المؤلفون: Violina T. Angelova, Teodora Tatarova, Rositsa Mihaylova, Nikolay Vassilev, Boris Petrov, Zvetanka Zhivkova, Irini Doytchinova

المصدر: Molecules, Vol 28, Iss 5, p 2058 (2023)

مصطلحات موضوعية: sulfonyl hydrazones, MCF-7, MDA-MB-231, QSAR, breast cancer, anticancer activity, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/5/2058; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/ada11a4569994a539f734932b8dee118

المؤلفون: Irini Doytchinova, Mariyana Atanasova, Iva Valkova, Georgi Stavrakov, Irena Philipova, Zvetanka Zhivkova, Dimitrina Zheleva-Dimitrova, Spiro Konstantinov, Ivan Dimitrov

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 768-776 (2018)

مصطلحات موضوعية: Virtual screening, molecular docking, ITC, PAMPA, Neuro 2A, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/883ef50ce61344b588817af9babb865e

المؤلفون: Boryana Nikolova-Mladenova, Georgi Momekov, Zvetanka Zhivkova, Irini Doytchinova

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 8; Pages: 7352

مصطلحات موضوعية: 4-methoxysalicylaldehyde, hydrazones, SAR, cytotoxic activity, HL-60, KE-37, K-562, BV-173, MCF-7, MDA-MB-231, HEK-293

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms24087352

الاتاحة: https://doi.org/10.3390/ijms24087352

المؤلفون: Teodora Atanasova, Georgi Stavrakov, Stefan Ivanov, Irena Philipova, Dimitrina Zheleva, Atanas Lukarski, Spiro Konstantinov, Irini Doytchinova, Zvetanka Zhivkova, Mariyana Atanasova

المصدر: Molecules
Volume 25
Issue 15
Molecules, Vol 25, Iss 3341, p 3341 (2020)

مصطلحات موضوعية: Pharmaceutical Science, 01 natural sciences, Analytical Chemistry, Mice, chemistry.chemical_compound, Drug Discovery, neurotoxicity, Combinatorial Chemistry Techniques, heterocyclic compounds, ADME, chemistry.chemical_classification, 0303 health sciences, Molecular Structure, Acetylcholinesterase, Molecular Docking Simulation, Biochemistry, Blood-Brain Barrier, Chemistry (miscellaneous), language, Molecular Medicine, medicine.drug, endocrine system, Curcumin, Aché, complex mixtures, Article, Cell Line, lcsh:QD241-441, Structure-Activity Relationship, 03 medical and health sciences, lcsh:Organic chemistry, Alzheimer Disease, Galantamine, medicine, Animals, Humans, BBB permeability, Physical and Theoretical Chemistry, 030304 developmental biology, Amyloid beta-Peptides, Binding Sites, 010405 organic chemistry, organic chemicals, Organic Chemistry, Neurotoxicity, molecular docking, medicine.disease, virtual screening, language.human_language, In vitro, 0104 chemical sciences, Enzyme, chemistry, Cholinesterase Inhibitors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec8aa199f676960d61129b5a2d599017

المؤلفون: Georgi Stavrakov, Dimitrina Zheleva-Dimitrova, Irini Doytchinova, Iva Valkova, Spiro Konstantinov, Irena Philipova, Zvetanka Zhivkova, Ivan Dimitrov, Mariyana Atanasova

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 768-776 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistry

مصطلحات موضوعية: 0301 basic medicine, Virtual screening, Cell Membrane Permeability, Databases, Factual, Drug Evaluation, Preclinical, Small Molecule Libraries, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Neuro 2A, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, lcsh:RM1-950, General Medicine, molecular docking, ITC, Acetylcholinesterase, Blood proteins, In vitro, Molecular Docking Simulation, PAMPA, 030104 developmental biology, Enzyme, lcsh:Therapeutics. Pharmacology, chemistry, Biochemistry, Free fraction, Docking (molecular), Blood-Brain Barrier, Cholinesterase Inhibitors, Acetylcholine, Software, medicine.drug, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165d3d0aa716b532da5144046f1a85a2
https://doaj.org/article/883ef50ce61344b588817af9babb865e

المؤلفون: Zvetanka Zhivkova

المصدر: Journal of Pharmacy & Pharmaceutical Sciences, Vol 20, Iss 1 (2018)

مصطلحات موضوعية: 0301 basic medicine, Drug, Quantitative structure–activity relationship, media_common.quotation_subject, Pharmaceutical Science, lcsh:RS1-441, Datasets as Topic, Quantitative Structure-Activity Relationship, Plasma protein binding, Models, Biological, lcsh:Pharmacy and materia medica, 03 medical and health sciences, Pharmacokinetics, Linear regression, Humans, media_common, Pharmacology, Chromatography, Chemistry, lcsh:RM1-950, Blood Proteins, Stepwise regression, 030104 developmental biology, lcsh:Therapeutics. Pharmacology, Pharmaceutical Preparations, Free fraction, Geometric mean, Algorithms, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c44be89e179ce12469d6d06b577124
https://pubmed.ncbi.nlm.nih.gov/29145933

