المؤلفون: Wang, Zhaojun¹ (AUTHOR), Su, Xin² (AUTHOR), Shi, Donglei¹ (AUTHOR), Wei, Li¹ (AUTHOR) weili8@mail.sysu.edu.cn

المصدر: BMC Cancer. 12/18/2024, Vol. 24 Issue 1, p1-9. 9p.

مصطلحات موضوعية: *MEDICAL sciences, *ZOLEDRONIC acid, *DIABETES insipidus, *ACID analysis, *BONE metastasis

المؤلفون: Weiqian Wu¹, Wenbiao Zheng¹, Weiwei Pan¹, Fanghu Chen¹, Langqing Jiang¹ jianglangqing@126.com

المصدر: Alternative Therapies in Health & Medicine. Dec2024, Vol. 30 Issue 12, p340-345. 6p.

مصطلحات موضوعية: *KYPHOPLASTY, *ZOLEDRONIC acid, *CHOLECALCIFEROL, *VERTEBRAL fractures, *OSTEOPOROSIS

المؤلفون: Baek, Han-Sang¹ (AUTHOR), shin, Kabsoo² (AUTHOR), Kim, Jinyoung³ (AUTHOR), Jeong, Chaiho¹ (AUTHOR), Lee, Jeongmin⁴ (AUTHOR), Lim, Yejee⁵ (AUTHOR), Baek, Ki-Hyun³ (AUTHOR), Ha, Jeonghoon⁶ (AUTHOR) 3002041@catholic.ac.kr

المصدر: Journal of Bone & Mineral Metabolism. Nov2024, Vol. 42 Issue 6, p720-727. 8p.

مصطلحات موضوعية: *MEDICAL sciences, *ZOLEDRONIC acid, *STERNUM, *BONE resorption, *BIOMARKERS, *LUMBAR vertebrae

المؤلفون: Forman, Daniel E¹ (AUTHOR) formand@pitt.edu, Pignolo, Robert J² (AUTHOR) pignolo.robert@mayo.edu

المصدر: Journals of Gerontology Series A: Biological Sciences & Medical Sciences. Sep2024, Vol. 79 Issue 9, p1-5. 5p.

مصطلحات موضوعية: *OLDER people, *ZOLEDRONIC acid, *DISEASE management, *THERAPEUTICS, *MEDICAL research

المؤلفون: Mohamed, Reham Hussein¹ rehamhussein@med.asu.edu.eg, Abdelrahim, Dina S.^1,2, Hay, Nesma Hussein Abdel³, Fawzy, Nesma Mohamed³, M., Doaa Karem M.⁴, Yehia, Dalia Ahmed Yousef⁴, AbdelMaksoud, Omnia M.⁵, Tamim, Yomna M.¹

المصدر: Scientific Reports. 9/2/2024, Vol. 14 Issue 1, p1-14. 14p.

مصطلحات موضوعية: *RENAL fibrosis, *ZOLEDRONIC acid, *ISOPRENYLATION, *LABORATORY rats, *RATS

المؤلفون: National Institute on Aging (NIA), University of California, San Francisco, Duke University, University of Pittsburgh, Parkinson's Foundation

المصدر: TOPAZ: Trial of Parkinson's and Zoledronic Acid a Randomized Placebo-controlled Trial of Zoledronic Acid for the Prevention of Fractures in Patients with Parkinson's Disease
Tanner CM, Cummings SR, Schwarzschild MA, Brown EG, Dorsey ER, Espay AJ, Galifianakis NB, Goldman SM, Litvan I, Luthra N, McFarland NR, Mitchell KT, Standaert DG, Bauer DC, Greenspan SL, Beck JC, Lyles KW. The TOPAZ study: a home-based trial of zoledronic acid to prevent fractures in neurodegenerative parkinsonism. NPJ Parkinsons Dis. 2021 Mar 1;7(1):16. doi: 10.1038/s41531-021-00162-1.

المؤلفون: Recordati UK

المصدر: Combined Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Metastatic or Inoperable Leiomyosarcoma - DiTuSarc Study

المؤلفون: United States Department of Defense, Aclaris Therapeutics, Inc.

