer, viruses, MRF, Myogenic regulatory factor family, Biology, lcsh:RC254-282, 5/3F, 5/3 fiber (a chimeric fiber containing the Ad5 shaft and Ad3 knob), Fusion gene, 03 medical and health sciences, Transactivation, 0302 clinical medicine, mMEF2, mutation in Myocyte Enhancer Factor-2 binding site, pMYOG, myogenin promoter, medicine, Virotherapy, Rhabdomyosarcoma, Myogenin, Original Research, food and beverages, Fusion-gene, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, musculoskeletal system, OAd, oncolytic adenovirus, 030104 developmental biology, Oncology, Cell culture, 030220 oncology & carcinogenesis, embryonic structures, Cancer research, Alveolar rhabdomyosarcoma, ARMS, alveolar rhabdomyosarcoma, Soft-tissue sarcoma, MEF2, MYOD, myogenic differentiation-1
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المؤلفون: Sheetal A. Mitra, Yong-Hwee Eddie Loh, Zesheng Wan, Xiaogang Hou, Katherine K. Slemmons, Emad Darvishi, Lee J. Helman, Jean Hugues Parmentier
المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 7, Pp 274-282 (2020)مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Jumonji Domain-Containing Histone Demethylases, Original article, DNA Methyltransferase Inhibitor, Down-Regulation, Antineoplastic Agents, DNMTi, DNA methyltransferase inhibitor, lcsh:RC254-282, Pathogenesis, Histones, 03 medical and health sciences, 0302 clinical medicine, Epigenetic marks, Downregulation and upregulation, Cell Line, Tumor, medicine, Humans, Alveolar rhabdomyosarcoma (aRMS), Receptor, Fibroblast Growth Factor, Type 4, Fibroblast growth factor receptor 4 (FGFR4), Rhabdomyosarcoma, Alveolar, Demethylation, Cell Proliferation, FGFR4, fibroblast growth factor receptor 4, biology, Chemistry, Lysine, Histone lysine demethylase 5B (KDM5B), Nuclear Proteins, eRMS, embryonal rhabdomyosarcoma, Fibroblast growth factor receptor 4, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Molecular biology, aRMS, alveolar rhabdomyosarcoma, Chromatin, Repressor Proteins, ChIP-seq, Chromatin immunoprecipitation-sequencing, 030104 developmental biology, Enhancer Elements, Genetic, 030220 oncology & carcinogenesis, Alveolar rhabdomyosarcoma, biology.protein, Azacitidine, Chromatin Immunoprecipitation Sequencing, TSS, transcription start site, Guadecitabine (SGI-110), JARID1B
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المؤلفون: Elisabetta Rossi, Angelica Zin, Paolo Bonvini, Gianni Bisogno, Rita Zamarchi, Luisa Santoro, Lucia Tombolan
المصدر: Translational Oncology, Vol 13, Iss 11, Pp 100846-(2020)
Transl Oncol
Translational Oncologyمصطلحات موضوعية: ES, Ewing sarcoma, 0301 basic medicine, Original article, Cancer Research, Desmoplastic small-round-cell tumor, EMT, epithelial to mesenchymal transition, lcsh:RC254-282, SS, synovial sarcoma, MET, mesenchymal to epithelial transition, 03 medical and health sciences, 0302 clinical medicine, DSRCT, desmoplastic small-round-cell tumor, medicine, IRS, Intergroup Rhabdomyosarcoma Studies (Clinical Group), OS, osteosarcoma, Rhabdomyosarcoma, Bone cancer, business.industry, Cancer, CTCs, circulating tumor cells, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Primary tumor, Synovial sarcoma, ERMS, embryonal rhabdomyosarcoma, STS, soft tissue sarcoma, 030104 developmental biology, EpCAM, epithelial cell adhesion molecule, Oncology, 030220 oncology & carcinogenesis, ARMS, alveolar rhabdomyosarcoma, Cancer research, Osteosarcoma, Sarcoma, Corrigendum, business, IHC, immunohistochemistry