المؤلفون: Irini Doytchinova, Zvetanka Zhivkova

المصدر: Molecular Pharmaceutics. 10:3758-3768

مصطلحات موضوعية: Drug, Sulfonyl, chemistry.chemical_classification, Quantitative structure–activity relationship, Stereochemistry, Chemistry, Chemical structure, media_common.quotation_subject, Pharmaceutical Science, Plasma protein binding, Models, Theoretical, Blood proteins, Structure-Activity Relationship, Pharmaceutical Preparations, Pharmacokinetics, Drug Discovery, Lipophilicity, Biophysics, Molecular Medicine, Algorithms, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa62ec65f3edfbe0bb1819d12f494823
https://doi.org/10.1021/mp400251k

المؤلفون: Zvetanka Zhivkova, Irini Doytchinova

المصدر: Journal of Pharmaceutical Sciences. 101:4627-4641

مصطلحات موضوعية: Quantitative structure–activity relationship, Chromatography, Databases, Pharmaceutical, Chemistry, Stereochemistry, Quantitative Structure-Activity Relationship, Pharmaceutical Science, Blood Proteins, Plasma protein binding, Models, Biological, Blood proteins, Pharmaceutical Preparations, Pharmacokinetics, Pharmacodynamics, Molecular descriptor, Lipophilicity, Lipinski's rule of five, Humans, Acids, Algorithms, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ce21a19fa0203f8cf3f7349dadb059
https://doi.org/10.1002/jps.23303

المؤلفون: Zvetanka Zhivkova, Irini Doytchinova

المصدر: Journal of Pharmaceutical Sciences. 101:1253-1266

مصطلحات موضوعية: Volume of distribution, Quantitative structure–activity relationship, Chemistry, External validation, Quantitative Structure-Activity Relationship, Pharmaceutical Science, Quantitative structure, Pharmacology, Stepwise regression, Models, Biological, Pharmaceutical Preparations, Pharmacokinetics, Computational chemistry, Molecular descriptor, Humans, Tissue Distribution, Tissue distribution, Acids, Algorithms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d393c92aea2705ed93f8b89f503a232
https://doi.org/10.1002/jps.22819

المؤلفون: Zvetanka Zhivkova, Veska N. Russeva

المصدر: Arzneimittelforschung. 50:272-275

مصطلحات موضوعية: Diazepam binding, Diazepam, Chromatography, Chemistry, Stereochemistry, Binding protein, Anti-Inflammatory Agents, Non-Steroidal, Human serum albumin, Binding, Competitive, High-performance liquid chromatography, Anti-Anxiety Agents, Phenylbutazone, Affinity chromatography, Drug Discovery, Lipophilicity, medicine, Humans, Binding site, Algorithms, Chromatography, High Pressure Liquid, Serum Albumin, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082e9da8c02244e851a7d4c7ac9cb0b7
https://doi.org/10.1055/s-0031-1300198

المؤلفون: Zvetanka Zhivkova

المصدر: International Journal of Pharmacy and Pharmaceutical Sciences. 10:88

مصطلحات موضوعية: Pharmacology, Drug, Chromatography, Chemistry, media_common.quotation_subject, Pharmaceutical Science, Plasma protein binding, Human serum albumin, Pharmacokinetics, Molecular descriptor, Pharmacodynamics, Linear regression, Lipophilicity, medicine, media_common, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::32cb5f1170047911b141a2b49027bce9
https://doi.org/10.22159/ijpps.2018v10i4.24612

المؤلفون: Zvetanka Zhivkova, Irini Doytchinova, Tsvetelina Mandova

المصدر: Scopus-Elsevier
Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 3 (2015)

مصطلحات موضوعية: Volume of distribution, Pharmacology, Quantitative structure–activity relationship, Databases, Factual, lcsh:RM1-950, Quantitative structure, Pharmaceutical Science, lcsh:RS1-441, Quantitative Structure-Activity Relationship, Feature selection, Stepwise regression, Models, Theoretical, computer.software_genre, lcsh:Pharmacy and materia medica, lcsh:Therapeutics. Pharmacology, Pharmacokinetics, Pharmaceutical Preparations, Statistics, Linear regression, Fraction (mathematics), Tissue Distribution, Data mining, computer, Mathematics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8404f18bce93964466c605d0aaceff96
https://pubmed.ncbi.nlm.nih.gov/26517139

المؤلفون: Zvetanka Zhivkova

المصدر: Current pharmaceutical design. 21(14)

مصطلحات موضوعية: Drug, media_common.quotation_subject, Plasma protein binding, Pharmacology, Crystallography, X-Ray, Protein Structure, Secondary, Pharmacokinetics, Drug Discovery, medicine, Animals, Humans, Binding site, Serum Albumin, media_common, Chemistry, Human serum albumin, Blood proteins, body regions, Biochemistry, Pharmaceutical Preparations, Pharmacodynamics, embryonic structures, Drug delivery, medicine.drug, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e1d602fe27e755b4d6a02806469b7f
https://pubmed.ncbi.nlm.nih.gov/25732557

