المؤلفون: Christopher P. Regan, Zhizhen Zeng, David L. Williams, Harold G. Selnick, Rebecca B. White, John F. Fay, Amy Calamari, Cyrille Sur, Stacey O'Malley, Stefanie A. Kane, Samuel Graham, Joseph P. Vacca, Andrew Danziger, Christopher A. Salvatore, Eric L. Moore, Patricia Miller, Maria S. Michener, Nicole T. Pudvah, Steven N. Gallicchio, Jacquelynn J. Cook, Ian M. Bell, Joseph J. Lynch, Yui S. Tang, Chi-Chung Li

المصدر: Journal of Pharmacology and Experimental Therapeutics. 333:152-160

مصطلحات موضوعية: Male, medicine.medical_specialty, Receptors, Peptide, Calcitonin gene-related peptide, Pharmacology, Binding, Competitive, Cell Line, Mice, Radioligand Assay, Calcitonin gene-related peptide receptor antagonist, Calcitonin Gene-Related Peptide Receptor Antagonists, In vivo, Internal medicine, Chlorocebus aethiops, medicine, Animals, Humans, Spiro Compounds, ATP Binding Cassette Transporter, Subfamily B, Member 1, Receptors, Adrenomedullin, Receptor, Chemistry, Antagonist, Brain, Biological Transport, Receptors, Calcitonin, Bridged Bicyclo Compounds, Heterocyclic, Macaca mulatta, Receptors, Islet Amyloid Polypeptide, Vasodilation, Adrenomedullin, Kinetics, Endocrinology, Calcitonin, Autoradiography, Molecular Medicine, Female, Receptors, Calcitonin Gene-Related Peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c73bc77acb2f21270304bf4825ffd2
https://doi.org/10.1124/jpet.109.163816

المؤلفون: Eric L. Moore, Daniel V. Paone, Stefanie A. Kane, Christopher A. Salvatore, Yui S. Tang, Anthony W. Shaw, Christopher S. Burgey

المصدر: European Journal of Pharmacology. 602:250-254

مصطلحات موضوعية: medicine.medical_specialty, Migraine Disorders, GTPgammaS, Neuropeptide, Calcitonin gene-related peptide, Tritium, Binding, Competitive, chemistry.chemical_compound, Calcitonin Gene-Related Peptide Receptor Antagonists, Internal medicine, medicine, Radioligand, Animals, Humans, Receptor, Pharmacology, Telcagepant, business.industry, Imidazoles, Antagonist, Azepines, Macaca mulatta, Adrenomedullin, Kinetics, Endocrinology, chemistry, business, Protein Binding, Receptors, Calcitonin Gene-Related Peptide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2aab8c70f9a655d9f506e34e199406
https://doi.org/10.1016/j.ejphar.2008.11.050

المؤلفون: B.F. Michael, Francisca Vicente, Thomas J. Felcetto, Sang Ho Lee, Mary Motyl, John J. Allocco, Sookhee Ha, Karen Dorso, Lorraine D. Hernandez, José R. Tormo, Chaowei Zhang, Andrew Galgoci, Katherine Young, Dennis M. Schmatz, Jun Wang, Wesley L. Shoop, Fernando Pelaez, Olga Genilloud, John G. Ondeyka, Lawrence F. Colwell, Ken Bartizal, Sheo B. Singh, Ronald E. Painter, Angela Basilio, Richard D. Cummings, Charles Gill, Stephen M. Soisson, Hiranthi Jayasuriya, Lynn L. Silver, John F. Barrett, Srinivas Kodali, Kithsiri Herath, Gopalakrishnan Parthasarathy, Yui S. Tang, Joseph W. Becker, Doris F. Cully, Jeffery D. Hermes

المصدر: Nature. 441:358-361

مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Platensimycin, Antibiotics, Molecular Conformation, Adamantane, Microbial Sensitivity Tests, Biology, Crystallography, X-Ray, medicine.disease_cause, Substrate Specificity, Microbiology, Mice, chemistry.chemical_compound, Antibiotic resistance, Bacterial Proteins, Lipid biosynthesis, 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase, Acetamides, medicine, Animals, Aminobenzoates, Anilides, Oxazolidinones, Multidisciplinary, Linezolid, Pathogenic bacteria, Antimicrobial, Lipids, Streptomyces, Anti-Bacterial Agents, Aminoglycosides, Biochemistry, chemistry, Staphylococcus aureus, Apoproteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9ae088fcefd05c0219a27ebd861336
https://doi.org/10.1038/nature04784

