المؤلفون: Nikhil Kumar Tulsian, Raghuvamsi Venkata Palur, Xinlei Qian, Yue Gu, Bhuvaneshwari D/O Shunmuganathan, Firdaus Samsudin, Yee Hwa Wong, Jianqing Lin, Kiren Purushotorman, Mary McQueen Kozma, Bei Wang, Julien Lescar, Cheng-I Wang, Ravindra Kumar Gupta, Peter John Bond, Paul Anthony MacAry

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/54f52c1fa0c948c5b812e8554189a002

المؤلفون: Niying Chua, Yee Hwa Wong, Abbas El Sahili, Chuan Fa Liu, Julien Lescar

المصدر: FEBS Open Bio, Vol 13, Iss 6, Pp 1095-1106 (2023)

مصطلحات موضوعية: asparaginyl endopeptidase, peptide asparaginyl ligase, peptide cyclization, protein conjugation, protein refolding, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2211-5463

URL الوصول: https://doaj.org/article/5dfed74a53e64c6b9d8ed6c9eaef0452

المؤلفون: Yue Gu, Robynne W. K. Koh, May Ling Lai, Denise Pochinco, Rachel Z. C. Teo, Marieta Chan, Tanusya M. Murali, Chong Wai Liew, Yee Hwa Wong, Nicholas R. J. Gascoigne, Kathryn J. Wood, Julien Lescar, Peter Nickerson, Paul A. MacAry, Anantharaman Vathsala

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/0d892bb6ce394324a9db08fda50ac687

المؤلفون: Yue Gu, Yee Hwa Wong, Chong Wai Liew, Conrad E. Z. Chan, Tanusya M. Murali, Jiawei Yap, Chien Tei Too, Kiren Purushotorman, Maryam Hamidinia, Abbas El Sahili, Angeline T. H. Goh, Rachel Z. C. Teo, Kathryn J. Wood, Brendon J. Hanson, Nicholas R. J. Gascoigne, Julien Lescar, Anantharaman Vathsala, Paul A. MacAry

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/d43685122a4b496da7e60656bb9c199a

المؤلفون: Nikhil Tulsian, Palur Raghuvamsi, Xinlei Qian, Yue Gu, Bhuvaneshwari D/O Shunmuganathan, Firdaus Samsudin, Yee Hwa Wong, Jianqing Lin, Kiren Purushotorman, Mary Kozma, BEI WANG, Julien Lescar, Cheng-I Wang, Ravindra Gupta, Peter Bond, Paul MacAry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bd2e04aa582f3a355e27b325f33512af
https://doi.org/10.21203/rs.3.rs-2465199/v1

المؤلفون: Side Hu, Abbas El Sahili, Srujana Kishore, Yee Hwa Wong, Xinya Hemu, Boon Chong Goh, Zhen Wang, James P. Tam, Chuan-Fa Liu, Julien Lescar

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9497a83c45f22f4c44aba37bdcec95ac
https://doi.org/10.1101/2021.12.09.471967

المؤلفون: Side Hu, Abbas El Sahili, Srujana Kishore, Yee Hwa Wong, Xinya Hemu, Boon Chong Goh, Sang Zhipei, Zhen Wang, James P Tam, Chuan-Fa Liu, Julien Lescar

المصدر: The Plant cell. 34(12)

مصطلحات موضوعية: Ligases, Enzyme Precursors, Proteins, Cell Biology, Plant Science, Peptides, Substrate Specificity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485a2dca3cba19b5f6a37021dc97da09
https://pubmed.ncbi.nlm.nih.gov/36099055

المؤلفون: Kalyan Kumar Pasunooti, Pooja Gopal, Shanmugavel Gnanakalai, Nelson B. Olivier, Siau Hoi Lim, Julien Lescar, Seetharamsing Balamkundu, Vinod Gadi, Wenhe Zhong, Peter C. Dedon, Chuan-Fa Liu, Yok Hian Chionh, Ed T. Buurman, Thomas Dick, Megan E. McBee, Qianhui Nah, Yee Hwa Wong

المساهمون: School of Biological Sciences, Singapore-MIT Alliance for Research and Technology, Institute of Structural Biology

المصدر: Journal of Medicinal Chemistry. 62:7788-7805

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Conformational change, Methyltransferase, biology, Inhibitors, Biological sciences [Science], Active site, 01 natural sciences, In vitro, Cofactor, 0104 chemical sciences, Peptides and Proteins, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Enzyme, chemistry, Biochemistry, Drug Discovery, Transfer RNA, biology.protein, Molecular Medicine, Tyrosine, 030304 developmental biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550e33b18ac78640a1f11420a6243e12
https://doi.org/10.1021/acs.jmedchem.9b00582

