المؤلفون: Alan Barnicle, Isabelle Ray-Coquard, Etienne Rouleau, Karen Cadoo, Fiona Simpkins, Carol Aghajanian, Alexandra Leary, Andrés Poveda, Stephanie Lheureux, Eric Pujade-Lauraine, Benoit You, Jonathan Ledermann, Ursula Matulonis, Charlie Gourley, Kirsten M. Timms, Zhongwu Lai, Darren R. Hodgson, Cathy E. Elks, Simon Dearden, Coumaran Egile, Pierre Lao-Sirieix, Elizabeth A. Harrington, Jessica S. Brown

المصدر: Genome Medicine, Vol 16, Iss 1, Pp 1-16 (2024)

مصطلحات موضوعية: Ovarian cancer, Genomic instability, Translational research, Olaparib, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/2cc22ceb55de4044a920709aead2f670

المؤلفون: Gerald J. Sun, Gustavo Arango-Argoty, Gary J. Doherty, Damian E. Bikiel, Dejan Pavlovic, Allen C. Chen, Ross A. Stewart, Zhongwu Lai, Etai Jacob

المصدر: iScience, Vol 27, Iss 9, Pp 110634- (2024)

مصطلحات موضوعية: health sciences, natural sciences, immunity, computer science, Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224018595; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/6446394258df4e7ba96e718b2a6519bd

المؤلفون: Mingchao Xie, Miljenka Vuko, Jaime Rodriguez-Canales, Johannes Zimmermann, Markus Schick, Cathy O’Brien, Luis Paz-Ares, Jonathan W. Goldman, Marina Chiara Garassino, Carl M. Gay, John V. Heymach, Haiyi Jiang, J. Carl Barrett, Ross A. Stewart, Zhongwu Lai, Lauren A. Byers, Charles M. Rudin, Yashaswi Shrestha

المصدر: Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)

مصطلحات موضوعية: Antigen presentation machinery, Biomarkers, CTLA-4, Gene expression profiling, Molecular subtyping, PD-L1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1476-4598

URL الوصول: https://doaj.org/article/dac90161c2bf43f78841723ad0ac6b3b

المؤلفون: Zhongwu Lai, Matthew Brosnan, Ethan S. Sokol, Mingchao Xie, Jonathan R. Dry, Elizabeth A. Harrington, J. Carl Barrett, Darren Hodgson

المصدر: BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)

مصطلحات موضوعية: Homologous recombination deficiency, Homologous recombination repair, Genomic loss of heterozygosity, Loss of function, cancer, Breast, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1471-2407

URL الوصول: https://doaj.org/article/a8395d2b2b2345ee8ea9e874e657f84c

المؤلفون: Miika J. Ahdesmäki, Brad A. Chapman, Pablo Cingolani, Oliver Hofmann, Aleksandr Sidoruk, Zhongwu Lai, Gennadii Zakharov, Mikhail Rodichenko, Mikhail Alperovich, David Jenkins, T. Hedley Carr, Daniel Stetson, Brian Dougherty, J. Carl Barrett, Justin H. Johnson

المصدر: PeerJ, Vol 5, p e3166 (2017)

مصطلحات موضوعية: Structural variation, Gene fusion, Oncology, Prioritisation, Annotation, Visualisation, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://peerj.com/articles/3166.pdf; https://peerj.com/articles/3166/; https://doaj.org/toc/2167-8359

URL الوصول: https://doaj.org/article/c805a6e27ffa47ae840cea70b9209afb

المؤلفون: Miika J. Ahdesmäki, Simon R. Gray, Justin H. Johnson, Zhongwu Lai

المصدر: F1000Research, Vol 5 (2017)

مصطلحات موضوعية: Animal Genetics, Bioinformatics, Medicine, Science

وصف الملف: electronic resource

Relation: https://f1000research.com/articles/5-2741/v2; https://doaj.org/toc/2046-1402

URL الوصول: https://doaj.org/article/f4a08e0f4fb843dd8997442d48b1bf0c

المؤلفون: Miika J. Ahdesmäki, Simon R. Gray, Justin H. Johnson, Zhongwu Lai

المصدر: F1000Research, Vol 5 (2016)

مصطلحات موضوعية: Animal Genetics, Bioinformatics, Medicine, Science

وصف الملف: electronic resource

Relation: https://f1000research.com/articles/5-2741/v1; https://doaj.org/toc/2046-1402

