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1Academic Journal
المؤلفون: Deng Chen, Chunlong Zhao, Jianqiu Zhang, Catharina W. J. Knol, Angelina Osipyan, Nad'a Majerníková, Tingting Chen, Zhangping Xiao, Jeaunice Adriana, Andrew J. Griffith, Abel Soto Gamez, Petra E. van derWouden, Robert P. Coppes, Amalia M. Dolga, Hidde J. Haisma, Frank J. Dekker
المصدر: Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
مصطلحات موضوعية: DNA repair, ferroptosis, homologous recombination, inhibitor, macrophage migration inhibitory factor (MIF), Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2198-3844
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2Academic Journal
المؤلفون: Markus Ritzefeld, Leran Zhang, Zhangping Xiao, Sebastian A. Andrei, Olivia Boyd, Naoko Masumoto, Ursula R. Rodgers, Markus Artelsmair, Lea Sefer, Angela Hayes, Efthymios-Spyridon Gavriil, Florence I. Raynaud, Rosemary Burke, Julian Blagg, Henry S. Rzepa, Christian Siebold, Anthony I. Magee, Thomas Lanyon-Hogg, Edward W. Tate
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Pharmacology, Biotechnology, Developmental Biology, Hematology, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, work identifies imp, three key factors, providing tool compounds, inactive control enantiomer, central amide linkage, active chemical probe, several potent analogues, shh signaling pathway, potential drug target, >- terminal palmitoylation, 50 sub, potent cell, r <, n <, c <, μm ic, structural data, secondary amine, results show, inhibitory potency
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3Academic Journal
المؤلفون: Zhangping Xiao (5855825), Angelina Osipyan (5666825), Shanshan Song (500562), Deng Chen (4047067), Reinder A. Schut (11966038), Ronald van Merkerk (3138039), Petra E. van der Wouden (6615692), Robbert H. Cool (2386171), Wim J. Quax (1881640), Barbro N. Melgert (7951046), Gerrit J. Poelarends (1264938), Frank J. Dekker (1514791)
مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Immunology, Developmental Biology, Cancer, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, play key roles, cellular models systems, activated protein kinase, improved antiproliferative activity, 5d b, 50 sub, mif2 tautomerase activity, biological activity, dopachrome tautomerase, h <, targeting mif2, molecules binding, high selectivity, drug target, cell cultures, cancer treatment, >] pyrimidine, >
Time: 3
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4
المؤلفون: Zhangping Xiao, Janine L. Gray, Edward W. Tate
المصدر: Cell Chemical Biology. 30:415-417
مصطلحات موضوعية: Pharmacology, Clinical Biochemistry, Drug Discovery, Molecular Medicine, Molecular Biology, Biochemistry
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5
المؤلفون: Petra E van der Wouden, Zhangping Xiao, Frank J. Dekker, Deng Chen, Dea Gogishvili, Rita Setroikromo, Hao Guo
المساهمون: Chemical and Pharmaceutical Biology, Chemical and Pharmaceutical Biology (GRIP), Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD)
المصدر: Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International ed. in English), 60(40), 21875-21883. WILEY-V C H VERLAG GMBHمصطلحات موضوعية: musculoskeletal diseases, endocrine system diseases, activity-based probes, Molecular Conformation, Context (language use), Activity‐Based Probes | Hot Paper, Catalysis, Lipoxygenase, inhibitors, bromodomains, Arachidonate 15-Lipoxygenase, Humans, Enzyme Inhibitors, Research Articles, biology, integumentary system, Chemistry, Chromatin binding, food and beverages, Lipid metabolism, General Medicine, General Chemistry, lipoxygenases, Bromodomain, Chromatin, oxidoreductases, Histone, Biochemistry, biology.protein, lipids (amino acids, peptides, and proteins), Nuclear localization sequence, Research Article