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المؤلفون: Ananya Pal, Reshma Taneja, Hsin Yao Chiu
المصدر: Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biologyمصطلحات موضوعية: Oncology, BIO, 6-bromoindirubin-3′-oxime, FGFR, Fibroblast Growth Factor Receptor, Biochemistry, MCU, Mitochondrial Calcium Uniporter, 0302 clinical medicine, LiCl, Lithium Chloride, Rhabdomyosarcoma, IGF-1R, Insulin-like Growth Factor1 Receptor, Homeostasis, GSI, Gama Secretase Inhibitor, Molecular Targeted Therapy, SOD, Superoxide Dismutase, lcsh:QH301-705.5, PAX3/7-FOXO1, Paired Box Protein 3/7-Forkhead Box Protein O1, TXN, Thioredoxin, Combination chemotherapy, MYF5, Myogenic Factor 5, ARMS, Alveolar Rhabdomyosarcoma, NICD, Notch Intracellular Domain, SHH, Sonic Hedgehog, AKT, Protein Kinase B, SFRP, Secreted Frizzled Related Proteins, PDGF, Platelet Derived Growth Factor, P38MAPK, P38 Mitogen Activated Protein Kinase, SUFU, Suppressor of Fused, BRAF, Proto-oncogene B-Raf and V-Raf Murine Sarcoma Viral Oncogene Homolog B, DDAH1, Dimethylarginine Dimethylaminohydrolase 1, MICU1, Mitochondrial Calcium Uptake 1, RHOA, Ras Homolog Gene Family Member A, lcsh:Medicine (General), TPA, 2-O-tetradecanoylphorbol-13-acetate, Redox homeostasis, medicine.medical_specialty, IGF, Insulin-like Growth Factor, PRC2, Polycomb Repressive Complex 2, Therapeutics, Article, LKB1, Threonine Kinase, PTCH, Patched, WHO, World Health Organization, 03 medical and health sciences, KMT1A, K-methyltransferase 1 A, CSC, Cancer Stem Cell, Humans, ALK, Anaplastic Lymphoma Kinase, DLL1, Delta Like 1, Adverse effect, BCOR, BCL6 Corepressor, HEY1, Hairy and Enhancer of Split Related with YRPW Motif Protein 1, ATP2A3, ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+, medicine.disease, MYOD1, Myoblast Determination Protein, RBPJ, Recombining Binding Protein Suppressor of Hairless, Clinical trial, 030104 developmental biology, HAT, Histone Acetyltransferase, JAG1, Jagged 1, IC, Intracellular, TSA, Trichostatin A, 030217 neurology & neurosurgery, 2-ME, Methoxyestradiol, 0301 basic medicine, VANGL2, Van Gogh-like 2, Clinical Biochemistry, Drug resistance, SMO, Smoothened, Epigenesis, Genetic, VAC, Vincristine, Actinomycin D and Cyclophosphamide, Metastasis, NOSIP, Nitric Oxide Synthase Interacting Protein, COX7A1, Cytochrome c Oxidase Polypeptide 7A1, GLRX, Glutaredoxin, PI3K, Phosphatidylinositol-3-Kinase, TPC, Tumour Propagating Cells, DNMT, DNA Methyltransferase, LRP, Low Density Lipoprotein Receptor Related Protein, GSK3, Glycogen Kinase synthase, GLI, Glioma Associated Oncogene, lcsh:R5-920, VEGF, Vascular Endothelial Growth Factor, EMT, Epithelial to Mesenchymal Transition, FDA, US Food and Drug Administration, Soft tissue sarcoma, CK1α, Caesin Kinase 1 α, PCP, Planar Cell Polarity, HHIP, Hedgehog Interacting Protein, TCF/LEF, Transcription factor/Lymphoid Enhancer Binding Factor 1, SFK, YES/SRC family tyrosine kinase, HIF-1 α, Hypoxia Inducible Factor 1 α, CDK, Cyclin Dependent Kinase, ERK1/2, Extracellular Signal Regulated Kinase ½, JNK, Janus Kinase 1, EGFR, Epithelial Growth Factor Receptor, ICN1, Intracellular