المؤلفون: Qin He, Matthew S. Rehmann, Jun Tian, Jianlin Xu, Luzmary Sabino, Erik Vandermark, Ziev Basson, Iris Po, Kathleen Bierilo, Gabi Tremml, Giovanni Rizzi, Erik F. Langsdorf, Nan-Xin Qian, Michael C. Borys, Anurag Khetan, Zheng-Jian Li

المصدر: Bioengineering, Vol 9, Iss 4, p 173 (2022)

مصطلحات موضوعية: re-cloning, titer, biologics manufacturing, Chinese hamster ovary cells, cell culture platform, Technology, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2306-5354/9/4/173; https://doaj.org/toc/2306-5354

URL الوصول: https://doaj.org/article/9373598c5c5145a395f1797588ed2323

المؤلفون: Emily S. C. Rittershaus, Matthew S. Rehmann, Jianlin Xu, Qin He, Charles Hill, Jeffrey Swanberg, Michael C. Borys, Zheng-Jian Li, Anurag Khetan

المصدر: Bioengineering, Vol 9, Iss 4, p 128 (2022)

مصطلحات موضوعية: perfusion N-1, process intensification, capacitance, process analytical technologies (PAT), cell-specific perfusion rate (CSPR), platform, Technology, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2306-5354/9/4/128; https://doaj.org/toc/2306-5354

URL الوصول: https://doaj.org/article/24c0689bbc314e0d9abca2705b17017e

المؤلفون: Jianlin Xu, Matthew S. Rehmann, Mengmeng Xu, Shun Zheng, Charles Hill, Qin He, Michael C. Borys, Zheng Jian Li

المصدر: Bioresources and Bioprocessing, Vol 7, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Fed-batch platform, Process intensification, Monoclonal antibody manufacturing, Perfusion N-1, Chinese hamster ovary cells, Technology, Chemical technology, TP1-1185, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40643-020-00304-y; https://doaj.org/toc/2197-4365

URL الوصول: https://doaj.org/article/775ee38739c642cc9ba11407c734f826

المؤلفون: Qin He, Jianlin Xu, Erik Vandermark, Jun Tian, Yueming Qian, Cynthia Chelius, Jongchan Lee, Michael C. Borys, Zheng Jian Li, Girish Pendse

المصدر: Data in Brief, Vol 39, Iss , Pp 107491- (2021)

مصطلحات موضوعية: CHO cell culture, High-throughput screening, Rosmarinic acid, Monoclonal antibody titer, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352340921007721; https://doaj.org/toc/2352-3409

URL الوصول: https://doaj.org/article/0d07d6fd26134ab696ee55df8a686e52

المؤلفون: Yuanli Song, Yueming Qian, Zhe Huang, Sarwat F. Khattak, Zheng Jian Li

المصدر: Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3925-3935 (2020)

مصطلحات موضوعية: O-glycosylation, Protein linker, Fc-fusion protein, Sialic acid, Protein aggregation, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037020305043; https://doaj.org/toc/2001-0370

URL الوصول: https://doaj.org/article/95f781049f7d4746ad6e3b0abc5a0ef6

المؤلفون: Tae Keun Kim (10953004), Chiara Botti (10953007), James Angelo (10953010), Xuankuo Xu (4474018), Sanchayita Ghose (4474021), Zheng Jian Li (2838830), Massimo Morbidelli (177667), Mattia Sponchioni (3341864)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Biotechnology, Immunology, Space Science, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, so-designed MCSGP process, process parameters, PEG, batch, Multicolumn Countercurrent Solvent ., purity specification

Relation: https://figshare.com/articles/journal_contribution/Experimental_Design_of_the_Multicolumn_Countercurrent_Solvent_Gradient_Purification_MCSGP_Unit_for_the_Separation_of_PEGylated_Proteins/14762605

الاتاحة: https://doi.org/10.1021/acs.iecr.1c01345.s001

المؤلفون: Steven W. Sowa, Yueming Qian, Kathryn L. Aron, Ping Xu, Erik Langsdorf, Bethanne Warrack, Nelly Aranibar, Gabi Tremml, Jianlin Xu, Duncan McVey, Michael Reily, Anurag Khetan, Michael C. Borys, Zheng Jian Li