وصف الملف: application/pdf
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6Academic Journal
المؤلفون: Ya Chen, Xia Yuan, Zhangping Xiao, Hongwei Jin, Liangren Zhang, Zhenming Liu
المصدر: PLoS ONE, Vol 13, Iss 10, p e0205175 (2018)
وصف الملف: electronic resource
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المؤلفون: Zhangping Xiao, Gerrit J. Poelarends, Wim J. Quax, Shanshan Song, Barbro N. Melgert, Frank J. Dekker, Robbert H. Cool, Deng Chen, Ronald van Merkerk, Petra E van der Wouden
المساهمون: Chemical and Pharmaceutical Biology, Molecular Pharmacology, Chemical and Pharmaceutical Biology (GRIP), Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanotechnology and Biophysics in Medicine (NANOBIOMED), Medicinal Chemistry and Bioanalysis (MCB)
المصدر: Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International ed. in English), 60(32), 17514-17521. WILEY-V C H VERLAG GMBHمصطلحات موضوعية: MAPK/ERK pathway, Cell cycle checkpoint, Macrophage migration inhibitory factor (MIF), 01 natural sciences, proteolysis targeting chimera (PROTACs), ACTIVATION, BINDING, A549 cells, Research Articles, Chemistry, General Medicine, respiratory system, Small molecule, Cell biology, G2 Phase Cell Cycle Checkpoints, Intramolecular Oxidoreductases, cell cycle arrest, Cancer Therapy | Hot Paper, medicine.symptom, Research Article, MAP Kinase Signaling System, PROTEINS, Ubiquitin-Protein Ligases, Inflammation, Antineoplastic Agents, Phthalimides, chemical and pharmacologic phenomena, TAUTOMERASE INHIBITORS, 010402 general chemistry, Mitogen-activated protein kinase (MAPK) pathway, Catalysis, PROBES, Spheroids, Cellular, medicine, otorhinolaryngologic diseases, Humans, CYCLE, Macrophage Migration-Inhibitory Factors, Adaptor Proteins, Signal Transducing, Cell Proliferation, A549 cell, COMPLEX, 010405 organic chemistry, POTENT, Proteolysis targeting chimera, Cancer, General Chemistry, medicine.disease, 0104 chemical sciences, Benzoxazines, DISCOVERY, Proteolysis, Macrophage migration inhibitory factor, Drug Screening Assays, Antitumor
وصف الملف: application/pdf
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8
المؤلفون: Zhangping Xiao, Frank J. Dekker, Ali Alipour Najmi, Rainer Bischoff, Hjalmar P. Permentier
المساهمون: Analytical Biochemistry, Chemical and Pharmaceutical Biology, Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD)
المصدر: Green Chemistry, 22(19), 6455-6463. ROYAL SOC CHEMISTRY
مصطلحات موضوعية: Chloroform, DEALKYLATION, Iminium, Tropane, RETICULATED VITREOUS CARBON, TERTIARY, Alkylation, METABOLISM, Pollution, ACTIVATION, chemistry.chemical_compound, EFFICIENT SYNTHESIS, chemistry, Nucleophile, CATALYZED N-DEMETHYLATION/ACYLATION, Yield (chemistry), Oxidizing agent, Environmental Chemistry, Organic chemistry, Methanol, ELECTROORGANIC CHEMISTRY, METHODOLOGY, ANODIC-OXIDATION
وصف الملف: application/pdf
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9
المؤلفون: Zhangping, Xiao, Angelina, Osipyan, Shanshan, Song, Deng, Chen, Reinder A, Schut, Ronald, van Merkerk, Petra E, van der Wouden, Robbert H, Cool, Wim J, Quax, Barbro N, Melgert, Gerrit J, Poelarends, Frank J, Dekker
المصدر: Journal of medicinal chemistry. 65(3)
مصطلحات موضوعية: Binding Sites, Lung Neoplasms, Cell Culture Techniques, Antineoplastic Agents, Cell Cycle Checkpoints, Pyrimidinones, Molecular Dynamics Simulation, Intramolecular Oxidoreductases, Kinetics, Structure-Activity Relationship, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Design, Humans, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Macrophage Migration-Inhibitory Factors, Cell Proliferation