المؤلفون: Charles J. Cohen, Margaret Z Chou, Brande S. Williams, Yui S. Tang, Ivy E. Dick, Brita S. Reiseter, Maria L. Garcia, Gregory J. Kaczorowski, Keith A. Wafford, William J. Martin, Samantha Clark, Vivien A. Warren, Peter T. Meinke, Ge Dai, William H. Parsons, Richard E. Middleton, William A. Schmalhofer, Martin Köhler, McHardy M. Smith, Richard M. Brochu, Shao Pengcheng Patrick, Chou J. Liu, Birgit T. Priest, John P. Felix

المصدر: Biochemistry. 43:9866-9876

مصطلحات موضوعية: Patch-Clamp Techniques, medicine.medical_treatment, Muscle Proteins, Nerve Tissue Proteins, Tetrodotoxin, NAV1.5 Voltage-Gated Sodium Channel, Pharmacology, Biochemistry, Sodium Channels, Cell Line, Mice, Sodium channel blocker, Therapeutic index, Formaldehyde, Ganglia, Spinal, medicine, Animals, Humans, Potency, Patch clamp, Pain Measurement, Analgesics, Binding Sites, NAV1.2 Voltage-Gated Sodium Channel, Chemistry, Sodium channel, Biphenyl Compounds, NAV1.7 Voltage-Gated Sodium Channel, Brain, Succinates, Amides, Recombinant Proteins, Rats, Disease Models, Animal, Anticonvulsant, Neuropathic pain, Sodium Channel Blockers, Synaptosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3ddd47eae5772bd4e88e362138fc4d
https://doi.org/10.1021/bi0493259

المؤلفون: S K Balani, Paul G. Pearson, Alisha R. Miller, Yui S. Tang, Punam Sandhu, Peter J. Bondiskey, Michael L. Morris, Xin Xu

المصدر: Antimicrobial Agents and Chemotherapy. 48:1272-1280

مصطلحات موضوعية: Male, Antifungal Agents, Urinary system, Radioimmunoassay, Urine, Pharmacology, Peptides, Cyclic, Rats, Sprague-Dawley, Excretion, Echinocandins, Lipopeptides, Mice, chemistry.chemical_compound, Species Specificity, Pharmacokinetics, Caspofungin, polycyclic compounds, Animals, Bile, Distribution (pharmacology), Experimental Therapeutics, Pharmacology (medical), Chromatography, High Pressure Liquid, Lagomorpha, biology, Metabolism, biology.organism_classification, Macaca mulatta, Rats, Infectious Diseases, chemistry, Area Under Curve, Female, Rabbits, Peptides, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60732eb9f522f2d6256dab88ec83f42f
https://doi.org/10.1128/aac.48.4.1272-1280.2004

المؤلفون: Sonia Kerrad, Timothy Harrison, Ian Churcher, Susie Williams, Yui S. Tang, Dirk Beher, Earl E. Clarke, José L. Castro, Wensheng Liu, Mark S. Shearman, Huw D. Lewis, Jonathan D.J. Wrigley

المصدر: Journal of Medicinal Chemistry. 46:2275-2278

مصطلحات موضوعية: chemistry.chemical_compound, Butyramide, chemistry, Bicyclic molecule, Stereochemistry, Aryl, Drug Discovery, Lactam, Molecular Medicine, Structure–activity relationship, Hydroxymethyl, Chemical synthesis, Ireland–Claisen rearrangement

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8ace8806549107cc0385af07cda58fb6
https://doi.org/10.1021/jm034058a

المؤلفون: Kathleen M. Rupprecht, John P. Felix, Mary Matyskiela, Yui S. Tang, Gregory J. Kaczorowski, Robert S. Slaughter, Maria L. Garcia, William A. Schmalhofer

المصدر: Biochemistry. 42:4733-4743

مصطلحات موضوعية: Aza Compounds, Saturation binding, Binding Sites, Kv1.3 Potassium Channel, Potassium Channels, Chemistry, Stereochemistry, Allosteric regulation, technology, industry, and agriculture, Cooperative binding, Reversible process, Voltage-gated potassium channel, Binding, Competitive, Biochemistry, Potassium channel, Kinetics, Isomerism, Cyclohexanes, Potassium Channels, Voltage-Gated, Potassium Channel Blockers, lipids (amino acids, peptides, and proteins), Tritium, Receptor, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a73cb79e9ae45004fe42bb2fa1cec4
https://doi.org/10.1021/bi034122q

المؤلفون: Frederick R. Kinder, Ustun B. Sunay, Yui S. Tang

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 31:829-835

مصطلحات موضوعية: Chemistry, Stereochemistry, Organic Chemistry, Ether, Biochemistry, Analytical Chemistry, Catalysis, chemistry.chemical_compound, Furan, Drug Discovery, Hydroxide, Radiology, Nuclear Medicine and imaging, Carbon-14, Tritium, Aliphatic compound, Spectroscopy, Tetrahydrofuran

