المؤلفون: Daniel Aird, Teng Teng, Chia-Ling Huang, Ermira Pazolli, Deepti Banka, Kahlin Cheung-Ong, Cheryl Eifert, Craig Furman, Zhenhua Jeremy Wu, Michael Seiler, Silvia Buonamici, Peter Fekkes, Craig Karr, James Palacino, Eunice Park, Peter G. Smith, Lihua Yu, Yoshiharu Mizui, Markus Warmuth, Agustin Chicas, Laura Corson, Ping Zhu

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/3d3b4213a3e7400997cdfc63d11b14e8

المؤلفون: Teng Teng, Jennifer HC Tsai, Xiaoling Puyang, Michael Seiler, Shouyong Peng, Sudeep Prajapati, Daniel Aird, Silvia Buonamici, Benjamin Caleb, Betty Chan, Laura Corson, Jacob Feala, Peter Fekkes, Baudouin Gerard, Craig Karr, Manav Korpal, Xiang Liu, Jason T. Lowe, Yoshiharu Mizui, James Palacino, Eunice Park, Peter G. Smith, Vanitha Subramanian, Zhenhua Jeremy Wu, Jian Zou, Lihua Yu, Agustin Chicas, Markus Warmuth, Nicholas Larsen, Ping Zhu

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/bcd02552d59140f1871d75acbfffec14

المؤلفون: Rachel B. Darman, Michael Seiler, Anant A. Agrawal, Kian H. Lim, Shouyong Peng, Daniel Aird, Suzanna L. Bailey, Erica B. Bhavsar, Betty Chan, Simona Colla, Laura Corson, Jacob Feala, Peter Fekkes, Kana Ichikawa, Gregg F. Keaney, Linda Lee, Pavan Kumar, Kaiko Kunii, Crystal MacKenzie, Mark Matijevic, Yoshiharu Mizui, Khin Myint, Eun Sun Park, Xiaoling Puyang, Anand Selvaraj, Michael P. Thomas, Jennifer Tsai, John Y. Wang, Markus Warmuth, Hui Yang, Ping Zhu, Guillermo Garcia-Manero, Richard R. Furman, Lihua Yu, Peter G. Smith, Silvia Buonamici

المصدر: Cell Reports, Vol 13, Iss 5, Pp 1033-1045 (2015)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124715010785; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/ff6c0ceb5e1f4d5b93d3d3ccbbf6a31c

المؤلفون: Daisuke Itoh, Jun Niijima, Makoto Asada, Masao Iwata, Mitsuo Nagai, Naoki Asai, Regina M. Kanada, Shinya Abe, Yoshiharu Mizui, Yoshihiko Kotake, 伊藤 大輔, 小竹 良彦, 岩田 正夫, 新島 淳, 水井 佳治, 永井 光雄, 浅井 直樹, 浅田 誠, 阿部 信也

المصدر: Symposium on the Chemistry of Natural Products, symposium papers. 2007, :193

المؤلفون: HAJIME SHIMIZU, KENTARO YOSHIMATSU, KIYOSHI OKAMOTO, MAKOTO ASADA, MASAO IWATA, TAKAO YAMORI, TAKASHI SAKAI, TOSHIMITSU UENAKA, YOSHIHARU MIZUI

المصدر: The Journal of Antibiotics. 2004, 57(3):188

المؤلفون: KAZUYUKI DOBASHI, MOTOKO MATSUFUJI, NAOTO KAWAMURA, TAKASHI SAKAI, TOMOHIRO SAMESHIMA, YOSHIHARU MIZUI

المصدر: The Journal of Antibiotics. 2004, 57(3):173

المؤلفون: AKIFUMI OKUDA, NAOKI ASAI, NAOTO KAWAMURA, TAKASHI SAKAI, YOSHIHARU MIZUI

المصدر: The Journal of Antibiotics. 2004, 57(3):180

المؤلفون: Josep Tabernero, José Baselga, Maria Josepa Carreras, Erik A.C. Wiemer, Yoshiharu Mizui, Maja J.A. de Jonge, Adelaida Piera, James P. O'Brien, Herman Burger, Francisco J. Ramos, Ferry A.L.M. Eskens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbdde1c1e931bfc90e466159624880c
https://doi.org/10.1158/1078-0432.22452234.v1