URL الوصول: https://doaj.org/article/077184b7e20b4917957b439d5b9f3dc4

المؤلفون: Luis Paz-Ares, Marina Chiara Garassino, Yuanbin Chen, Niels Reinmuth, Katsuyuki Hotta, Artem Poltoratskiy, Dmytro Trukhin, Maximilian J. Hochmair, Mustafa Özgüroğlu, Jun Ho Ji, Galina Statsenko, Nikolay Conev, Igor Bondarenko, Libor Havel, György Losonczy, Mingchao Xie, Zhongwu Lai, Nadia Godin-Heymann, Helen Mann, Haiyi Jiang, Yashaswi Shrestha, Jonathan W. Goldman

مصطلحات موضوعية: Cancer, Cancer Detection and Diagnosis, Immuno-oncology, Biomarkers, Immunotherapy, Biomarkers for immunotherapy, Checkpoint blockade, Lung Cancer

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Table_S5_from_Durvalumab_Tremelimumab_Platinum-Etoposide_in_Extensive-Stage_Small_Cell_Lung_Cancer_CASPIAN_Outcomes_by_PD-L1_Expression_and_Tissue_Tumor_Mutational_Burden/25232285

الاتاحة: https://doi.org/10.1158/1078-0432.25232285.v1

المؤلفون: Luis Paz-Ares, Marina Chiara Garassino, Yuanbin Chen, Niels Reinmuth, Katsuyuki Hotta, Artem Poltoratskiy, Dmytro Trukhin, Maximilian J. Hochmair, Mustafa Özgüroğlu, Jun Ho Ji, Galina Statsenko, Nikolay Conev, Igor Bondarenko, Libor Havel, György Losonczy, Mingchao Xie, Zhongwu Lai, Nadia Godin-Heymann, Helen Mann, Haiyi Jiang, Yashaswi Shrestha, Jonathan W. Goldman

مصطلحات موضوعية: Cancer, Cancer Detection and Diagnosis, Immuno-oncology, Biomarkers, Immunotherapy, Biomarkers for immunotherapy, Checkpoint blockade, Lung Cancer

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Material_S1_from_Durvalumab_Tremelimumab_Platinum-Etoposide_in_Extensive-Stage_Small_Cell_Lung_Cancer_CASPIAN_Outcomes_by_PD-L1_Expression_and_Tissue_Tumor_Mutational_Burden/25232300

الاتاحة: https://doi.org/10.1158/1078-0432.25232300.v1

المؤلفون: Luis Paz-Ares, Marina Chiara Garassino, Yuanbin Chen, Niels Reinmuth, Katsuyuki Hotta, Artem Poltoratskiy, Dmytro Trukhin, Maximilian J. Hochmair, Mustafa Özgüroğlu, Jun Ho Ji, Galina Statsenko, Nikolay Conev, Igor Bondarenko, Libor Havel, György Losonczy, Mingchao Xie, Zhongwu Lai, Nadia Godin-Heymann, Helen Mann, Haiyi Jiang, Yashaswi Shrestha, Jonathan W. Goldman

مصطلحات موضوعية: Cancer, Cancer Detection and Diagnosis, Immuno-oncology, Biomarkers, Immunotherapy, Biomarkers for immunotherapy, Checkpoint blockade, Lung Cancer

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Figure_S5_from_Durvalumab_Tremelimumab_Platinum-Etoposide_in_Extensive-Stage_Small_Cell_Lung_Cancer_CASPIAN_Outcomes_by_PD-L1_Expression_and_Tissue_Tumor_Mutational_Burden/25232315

الاتاحة: https://doi.org/10.1158/1078-0432.25232315.v1

المؤلفون: Zhongwu Lai (1896406), Matthew Brosnan (11900087), Ethan S. Sokol (8807147), Mingchao Xie (11900090), Jonathan R. Dry (11900093), Elizabeth A. Harrington (11900096), J. Carl Barrett (11900099), Darren Hodgson (11900102)

مصطلحات موضوعية: Genetics, Homologous recombination deficiency, Homologous recombination repair, Genomic loss of heterozygosity, Loss of function, cancer, Breast, Ovarian, Germline, Somatic, PARP inhibitors, Immune checkpoint inhibitors

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Landscape_of_homologous_recombination_deficiencies_in_solid_tumours_analyses_of_two_independent_genomic_datasets/17799647

