المؤلفون: Merten, Hannes, Brandl, Fabian, Zimmermann, Martina, Schaefer, Jonas V, Irpinio, Linda, Sand, Kine M K, Nilsen, Jeannette, Andersen, Jan Terje, Zangemeister-Wittke, Uwe, Plückthun, Andreas

المصدر: Merten, Hannes; Brandl, Fabian; Zimmermann, Martina; Schaefer, Jonas V; Irpinio, Linda; Sand, Kine M K; Nilsen, Jeannette; Andersen, Jan Terje; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2021). Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling. European Journal of Pharmaceutics and Biopharmaceutics, 167:104-113.

مصطلحات موضوعية: Department of Biochemistry, 570 Life sciences, biology, 610 Medicine & health

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/210308/1/Merten_at_al_2021.pdf; info:pmid/34303832; urn:issn:0939-6411

الاتاحة: https://www.zora.uzh.ch/id/eprint/210308/
https://www.zora.uzh.ch/id/eprint/210308/1/Merten_at_al_2021.pdf
https://doi.org/10.1016/j.ejpb.2021.07.011

المؤلفون: Zangemeister-Wittke, Uwe, Wels, Winfried

المصدر: Antibodies in Diagnosis and Therapy ; page 81-114 ; ISBN 9781315137513

الاتاحة: http://dx.doi.org/10.1201/9781315137513-3

المؤلفون: Brandl, Fabian, Busslinger, Sarah, Zangemeister-Wittke, Uwe, Plückthun, Andreas

المصدر: Brandl, Fabian; Busslinger, Sarah; Zangemeister-Wittke, Uwe; Plückthun, Andreas (2020). Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life. Journal of Controlled Release, 327:186-197.

مصطلحات موضوعية: Department of Biochemistry, 570 Life sciences, biology, 610 Medicine & health

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/192747/1/Brandl_et_al_2020.pdf; info:pmid/32768630; urn:issn:0168-3659

الاتاحة: https://www.zora.uzh.ch/id/eprint/192747/
https://www.zora.uzh.ch/id/eprint/192747/1/Brandl_et_al_2020.pdf
https://doi.org/10.1016/j.jconrel.2020.08.004

المؤلفون: Schwalm, Stephanie, Erhardt, Martin, Römer, Isolde, Pfeilschifter, Josef, Zangemeister-Wittke, Uwe, Huwiler, Andrea

المصدر: Schwalm, Stephanie; Erhardt, Martin; Römer, Isolde; Pfeilschifter, Josef; Zangemeister-Wittke, Uwe; Huwiler, Andrea (2020). Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt. International journal of molecular sciences, 21(4) Molecular Diversity Preservation International MDPI 10.3390/ijms21041396

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/141735/

الاتاحة: https://boris.unibe.ch/141735/1/Zangemeister_Huwiler_Ceramide%20Kinase%20Is%20Upregulated%20in%20Metastatic%20Breast%20Cancer%20Cells.pdf
https://boris.unibe.ch/141735/

المؤلفون: Lorenzer, Cornelia, Streußnig, Sonja, Tot, Emilia, Winkler, Anna-Maria, Merten, Hannes, Brandl, Fabian, Sayers, Edward J., Watson, Peter, Jones, Arwyn T., Zangemeister-Wittke, Uwe, Plückthun, Andreas, Winkler, Johannes

وصف الملف: application/pdf

Relation: https://orca.cardiff.ac.uk/id/eprint/122646/1/Targeted%20delivery%20and%20endosomal%20cellular%20uptake%20of%20DARPin-siRNA%20bioconjugates-%20Influence%20of%20linker%20stability%20on%20gene%20silencing.pdf; Lorenzer, Cornelia, Streußnig, Sonja, Tot, Emilia, Winkler, Anna-Maria, Merten, Hannes, Brandl, Fabian, Sayers, Edward J. https://orca.cardiff.ac.uk/view/cardiffauthors/A1147882.html orcid:0000-0002-2621-1119 orcid:0000-0002-2621-1119, Watson, Peter https://orca.cardiff.ac.uk/view/cardiffauthors/A108061F.html orcid:0000-0003-0250-7852 orcid:0000-0003-0250-7852, Jones, Arwyn T. https://orca.cardiff.ac.uk/view/cardiffauthors/A009296R.html orcid:0000-0003-2781-8905 orcid:0000-0003-2781-8905, Zangemeister-Wittke, Uwe, Plückthun, Andreas and Winkler, Johannes 2019. Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing. European Journal of Pharmaceutics and Biopharmaceutics 141 , pp. 37-50. 10.1016/j.ejpb.2019.05.015 https://doi.org/10.1016/j.ejpb.2019.05.015 file https://orca.cardiff.ac.uk/id/eprint/122646/1/Targeted%20delivery%20and%20endosomal%20cellular%20uptake%20of%20DARPin-siRNA%20bioconjugates-%20Influence%20of%20linker%20stability%20on%20gene%20silencing.pdf