المؤلفون: Josep Tabernero, José Baselga, Maria Josepa Carreras, Erik A.C. Wiemer, Yoshiharu Mizui, Maja J.A. de Jonge, Adelaida Piera, James P. O'Brien, Herman Burger, Francisco J. Ramos, Ferry A.L.M. Eskens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e0f8260b7371e2b5d59a35ea175a95
https://doi.org/10.1158/1078-0432.22452231.v1

المؤلفون: Josep Tabernero, José Baselga, Maria Josepa Carreras, Erik A.C. Wiemer, Yoshiharu Mizui, Maja J.A. de Jonge, Adelaida Piera, James P. O'Brien, Herman Burger, Francisco J. Ramos, Ferry A.L.M. Eskens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb6f86ea39c80ed2d3bbca08767fc4f
https://doi.org/10.1158/1078-0432.c.6522423.v1

المؤلفون: Zhenhua Jeremy Wu, Ermira Pazolli, Pete Smith, James Palacino, Deepti Banka, Craig Furman, Yoshiharu Mizui, Cheryl Eifert, Silvia Buonamici, Daniel Aird, Teng Teng, Craig Karr, Kahlin Cheung-Ong, Eunice Park, Agustin Chicas, Ping Zhu, Chia-Ling Huang, Markus Warmuth, Peter Fekkes, Laura Corson, Lihua Yu, Michael Seiler

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, General Physics and Astronomy, Apoptosis, 02 engineering and technology, Mice, RNA interference, Carcinoma, Non-Small-Cell Lung, MCL1, RNA, Small Interfering, lcsh:Science, Melanoma, Multidisciplinary, Drug Synergism, 021001 nanoscience & nanotechnology, Proto-Oncogene Proteins c-bcl-2, Doxycycline, RNA splicing, Female, RNA Interference, Macrolides, 0210 nano-technology, Spliceosome, RNA Splicing, Science, bcl-X Protein, Mice, Nude, Antineoplastic Agents, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Minor Histocompatibility Antigens, 03 medical and health sciences, Cell Line, Tumor, Exome Sequencing, Animals, Humans, Gene, RNA, General Chemistry, Xenograft Model Antitumor Assays, 030104 developmental biology, A549 Cells, Cancer cell, Spliceosomes, Cancer research, Epoxy Compounds, Myeloid Cell Leukemia Sequence 1 Protein, lcsh:Q, Apoptosis Regulatory Proteins, BCL2-related protein A1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303bb3dee6e038f2ad817fbea0780d3f
https://doaj.org/article/3d3b4213a3e7400997cdfc63d11b14e8

المؤلفون: Michael P. Thomas, Lihua Yu, Craig Karr, Eric Padron, Markus Warmuth, Teng Teng, Yoshiharu Mizui, Peter Fekkes, Eckley Sean, John Q. Wang, Omar Abdel-Wahab, Anant A. Agrawal, Alfredo Csibi, Michael Seiler, Huilan Yao, Carol Meeske, Ermira Pazolli, Benjamin Caleb, Akihide Yoshimi, Betty Chan, Eunice Park, Linda Lee, Ping Zhu, Stanley Chun-Wei Lee, Rachel Darman, Keaney Gregg F, Xiang Liu, Silvia Buonamici, Crystal MacKenzie, Virginia M. Klimek, Pete Smith, Shouyong Peng, Sudeep Prajapati, Pavan Kumar, Justin Taylor, W. George Lai

المصدر: Nature medicine. 24(4)

مصطلحات موضوعية: 0301 basic medicine, Spliceosome, Pyridines, RNA Splicing, Mutant, Administration, Oral, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, Piperazines, Small Molecule Libraries, 03 medical and health sciences, Mice, Neoplasms, medicine, Animals, Humans, RNA, Messenger, Gene, Mutation, Leukemia, Base Sequence, Chemistry, Intron, RNA, General Medicine, Xenograft Model Antitumor Assays, Introns, Cell biology, Tumor Burden, 030104 developmental biology, RNA splicing, Cancer cell, Spliceosomes, K562 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4078739ee0c363415f375eded064d591
https://pubmed.ncbi.nlm.nih.gov/29500297