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المؤلفون: Zhangping Xiao, Frank J. Dekker, Shanshan Song, Robbert H. Cool, Fabian Mulder, Deng Chen, Barbro N. Melgert, Petra E van der Wouden, Gerrit J. Poelarends
المساهمون: Chemical and Pharmaceutical Biology (GRIP), Chemical and Pharmaceutical Biology, Molecular Pharmacology, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Groningen Research Institute for Asthma and COPD (GRIAC), Medicinal Chemistry and Bioanalysis (MCB)
المصدر: Chemistry, 28(1):e202103030. Wiley-VCH Verlag GmbH & Co. KGaA
مصطلحات موضوعية: Nuclease, biology, Chemistry, Organic Chemistry, chemical and pharmacologic phenomena, Chromosomal translocation, General Chemistry, biology.organism_classification, Catalysis, Cell biology, Intramolecular Oxidoreductases, HeLa, genomic DNA, medicine.anatomical_structure, Immune system, Cytoplasm, otorhinolaryngologic diseases, medicine, biology.protein, Humans, Macrophage migration inhibitory factor, Macrophage Migration-Inhibitory Factors, Nucleus, HeLa Cells
وصف الملف: application/pdf
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11
المصدر: Cellular and Molecular Life Sciences
مصطلحات موضوعية: Divergent effects, Cell Survival, animal diseases, chemical and pharmacologic phenomena, Review, Binding partners, Signal transduction, Cellular and Molecular Neuroscience, Receptors, otorhinolaryngologic diseases, Homeostasis, Humans, Tissue repair, Molecular Biology, Macrophage Migration-Inhibitory Factors, Pharmacology, Inflammation, Histocompatibility Antigens Class II, Cell Biology, respiratory system, biological factors, Antigens, Differentiation, B-Lymphocyte, Intramolecular Oxidoreductases, Molecular Medicine, Cytokines, Inflammation Mediators, Protein Binding
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12
المؤلفون: Siwei Chen, Frank J. Dekker, Fangyuan Cao, Deng Chen, Hidde J. Haisma, Zhangping Xiao, Chunlong Zhao
المساهمون: Chemical and Pharmaceutical Biology (GRIP), Chemical and Pharmaceutical Biology, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Medicinal Chemistry and Bioanalysis (MCB)
المصدر: Bioorganic Chemistry, 117:105396
مصطلحات موضوعية: Lung Neoplasms, Cell Survival, Antineoplastic Agents, Biochemistry, Histone Deacetylases, Small Molecule Libraries, Carcinoma, Non-Small-Cell Lung, Drug Discovery, medicine, Carcinoma, Humans, Lung cancer, Macrophage Migration-Inhibitory Factors, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Chemistry, Organic Chemistry, Dual inhibitor, respiratory system, medicine.disease, respiratory tract diseases, Histone Deacetylase Inhibitors, Intramolecular Oxidoreductases, A549 Cells, Cancer research, Macrophage migration inhibitory factor, Histone deacetylase, Proto-Oncogene Proteins c-akt, Tyrosine kinase, Signal Transduction
وصف الملف: application/pdf
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13
المؤلفون: Xudong, Sun, Xiaotong, Yu, Yaqi, Zhao, Lei, Xing, Luxin, Na, Zhuo, Chen, Zhangping, Xiao, Hong, Dai, Jing, Yu, Sijie, Long, Quanxin, Wang, Xiaofan, Shi, Zhu, Guan, Ming, Lei, Zhenjun, Yang
المصدر: European Journal of Medicinal Chemistry. 247:115053
مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, General Medicine
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14
المؤلفون: Zhangping Xiao
المساهمون: Dekker, Frank, Quax, W. J., Chemical and Pharmaceutical Biology