المصدر: Data in Brief, Vol 33, Iss , Pp 106591- (2020)

مصطلحات موضوعية: CHO cells, Metabolomics, Cell aging, Genetic instability, Antibody Production, Product quality, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352340920314724; https://doaj.org/toc/2352-3409

URL الوصول: https://doaj.org/article/542fd1b1e063445a8be941eb848a5c5d

المؤلفون: Peifeng Tang, Zhijun Tan, Vivekh Ehamparanathan, Tingwei Ren, Laurel Hoffman, Cheng Du, Yuanli Song, Li Tao, Angela Lewandowski, Sanchayita Ghose, Zheng Jian Li, Shijie Liu

المصدر: mAbs, Vol 12, Iss 1 (2020)

مصطلحات موضوعية: Monoclonal antibody, disulfide bond, redox/reduction/reoxidation, kinetic modeling, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/c3dc9748a0654796b05a080bcd584973

المؤلفون: Zhijun Tan, Vivekh Ehamparanathan, Tingwei Ren, Peifeng Tang, Laurel Hoffman, June Kuang, Peiran Liu, Chao Huang, Cheng Du, Li Tao, Letha Chemmalil, Angela Lewandowski, Sanchayita Ghose, Zheng Jian Li, Shijie Liu

المصدر: mAbs, Vol 12, Iss 1 (2020)

مصطلحات موضوعية: Antibody, disulfide bond, redox/reduction/reoxidation, low molecular weight, Protein A chromatography, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/18ea0b2eb9fc414ebf9fd1ddbcf039cb

المؤلفون: Jianlin Xu, Xuankuo Xu, Chao Huang, James Angelo, Christopher L. Oliveira, Mengmeng Xu, Xia Xu, Deniz Temel, Julia Ding, Sanchayita Ghose, Michael C. Borys, Zheng Jian Li

المصدر: mAbs, Vol 12, Iss 1 (2020)

مصطلحات موضوعية: Process intensification, N-1 perfusion, multi-column chromatography, integrated pool-less polishing, cost of goods, biomanufacturing, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/a3ee1083918640cc8d2da6b5af970e46

المؤلفون: Zhiqiang Chen, Yueming Qian, Yuanli Song, Xuankuo Xu, Li Tao, Nesredin Mussa, Sanchayita Ghose, Zheng Jian Li

المصدر: mAbs, Vol 12, Iss 1 (2020)

مصطلحات موضوعية: therapeutic IgG4, single-point mutation, manufacturability, bioprocessing, bioanalysis, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/4681f5b0243b4abfb5f83706253a71ac

المؤلفون: Peifeng Tang, Jianlin Xu, Christopher L. Oliveira, Zheng Jian Li, Shijie Liu

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 564-571 (2017)

مصطلحات موضوعية: Cancer diagnosis, inhibitor evaluation, kinetic model, lactate dehydrogenase, oligomeric enzyme, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/fb0365afc94b45b781721c720ec883b6

المؤلفون: Zheng‐Jian Li, Ming‐Yang Wang, Chu‐Qiao Li, Wei‐Long Zeng, Wei Li

المصدر: Chemistry – A European Journal.

مصطلحات موضوعية: Organic Chemistry, General Chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b66a47943defaa59ba9c824de941d047
https://doi.org/10.1002/chem.202300776

المؤلفون: Yuanli Song, Hui Cai, Zhijun Tan, Nesredin Mussa, Zheng-Jian Li

المصدر: Applied Microbiology and Biotechnology. 106:1057-1066

مصطلحات موضوعية: Immunoglobulin G, Antibodies, Bispecific, Antibodies, Monoclonal, Humans, Cysteine, Disulfides, General Medicine, Applied Microbiology and Biotechnology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19950ff3820d2fa4d591a727c7e355e1
https://doi.org/10.1007/s00253-022-11778-5