الاتاحة: https://orca.cardiff.ac.uk/id/eprint/122646/
https://doi.org/10.1016/j.ejpb.2019.05.015
https://orca.cardiff.ac.uk/id/eprint/122646/1/Targeted%20delivery%20and%20endosomal%20cellular%20uptake%20of%20DARPin-siRNA%20bioconjugates-%20Influence%20of%20linker%20stability%20on%20gene%20silencing.pdf

المؤلفون: Blanchard, Olivier, Stepanovska, Bisera, Starck, Manuel, Erhardt, Martin, Römer, Isolde, Meyer zu Heringdorf, Dagmar (Prof. Dr.), Pfeilschifter, Josef, Zangemeister-Wittke, Uwe, Huwiler, Andrea

مصطلحات موضوعية: ddc:610

وصف الملف: application/pdf

Relation: http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46541; urn:nbn:de:hebis:30:3-465410; https://nbn-resolving.org/urn:nbn:de:hebis:30:3-465410; https://doi.org/10.3390/ijms19051498; http://publikationen.ub.uni-frankfurt.de/files/46541/ijms-19-01498.pdf

الاتاحة: http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46541
https://nbn-resolving.org/urn:nbn:de:hebis:30:3-465410
https://doi.org/10.3390/ijms19051498
http://publikationen.ub.uni-frankfurt.de/files/46541/ijms-19-01498.pdf

المؤلفون: Huwiler, Andrea, Zangemeister-Wittke, Uwe

المصدر: Huwiler, Andrea; Zangemeister-Wittke, Uwe (2018). The sphingosine 1-phosphate receptor modulator fingolimod as a therapeutic agent: recent findings and new perspectives. Pharmacology & therapeutics, 185, pp. 34-49. Elsevier 10.1016/j.pharmthera.2017.11.001

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/107169/

الاتاحة: https://boris.unibe.ch/107169/1/Huwiler_Zangemeister_The%20sphingosine.pdf
https://boris.unibe.ch/107169/

المؤلفون: Graumann, Rebecca, Di Capua, Gabriella A, Oyarzún, Juan E, Vásquez, Marcos A, Liao, Christine, Brañes, Jorge A, Roa, Iván, Casanello, Paola, Corvalán, Alejandro H, Owen, Gareth I, Delgado, Iris, Zangemeister-Wittke, Uwe, Ziegler, Annemarie

المصدر: Graumann, Rebecca; Di Capua, Gabriella A; Oyarzún, Juan E; Vásquez, Marcos A; Liao, Christine; Brañes, Jorge A; Roa, Iván; Casanello, Paola; Corvalán, Alejandro H; Owen, Gareth I; Delgado, Iris; Zangemeister-Wittke, Uwe; Ziegler, Annemarie (2017). Expression of teneurins is associated with tumor differentiation and patient survival in ovarian cancer. PLoS ONE, 12(5), e0177244. Public Library of Science 10.1371/journal.pone.0177244

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/100965/

الاتاحة: https://boris.unibe.ch/100965/1/Zangemeister_Expression%20of%20teneurins%20is%20associated%20with%20tumor.pdf
https://boris.unibe.ch/100965/

المؤلفون: Filipenko, Iuliia, Schwalm, Stephanie, Reali, Luca, Pfeilschifter, Josef, Fabbro, Doriano, Huwiler, Andrea, Zangemeister-Wittke, Uwe

المساهمون: Swiss National Science Foundation, German Research Foundation

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ; volume 1861, issue 11, page 1840-1851 ; ISSN 1388-1981