المصدر: A Phase Ib/II Trial of Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

المؤلفون: Lund University Hospital

المساهمون: Erdem Aras Sezgin, Associate Professor

المصدر: Augmentation of Pertrochanteric Fracture Proximal Femoral Nail Osteosynthesis Using Calcium Sulphate/hydroxyapatite Combined with Systemic Bisphosphonate - a Pilot Study of the FARE (Fracture Anchorage and Bone REgeneration) Method
Raina DB, Markeviciute V, Stravinskas M, Kok J, Jacobson I, Liu Y, Sezgin EA, Isaksson H, Zwingenberger S, Tagil M, Tarasevicius S, Lidgren L. A New Augmentation Method for Improved Screw Fixation in Fragile Bone. Front Bioeng Biotechnol. 2022 Mar 2;10:816250. doi: 10.3389/fbioe.2022.816250. eCollection 2022.
Black DM, Delmas PD, Eastell R, Reid IR, Boonen S, Cauley JA, Cosman F, Lakatos P, Leung PC, Man Z, Mautalen C, Mesenbrink P, Hu H, Caminis J, Tong K, Rosario-Jansen T, Krasnow J, Hue TF, Sellmeyer D, Eriksen EF, Cummings SR; HORIZON Pivotal Fracture Trial. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med. 2007 May 3;356(18):1809-22. doi: 10.1056/NEJMoa067312.
Sezgin EA, Tor AT, Markeviciute V, Sirka A, Tarasevicius S, Raina DB, Liu Y, Isaksson H, Tagil M, Lidgren L. A combined fracture and mortality risk index useful for treatment stratification in hip fragility fractures. Jt Dis Relat Surg. 2021;32(3):583-589. doi: 10.52312/jdrs.2021.382. Epub 2021 Nov 19.

المؤلفون: Sheba Medical Center, Rambam Hospital, Haifa, Israel

المساهمون: Hila Elinav, Dr

المصدر: A Single Dose Intravenous Administration of Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive Individuals - a Prospective, Multicenter, Open-label, Randomized Control Trial

المؤلفون: The Claude D. Pepper Older Americans Independence Centers, National Institute on Aging (NIA)

المساهمون: Nami Safai Haeri, Assistant Professor

المصدر: The Impact of Osteoporosis Medications on Muscle Health in Older Adults

المساهمون: Lian Liu, MD, PHD, Professor

المصدر: Efficacy and Safety of Intraperitoneal Immune Checkpoint Inhibitors and Zoledronic Acids in Gastric Cancer Malignant Ascites: a Phase I/II Clinical Study (IPIZA)

المؤلفون: Cancer League of Colorado

المصدر: Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations

المساهمون: Avraam Ploumis, Professor of Phyical and Rehabilitation Medicine

المصدر: Program of Continuous Passive Motion Exercises Against Heterotopic Ossification
Scalzitti DA. Because of the risk of developing heterotopic ossification, are passive range of motion exercises contraindicated following traumatic injuries? Phys Ther. 2003 Jul;83(7):659-7. No abstract available.
Vasileiadis GI, Varvarousis DN, Manolis I, Ploumis A. The Impact of Continuous Passive Motion on Heterotopic Ossification Maturation. Am J Phys Med Rehabil. 2021 Dec 1;100(12):e194-e197. doi: 10.1097/PHM.0000000000001852.
Vasileiadis GI, Balta AA, Zerva A, Kontogiannopoulos V, Varvarousis DN, Dimakopoulos G, Ploumis A. Role of Kinesiotherapy in the Prevention of Heterotopic Ossification: A Systematic Review. Am J Phys Med Rehabil. 2023 Feb 1;102(2):110-119. doi: 10.1097/PHM.0000000000002043. Epub 2022 Apr 28.
Genet F, Chehensse C, Jourdan C, Lautridou C, Denormandie P, Schnitzler A. Impact of the operative delay and the degree of neurologic sequelae on recurrence of excised heterotopic ossification in patients with traumatic brain injury. J Head Trauma Rehabil. 2012 Nov-Dec;27(6):443-8. doi: 10.1097/HTR.0b013e31822b54ba.
van Kampen PJ, Martina JD, Vos PE, Hoedemaekers CW, Hendricks HT. Potential risk factors for developing heterotopic ossification in patients with severe traumatic brain injury. J Head Trauma Rehabil. 2011 Sep-Oct;26(5):384-91. doi: 10.1097/HTR.0b013e3181f78a59.
Citak M, Suero EM, Backhaus M, Aach M, Godry H, Meindl R, Schildhauer TA. Risk factors for heterotopic ossification in patients with spinal cord injury: a case-control study of 264 patients. Spine (Phila Pa 1976). 2012 Nov 1;37(23):1953-7. doi: 10.1097/BRS.0b013e31825ee81b.
Shehab D, Elgazzar AH, Collier BD. Heterotopic ossification. J Nucl Med. 2002 Mar;43(3):346-53.
Holguin PH, Rico AA, Garcia JP, Del Rio JL. Elbow anchylosis due to postburn heterotopic ossification. J Burn Care Rehabil. 1996 Mar-Apr;17(2):150-4. doi: 10.1097/00004630-199603000-00009.
Linan E, O'Dell MW, Pierce JM. Continuous passive motion in the management of heterotopic ossification in a brain injured patient. Am J Phys Med Rehabil. 2001 Aug;80(8):614-7. doi: 10.1097/00002060-200108000-00013.
Stover SL, Hataway CJ, Zeiger HE. Heterotopic ossification in spinal cord-injured patients. Arch Phys Med Rehabil. 1975 May;56(5):199-204.