مصطلحات موضوعية: Drug discovery, Cancer research, medicine, otorhinolaryngologic diseases, Cancer, Macrophage migration inhibitory factor, Biology, respiratory system, medicine.disease
وصف الملف: application/pdf
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المؤلفون: Frank J. Dekker, Gerrit J. Poelarends, Zhangping Xiao, Shanshan Song, Barbro N. Melgert, Robbert H. Cool, Wim J. Quax, Ronald van Merkerk, Petra E van der Wouden, Deng Chen, Anna K. H. Hirsch, Ramon van der Vlag
المساهمون: Chemical and Pharmaceutical Biology, Molecular Pharmacology, Chemical Biology 2, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Nanotechnology and Biophysics in Medicine (NANOBIOMED), Medicinal Chemistry and Bioanalysis (MCB)
المصدر: Journal of medicinal chemistry
United States
Journal of Medicinal Chemistry, 63(20), 11920-11933. AMER CHEMICAL SOC
Journal of Medicinal Chemistryمصطلحات موضوعية: Models, Molecular, medicine.medical_treatment, animal diseases, INVASION, 01 natural sciences, Assays, Drug Discovery, Imaging probes, Enzyme Inhibitors, chemistry.chemical_classification, 0303 health sciences, Molecular Structure, biology, DERIVATIVES, Chemistry, Biological activity, respiratory system, CANCER, Intramolecular Oxidoreductases, COUMARIN, TARGET, Cytokine, Biochemistry, Molecular Medicine, MIF ENZYMATIC-ACTIVITY, chemical and pharmacologic phenomena, TAUTOMERASE INHIBITORS, Peptides and proteins, Binding, Competitive, Article, Fluorescence, Structure-Activity Relationship, 03 medical and health sciences, medicine, otorhinolaryngologic diseases, Humans, Structure–activity relationship, STRUCTURAL FEATURES, Umbelliferones, Macrophage Migration-Inhibitory Factors, Fluorescent Dyes, 030304 developmental biology, A549 cell, Dose-Response Relationship, Drug, Inhibitors, Active site, Enzyme assay, biological factors, 0104 chemical sciences, CYTOKINE, 010404 medicinal & biomolecular chemistry, Enzyme, DISCOVERY, biology.protein, Macrophage migration inhibitory factor
وصف الملف: application/pdf
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16
المؤلفون: Xiantao Yang, Lihe Zhang, Delin Pan, Chao Wang, Yuan Ma, Zhu Guan, Zhangping Xiao, Yufei Pan, Yiding Li, Shuang Liu, Zhenjun Yang, Wenting Zhao, S.G. Wang, Jing Sun, Yuejie Zhu, Xinyang Zhou, mengyi yang
المساهمون: Drug Design, Chemical and Pharmaceutical Biology
المصدر: Biomaterials, 178, 147-157. ELSEVIER SCI LTD
مصطلحات موضوعية: 0301 basic medicine, RNA Stability, Biophysics, Mice, Nude, Bioengineering, Apoptosis, 02 engineering and technology, Gene delivery, Transfection, Nucleobase, Cell cycle phase, Biomaterials, 03 medical and health sciences, chemistry.chemical_compound, Cell Line, Tumor, Oligonucleotide, DOTA, Animals, Mice, Inbred BALB C, Nucleobase-lipid, Cell Cycle, Hydrogen Bonding, DNA, Self-assembly, Oligonucleotides, Antisense, Plasmid DNA, 021001 nanoscience & nanotechnology, Combinatorial chemistry, Lipids, Thymine, G-Quadruplexes, 030104 developmental biology, chemistry, Mechanics of Materials, Ceramics and Composites, Nucleic acid, Nanoparticles, Female, 0210 nano-technology, Linker, Plasmids
وصف الملف: application/pdf
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17
المؤلفون: Robbert H. Cool, Frank J. Dekker, Zhangping Xiao, Pascal Winkler, Katrin Gruner, Priscila Bourilhon, Markus Brandhofer, Ralph Panstruga, Aphrodite Kapurniotu, Christos Kontos, Jürgen Bernhagen, Dzmitry Sinitski, Anja Reinstädler
المساهمون: Chemical and Pharmaceutical Biology, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Medicinal Chemistry and Bioanalysis (MCB)
المصدر: J Biol Chem