المؤلفون: Zvetanka Zhivkova

المصدر: Journal of Pharmacy & Pharmaceutical Sciences, Vol 20 (2017)

مصطلحات موضوعية: 0301 basic medicine, Quantitative Structure-Activity Relationship, lcsh:RS1-441, Pharmaceutical Science, Plasma protein binding, Pharmacology, 030226 pharmacology & pharmacy, lcsh:Pharmacy and materia medica, Excretion, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Molecular Structure, CYP3A4, Chemistry, lcsh:RM1-950, Stepwise regression, lcsh:Therapeutics. Pharmacology, 030104 developmental biology, Pharmaceutical Preparations, Drug development, Biochemistry, Renal physiology, Lipophilicity, Linear Models, Algorithms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881e051e8dd5d912a0f388ce69dedda8
https://doi.org/10.18433/j3mg71

المؤلفون: Veska N. Russeva, Zvetanka Zhivkova

المصدر: International Journal of Pharmaceutics. 180:69-74

مصطلحات موضوعية: Diclofenac, Chromatography, biology, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Indomethacin, Serum albumin, Pharmaceutical Science, Diclofenac Sodium, Plasma protein binding, Human serum albumin, Binding, Competitive, High-performance liquid chromatography, Sulindac, Indometacin, Biochemistry, Affinity chromatography, medicine, biology.protein, Binding site, Chromatography, High Pressure Liquid, Serum Albumin, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19733cef842d858ad9fcb2cca8b6025a
https://doi.org/10.1016/s0378-5173(98)00397-4

المؤلفون: Veska N. Russeva, Zvetanka Zhivkova, Krassimira Prodanova, Rositza Rakovska

المصدر: Journal of Pharmacy and Pharmacology. 51:49-52

مصطلحات موضوعية: Pharmacology, Circular dichroism, Binding Sites, Diazepam, Chromatography, Chemistry, Circular Dichroism, Pharmaceutical Science, Plasma protein binding, In Vitro Techniques, Piroxicam, Phenylbutazone, Affinity chromatography, medicine, Humans, Titration, Binding site, Quantitative analysis (chemistry), Chromatography, High Pressure Liquid, Serum Albumin, Cotton effect, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6001c4cf4e4e8f0b7463eea35ee35b
https://doi.org/10.1211/0022357991772088

المؤلفون: Veska N. Russeva, Zvetanka Zhivkova

المصدر: Journal of Chromatography B: Biomedical Sciences and Applications. 714:277-283

مصطلحات موضوعية: Chromatography, biology, Elution, Stereochemistry, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Serum albumin, Stereoisomerism, General Chemistry, Reference Standards, Human serum albumin, High-performance liquid chromatography, Chromatography, Affinity, Affinity chromatography, Ketoprofen, biology.protein, medicine, Humans, Stereoselectivity, Enantiomer, Binding site, Chromatography, High Pressure Liquid, Serum Albumin, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b5e879da19f90a51bca885bf7a5839
https://doi.org/10.1016/s0378-4347(98)00211-4

المؤلفون: Zvetanka Zhivkova, Veska N. Russeva

المصدر: International Journal of Pharmaceutics. 168:23-29

مصطلحات موضوعية: Analyte, Chromatography, biology, Chemistry, Albumin, Serum albumin, Pharmaceutical Science, Human serum albumin, High-performance liquid chromatography, Biochemistry, Affinity chromatography, Phenylbutazone, medicine, biology.protein, Binding site, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0c72f63dd07f9ceab28dea3faa05b934
https://doi.org/10.1016/s0378-5173(98)00084-2

المؤلفون: Veska N. Russeva, Zvetanka Zhivkova

المصدر: Arzneimittel-Forschung. 53(3)

مصطلحات موضوعية: Stereochemistry, Binding, Competitive, Hydrophobic effect, Sulindac, Affinity chromatography, Drug Discovery, Phenylbutazone, medicine, Humans, Binding site, Chromatography, High Pressure Liquid, Serum Albumin, Binding Sites, Diazepam, Chemistry, Hydrogen bond, Anti-Inflammatory Agents, Non-Steroidal, Temperature, Human serum albumin, Kinetics, Stationary phase, Thermodynamics, Warfarin, Algorithms, Biomarkers, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7d8e71311d93a6438c0e8bd702a95b
https://pubmed.ncbi.nlm.nih.gov/12705172

المؤلفون: Veska N. Russeva, Zvetanka Zhivkova

المصدر: Arzneimittel-Forschung. 53(1)

مصطلحات موضوعية: Sulindac, Aqueous solution, Chromatography, Hydrogen bond, Chemistry, Enthalpy, Anti-Inflammatory Agents, Non-Steroidal, Temperature, Human serum albumin, Hydrophobic effect, Affinity chromatography, Drug Discovery, medicine, Humans, Thermodynamics, Binding site, Algorithms, Chromatography, High Pressure Liquid, Serum Albumin, medicine.drug, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6a207cf8990a071bb917d526f7b7b7
https://pubmed.ncbi.nlm.nih.gov/12608015