المؤلفون: Paludetto, Laura Vidoto¹ (AUTHOR) laura.paludetto@unesp.br, Monteiro, Naara Gabriela¹ (AUTHOR) naara.monteiro@unesp.br, Breseghello, Isadora¹ (AUTHOR) isadora.breseghello@unesp.br, de Souza Batista, Fábio Roberto¹ (AUTHOR) fabio.rs.batista@unesp.br, Antoniali, Cristina¹ (AUTHOR) cristina.antoniali@unesp.br, Lisboa-Filho, Paulo Noronha² (AUTHOR) paulo.lisboa@unesp.br, Okamoto, Roberta¹ (AUTHOR) roberta.okamoto@unesp.br

المصدر: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8963. 20p.

مصطلحات موضوعية: *OSTEOPOROSIS in women, *ZOLEDRONIC acid, *BONE resorption, *DENTAL implants, *BONE growth

المؤلفون: Widyadharma, I. Putu Eka¹ eka.widyadharma@unud.ac.id, Tertia, Clarissa², Vania, Aurelia³, Tiffani, Pamela¹, Wiratnaya, I. Gede Eka⁴

المصدر: Postepy Psychiatrii i Neurologii / Advances in Psychiatry & Neurology. 2024, Vol. 33 Issue 3, p172-177. 6p.

مصطلحات موضوعية: *DENOSUMAB, *ZOLEDRONIC acid, *QUALITY of life, *CLINICAL trials

Reviews & Products: GOOGLE Scholar (Web resource)

المؤلفون: EDDC (Experimental Drug Development Centre), A*STAR Research Entities

المصدر: A Phase 1B Investigator Initiated Study to Evaluate the Preliminary Activity, Safety and Tolerability of ETC-159 in Combination with Pembrolizumab in Advanced MSS/pMMR Ovarian Cancers.
Liu J, Pan S, Hsieh MH, Ng N, Sun F, Wang T, Kasibhatla S, Schuller AG, Li AG, Cheng D, Li J, Tompkins C, Pferdekamper A, Steffy A, Cheng J, Kowal C, Phung V, Guo G, Wang Y, Graham MP, Flynn S, Brenner JC, Li C, Villarroel MC, Schultz PG, Wu X, McNamara P, Sellers WR, Petruzzelli L, Boral AL, Seidel HM, McLaughlin ME, Che J, Carey TE, Vanasse G, Harris JL. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20224-9. doi: 10.1073/pnas.1314239110. Epub 2013 Nov 25.
DeVito NC, Sturdivant M, Thievanthiran B, Xiao C, Plebanek MP, Salama AKS, Beasley GM, Holtzhausen A, Novotny-Diermayr V, Strickler JH, Hanks BA. Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy. Cell Rep. 2021 May 4;35(5):109071. doi: 10.1016/j.celrep.2021.109071.

المساهمون: Karen Klahr Miller, MD, Chief, Neuroendocrine Unit, Massachusetts General Hospital

المصدر: Romosozumab As an Adjunct to Physiologic Estrogen Replacement in Adolescents and Young Adults with Functional Hypothalamic Amenorrhea

المؤلفون: University of California, San Francisco, San Francisco VA Health Care System

المساهمون: Elaine W. Yu, Assistant Professor

المصدر: Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery
Tabira T. [Immunological abnormalities in multiple sclerosis]. No To Shinkei. 1983 Jun;35(6):535-41. No abstract available. Japanese.
Ramirez-Lassepas M, Quinones MR. Heparin therapy for stroke: hemorrhagic complications and risk factors for intracerebral hemorrhage. Neurology. 1984 Jan;34(1):114-7. doi: 10.1212/wnl.34.1.114.
Marina Fiol C. [Treatment of the hepatic repercussions of cholelithiasis]. Minerva Med. 1966 Jul 14;57(56):2550-2. No abstract available. Italian.

المصدر: Multicenter, Open-label, Exploratory Phase I Pilot Study to Investigate Safety, Pharmacodynamics, and Pharmacokinetics of Immunological Effects and Activity of Combining Multiple Doses of IMAB362 With Immunomodulation (Zoledronic Acid, Interleukin-2) in Patients With Advanced Adenocarcinoma of the Stomach, the Lower Esophagus, or the Gastroesophageal Junction