المؤلفون: Somchart Maenpuen, Narumon Thongdee, Erin G. Prestwich, Skorn Mongkolsuk, Wenhe Zhong, Abbas El Sahili, Sopapan Atichartpongkul, Yok Hian Chionh, Megan E. McBee, Julien Lescar, Chong Wai Liew, Juthamas Jaroensuk, Pimchai Chaiyen, Yee Hwa Wong, Peter C. Dedon, Michael S. DeMott, Mayuree Fuangthong, Qianhui Nah

المصدر: RNA. 25:1481-1496

مصطلحات موضوعية: 0301 basic medicine, TRNA modification, Stereochemistry, TRNA Methyltransferase, Isothermal titration calorimetry, Biology, 03 medical and health sciences, Sinefungin, 030104 developmental biology, Non-competitive inhibition, Transfer RNA, Transferase, Molecular Biology, Ternary complex

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::10d0f9510160f0ccf682b4a455242e3b
https://doi.org/10.1261/rna.066746.118

المؤلفون: Julien Lescar, Yee Hwa Wong, Hui Qi Ng, Jeffrey Hill, Ann Zhufang Koay, Peter C. Dedon, CongBao Kang, Wenhe Zhong, Qianhui Nah, Yan Li

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering

المصدر: Josephina Lee

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Methyltransferase, biology, Stereochemistry, Dimer, 030303 biophysics, Translation (biology), Biochemistry, TRNA binding, Cofactor, Amino acid, 03 medical and health sciences, chemistry.chemical_compound, chemistry, Structural Biology, Transfer RNA, biology.protein, Protein secondary structure, 030304 developmental biology

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897348e9c8823878e68052427c740503
https://doi.org/10.1007/s12104-019-09900-2

المؤلفون: Roderick W. Bates, Sridhar Santhanakrishnan, Julien Lescar, Abbas El Sahili, Subhash G. Vasudevan, Siok Thing Tan, Yee Hwa Wong, Aïcha Gharbi-Ayachi, Kitti Wing Ki Chan

المساهمون: School of Biological Sciences, School of Physical and Mathematical Sciences, Nanyang Institute of Structural Biology

المصدر: J Virol

مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, viruses, Gene Expression, Dengue virus, medicine.disease_cause, Virus Replication, Zika virus, Substrate Specificity, chemistry.chemical_compound, RNA polymerase, Sulfones, Polymerase, 0303 health sciences, biology, Zika Virus Infection, Biological sciences [Science], Recombinant Proteins, Flavivirus, Allosteric Site, Protein Binding, medicine.drug_class, Immunology, RNA-dependent RNA polymerase, Thiophenes, Microbiology, Antiviral Agents, Polymerase Inhibitors, 03 medical and health sciences, Structure-Activity Relationship, Viral Proteins, Nonstructural Protein 5, Cricetulus, Allosteric Regulation, Virology, Cell Line, Tumor, Vaccines and Antiviral Agents, medicine, Animals, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, 030304 developmental biology, Binding Sites, 030306 microbiology, Zika Virus, biology.organism_classification, RNA-Dependent RNA Polymerase, Kinetics, Viral replication, chemistry, Insect Science, Drug Design, biology.protein, Hepatocytes, Protein Conformation, beta-Strand, Antiviral drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a223d849ddbbc074ec887748c51cffb5
https://europepmc.org/articles/PMC7565630/

المؤلفون: Julien Lescar, Angeline T. H. Goh, Yee Hwa Wong, Rachel Zui Chih Teo, Jiawei Yap, Abbas El Sahili, Maryam Hamidinia, Kathryn J. Wood, Conrad E.Z. Chan, Nicholas R. J. Gascoigne, Tanusya M. Murali, Kiren Purushotorman, Brendon J. Hanson, Chong Wai Liew, Chien Tei Too, Anantharaman Vathsala, Yue Gu, Paul A. MacAry

المساهمون: School of Biological Sciences, NTU Institute of Structural Biology

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Conformation, Science, General Physics and Astronomy, Context (language use), Antigen-Antibody Complex, 02 engineering and technology, Human leukocyte antigen, Crystallography, X-Ray, Article, General Biochemistry, Genetics and Molecular Biology, HLA-A11 Antigen, MHC Class I, Epitopes, 03 medical and health sciences, Antibody Specificity, Isoantibodies, Peptide Library, MHC class I, Humans, Amino Acid Sequence, lcsh:Science, HLA Complex, Multidisciplinary, biology, Alloimmunity, T-cell receptor, Allotransplantation, Antibodies, Monoclonal, General Chemistry, 021001 nanoscience & nanotechnology, HLA-A, Science::Biological sciences [DRNTU], 030104 developmental biology, Immunoglobulin G, Immunology, biology.protein, lcsh:Q, Binding Sites, Antibody, Antibody, 0210 nano-technology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a12f0fbf74a9110ef580a79127b5631
https://doaj.org/article/d43685122a4b496da7e60656bb9c199a