الاتاحة: http://dx.doi.org/10.1016/j.bbalip.2016.09.005
https://api.elsevier.com/content/article/PII:S1388198116302426?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1388198116302426?httpAccept=text/plain

المؤلفون: Schwalm, Stephanie, Maneva Timcheva, Tankica, Filipenko, Iuliia, Ebadi, Mahsa, Hofmann, Lotte P, Zangemeister-Wittke, Uwe, Pfeilschifter, Josef, Huwiler, Andrea

المصدر: Schwalm, Stephanie; Maneva Timcheva, Tankica; Filipenko, Iuliia; Ebadi, Mahsa; Hofmann, Lotte P; Zangemeister-Wittke, Uwe; Pfeilschifter, Josef; Huwiler, Andrea (2015). Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts. Biological chemistry, 396(6-7), pp. 813-825. De Gruyter 10.1515/hsz-2014-0289

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/76763/

الاتاحة: https://boris.unibe.ch/76763/1/Sphingosine%20kinase%202%20deficiency%20increases.pdf
https://boris.unibe.ch/76763/

المؤلفون: Milella, Michele, Trisciuoglio, Daniela, Bruno, Tiziana, Ciuffreda, Ludovica, Mottolese, Marcella, Cianciulli, Anna, Cognetti, Francesco, Zangemeister-Wittke, Uwe, Del Bufalo, Donatella, Zupi, Gabriella

المساهمون: Milella, Michele, Trisciuoglio, Daniela, Bruno, Tiziana, Ciuffreda, Ludovica, Mottolese, Marcella, Cianciulli, Anna, Cognetti, Francesco, Zangemeister-Wittke, Uwe, Del Bufalo, Donatella, Zupi, Gabriella

مصطلحات موضوعية: Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Benzopyrans, Blotting, Western, Breast Neoplasms, Cell Line, Tumor, Enzyme Inhibitors, Flavonoids, Flow Cytometry, Humans, Immunohistochemistry, In Situ Hybridization, Fluorescence, Nitriles, Oligonucleotides, Antisense, Proto-Oncogene Proteins c-bcl-2, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction, Time Factors, Transfection, Trastuzumab, Up-Regulation, bcl-X Protein, Apoptosis

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/15570009; volume:10; issue:22; firstpage:7747; lastpage:7756; numberofpages:10; journal:CLINICAL CANCER RESEARCH; http://hdl.handle.net/11562/1066326

الاتاحة: http://hdl.handle.net/11562/1066326
https://doi.org/10.1158/1078-0432.CCR-04-0908

المؤلفون: Simon, Manuel, Stefan, Nikolas, Borsig, Lubor, Plückthun, Andreas, Zangemeister-Wittke, Uwe

المصدر: Simon, Manuel; Stefan, Nikolas; Borsig, Lubor; Plückthun, Andreas; Zangemeister-Wittke, Uwe (2014). Increasing the antitumor effect of an EpCAM-targeting fusion toxin by facile click PEGylation. Molecular Cancer Therapeutics, 13(2):375-385.

مصطلحات موضوعية: Department of Biochemistry, 570 Life sciences, biology

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/96977/1/Simon_et_al._2014.pdf; https://www.zora.uzh.ch/id/eprint/96977/9/Mol%20Cancer%20Ther-2013-Simon-1535-7163.MCT-13-0523.pdf; info:pmid/24184633; urn:issn:1535-7163

الاتاحة: https://www.zora.uzh.ch/id/eprint/96977/
https://www.zora.uzh.ch/id/eprint/96977/1/Simon_et_al._2014.pdf

المؤلفون: Pastukhov, Oleksandr, Schalm, Stephanie, Römer, Isolde, Pfeilschifter, Josef, Huwiler, Andrea, Zangemeister-Wittke, Uwe

المصدر: Pastukhov, Oleksandr; Schalm, Stephanie; Römer, Isolde; Pfeilschifter, Josef; Huwiler, Andrea; Zangemeister-Wittke, Uwe (2014). Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts. Cellular physiology and biochemistry, 34(1), pp. 119-133. Karger 10.1159/000362989