المؤلفون: Huiming Zhang, Linda Lee, Sudeep Prajapati, Betty Chan, Kazunobu Kira, Mingde Shan, Laura Corson, Ming-Hong Hao, Kuo-Ming Wu, O'shea Morgan Welzel, Yoshiharu Mizui, Samantha Perino, John Wang, Eun Sun Park, Lisa A. Marcaurelle, Marta Nevalainen, Arai Kenzo, Guo-Zhu Zheng, Markus Warmuth, Lihua Yu, Atsushi Endo, Jason T. Lowe, Xiang Liu, Baudouin Gerard, Pete Smith, Tivitmahaisoon Parcharee, Craig Karr, Silvia Buonamici, Keaney Gregg F, Tuoping Luo

المصدر: Organic Letters. 16:5560-5563

مصطلحات موضوعية: RNA Splicing Factors, Stereochemistry, RNA Splicing, Mutant, Antineoplastic Agents, Biochemistry, chemistry.chemical_compound, Cell Line, Tumor, Humans, Physical and Theoretical Chemistry, Cell Proliferation, Binding Sites, Natural product, Drug discovery, Cell growth, Organic Chemistry, Total synthesis, Ribonucleoprotein, U2 Small Nuclear, Phosphoproteins, chemistry, RNA splicing, Epoxy Compounds, Macrolides, Growth inhibition

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60a255bfd7796bff2bb3d4c8b6a0b4b
https://doi.org/10.1021/ol502556c

المؤلفون: Saori Watanabe-Miyano, Kiyoshi Okamoto, Kazuki Miyazaki, Setsuo Funasaka, Yoshinobu Yamane, Yoshiharu Mizui, Yoichi Ozawa, Junichi Kamata, Keigo Tanaka, Daisuke Ito, Yoshihiko Kotake, Nagao Satoshi, Osamu Toyama

المصدر: Bioorganic & Medicinal Chemistry. 22:5513-5529

مصطلحات موضوعية: Hypoxia-Inducible Factor 1, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Small Molecule Libraries, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Drug Discovery, Gene expression, Humans, Structure–activity relationship, Anilides, Molecular Biology, Transcription factor, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Benzanilide, Small molecule, In vitro, High-Throughput Screening Assays, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10858306428f0891bf15ce593eb4e1cf
https://doi.org/10.1016/j.bmc.2014.07.020

المؤلفون: Daniel Aird, Teng Teng, Chia-Ling Huang, Ermira Pazolli, Deepti Banka, Kahlin Cheung-Ong, Cheryl Eifert, Craig Furman, Jeremy Wu, Michael Seiler, Silvia Buonamici, Peter Fekkes, Craig Karr, James Palacino, Eunice Park, Peter Smith, Lihua Yu, Yoshiharu Mizui, Markus Warmuth, Agustin Chicas, Laura Corson, Ping Zhu

المصدر: Cancer Research. 79:281-281

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::473ec6f6c690810952be1ec62a8c33ad
https://doi.org/10.1158/1538-7445.am2019-281

المؤلفون: Eunice Park, Silvia Buonamici, Agustin Chicas, Laura Corson, Xiaoling Puyang, Pete Smith, Betty Chan, Shouyong Peng, Jian Zou, Ping Zhu, Manav Korpal, Nicholas A. Larsen, Michael Seiler, Daniel Aird, Teng Teng, Jennifer Hc Tsai, Benjamin Caleb, Yoshiharu Mizui, Peter Fekkes, V. Subramanian, Lihua Yu, Jason T. Lowe, Xiang Liu, Zhenhua Jeremy Wu, Baudouin Gerard, Markus Warmuth, Jacob Feala, Sudeep Prajapati, James Palacino, Craig Karr

المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)

مصطلحات موضوعية: 0301 basic medicine, Adenosine, Protein Conformation, General Physics and Astronomy, RNA-binding protein, Plasma protein binding, Crystallography, X-Ray, Mass Spectrometry, Exon, 0302 clinical medicine, Genetics, Multidisciplinary, RNA-Binding Proteins, Exons, Recombinant Proteins, Cell biology, 030220 oncology & carcinogenesis, RNA splicing, RNA Interference, Macrolides, RNA Splicing Factors, Fatty Alcohols, Protein Binding, Spliceosome, Cell Survival, Science, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Humans, Spiro Compounds, Cell Proliferation, Pyrans, Sequence Analysis, RNA, Alternative splicing, Cryoelectron Microscopy, Intron, General Chemistry, HCT116 Cells, Phosphoproteins, Introns, Alternative Splicing, 030104 developmental biology, Mutation, Mutagenesis, Site-Directed, Spliceosomes, Trans-Activators, Epoxy Compounds, Myeloid Cell Leukemia Sequence 1 Protein, Herboxidiene, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163a1e80e4630732321afc5c9498ba49
https://pubmed.ncbi.nlm.nih.gov/28541300