المؤلفون: Zheng Jian Li, Guodong Chen, Li Tao

المصدر: Drug Discovery Today. 27:196-206

مصطلحات موضوعية: Pharmacology, Protein therapeutics, Protein Conformation, Chemistry, Drug Compounding, Deuterium Exchange Measurement, Proteins, Computational biology, Photochemical Processes, Mass spectrometry, Mass Spectrometry, Stability assessment, Characterization (materials science), Structure-Activity Relationship, Epitope mapping, Drug Development, Drug Discovery, Humans, Hydrogen–deuterium exchange, Higher Order Structure

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae999ccb9e706280083492927b01199
https://doi.org/10.1016/j.drudis.2021.09.010

المؤلفون: Tapan K. Das, Nam Ah Kim, Sambit R. Kar, Zheng Jian Li, John F. Carpenter

المصدر: Journal of Pharmaceutical Sciences. 110:3188-3199

مصطلحات موضوعية: Tris, Protein Stability, Antibodies, Monoclonal, Polysorbates, Pharmaceutical Science, 02 engineering and technology, Hydrogen-Ion Concentration, Protein aggregation, 021001 nanoscience & nanotechnology, 030226 pharmacology & pharmacy, Polyvinyl alcohol, Trehalose, 03 medical and health sciences, chemistry.chemical_compound, Colloid, 0302 clinical medicine, chemistry, Biophysics, Virus Inactivation, Particle, Titration, Particle Size, Microparticle, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa6b03342bfcac5d19174ef4d5fd405
https://doi.org/10.1016/j.xphs.2021.06.002

المؤلفون: Li Tao, Zheng Jian Li, Rajesh Singh, Naresh Chennamsetty, Surinder M. Singh, Gurusamy Balakrishnan, Ran Furman

المصدر: Journal of Liquid Chromatography & Related Technologies. 44:265-278

مصطلحات موضوعية: Chromatography, Biopharmaceutical, Mixed-mode chromatography, Chemistry, Clinical Biochemistry, Size-exclusion chromatography, Pharmaceutical Science, Biochemistry, Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::31713b1196759e0719c02f605c707739
https://doi.org/10.1080/10826076.2021.1979582

المؤلفون: Julia Ding, Nesredin Mussa, June Kuang, Yuanqi Tao, Letha Chemmalil, Zheng Jian Li, Yuanli Song

المصدر: Analytical and Bioanalytical Chemistry. 413:2113-2123

مصطلحات موضوعية: Molecular model, Kinetics, Ion chromatography, Succinimides, Peptide, 02 engineering and technology, Peptide Mapping, 01 natural sciences, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, Isomerism, Succinimide, Tandem Mass Spectrometry, Aspartic acid, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Aspartic Acid, Chemistry, 010401 analytical chemistry, Antibodies, Monoclonal, Protein engineering, 021001 nanoscience & nanotechnology, 0104 chemical sciences, Peptides, 0210 nano-technology, Isomerization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e4d27681fa18b6c01ef5f1b149c3e6
https://doi.org/10.1007/s00216-021-03176-z

المؤلفون: Zheng Jian Li, Dhanuka P. Wasalathanthri, Letha Chemmalil, Hasin Feroz, Douglas Both, Gregory Lane, Jessica Hung, Melissa Holstein, Julia Ding, Neha Puri, Sanchayita Ghose

المصدر: Biotechnology and Bioengineering. 117:3766-3774

مصطلحات موضوعية: business.industry, Computer science, Process analytical technology, Ultrafiltration, Antibodies, Monoclonal, Bioengineering, Applied Microbiology and Biotechnology, Unit operation, Diafiltration, symbols.namesake, Data visualization, Fourier transform, Software, Spectroscopy, Fourier Transform Infrared, Partial least squares regression, symbols, business, Process engineering, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698e7ff3bb1a368036c96c9d80bbf4c8
https://doi.org/10.1002/bit.27532

المؤلفون: Jianlin Xu, Johanna Santos, Nadine S. Anderson, Michael C. Borys, Girish Pendse, Zheng Jian Li

المصدر: Biotechnology Progress. 38

مصطلحات موضوعية: Cricetulus, Polysaccharides, Cricetinae, Lysine, Cell Culture Techniques, Animals, Antibodies, Monoclonal, CHO Cells, Carboxypeptidase B, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7651626e0b8645903e811779e9d3c6
https://doi.org/10.1002/btpr.3268