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::da53121b2461ce3f2e148e8ff7d2b73e
https://doi.org/10.1002/jlcr.2580311013

المؤلفون: Richard M. Brochu, John P. Felix, Yui S. Tang, Birgit T. Priest, Scott B. Hoyt, Joseph L. Duffy, Gregory J. Kaczorowski, William H. Parsons, Kefei Dai, Brande S. Williams, Maria L. Garcia, Clare London

المصدر: Biochemistry. 46(50)

مصطلحات موضوعية: Pharmacology, Biochemistry, Binding, Competitive, Sodium Channels, Cell Line, Membrane Potentials, NAV1.8 Voltage-Gated Sodium Channel, Radioligand Assay, Radioligand, Animals, Humans, Molecular Structure, Chemistry, Sodium channel, HEK 293 cells, Cell Membrane, NAV1.7 Voltage-Gated Sodium Channel, Transfection, Benzazepines, Rats, Electrophysiology, Cell culture, Drug metabolism, Sodium Channel Blockers, Synaptosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a811947ceee6efeef789e03bd8769b4
https://pubmed.ncbi.nlm.nih.gov/18027973

المؤلفون: Thomas A. Baillie, Matthew P. Braun, Wensheng Liu, Wei Tang, Qing Chen, Regina W. Wang, David C. Evans, John R. Strauss, Elaine C. Tung, Yui S. Tang, Varsha Didolkar, George A. Doss, Ralph A. Stearns

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 34(1)

مصطلحات موضوعية: Male, Spectrometry, Mass, Electrospray Ionization, Metabolite, Acyl glucuronidation, Pharmaceutical Science, Tritium, Troleandomycin, chemistry.chemical_compound, In vivo, Zomepirac, medicine, Animals, Humans, Tolmetin, Pharmacology, biology, Cytochrome P450, Glutathione, Metabolism, Rats, chemistry, Biochemistry, Microsome, biology.protein, Hepatocytes, Microsomes, Liver, Female, Oxidation-Reduction, NADP, medicine.drug, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34695291a5bb5ea8c83eb23bdaf5c24
https://pubmed.ncbi.nlm.nih.gov/16251255

المؤلفون: Dennis C. Dean, Margarita Garcia-Calvo, Meredith Hughes, Michael P. Graziano, Diane E. Shevell, Feroze Ujjainwalla, Marsha Smith, Nancy A. Thornberry, JeanMarie Lisnock, Patricia A. Detmers, Kevin T. Chapman, Duane A. Burnett, Herbert G. Bull, Kim O’Neill, James H. Crona, D. Euan MacIntyre, Anthony Ogawa, Scott W. Altmann, Brian E. Hawes, Yui S. Tang, Harry R. Davis, Sai Prasad N Iyer, Amanda M. Makarewicz, Matthew P. Braun

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 102(23)

مصطلحات موضوعية: Brush border, medicine.drug_class, Biology, law.invention, Cell Line, Rats, Sprague-Dawley, chemistry.chemical_compound, Mice, Ezetimibe, Species Specificity, law, medicine, Animals, Humans, Cholesterol absorption inhibitor, Intestinal Mucosa, Niemann-Pick Diseases, Multidisciplinary, Binding Sites, Microvilli, Cholesterol, Ligand binding assay, HEK 293 cells, Cell Membrane, Membrane Proteins, Membrane Transport Proteins, Proteins, Biological Sciences, Macaca mulatta, Rats, Intestines, Mice, Inbred C57BL, Enterocytes, chemistry, Biochemistry, Intestinal cholesterol absorption, Recombinant DNA, Azetidines, medicine.drug, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5aa92e6b9283147b2fca480492e921b
https://pubmed.ncbi.nlm.nih.gov/15928087

المؤلفون: Ian, Churcher, Susie, Williams, Sonia, Kerrad, Timothy, Harrison, José L, Castro, Mark S, Shearman, Huw D, Lewis, Earl E, Clarke, Jonathan D J, Wrigley, Dirk, Beher, Yui S, Tang, Wensheng, Liu

المصدر: Journal of medicinal chemistry. 46(12)

مصطلحات موضوعية: Benzodiazepines, Benzodiazepinones, Structure-Activity Relationship, Amyloid beta-Peptides, Drug Design, Isotope Labeling, Endopeptidases, Tumor Cells, Cultured, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, Amyloid Precursor Protein Secretases, Ligands

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::12eccae3bbbbf4c66a91024b90e2c14e
https://pubmed.ncbi.nlm.nih.gov/12773031