المؤلفون: Kazuki Miyazaki, Yoichi Ozawa, Osamu Tohyama, Isao Tanaka, Makoto Asano, Nagao Satoshi, Yoshiharu Mizui, Setsuo Funasaka, Akira Yokoi, Saori Watanabe, Takanori Kawamura, Daisuke Ito, Yoshinobu Yamane, Yoshihiko Kotake, Kohei Sawada, Kiyoshi Okamoto, Junichi Kamata, Naoko Tsukahara, Mika Aoki

المصدر: International Journal of Molecular Medicine

مصطلحات موضوعية: medicine.medical_treatment, Cell, Administration, Oral, xenograft model, Antineoplastic Agents, Pharmacology, Biology, Piperazines, hypoxia-inducible factor 1, Mice, Cell Line, Tumor, Glioma, Genetics, medicine, Animals, Humans, Cell Proliferation, Mice, Inbred BALB C, Oncogene, hypoxia, Articles, General Medicine, Hypoxia (medical), Cell cycle, Hypoxia-Inducible Factor 1, alpha Subunit, medicine.disease, Xenograft Model Antitumor Assays, Cell Hypoxia, radiation, Radiation therapy, medicine.anatomical_structure, Apoptosis, Benzamides, Cancer cell, Female, medicine.symptom, small-molecule inhibitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83c096d2c3122ac21cb2a7d9b4ba1fb
https://doi.org/10.3892/ijmm.2011.875

المؤلفون: Masao Iwata, Naoko Hata Sugi, Yoshihiko Kotake, Yukinori Minoshima, Koji Sagane, Yoshiko Matsumoto, Makoto Hamaguchi, Akira Yokoi, Kentaro Takahashi, Yoshiharu Mizui, Tadashi Kadowaki

المصدر: FEBS Journal. 278:4870-4880

مصطلحات موضوعية: RNA Splicing Factors, Mutation, Immunoprecipitation, Cell growth, Protein subunit, Cell Biology, Biology, medicine.disease_cause, Biochemistry, Molecular biology, Cell culture, Mutant protein, RNA splicing, medicine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::48b646337d53acef20ab63864a425479
https://doi.org/10.1111/j.1742-4658.2011.08387.x

المؤلفون: Isao Tanaka, Fabian Gusovsky, Masanori Fujita, Jesse Chow, Yuan J. Wang, Masaki Goto, Hua Yang, Yoshiharu Mizui, Donna W. Young, Satoshi Yamamoto, Kenichi Chiba, Kenji Tai, Hiroshi Obaishi, Hiroshi Shirota, Kenzo Muramoto

المصدر: Journal of Pharmacology and Experimental Therapeutics. 331:485-495

مصطلحات موضوعية: Pharmacology, MAP kinase kinase kinase, Cyclin-dependent kinase 4, Cyclin-dependent kinase 2, Biology, Mitogen-activated protein kinase kinase, Molecular biology, Protein kinase R, MAP2K7, Biochemistry, biology.protein, Molecular Medicine, Cyclin-dependent kinase 9, c-Raf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4c12f63c04c9f9381c17aa7e714b17e1
https://doi.org/10.1124/jpet.109.156554

المؤلفون: Masao Iwata, Yoshihiko Kotake, Takashi Owa, Yasushi Ishihama, Yuko Mimori-Kiyosue, Mai Uesugi, Koji Sagane, Hajime Shimizu, Yoshiharu Mizui

المصدر: Nature Chemical Biology. 3:570-575

مصطلحات موضوعية: Reporter gene, Splicing factor, Biochemistry, Cell growth, Protein subunit, RNA splicing, Cell Biology, Target protein, Biology, Herboxidiene, Molecular Biology, Fusion protein, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4b79c8bfe60af1b00339c4b3e2be79c8
https://doi.org/10.1038/nchembio.2007.16