الاتاحة: https://doi.org/10.6084/m9.figshare.17799647.v1

المؤلفون: T. Hedley Carr, Carrie Adelman, Alan Barnicle, Iwanka Kozarewa, Sally Luke, Zhongwu Lai, Sally Hollis, Brian Dougherty, Elizabeth A. Harrington, Jinyu Kang, Fred Saad, Nuria Sala, Antoine Thiery-Vuillemin, Noel W. Clarke, Darren Hodgson, J. Carl Barrett

المصدر: Cancers; Volume 13; Issue 22; Pages: 5830

مصطلحات موضوعية: circulating tumour DNA (ctDNA), homologous recombination repair (HRR), prostate cancer, next-generation sequencing (NGS), PARP inhibition, metastasis

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers13225830

الاتاحة: https://doi.org/10.3390/cancers13225830

المؤلفون: Matthew G. Krebs, Jean-Pierre Delord, Thomas R. Jeffry Evans, Maja De Jonge, Sang-We Kim, Marie Meurer, Sophie Postel-Vinay, Jong-Seok Lee, Helen K. Angell, Vidalba Rocher-Ros, Kassondra Meyer, Mei-Lin Ah-See, Pia Herbolsheimer, Zhongwu Lai, Ana Nunes, Susan M. Domchek

المساهمون: Medical Oncology

المصدر: Krebs, M G, Delord, J-P, Jeffry Evans, T R, De Jonge, M, Kim, S-W, Meurer, M, Postel-Vinay, S, Lee, J-S, Angell, H K, Rocher-Ros, V, Meyer, K, Ah-See, M-L, Herbolsheimer, P, Lai, Z, Nunes, A & Domchek, S M 2023, ' Olaparib and durvalumab in patients with relapsed small cell lung cancer (MEDIOLA): An open-label, multicenter, phase 1/2, Basket Study ', Lung Cancer, vol. 180, 107216 . https://doi.org/10.1016/j.lungcan.2023.107216
Lung Cancer, 180:107216. Elsevier Ireland Ltd

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Cancer Research, PARP inhibitor, Oncology, SDG 3 - Good Health and Well-being, durvalumab, immunotherapy, small cell lung cancer, olaparib

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f55b6a72887c16967c05c789e2f26d5
https://doi.org/10.1016/j.lungcan.2023.107216

المؤلفون: Kim N. Chi, Alan Barnicle, Caroline Sibilla, Zhongwu Lai, Claire Corcoran, J. Carl Barrett, Carrie A. Adelman, Ping Qiu, Ashley Easter, Simon Dearden, Geoffrey R. Oxnard, Neeraj Agarwal, Arun Azad, Johann de Bono, Joaquin Mateo, David Olmos, Antoine Thiery-Vuillemin, Elizabeth A. Harrington

المساهمون: Institut Català de la Salut, [Chi KN] BC Cancer Agency, Vancouver, Canada. [Barnicle A] Translational Medicine, AstraZeneca, Cambridge, United Kingdom. [Sibilla C, Corcoran C] Precision Medicine and Biosamples, AstraZeneca, Cambridge, United Kingdom. [Lai Z, Barrett JC] Translational Medicine, AstraZeneca, Waltham, Massachusetts. [Mateo J] Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Scientia

مصطلحات موضوعية: Male, BRCA2 Protein, Cancer Research, Pròstata - Càncer, Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::Cell-Free Nucleic Acids::Circulating Tumor DNA [CHEMICALS AND DRUGS], BRCA1 Protein, acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antineoplásicos [COMPUESTOS QUÍMICOS Y DROGAS], Antineoplastic Agents, Ataxia Telangiectasia Mutated Proteins, Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms::Prostatic Neoplasms, Castration-Resistant [DISEASES], Circulating Tumor DNA, Medicaments antineoplàstics, nucleótidos y nucleósidos de ácidos nucleicos::ácidos nucleicos::ácidos nucleicos libres de células::ADN tumoral circulante [COMPUESTOS QUÍMICOS Y DROGAS], Prostatic Neoplasms, Castration-Resistant, Oncology, neoplasias::neoplasias por localización::neoplasias urogenitales::neoplasias de los genitales masculinos::neoplasias de la próstata::neoplasias prostáticas resistentes a la castración [ENFERMEDADES], Mutation, Biomarkers, Tumor, Humans, Cèl·lules canceroses, Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents [CHEMICALS AND DRUGS], Retrospective Studies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050ebcc8565fcfee7b8aae811ea910d3
https://doi.org/10.1158/1078-0432.ccr-22-0931

المؤلفون: Xiao, Jiang, Amanda, O'Neill, Katherine R, Smith, Zhongwu, Lai, Keren, Carss, Quanli, Wang, Slavé, Petrovski

