المؤلفون: Raju Subramanian (1855276), John Ling (15748), Jianhong Wang (225432), Kelly Wang (1834006), Jia Hao (444898), Haolun Jin (1834141), Yurong Lai (1286232), Bernard Murray (3187821), Samantha Wijaya (14293633), Heather Zhang (2471923), Bill J. Smith (9454239)

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Virology, Computational Biology, Chemical Sciences not elsewhere classified, Bictegravir, HIV-1, single-tablet combination regimen, human disposition, nonclinical disposition, radioactivity

Relation: https://figshare.com/articles/journal_contribution/Human_and_Nonclinical_Disposition_of_sup_14_sup_C_Bictegravir_a_Potent_Integrase_Strand-Transfer_Inhibitor_for_the_Treatment_of_HIV-1_Infection/21769633

الاتاحة: https://doi.org/10.6084/m9.figshare.21769633.v2

المؤلفون: Congrong Niu (2232346), Bill Smith (10014344), Yurong Lai (1286232)

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, gene induction, transporters, hepatocytes, constitutive androstane receptor, aryl hydrocarbon receptor

Relation: https://figshare.com/articles/dataset/datasheet1_Transporter_Gene_Regulation_in_Sandwich_Cultured_Human_Hepatocytes_Through_the_Activation_of_Constitutive_Androstane_Receptor_CAR_or_Aryl_Hydrocarbon_Receptor_AhR_pdf/13620662

الاتاحة: https://doi.org/10.3389/fphar.2020.620197.s001

المؤلفون: Donglu Zhang (2102533), Cong Wei (695530), Cornelis E. C. A. Hop (3076098), Matthew R. Wright (3011232), Ming Hu (38573), Yurong Lai (1286232), S. Cyrus Khojasteh (2022331), W. Griff Humphreys (1770196)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Developmental Biology, Marine Biology, Cancer, Inorganic Chemistry, Hematology, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, Pharmacokinetic Behavior, concentration gradients, EER, Underappreciated Mechanisms, drug property, PK parameters, enteroenteric recirculation, Intestinal excretion, molecule drugs, application, RTR mechanisms, Small Molecule Drugs Drug reabsorption

Relation: https://figshare.com/articles/journal_contribution/Intestinal_Excretion_Intestinal_Recirculation_and_Renal_Tubule_Reabsorption_Are_Underappreciated_Mechanisms_That_Drive_the_Distribution_and_Pharmacokinetic_Behavior_of_Small_Molecule_Drugs/14622555

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01720.s001