المؤلفون: William K. Hagmann, Wenji Yin, Linus S. Lin, Ashok Chaudhary, Thomas J. Lanza, Yui S. Tang, Ralph A. Stearns, Koppara Samuel, David C. Evans, Sanjeev Kumar, James P. Jewell

المصدر: Journal of mass spectrometry : JMS. 38(2)

مصطلحات موضوعية: Male, Spectrometry, Mass, Electrospray Ionization, Drug discovery, Chemical structure, Metabolite, Reactive intermediate, Glutathione, Drugs, Investigational, Mass spectrometry, Tritium, Rats, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Biochemistry, chemistry, Pharmacokinetics, Microsomes, Liver, Animals, Humans, Ion trap, Spectroscopy, Biotransformation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83540efb60a0e9cf6329f837bab0b08a
https://pubmed.ncbi.nlm.nih.gov/12577288

المؤلفون: Michael J. Forrest, John Kao, Michael H. Fisher, Pasquale P. Vicario, Shuet-Hing Lee Chiu, Jennifer E. Hutchins, Raul F. Alvaro, Ronald C. Newbold, Timothy V Olah, Ann E. Weber, Ralph A. Stearns, Emma R. Parmee, Yui S. Tang, John Szumiloski, D. Euan MacIntyre, Debra McLoughlin, Hyun O. Ok, Matthew J. Wyvratt, Mari R. Candelore, Gary J Hom, Leroy Perkins, Catherine D. Strader, Margaret A. Cascieri, Laurie Tota, Liping Deng, Robert J. Mathvink, Randall R. Miller

المصدر: Bioorganicmedicinal chemistry letters. 8(16)

مصطلحات موضوعية: medicine.medical_specialty, Pyridines, Lipolysis, Clinical Biochemistry, Pharmaceutical Science, Biological Availability, Biochemistry, Partial agonist, Binding, Competitive, Propanolamines, Structure-Activity Relationship, Dogs, Pharmacokinetics, Oral administration, In vivo, Internal medicine, Drug Discovery, Receptors, Adrenergic, beta, medicine, Animals, Humans, Receptor, Molecular Biology, Sulfonamides, biology, Molecular Structure, Chemistry, Organic Chemistry, Fissipedia, Adrenergic beta-Agonists, biology.organism_classification, Macaca mulatta, Bioavailability, Kinetics, Endocrinology, Receptors, Adrenergic, beta-3, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52e5f47eefa66afb40ebad30a08f9ec
https://pubmed.ncbi.nlm.nih.gov/9873496

المؤلفون: Paul G. Pearson, Michael L. Morris, Yui S. Tang, Alisha R. Miller, Punam S, Xin Xu, Peter J. Bondiskey, Suresh K

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://aac.asm.org/content/48/4/1272.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.621.7809; http://aac.asm.org/content/48/4/1272.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.621.7809
http://aac.asm.org/content/48/4/1272.full.pdf

المؤلفون: Priest, Birgit T., Garcia, Maria L., Middleton, Richard E., Brochu, Richard M., Clark, Samantha, Ge Dai, Dick, Ivy E., Felix, John P., Chou J. Liu, Reiseter, Brita S., Schmalhofer, William A., Shao, Pengcheng P., Yui S. Tang, Margaret Z. Chou, Kohler, Martin G., Smith, McHardy M., Warren, Vivien A., Williams, Brande S., Cohen, Charles J., Martin, William J.

المصدر: Biochemistry; 8/3/2004, Vol. 43 Issue 30, p9866-9876, 11p

المؤلفون: Yui S Tang, Ann-Marie Davis, J. Philip Kitcher

المصدر: Journal of Labelled Compounds and Radiopharmaceuticals. 20:277-284

مصطلحات موضوعية: chemistry.chemical_classification, Chromatography, Organic Chemistry, Lysine, Biochemistry, Wheat germ agglutinin, Analytical Chemistry, Reaction rate, Hydrolysis, chemistry, Labelling, Reagent, Drug Discovery, Propionate, Radiology, Nuclear Medicine and imaging, Tritium, Spectroscopy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7e4ffa57cdd57bba441a54c59c57fdc4
https://doi.org/10.1002/jlcr.2580200214

المؤلفون: Yui S. Tang, Mervyn A. Long, John R. Jones, Leonor Carroll

المصدر: Journal of Chromatography A. 287:381-384

مصطلحات موضوعية: SIMPLE (dark matter experiment), Chromatography, Chemistry, Instrumentation, Organic Chemistry, General Medicine, Biochemistry, Analytical Chemistry, law.invention, law, Ionization chamber, Flame ionization detector, Tritium, Radiochemical analysis, Gas chromatography

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::52f03f7accc6aa49c216a08fe9952cb0
https://doi.org/10.1016/s0021-9673(01)87714-1