The Journal of Biological Chemistry, 295(3), 850-867. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INCمصطلحات موضوعية: 0301 basic medicine, Chemokine, T-Lymphocytes, Arabidopsis, Sequence Homology, migration, CXCR4, Biochemistry, Monocytes, Chemokine receptor, 0302 clinical medicine, CIRCULAR-DICHROISM SPECTRA, cytokine, CHEMOKINE RECEPTORS, CRYSTAL-STRUCTURE, Receptor, innate immunity, Conserved Sequence, biology, Chemistry, MIF, Chemotaxis, Cell biology, Intramolecular Oxidoreductases, D-DT, 030220 oncology & carcinogenesis, Cytokines, Protein Binding, Receptors, CXCR4, CXCR4 Inhibitor, Immunology, structure?function, chemical and pharmacologic phenomena, 03 medical and health sciences, PROTEIN SECONDARY STRUCTURE, CXC chemokine receptor type 4 (CXCR-4), protein conformation, plant defense, otorhinolaryngologic diseases, Humans, INTERNATIONAL UNION, Molecular Biology, cellular immune response, Macrophage Migration-Inhibitory Factors, Innate immune system, HEK 293 cells, chemokine, D-DOPACHROME TAUTOMERASE, Histocompatibility Antigens Class II, Cell Biology, STRUCTURAL DETERMINANTS, MIGRATION INHIBITORY FACTOR, FACTOR MIF, Immunity, Innate, Antigens, Differentiation, B-Lymphocyte, 030104 developmental biology, HEK293 Cells, inflammation, CD74, biology.protein
وصف الملف: application/pdf
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18Academic Journal
المؤلفون: Zhangping Xiao, Osipyan, Angelina, Song, Shanshan, Deng Chen, Schut, Reinder A., van Merkerk, Ronald, van der Wouden, Petra E., Cool, Robbert H., Quax, Wim J., Melgert, Barbro N., Poelarends, Gerrit J., Dekker, Frank J.
المصدر: Journal of Medicinal Chemistry; 2/10/2022, Vol. 65 Issue 3, p2059-2077, 19p
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19
المؤلفون: Lihe Zhang, Zhiwen Li, Xiantao Yang, Junlin He, Junfei Zhu, Zhenjun Yang, Zhangping Xiao
المصدر: Organic & Biomolecular Chemistry. 14:4032-4038
مصطلحات موضوعية: 010405 organic chemistry, Chemistry, Stereochemistry, Adenine, Organic Chemistry, Deoxyribozyme, DNA, Single-Stranded, Stereoisomerism, DNA, Catalytic, Molecular Dynamics Simulation, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, Nucleobase, Enzyme Activation, Adenine metabolism, Catalytic Domain, Biocatalysis, Thymine metabolism, Physical and Theoretical Chemistry, Enantiomer, Thymine
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المؤلفون: Marieke Fokkens, Gerrit J. Poelarends, Ronald van Merkerk, Giordano Proietti, Frank J. Dekker, Tjie Kok, Deng Chen, Zhangping Xiao
المساهمون: Chemical and Pharmaceutical Biology, Biopharmaceuticals, Discovery, Design and Delivery (BDDD)
المصدر: European Journal of Medicinal Chemistry, 186:111849. ELSEVIER MASSON, CORPORATION OFFICE
مصطلحات موضوعية: medicine.medical_treatment, Microphage migration inhibitory factor (MIF), Triazole-phenols, 01 natural sciences, Cell Movement, Drug Discovery, chemistry.chemical_classification, 0303 health sciences, Molecular Structure, biology, SITE, Transition metals, General Medicine, respiratory system, Molecular Docking Simulation, TARGET, Cytokine, Biochemistry, medicine.symptom, Antibody, Inflammation, TAUTOMERASE INHIBITORS, Structure-Activity Relationship, 03 medical and health sciences, Tautomerase activity, Phenols, otorhinolaryngologic diseases, medicine, Humans, Clonogenic assay, 030304 developmental biology, Pharmacology, A549 cell, Binding Sites, ANALOGS, Dose-Response Relationship, Drug, 010405 organic chemistry, Microscale thermophoresis, Macrophages, Organic Chemistry, Triazoles, 0104 chemical sciences, CYTOKINE, Enzyme, ANTIBODY, chemistry, A549 Cells, NEUTRALIZATION, DISCOVERY, biology.protein, Macrophage migration inhibitory factor
وصف الملف: application/pdf