المؤلفون: Yee Hwa Wong, CongBao Kang, Xiaoying Koh-Stenta, Alex Matter, Wenhe Zhong, Hui Qi Ng, Klement Foo, Megan E. McBee, Ann Koay, Anders Poulsen, Julien Lescar, Jeffrey Hill, Abbas El Sahili, Qianhui Nah, Yan Li, Yok Hian Chionh, Anna Ngo, Meng Ling Choong, Peter C. Dedon

المساهمون: School of Biological Sciences, NTU Institute of Structural Biology, Singapore-MIT Alliance for Research and Technology

المصدر: ACS Infectious Diseases. 5:326-335

مصطلحات موضوعية: 0301 basic medicine, TRNA modification, Methyltransferase, biology, Chemistry, High-throughput screening, 030106 microbiology, Biological sciences [Science], tRNA Modification, biology.organism_classification, 03 medical and health sciences, 030104 developmental biology, Infectious Diseases, Biochemistry, Enzyme inhibitor, High-throughput Screening, Transfer RNA, biology.protein, Transferase, Antibacterial activity, Bacteria

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba136b2d4dbc1e07c0350f39a81a8c5
https://doi.org/10.1021/acsinfecdis.8b00275

المؤلفون: Wenhe Zhong, Kuohan Li, Cai, Qixu, Jingjing Guo, Meng Yuan, Yee Hwa Wong, Malcom D. Walkinshaw, Linda A. Fothergill-Gilmore, Paul A.M. Michels, Pter C. Dedon, Julien Lescar

مصطلحات موضوعية: Allostery, Crystal structures, Kinases, Kinetics

Relation: http://repository.ust.hk/ir/Record/1783.1-105357; Biochemical and Biophysical Research Communications, v. 532, (3), 12 November 2020, p. 370-376; https://doi.org/10.1016/j.bbrc.2020.08.048; http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=0006-291X&rft.volume=&rft.issue=&rft.date=2020&rft.spage=&rft.aulast=Zhong&rft.aufirst=&rft.atitle=Pyruvate+kinase+from+Plasmodium+falciparum%3A+Structural+and+kinetic+insights+into+the+allosteric+mechanism&rft.title=Biochemical+and+Biophysical+Research+Communications; http://www.scopus.com/record/display.url?eid=2-s2.0-85090001444&origin=inward; http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000577987300007

الاتاحة: http://repository.ust.hk/ir/Record/1783.1-105357
https://doi.org/10.1016/j.bbrc.2020.08.048
http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=0006-291X&rft.volume=&rft.issue=&rft.date=2020&rft.spage=&rft.aulast=Zhong&rft.aufirst=&rft.atitle=Pyruvate+kinase+from+Plasmodium+falciparum%3A+Structural+and+kinetic+insights+into+the+allosteric+mechanism&rft.title=Biochemical+and+Biophysical+Research+Communications
http://www.scopus.com/record/display.url?eid=2-s2.0-85090001444&origin=inward
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000577987300007

المؤلفون: Yee Hwa Wong, James P. Tam, Renliang Yang, Julien Lescar, Bin Wu, Giang K. T. Nguyen

المصدر: Journal of the American Chemical Society. 139:5351-5358

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Proteases, Stereochemistry, Peptide, Protein Engineering, Biochemistry, Catalysis, law.invention, Ligases, Oldenlandia, 03 medical and health sciences, Colloid and Surface Chemistry, law, Hydrolase, chemistry.chemical_classification, DNA ligase, General Chemistry, Protein engineering, Recombinant Proteins, 030104 developmental biology, Enzyme, chemistry, Biocatalysis, Recombinant DNA, Cyclase activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7641683c5ec4915282b3a3573781a44
https://doi.org/10.1021/jacs.6b12637

المؤلفون: Yee Hwa Wong, Peter Nickerson, Nicholas R. J. Gascoigne, Denise Pochinco, May Ling Lai, Kathryn J. Wood, Julien Lescar, Paul A. MacAry, Chong Wai Liew, Robynne W. K. Koh, Rachel Zui Chih Teo, Anantharaman Vathsala, Marieta Chan, Yue Gu, Tanusya M. Murali

المساهمون: School of Biological Sciences, NTU Institute of Structural Biology

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: Science, Patient risk, Immunology, Human leukocyte antigen, 030230 surgery, Microbiology, Subclass, Article, 03 medical and health sciences, 0302 clinical medicine, Medical research, HLA Antigens, Medicine, Humans, Clinical significance, Single antigen bead, Multidisciplinary, biology, Molecular Structure, business.industry, Antibodies, Monoclonal, Biological sciences [Science], Medical Research, Transplantation, Nephrology, Monoclonal, biology.protein, Antibody, business, Algorithms, 030215 immunology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080d88f66d3174477a2e9a963b05ad5e
https://hdl.handle.net/10356/146045