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/62037/

الاتاحة: https://boris.unibe.ch/62037/1/362989.pdf
https://boris.unibe.ch/62037/

المؤلفون: Pastukhov, Oleksandr, Schwalm, Stephanie, Zangemeister‐Wittke, Uwe, Fabbro, Doriano, Bornancin, Frederic, Japtok, Lukasz, Kleuser, Burkhard, Pfeilschifter, Josef, Huwiler, Andrea

المساهمون: German Research Foundation, Swiss National Science Foundation

المصدر: British Journal of Pharmacology ; volume 171, issue 24, page 5829-5844 ; ISSN 0007-1188 1476-5381

الاتاحة: http://dx.doi.org/10.1111/bph.12886
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fbph.12886
https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/bph.12886

المؤلفون: Pastukhov, Oleksandr, Schwalm, Stephanie, Römer, Isolde, Zangemeister-Wittke, Uwe, Pfeilschifter, Josef, Huwiler, Andrea

المصدر: Cellular Physiology and Biochemistry ; volume 34, issue 1, page 119-133 ; ISSN 1015-8987 1421-9778

الاتاحة: http://dx.doi.org/10.1159/000362989
https://www.karger.com/Article/Pdf/362989

المؤلفون: Brandl, Fabian, Merten, Hannes, Zimmermann, Martina, Béhé, Martin, Zangemeister-Wittke, Uwe, Plückthun, Andreas

المساهمون: University of Zurich, Zangemeister-Wittke, Uwe

مصطلحات موضوعية: 10019 Department of Biochemistry, 3003 Pharmaceutical Science, 570 Life sciences, biology, 610 Medicine & health

وصف الملف: Brandl_et_al_2019.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e1a2afdba6bf81ade5d4f47579c8ec
https://www.zora.uzh.ch/id/eprint/174732/

المؤلفون: Wojtalla, Anna, Fischer, Barbara, Kotelevets, Nataliya, Mauri, Francesco A, Sobek, Jens, Rehrauer, Hubert, Wotzkow, Carlos, Tschan, Mario P, Seckl, Michael J, Zangemeister-Wittke, Uwe, Arcaro, Alexandre

المصدر: Wojtalla, Anna; Fischer, Barbara; Kotelevets, Nataliya; Mauri, Francesco A; Sobek, Jens; Rehrauer, Hubert; Wotzkow, Carlos; Tschan, Mario P; Seckl, Michael J; Zangemeister-Wittke, Uwe; Arcaro, Alexandre (2013). Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. Clinical Cancer Research, 19(1):96-105.

مصطلحات موضوعية: Functional Genomics Center Zurich, 570 Life sciences, biology, 610 Medicine & health

وصف الملف: application/pdf

Relation: https://www.zora.uzh.ch/id/eprint/90538/1/Clin_Cancer_Res-2013-Wojtalla-96-105.pdf; https://www.zora.uzh.ch/id/eprint/90538/4/Clin_Cancer_Res-2012-Wojtalla-1078-0432.CCR-12-1138-1.pdf; info:pmid/23172887; urn:issn:1078-0432

الاتاحة: https://www.zora.uzh.ch/id/eprint/90538/

المؤلفون: Kotelevets, Nataliya, Fabbro, Doriano, Huwiler, Andrea, Zangemeister-Wittke, Uwe

المساهمون: Ahmad, Aamir

المصدر: PLoS ONE ; volume 8, issue 10 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/annotation/cf556c9c-8c18-4d54-b34f-7a2e0c9339e3

المؤلفون: Heine, Markus, Freund, Barbara, Nielsen, Peter, Jung, Caroline, Reimer, Rudolph, Hohenberg, Heinrich, Zangemeister-Wittke, Uwe, Wester, Hans-Juergen, Lüers, Georg H, Schumacher, Udo

المصدر: Heine, Markus; Freund, Barbara; Nielsen, Peter; Jung, Caroline; Reimer, Rudolph; Hohenberg, Heinrich; Zangemeister-Wittke, Uwe; Wester, Hans-Juergen; Lüers, Georg H; Schumacher, Udo (2012). High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes. PLoS ONE, 7(5), e36258. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0036258

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/14099/

الاتاحة: https://boris.unibe.ch/14099/1/fetchObject.pdf
https://boris.unibe.ch/14099/