المصدر: Genes, Chromosomes and Cancer. 61:523-529

مصطلحات موضوعية: Cancer Research, Mutation, Missense, Breast Neoplasms, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, United Kingdom, DNA-Binding Proteins, Neoplasms, Genetics, Humans, Exome, Female, Genetic Predisposition to Disease, Biological Specimen Banks

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e23e1262e1d785233efd9b40fe999e5
https://doi.org/10.1002/gcc.23042

المؤلفون: Mark J. O'Connor, Judith Balmaña, Cristina Cruz, Christopher J. Lord, Elaine Cadogan, Josep V. Forment, J. Carl Barrett, Gordon B. Mills, Carlos Caldas, Brian Dougherty, Susan Critchlow, Alan Lau, Cristina Saura, Javier Cortés, Joaquin Arribas, Judit Grueso, Olga Rodríguez, Marta Guzman, Albert Gris-Oliver, Alejandra Bruna, Ambar Ahmed, Paul W.G. Wijnhoven, Adina Hughes, Zena Wilson, Jenni Nikkilä, Krishna C. Bulusu, Stephen J. Pettitt, Aditi Gulati, Rachel Brough, Alba Llop-Guevara, Filippos Michopoulos, Joshua Armenia, Zhongwu Lai, Gemma N. Jones, Andrea Herencia-Ropero, Marta Palafox, Urszula M. Polanska, Marta Castroviejo-Bermejo, Anderson T. Wang, Violeta Serra

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4129939bd7a944921efb38cdb3344eaf
https://doi.org/10.1158/1078-0432.22489313.v1

المؤلفون: Mark J. O'Connor, Judith Balmaña, Cristina Cruz, Christopher J. Lord, Elaine Cadogan, Josep V. Forment, J. Carl Barrett, Gordon B. Mills, Carlos Caldas, Brian Dougherty, Susan Critchlow, Alan Lau, Cristina Saura, Javier Cortés, Joaquin Arribas, Judit Grueso, Olga Rodríguez, Marta Guzman, Albert Gris-Oliver, Alejandra Bruna, Ambar Ahmed, Paul W.G. Wijnhoven, Adina Hughes, Zena Wilson, Jenni Nikkilä, Krishna C. Bulusu, Stephen J. Pettitt, Aditi Gulati, Rachel Brough, Alba Llop-Guevara, Filippos Michopoulos, Joshua Armenia, Zhongwu Lai, Gemma N. Jones, Andrea Herencia-Ropero, Marta Palafox, Urszula M. Polanska, Marta Castroviejo-Bermejo, Anderson T. Wang, Violeta Serra

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddb28e2b040877b2021a52cb106bd7a
https://doi.org/10.1158/1078-0432.22489322

المؤلفون: Elizabeth A. Harrington, Antoine Thiery-Vuillemin, David Olmos, Joaquin Mateo, Johann de Bono, Arun Azad, Neeraj Agarwal, Geoffrey R. Oxnard, Simon Dearden, Ashley Easter, Ping Qiu, Carrie A. Adelman, J. Carl Barrett, Claire Corcoran, Zhongwu Lai, Caroline Sibilla, Alan Barnicle, Kim N. Chi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d5154ea363820d2a4c6b4547cf8579
https://doi.org/10.1158/1078-0432.22489499

المؤلفون: Elizabeth A. Harrington, Antoine Thiery-Vuillemin, David Olmos, Joaquin Mateo, Johann de Bono, Arun Azad, Neeraj Agarwal, Geoffrey R. Oxnard, Simon Dearden, Ashley Easter, Ping Qiu, Carrie A. Adelman, J. Carl Barrett, Claire Corcoran, Zhongwu Lai, Caroline Sibilla, Alan Barnicle, Kim N. Chi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b80c4653e0a112e4f527cdf528960b
https://doi.org/10.1158/1078-0432.22489511.v1

المؤلفون: Elizabeth A. Harrington, Antoine Thiery-Vuillemin, David Olmos, Joaquin Mateo, Johann de Bono, Arun Azad, Neeraj Agarwal, Geoffrey R. Oxnard, Simon Dearden, Ashley Easter, Ping Qiu, Carrie A. Adelman, J. Carl Barrett, Claire Corcoran, Zhongwu Lai, Caroline Sibilla, Alan Barnicle, Kim N. Chi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b6756b0eb67a2c94a85a2c40da3c04
https://doi.org/10.1158/1078-0432.c.6532970.v1