المؤلفون: Yumiko Okano Tamura, Jun Sugama, Shin‐ichi Abe, Yuji Shimizu, Hideki Hirose, Masanori Watanabe

المصدر: Pharmacology Research & Perspectives, Vol 11, Iss 1, Pp n/a-n/a (2023)

مصطلحات موضوعية: hepatic insulin resistance, somatostatin, SSTR5, type 2 diabetes, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2052-1707

URL الوصول: https://doaj.org/article/d6cbb13994d24064a031fbc4d5c9ef1b

المؤلفون: Hiroaki Yashiro, Shuichi Takagahara, Yumiko Okano Tamura, Ikuo Miyahisa, Junji Matsui, Hideo Suzuki, Shota Ikeda, Masanori Watanabe

المصدر: PLoS ONE, Vol 11, Iss 11, p e0166198 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5104425?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/71e29b2583a04558816e1522b37d1769

المؤلفون: Shinji Iwasaki, Hironobu Yasuno, Derek M. Erion, Yumiko Okano Tamura, Masako Sasaki, Jun Sugama, Kazunobu Aoyama, Hiroaki Yashiro, Masanori Watanabe

المصدر: Journal of Pharmacology and Experimental Therapeutics. 379:280-289

مصطلحات موضوعية: Liver Cirrhosis, Male, medicine.medical_specialty, digestive system, Mice, Liver disease, chemistry.chemical_compound, Non-alcoholic Fatty Liver Disease, Internal medicine, Nonalcoholic fatty liver disease, medicine, Animals, Humans, Enzyme Inhibitors, Mice, Knockout, Pharmacology, Dose-Response Relationship, Drug, Fatty acid metabolism, business.industry, Fatty liver, nutritional and metabolic diseases, Hep G2 Cells, medicine.disease, digestive system diseases, Fatty Liver, Mice, Inbred C57BL, Endocrinology, chemistry, Lipogenesis, Molecular Medicine, Steatosis, Steatohepatitis, Hepatic fibrosis, business, Acetyl-CoA Carboxylase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf495925638a159c985d16b72d4c879
https://doi.org/10.1124/jpet.121.000786

المؤلفون: Yoshihide Nakano, Tsuyoshi Maekawa, Takashi Nakahata, Masanori Watanabe, Shinji Iwasaki, Sachie Morimoto, Asato Kina, Shizuo Kasai, Nobuyuki Takakura, Takeshi Yamasaki, Yuji Shimizu, Yumiko Okano Tamura, Tohru Yamashita, Tomoyuki Odani, Jun Sugama, Hideki Hirose

المصدر: Bioorganic & Medicinal Chemistry. 25:4153-4162

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Clinical Biochemistry, hERG, Pharmaceutical Science, Peptide hormone, Pharmacology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Internal medicine, Drug Discovery, medicine, Humans, Hypoglycemic Agents, Receptors, Somatostatin, Receptor, Molecular Biology, Glucose tolerance test, biology, medicine.diagnostic_test, Chemistry, Somatostatin receptor, Organic Chemistry, Glucose Tolerance Test, Ether-A-Go-Go Potassium Channels, 030104 developmental biology, Endocrinology, Somatostatin, Gene Expression Regulation, Drug Design, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e142ba64317c5da625db4c39b32b21
https://doi.org/10.1016/j.bmc.2017.06.003

المؤلفون: Mitsuaki Imanishi, Shinichi Masada, Ikuo Miyahisa, Kimio Tohyama, Shuichi Takagahara, Tomohiro Andou, Tetsuji Kawamoto, Hiroki Nagase, Ryouta Hayashi, Jun Fujimoto, Rei Okamoto, Nobuyuki Matsunaga, Kazuki Kubo, Koichi Iida, Naoyoshi Noguchi, Yumiko Okano Tamura, Tsuyoshi Maekawa, Ryoma Hara, Junji Matsui

المصدر: Journal of medicinal chemistry. 60(21)

مصطلحات موضوعية: Fatty Acid Desaturases, Intrinsic activity, Stereochemistry, Substituent, Administration, Oral, Biological Availability, 010402 general chemistry, 01 natural sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Delta-5 Fatty Acid Desaturase, In vivo, Drug Discovery, Moiety, Animals, Oxazolidinones, Arachidonic Acid, 010405 organic chemistry, Chemistry, Atherosclerosis, In vitro, 0104 chemical sciences, Bioavailability, Liver, Molecular Medicine, Arachidonic acid, Pharmacophore

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d5ba83c7f16226e7e0a3790fed7e31
https://pubmed.ncbi.nlm.nih.gov/29023121

المؤلفون: Ikuo Miyahisa, Hideo Suzuki, Hiroaki Yashiro, Masanori Watanabe, Shuichi Takagahara, Shota Ikeda, Yumiko Okano Tamura, Junji Matsui

المصدر: PLoS ONE, Vol 11, Iss 11, p e0166198 (2016)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Fatty Acid Desaturases, Leptin, Male, Physiology, medicine.medical_treatment, Adipose tissue, Gene Expression, lcsh:Medicine, 030204 cardiovascular system & hematology, Pathology and Laboratory Medicine, Biochemistry, Fats, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, 8,11,14-Eicosatrienoic Acid, Delta-5 Fatty Acid Desaturase, Medicine and Health Sciences, Insulin, Enzyme Inhibitors, lcsh:Science, Immune Response, Multidisciplinary, Arachidonic Acid, Reverse Transcriptase Polymerase Chain Reaction, Fatty Acids, Hematology, Hep G2 Cells, Lipids, Pyrrolidinones, Body Fluids, Blood, Physiological Parameters, Adipose Tissue, Arachidonic acid, Adiponectin, medicine.symptom, Anatomy, Research Article, medicine.medical_specialty, Immunology, Inflammation, Pyrimidinones, Biology, Bioenergetics, Diet, High-Fat, 03 medical and health sciences, Insulin resistance, Signs and Symptoms, In vivo, Diagnostic Medicine, Internal medicine, Weight Loss, medicine, Animals, Humans, Obesity, Diabetic Endocrinology, Macrophages, Body Weight, lcsh:R, Biology and Life Sciences, medicine.disease, Hormones, Mice, Inbred C57BL, 030104 developmental biology, Biological Tissue, chemistry, lcsh:Q, Insulin Resistance, Energy Metabolism, Diet-induced obese

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d618d893f6365baabdde45a70c3ea3
http://europepmc.org/articles/PMC5104425?pdf=render

المؤلفون: Jun Fujimoto, Rei Okamoto, Naoyoshi Noguchi, Ryoma Hara, Shinichi Masada, Tetsuji Kawamoto, Hiroki Nagase, Yumiko Okano Tamura, Mitsuaki Imanishi, Shuichi Takagahara, Kazuki Kubo, Kimio Tohyama, Koichi Iida, Tomohiro Andou, Ikuo Miyahisa, Junji Matsui, Ryouta Hayashi, Tsuyoshi Maekawa, Nobuyuki Matsunaga

المصدر: Journal of Medicinal Chemistry; 11/9/2017, Vol. 60 Issue 21, p8963-8981, 17p