Notch Domain 1, Oxidation-Reduction, BRD, BET-containing Proteins, IHH, Indian Hedgehog Protein, Transcription, SP, Specificity Transcription Factor, BET, Bromodomain and extra-terminal, MST1, Macrophage Stimulating 1, TXNDC12, Thioredoxin Domain-containing Protein 12, MEK, Mitogen Activated Protein Kinase, Signalling, EZH2, Enhancer of Zeste Homolog 2, mTOR, (PI3K)-AKT-mammalian target of rapamycin, HES1, Hairy and Enhancer of Split-1, NOS1, Nitric Oxide Synthase 1, Internal medicine, RASSF4, Ras Association domain family member 4, medicine, ERMS, Embryonal Rhabdomyosarcoma, PTK2, Protein Tyrosine Kinase 2, Epigenetics, S6K1, S6 Kinase 1, DZNep, Deazaneplanocin A, MOB1, Mps One Binder Kinase Activator-like 1, SAHA, Suberoylanilide Hydroxamic Acid, DHH, Desert Hedgehog Protein, 5-aza-dc, 5-aza-2′-deoxycytidine, business.industry, GTP, Guanosine-5′-triphosphate, Organic Chemistry, YAP, Yes Associated Protein 1, PPP, Picropodophyllin, PDX, Patient Derived Xenograft, SETD2, SET Domain Containing 2, Oxidative Stress, lcsh:Biology (General), PcG, Polycomb group, AP1, Activator Protein 1, MEF2C, Myocyte Enhancer Factor 2C, SOX2, Sex determining Region Y-box 2, business, ROS, Reactive Oxygen Species
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المؤلفون: Michelle Haber, Glenn M. Marshall, Jennifer A. Byrne, David S. Ziegler, Murray D. Norris, Federica Saletta, Geoffrey McCowage, Carol Wadham
المساهمون: Saletta, Federica, Wadham, Carol, Ziegler, David S, Marshall, Glenn M, Haber, Michelle, McCowage, G, Norris, Murray D, Byrne, Jennifer A
المصدر: BBA Clinical
مصطلحات موضوعية: CAR, chimeric antigen receptor, AURKB, aurora kinase B, PARP, poly(ADP-ribose) polymerase, medicine.medical_treatment, Hsp90, heat shock protein 90, Review, Bioinformatics, Ph +, Philadelphia chromosome-positive, Targeted therapy, SHH, sonic hedgehog, AURKA, aurora kinase A, IGF-1R, insulin-like growth factor type 1 receptor, HDAC, histone deacetylases, Medicine, Profiling (information science), PI3K, phosphatidylinositol 3′-kinase, BET, bromodomain and extra terminal, AML, acute myeloid leukemia, food and beverages, targeted therapy, 3. Good health, PLK1, polo-like kinase 1, AML - Acute myeloid leukemia, Molecular Medicine, RMS, rhabdomyosarcoma, ODC1, ornithine decarboxylase 1, DFMO, difluoromethylornithine, Childhood cancer, mAbs, monoclonal antibodies, mTOR, mammalian target of rapamycin, Pathology and Forensic Medicine, SYK, spleen tyrosine kinase, molecular diagnostics, CML, chronic myeloid leukemia, VEGF/VEGFR, vascular endothelial growth factor/receptor, IGF/IGFR, insulin-like growth factor/receptor, Physiology (medical), NSCLC, non-small cell lung cancer, Molecular diagnostics, childhood cancer, mAb, monoclonal antibody, TRAIL, TNF-related apoptosis-inducing ligand, business.industry, ALK, anaplastic lymphoma kinase, biomarkers, TOP1/TOP2, DNA topoisomerase 1/2, PDGFRA/B, platelet derived growth factor alpha/beta, CAR - Chimeric antigen receptor, ALL, acute lymphoblastic leukemia, EGFR, epidermal growth factor receptor, ERMS, embryonal rhabdomyosarcoma, DIPG, diffuse intrinsic pontine glioma, Non small lung cancer, ARMS, alveolar rhabdomyosarcoma, AT/RT, atypical teratoid/rhabdoid tumor, sense organs, business, ALL - Acute lymphoblastic leukemia, Biomarkers, SMO, smoothened