المؤلفون: Wenhe, Zhong, Kalyan Kumar, Pasunooti, Seetharamsing, Balamkundu, Yee Hwa, Wong, Qianhui, Nah, Vinod, Gadi, Shanmugavel, Gnanakalai, Yok Hian, Chionh, Megan E, McBee, Pooja, Gopal, Siau Hoi, Lim, Nelson, Olivier, Ed T, Buurman, Thomas, Dick, Chuan Fa, Liu, Julien, Lescar, Peter C, Dedon

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: Models, Molecular, Structure-Activity Relationship, tRNA Methyltransferases, Binding Sites, Pyrimidines, Dose-Response Relationship, Drug, Molecular Structure, Drug Design, Pseudomonas aeruginosa, Tyrosine, Enzyme Inhibitors, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::6e127326354feb5fa511e9e28cdebdd6
https://pubmed.ncbi.nlm.nih.gov/31442049

المؤلفون: Chuan-Fa Liu, Xinya Hemu, Aida Serra, Dina Amallia Darwis, Xiaohong Zhang, Yee Hwa Wong, Abbas El Sahili, Siu Kwan Sze, James P. Tam, Side Hu, Yu Chen, Julien Lescar, Boon Chong Goh, Kaho Wong, Ming Wei Chen

المساهمون: School of Biological Sciences, NTU Institute of Structural Biology

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(24)

مصطلحات موضوعية: chemistry.chemical_classification, DNA ligase, Multidisciplinary, Protease, Stereochemistry, Science, medicine.medical_treatment, Mutagenesis, Peptide, Asparaginyl Ligase, Peptides, Cyclic, Cyclic peptide, humanities, Cyclopeptide, Ligases, Cysteine Endopeptidases, chemistry, PNAS Plus, medicine, Peptide bond, Ligase activity, Violaceae, Cysteine, Plant Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e76aa06e173bc74efdbd77b6249fe6
https://pubmed.ncbi.nlm.nih.gov/31123145

المؤلفون: Yan, Li, Wenhe, Zhong, Ann Zhufang, Koay, Hui Qi, Ng, Qianhui, Nah, Yee Hwa, Wong, Jeffrey, Hill, Julien, Lescar, Peter C, Dedon, CongBao, Kang

المصدر: Biomolecular NMR assignments. 13(2)

مصطلحات موضوعية: Models, Molecular, tRNA Methyltransferases, Protein Domains, Pseudomonas aeruginosa, Nuclear Magnetic Resonance, Biomolecular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a6bbd5eadfce9ec8c61cb3ac2efb4325
https://pubmed.ncbi.nlm.nih.gov/31175551

المؤلفون: Narumon Thongdee, Julien Lescar, Juthamas Jaroensuk, Michael S. DeMott, Chong Wai Liew, Mayuree Fuangthong, Yee Hwa Wong, Yok Hian Chionh, Sopapan Atichartpongkul, Skorn Mongkolsuk, Peter C. Dedon, Megan E. McBee, Erin G. Prestwich

المساهمون: Chulabhorn Research Institute, Singapore-MIT Alliance for Research and Technology (SMART), Massachusetts Institute of Technology (MIT), Nanyang Technological University [Singapour], Mahidol University [Bangkok], Center of excellence on environmental health and toxicology, Bangkok, Centre d'Immunologie et de Maladies Infectieuses (CIMI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Massachusetts Institute of Technology. Department of Biological Engineering, Chionh, Yok Hian, DeMott, Michael S, Dedon, Peter C, HAL UPMC, Gestionnaire

المصدر: Nucleic Acids Research
Nucleic Acids Research, 2016, 44 (22), pp.10834-10848. ⟨10.1093/nar/gkw870⟩
Oxford University Press
Nucleic Acids Research, Oxford University Press, 2016, 44 (22), pp.10834-10848. ⟨10.1093/nar/gkw870⟩

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, [SDV]Life Sciences [q-bio], Mutant, Crystallography, X-Ray, medicine.disease_cause, Methylation, 03 medical and health sciences, Sinefungin, Bacterial Proteins, RNA, Transfer, Catalytic Domain, Gene expression, Genetics, medicine, Amino Acid Sequence, Escherichia coli, tRNA Methyltransferases, Base Sequence, 030102 biochemistry & molecular biology, biology, Nucleic Acid Enzymes, Active site, Hydrogen Peroxide, Molecular biology, [SDV] Life Sciences [q-bio], Oxidative Stress, RNA, Bacterial, 030104 developmental biology, Biochemistry, Pseudomonas aeruginosa, Transfer RNA, biology.protein, T arm

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ca8694e4caaaaf4dfd2356adbe83a5
https://doi.org/10.1093/nar/gkw870